In the present study we report on changes in irritable bowel syndrome-severity scoring system (IBS-SSS) and irritable bowel syndrome-quality of life (IBS-QoL) in 19 IBS patients, aged 18 to 74 years (F/M: 14/5), durin...In the present study we report on changes in irritable bowel syndrome-severity scoring system (IBS-SSS) and irritable bowel syndrome-quality of life (IBS-QoL) in 19 IBS patients, aged 18 to 74 years (F/M: 14/5), during 12 wk registering their symptoms on the web-application (www.ibs.constant-care.dk). During a control period of the first 6-wk patients were asked to register their IBS-SSS and IBS-QoL on the web-application weekly without receiving any intervention. Thereafter, low fermentable oligo-, di-, mono-saccharides and polyols (FODMAP) diet (LFD) was introduced for the next 6 wk while continuing the registration. Though a small sample size a significant improvement in disease activity (IBS-SSS) was observed during both the control period, median: 278 (range: 122-377), P = 0.02, and subsequently during the LFD period, median: 151 (range: 29-334), P < 0.01. The IBS-QoL solely changed significantly during the LFD period, median: 67 (37-120), P < 0.01. The significant reduction in disease activity during the control period shows a positive effect of the web-application on IBS symptoms when presented as a “traffic light”. However adding the diet reduced IBS-SSS to < 150, inactive to mild symptoms. In the future results from larger scale trials are awaited.展开更多
The current research of low cycle fatigue(LCF) is mainly focused on the components with uniform microstructure.Compared with these typical components, LCF behavior of welded components are more complex due to their gr...The current research of low cycle fatigue(LCF) is mainly focused on the components with uniform microstructure.Compared with these typical components, LCF behavior of welded components are more complex due to their great gradient microstructure, especially for di erent temperature. In this paper, LCF properties were conducted on the welded joint at di erent temperatures for bainite steel, and the failure mechanism was systematically discussed.Fatigue parameters derived from fitting curves indicated that welded joint had worse plastic deformation resistance and experienced more significantly strain hardening e ect at 300 °C. The joint failed in the weld metal at room temperature, which attributed to the softening in weld metal combined with cyclic strain hardening e ect in heata ected zone, which meant the joint was more sensitive with the hardness at this condition. When it came to 300 °C,more cracks appeared near to HAZ and the heterogeneous distributed surface inclusion was responsible for the fracture transition to HAZ adjacent to bainite steel rather than the softest zone in HAZ, reflecting the joint was more sensitive with the surface inclusion at 300 °C. This research could support the design on loading of welded component at di erent temperature, and further ensure the safe operation.展开更多
动态电压恢复器(dynamic voltage restorer,DVR)通过注入变压器串联接入电网与负载之间进行电压闪变抑制,其电压输出形成的直流偏磁是导致注入变压器磁饱和问题的关键,也是该类型DVR工程应用的常见难题。为保证DVR稳定运行,减少变压器...动态电压恢复器(dynamic voltage restorer,DVR)通过注入变压器串联接入电网与负载之间进行电压闪变抑制,其电压输出形成的直流偏磁是导致注入变压器磁饱和问题的关键,也是该类型DVR工程应用的常见难题。为保证DVR稳定运行,减少变压器的成本和体积,进行变压器的偏磁抑制十分必要。在分析输出变压器偏磁产生机理的基础上,提出一种利用DVR输出电压积分反馈的偏磁抑制策略,系统的幅频特性分析结果表明,该反馈的引入对原有系统并无影响。利用陷波器对积分反馈环节造成的相位偏移问题进行了补偿校正设计。在Matlab/Simulink中搭建了DVR全系统模型,并开展加入偏磁抑制策略前后的仿真分析。在电压跌落平台进行了120 kVA工业样机验证,试验结果验证了所提方法的有效性。展开更多
文摘In the present study we report on changes in irritable bowel syndrome-severity scoring system (IBS-SSS) and irritable bowel syndrome-quality of life (IBS-QoL) in 19 IBS patients, aged 18 to 74 years (F/M: 14/5), during 12 wk registering their symptoms on the web-application (www.ibs.constant-care.dk). During a control period of the first 6-wk patients were asked to register their IBS-SSS and IBS-QoL on the web-application weekly without receiving any intervention. Thereafter, low fermentable oligo-, di-, mono-saccharides and polyols (FODMAP) diet (LFD) was introduced for the next 6 wk while continuing the registration. Though a small sample size a significant improvement in disease activity (IBS-SSS) was observed during both the control period, median: 278 (range: 122-377), P = 0.02, and subsequently during the LFD period, median: 151 (range: 29-334), P < 0.01. The IBS-QoL solely changed significantly during the LFD period, median: 67 (37-120), P < 0.01. The significant reduction in disease activity during the control period shows a positive effect of the web-application on IBS symptoms when presented as a “traffic light”. However adding the diet reduced IBS-SSS to < 150, inactive to mild symptoms. In the future results from larger scale trials are awaited.
基金Supported by National Natural Science Foundation of China(Grant Nos.51675336,U1660101,and 51775338)
文摘The current research of low cycle fatigue(LCF) is mainly focused on the components with uniform microstructure.Compared with these typical components, LCF behavior of welded components are more complex due to their great gradient microstructure, especially for di erent temperature. In this paper, LCF properties were conducted on the welded joint at di erent temperatures for bainite steel, and the failure mechanism was systematically discussed.Fatigue parameters derived from fitting curves indicated that welded joint had worse plastic deformation resistance and experienced more significantly strain hardening e ect at 300 °C. The joint failed in the weld metal at room temperature, which attributed to the softening in weld metal combined with cyclic strain hardening e ect in heata ected zone, which meant the joint was more sensitive with the hardness at this condition. When it came to 300 °C,more cracks appeared near to HAZ and the heterogeneous distributed surface inclusion was responsible for the fracture transition to HAZ adjacent to bainite steel rather than the softest zone in HAZ, reflecting the joint was more sensitive with the surface inclusion at 300 °C. This research could support the design on loading of welded component at di erent temperature, and further ensure the safe operation.
文摘动态电压恢复器(dynamic voltage restorer,DVR)通过注入变压器串联接入电网与负载之间进行电压闪变抑制,其电压输出形成的直流偏磁是导致注入变压器磁饱和问题的关键,也是该类型DVR工程应用的常见难题。为保证DVR稳定运行,减少变压器的成本和体积,进行变压器的偏磁抑制十分必要。在分析输出变压器偏磁产生机理的基础上,提出一种利用DVR输出电压积分反馈的偏磁抑制策略,系统的幅频特性分析结果表明,该反馈的引入对原有系统并无影响。利用陷波器对积分反馈环节造成的相位偏移问题进行了补偿校正设计。在Matlab/Simulink中搭建了DVR全系统模型,并开展加入偏磁抑制策略前后的仿真分析。在电压跌落平台进行了120 kVA工业样机验证,试验结果验证了所提方法的有效性。
