Purpose: This study was conducted in order to evaluate the antidiabetic effects of the aqueous extract of Lippia multiflora supplemented with magnesium on some biochemical markers of the kidneys and liver in type 2 di...Purpose: This study was conducted in order to evaluate the antidiabetic effects of the aqueous extract of Lippia multiflora supplemented with magnesium on some biochemical markers of the kidneys and liver in type 2 diabetic rats. Method: 7 groups of 4 STZ-diabetic rats received separately orally Glucophage<sup>®</sup> (Glu 10 mg/kg), the plant extract (LiMAE 200 - 600 mg/kg) and the plant extract supplemented with magnesium (LiMAE-Mg 200 - 600 mg/kg). After a daily treatment of 21 days, serum biochemical parameters were assayed in 16 hr-fasted rats. Results: Diabetes caused a significant (p Conclusion: The addition of magnesium to the extract of Lippia multiflora caused a greater reduction in the levels of urea, creatinine, ALT and AST increased in STZ-diabetic rats. Magnesium would therefore enhance the nephroprotective and hepatoprotective effects of Lippia multiflora in diabetic rats.展开更多
Essential oil (EO) of Nigeria-grown Lippia adoensis leaf was analyzed using gas chromatography mass spectrometry (GCMS) and its fumigant and repellent properties against Callosobruchus maculatus were evaluated. Si...Essential oil (EO) of Nigeria-grown Lippia adoensis leaf was analyzed using gas chromatography mass spectrometry (GCMS) and its fumigant and repellent properties against Callosobruchus maculatus were evaluated. Sixteen compounds predominated by monoterpenes were identified. The major compounds were Eucalyptol (28.36%), α-Terpineol (25.99%), γ-Terpinene (15.24%), α-Pinene (5.08%), 1H-Cyclopropa[a]naphthalene (4.25%) and 1, 3, 6, 10-Dodeeatetraene (3.74%). Percentage mortality due to fumigant toxicity was dose- and exposure period-dependent. One hour after treatment (HAT), application of L. adoensis leaf EO at 107 μL· L^-1 air caused significantly (p〈0.05) higher mortality (50.00%) than 0.00% mortality observed at 0-53 μL· L^-1 air, but not significantly (p〉0.05) different from 22.50% observed in 80 μL· L^-1 air. At 3 HAT, application ofL. adoensis EO at 80 μL· L^-1 air caused significantly higher mortality (90.00 %) than mortality observed at 0 μL· L^-1 air. At 6 HAT, application of L. adoensis EO at 53-107 μL· L^-1 air caused significantly higher mortality (100.00 %) than that was observed in the control. The same trend was observed at 12 HAT where 100 % mortality observed in 27-107 μL· L^-1 air was significantly greater than 13.33 % observed in the control. At 3 HAT, percentage repellence was significantly (p〈0.05) affected by doses. Application of EO at 10-30 μL· cm^2 caused class V repellence (86.67%-100%) compared with the control which caused class I repellence (0-20%).展开更多
This study aims to determine the mineral composition of green teas and herbal tea in the savannah tea plant. Samples of buds, young leaves and broadleaf stems were collected from wild plants of Lippia multiflora in th...This study aims to determine the mineral composition of green teas and herbal tea in the savannah tea plant. Samples of buds, young leaves and broadleaf stems were collected from wild plants of Lippia multiflora in three localities, including two from the Center (Yamoussoukro, Toumodi) and one from the northeast (Bondoukou) of Côte d’Ivoire. The lipid and ash contents were carried out by the AOAC method. The total protein and sugar contents were determined by the Kjeldahl and Agbo methods, respectively. Nine minerals (potassium, calcium, magnesium, iron, sodium, manganese, zinc, copper and cadmium) were quantitated by Atomic Absorption Spectrophotometry (AAS) from green teas (buds and young leaves) and herbal tea of Lippia multiflora. The results showed that ash levels (7.05% - 13.94%) and protein (6.22% - 9.97%) were high, however the lipid contents (1.01% - 2.98%) and total sugars (1.43% - 4.51%) are low. Majority of the minerals are calcium (2320.91 to 36150.10 mg/kg), potassium (2110.71 to 12174.67 mg/kg) and magnesium (3620.87 - 5870.46 mg/kg). Iron (52.55 to 483.11 mg/kg), sodium (35.66 to 469.16 mg/kg) and manganese (15.25 to 76.86 mg/kg) are represented in average proportions. There are small amounts of zinc (9.61 - 47.50 mg/kg), copper (5.66 - 8.71 mg/kg), and cadmium (0.17 - 1.49 mg/kg). Lippia multiflora herbal teas and green teas are low in fat, high in ash and are good sources of protein and minerals.展开更多
To analyze the nutritional value as feed,the aerial stem and leaves of Lippia nodiflora( L.) Greene and Phyla nodiflora( L.) Greene were sampled to measure the nutritional indices. The nutritional indices were also co...To analyze the nutritional value as feed,the aerial stem and leaves of Lippia nodiflora( L.) Greene and Phyla nodiflora( L.) Greene were sampled to measure the nutritional indices. The nutritional indices were also compared with common forage grass,and the development value of L. nodiflora as feed was analyzed. Compared with P. nodiflora,L. nodiflora had obvious fast-growing and high-yield abilities. The contents of crude fat,crude fiber,crude ash,lysine,vitamin C,Ca,and Fe in L. nodiflora were obviously higher than that in P. nodiflora,but the content of crude protein and total P in L. nodiflora were significantly lower than that in P. nodiflora. Compared with common forage feed ryegrass,alfalfa,millet straw and corn straw,L. nodiflora had higher contents of crude fat and crude ash and lower contents of crude fiber and crude protein. Therefore,L. nodiflora had higher development value as feed.展开更多
Phytochemical studies and antioxidant activities were carried out on n-hexane, ethyl acetate, ethanol and methanol extracts of the leaves of Lippia rugosa A. Chev (Verbenaceae), a medicinal plant used traditionally in...Phytochemical studies and antioxidant activities were carried out on n-hexane, ethyl acetate, ethanol and methanol extracts of the leaves of Lippia rugosa A. Chev (Verbenaceae), a medicinal plant used traditionally in the Cameroonian savannah’s region to protect foodstuffs and to cure degenerative diseases. Results indicated that theses extracts contain terpenoids, phenolic and flavonoid compounds. Except the n-hexane extract, all of the obtained extracts exhibit antioxidant activities with the ethanol extract being the most effective with an inhibition percentage of 85.668% ± 1.233% and an inhibition concentration (IC<sub>50</sub>) of 58 μg/ml (R<sup>2</sup> = 0.987, P < 0.01) at a concentration of 100 mg/ml. Chromatographic separation on silica gel of the ethanol extract led to the isolation of a pure organic compound which was characterized as 7-hydroxy-5,6,4'-trimethox- yflavone by extensive 1D and 2D NMR spectroscopy, a flavonoid exhibiting antioxidative activity with an inhibitory percentage of 25.506% ± 0.205% and inhibition concentration (IC<sub>50</sub>) of 221 μg/ml (R<sup>2</sup> = 0.966, P < 0.01). This is the first time that 7-hydroxy-5,6,4'-trimethoxyflavone is being isolated from L. rugosa and its antioxidant activity evaluated.展开更多
发热茶为马鞭草科植物Lippia javanica(Burm.f.)Spreng.,原产于非洲中部、东部和南部,多用于治疗感冒、咳嗽、疟疾、腹泻、痢疾等疾病。采用外来中药研究方法,本文对Web of Science、PubMed、CNKI等数据库中发热茶的文献进行研究,以临...发热茶为马鞭草科植物Lippia javanica(Burm.f.)Spreng.,原产于非洲中部、东部和南部,多用于治疗感冒、咳嗽、疟疾、腹泻、痢疾等疾病。采用外来中药研究方法,本文对Web of Science、PubMed、CNKI等数据库中发热茶的文献进行研究,以临床应用文献为导向,结合中医药理论对发热茶的中药药性进行理论分析。通过分析和综合归纳,将发热茶的中药药性概括为辛、苦、凉,归肺、大肠经,可疏散风热、清热燥湿、杀虫截疟,用于治疗风热感冒、湿热泻痢、虫积腹痛、疟疾寒热;外治湿疹湿疮,蜱虫。水煎服,每日用量为1~2 g;外用适量。发热茶药理作用和治病特点突出,又可内外同治,具有独特的药用价值。本文首次赋予发热茶中药药性,明确其中药性能有利于辨证施治,便于与其他中药配伍使用,为推广扩大其应用奠定基础。展开更多
文摘Purpose: This study was conducted in order to evaluate the antidiabetic effects of the aqueous extract of Lippia multiflora supplemented with magnesium on some biochemical markers of the kidneys and liver in type 2 diabetic rats. Method: 7 groups of 4 STZ-diabetic rats received separately orally Glucophage<sup>®</sup> (Glu 10 mg/kg), the plant extract (LiMAE 200 - 600 mg/kg) and the plant extract supplemented with magnesium (LiMAE-Mg 200 - 600 mg/kg). After a daily treatment of 21 days, serum biochemical parameters were assayed in 16 hr-fasted rats. Results: Diabetes caused a significant (p Conclusion: The addition of magnesium to the extract of Lippia multiflora caused a greater reduction in the levels of urea, creatinine, ALT and AST increased in STZ-diabetic rats. Magnesium would therefore enhance the nephroprotective and hepatoprotective effects of Lippia multiflora in diabetic rats.
基金Supported by the Senate of Ladoke Akintola University of Technology(LAUTECH)Ogbomoso,Nigeria Under the University Senate Research(LAU/SRG/13/045)
文摘Essential oil (EO) of Nigeria-grown Lippia adoensis leaf was analyzed using gas chromatography mass spectrometry (GCMS) and its fumigant and repellent properties against Callosobruchus maculatus were evaluated. Sixteen compounds predominated by monoterpenes were identified. The major compounds were Eucalyptol (28.36%), α-Terpineol (25.99%), γ-Terpinene (15.24%), α-Pinene (5.08%), 1H-Cyclopropa[a]naphthalene (4.25%) and 1, 3, 6, 10-Dodeeatetraene (3.74%). Percentage mortality due to fumigant toxicity was dose- and exposure period-dependent. One hour after treatment (HAT), application of L. adoensis leaf EO at 107 μL· L^-1 air caused significantly (p〈0.05) higher mortality (50.00%) than 0.00% mortality observed at 0-53 μL· L^-1 air, but not significantly (p〉0.05) different from 22.50% observed in 80 μL· L^-1 air. At 3 HAT, application ofL. adoensis EO at 80 μL· L^-1 air caused significantly higher mortality (90.00 %) than mortality observed at 0 μL· L^-1 air. At 6 HAT, application of L. adoensis EO at 53-107 μL· L^-1 air caused significantly higher mortality (100.00 %) than that was observed in the control. The same trend was observed at 12 HAT where 100 % mortality observed in 27-107 μL· L^-1 air was significantly greater than 13.33 % observed in the control. At 3 HAT, percentage repellence was significantly (p〈0.05) affected by doses. Application of EO at 10-30 μL· cm^2 caused class V repellence (86.67%-100%) compared with the control which caused class I repellence (0-20%).
文摘This study aims to determine the mineral composition of green teas and herbal tea in the savannah tea plant. Samples of buds, young leaves and broadleaf stems were collected from wild plants of Lippia multiflora in three localities, including two from the Center (Yamoussoukro, Toumodi) and one from the northeast (Bondoukou) of Côte d’Ivoire. The lipid and ash contents were carried out by the AOAC method. The total protein and sugar contents were determined by the Kjeldahl and Agbo methods, respectively. Nine minerals (potassium, calcium, magnesium, iron, sodium, manganese, zinc, copper and cadmium) were quantitated by Atomic Absorption Spectrophotometry (AAS) from green teas (buds and young leaves) and herbal tea of Lippia multiflora. The results showed that ash levels (7.05% - 13.94%) and protein (6.22% - 9.97%) were high, however the lipid contents (1.01% - 2.98%) and total sugars (1.43% - 4.51%) are low. Majority of the minerals are calcium (2320.91 to 36150.10 mg/kg), potassium (2110.71 to 12174.67 mg/kg) and magnesium (3620.87 - 5870.46 mg/kg). Iron (52.55 to 483.11 mg/kg), sodium (35.66 to 469.16 mg/kg) and manganese (15.25 to 76.86 mg/kg) are represented in average proportions. There are small amounts of zinc (9.61 - 47.50 mg/kg), copper (5.66 - 8.71 mg/kg), and cadmium (0.17 - 1.49 mg/kg). Lippia multiflora herbal teas and green teas are low in fat, high in ash and are good sources of protein and minerals.
基金Supported by 948 Program of State Forestry Administration"Vegetation Restoration Material Lippia nodiflorav for Rock Desertification Area in Gorge and Introduction of Its Cultivation and Breeding Technology"(2009-2012)Chongqing Key Laboratory of Three Gorges Area Forest Ecological Protectionand Restoration(CSTC,2007CA1001)
文摘To analyze the nutritional value as feed,the aerial stem and leaves of Lippia nodiflora( L.) Greene and Phyla nodiflora( L.) Greene were sampled to measure the nutritional indices. The nutritional indices were also compared with common forage grass,and the development value of L. nodiflora as feed was analyzed. Compared with P. nodiflora,L. nodiflora had obvious fast-growing and high-yield abilities. The contents of crude fat,crude fiber,crude ash,lysine,vitamin C,Ca,and Fe in L. nodiflora were obviously higher than that in P. nodiflora,but the content of crude protein and total P in L. nodiflora were significantly lower than that in P. nodiflora. Compared with common forage feed ryegrass,alfalfa,millet straw and corn straw,L. nodiflora had higher contents of crude fat and crude ash and lower contents of crude fiber and crude protein. Therefore,L. nodiflora had higher development value as feed.
文摘Phytochemical studies and antioxidant activities were carried out on n-hexane, ethyl acetate, ethanol and methanol extracts of the leaves of Lippia rugosa A. Chev (Verbenaceae), a medicinal plant used traditionally in the Cameroonian savannah’s region to protect foodstuffs and to cure degenerative diseases. Results indicated that theses extracts contain terpenoids, phenolic and flavonoid compounds. Except the n-hexane extract, all of the obtained extracts exhibit antioxidant activities with the ethanol extract being the most effective with an inhibition percentage of 85.668% ± 1.233% and an inhibition concentration (IC<sub>50</sub>) of 58 μg/ml (R<sup>2</sup> = 0.987, P < 0.01) at a concentration of 100 mg/ml. Chromatographic separation on silica gel of the ethanol extract led to the isolation of a pure organic compound which was characterized as 7-hydroxy-5,6,4'-trimethox- yflavone by extensive 1D and 2D NMR spectroscopy, a flavonoid exhibiting antioxidative activity with an inhibitory percentage of 25.506% ± 0.205% and inhibition concentration (IC<sub>50</sub>) of 221 μg/ml (R<sup>2</sup> = 0.966, P < 0.01). This is the first time that 7-hydroxy-5,6,4'-trimethoxyflavone is being isolated from L. rugosa and its antioxidant activity evaluated.
文摘发热茶为马鞭草科植物Lippia javanica(Burm.f.)Spreng.,原产于非洲中部、东部和南部,多用于治疗感冒、咳嗽、疟疾、腹泻、痢疾等疾病。采用外来中药研究方法,本文对Web of Science、PubMed、CNKI等数据库中发热茶的文献进行研究,以临床应用文献为导向,结合中医药理论对发热茶的中药药性进行理论分析。通过分析和综合归纳,将发热茶的中药药性概括为辛、苦、凉,归肺、大肠经,可疏散风热、清热燥湿、杀虫截疟,用于治疗风热感冒、湿热泻痢、虫积腹痛、疟疾寒热;外治湿疹湿疮,蜱虫。水煎服,每日用量为1~2 g;外用适量。发热茶药理作用和治病特点突出,又可内外同治,具有独特的药用价值。本文首次赋予发热茶中药药性,明确其中药性能有利于辨证施治,便于与其他中药配伍使用,为推广扩大其应用奠定基础。