Changes and Correlations of Duroc Muscle pH,Glycogen,Lactic Acid and TBA under Different Storage Condition

The changes and correlations of muscle pH, glycogen, lactic acid and in- tramuscular fat oxidation in Duroc pigs 10 d after their slaughter, and the effects of different storage temperature and time on Duroc muscle pH value, water loss rate, glycogen, lactic acid and 2-thiobarbituric acid （TBA） were studied. The results showed that during the 10 h after the slaughter, the pH value was decreased rapid- ly, the lactic acid content was increased significantly, while the glycogen and TBA contents were remained stable. At the storage temperature of 4 ℃, storage time showed no significant effects on Duroc muscle pH value and glycogen, lactic acid and TBA contents. At the storage temperature of -20 ℃, storage temperature had significant effects on pH value, while no significant effects on other indicators. The correlation analysis demonstrated that during the 10 h after the slaughter, the TBA content was negatively related to glycogen content （P〈0.05）, but positively related to lactic content （P〈0.05）; the pH value was negatively related to lactic acid content （P〈0.05）. At the storage temperature of 4 ℃, the TBA content was negatively relat- ed to water loss rate （P〈0.01） and lactic acid content （P〈0.05）; the water loss rate was positively related to pH value （P〈0.01） and lactic acid content （P〈0.05）. At the storage temperature of -20 ℃, the TBA content was negatively related to pH value （P〈0.01） and positively related to water loss rate （P〈0.05）; the water loss rate was negatively related to pH value （P〈0.01） and lactic acid content （P〈0.05）.

Study of the immunoisolating effects of barium-alginate microencapsu lation on rat islets allograft survival

Objective: To evaluate the immunoisola ti ng effects of barium-alginate microencapsulation on islets allograft survival. Methods: The nonmicroencapsulated and microencapsulated islets w ere transplanted under the kidney capsule or intraperitoneally into Wistar rat w ith STZ-induced diabetes. The blood glucose and insulin secretion of grafts wer e observed. Graft function was tested by oral glucose tolerance test (OGTT). Results: ①Five diabetic rats became normoglycemic for 48 to 72 h after microencapsulated islets transplantation. The survival of transplanted i slets was on an average of 6 W. ②The normalization of the glycemia and insulin in the transplanted rats was associated with normal glucose and insulin profiles in response to OGTT. Conclusion: Microencapsulation with barium -alginate membrane can prolong islet survival and protect islets against allore jection.

Design of an Integrated SITL and HITL Simulation System for the Control of a Loitering Aerial Vehicle

An investigation into the aircraft flight simulation and control system is presented in this paper. The study was firstly focused on the establishment of an integrated hardware-in-the-loop（HITL） platform for aircraft flight simulation based on MATLAB/Simulink ＋ dSPACE. The platform combines the abundant software and hardware resources of dSPACE simulation platform to simulate the flight attitude of an aircraft in six-DOF （ degree of freedom） motion. Based on the platform, the study was then focused on the flight numerical simulation by taking a loitering aerial vehicle as an example. An aircraft mathematical model was created for a modular design and off-line numerical simulation based on MATLAB/Simulink. Finally, the study was focused on the control system design of the loitering aerial vehicle and conduct of an HITL simulation experiment for the vehicle pitch control. The experiment verifies the system design and control effectiveness. Research results show that the dSPACE simulation system provides a real time good experimental platform to improve the efficiency of study and development of a flight control system.

基于Plant Simulation软件的地铁车辆车体生产产能分析

车体作为车辆的重要组成部分,提高车体产能是工厂日益迫切需要解决的问题.运用Plant Simulation仿真软件建立车体生产线模型,对生产过程进行仿真计算,识别瓶颈工序,提出解决方法.对关键设备的利用率进行计算,进行相应产能优化.结果表明,优化后的车体生产产能可以提升33.33%.

Structure Analysis for Hydrate Models of Ethyleneimine Oligomer by Quantum Chemical Calculation

Structure analyses for hydrate models of ethyleneimine oligomer (5-mer as model of PEI) were investigated by quantum chemical calculations. Conformation energies and structures optimized for hydrate models of (ttt)5 and (tgt)5 conformers were examined. Hydrate ratio, h [h = H2O/N (mol)], was set from 0.5 to 2. In anhydrates, (tg+t)5 conformer was more stable (?1.8 kcal/m.u.) than (ttt)5. In hydrates, (ttt)5 conformers were more stable (?0.7 - ?4.3) than (tg+t)5. These results corresponded to experimental results that anhydrous linear PEI crystal changes from double helical to single planar chain in hydration process. Structures calculated for (ttt)5 agreed in those observed for hydrates of PEI. In all (tg+t)5 conformers, O???H bonds between waters were found with the decreases of N???H bonds between imino group and water. The O???H bonds in (tg+t)5 conformer resulted in its high chain torsion, and strongly related with instability and structure change (large swelling).

HPLCASSAY FOR INTRACELLULAR ACCUMULATION OF VERAPAMIL IN VER-RESISTANT HUMAN LEUKEMIC CELL SUSLINES AND THEIR PARENTAL CELL LINES

Objective: To establish a HPLC method using fluorometric detection for quantitatively determinating intracellular accumulation of verapamil (VER). Methods: Chromatography column was packed with spherisorb ODS(250×4.6 mm,10 μm).The mobile phase consisted of the mixture of methanol:NaAC (0.01 mol/L): diethylamine (65:35:0.25). The detect wavelength was 280/310 nm (Ex/Em). Results: The standard curve showed a good correlation between concentration and peak area within the range of 5-50 ng/ml. RSD was 0.86%, and recovery radio of loading sample, 100%. The detection limit for cell sample was 0.2-148 ng/ml. Intracellular accumulation of VER was observed to decrease from a 13 fold to 5 fold in K562/ADM cells, and from a 3.5 fold to 4.3 fold in K562/VER cells and from a 2.1 fold to 6.5 fold in K562/ADM/VER cells, compared with the relevant control cells. Conclusion: HPLC method was proved to be sensitive and specific for using to quantitatively determine the intracellular accumulation of VER.

Modifications of Norditerpenoid Alkaloids: Ⅰ.N-Deethylation Reactions

Using oxidation with KMnO4. KMnO4/acetone-H2O. NAS. followed by Polonovskyreaction and imine formation. the N-deethylation of six norditerpenoid alkaloids 6-epi-forsticille.yunnaconitine. 3. 13-diacetylyunnaconitine. 13-dehydroxy-indaconitine. indaconitine and 3-acetylpseudaconine are reported in 36-60% yields.

Genetic algorithm for λ-optimal translation sequence of rough communication

In rough communication, because each agent has a different language and can not provide precise communication to each other, the concept translated among multi-agents will loss some information, and this results in a less or rougher concept. With different translation sequences the amount of the missed knowledge is varied. The λ-optimal translation sequence of rough communication, which concerns both every agent and the last agent taking part in rough communication to get information as much as he （or she） can, is given. In order to get the λ-optimal translation sequence, a genetic algorithm is used. Analysis and simulation of the algorithm demonstrate the effectiveness of the approach.

Vacuum Insulation and Achievement of 980 keV,185 A/m^2 H-Ion Beam Acceleration at JAEA for the ITER Neutral Beam Injector

Abstract Vacuum insulation of -1 MV is a common issue for the HV bushing and the accel- erator for the ITER neutral beam injector （NBI）. The HV bushing as an insulating feedthrough has a five-stage structure and each stage consists of double-layered insulators. To sustain -1 MV in vacuum, reduction of electric field at several triple points existing around the double-layered insulators is a critical issue. To reduce electric field simultaneously at these points, three types of stress ring have been developed. In a voltage holding test of a full-scale mockup equipped with these stress rings, 120% of rated voltage was sustained and the voltage holding capability required in ITER was verified. In the MeV accelerator, whose target is the acceleration of a H- ion beam of 1 MeV, 200 A/mS, the gap between the grid support was extended to suppress breakdowns triggered by electric field concentration at the edge and corner of the grid support. This modi- fication improved the voltage holding capability in vacuum, and the MeV accelerator succeeded in sustaining -1 MV stably, b-~rthermore, it appeared that the H- ions beam was deflected and a part of the beam was intercepted at the acceleration grid, This causes high heat load on the grids and breakdowns during beam acceleration. To suppress the direct interception, a new grid was designed with proper aperture displacement based on a three dimensional beam trajectory analysis, As a result, 980 keV, 185 A/ms H- ion beam acceleration has been demonstrated, which is close to the ITER requirement.

术语翻译与使用——论蒯因术语“Radical Translation”之译名

术语及其翻译是同一个所指的不同能指,多个能指出现会导致学术研究基础不牢、精密性缺失、术语污染和理解堵车现象,这不仅关乎哲学术语界的纯净,也是所有术语工作者会遇到的难题。论文以美国著名哲学家、逻辑学家蒯因提出的术语"radical translation"为例,基于中国知网期刊数据,回归原文,查阅并总结前人译法,一并考虑其派生术语"radical interpretation",再运用术语使用的"广泛"、"约定俗成性"和术语翻译的"准确性"、"经济性",分析"radical translation"已有部分译名,指出其优劣,综合考虑后得出"radical translation"应译为"彻底翻译"的结论。术语是学术的基础,其翻译及使用应引起高度重视。

Quantum Chemical Calculation on Preparation of YBa＿2Cu＿3O＿（7－δ） Powders by Hydrolysis of Metal Alkoxides

The structural characteristics of different alkoxides of Y. Ba and Cu are studied with quantum chemi-cal CNDO /2 calculations. The relative hydrolysis rate coefficients k_M of them are obtained according tothe relationship between frontier orbitals and organic chemical reactions. Based on the above results. properexperimental conditions for the preparation of homogeneous ultra-purity. submicro high-T_cYBa_2Cu_3O_(7-δ) superconducting powders are proposed.

COEXISTENCE OF FOS-LIKE PROTEIN IN TYROSINE HYDROXYLASE-LIKE IMMUNOREACTIVE NEURONS IN THE HINDBRAIN OF ARTS FOLLOWING PERIPHERAL ELECTRICAL STIMULATION

In the present study we have found that proto-oncogene c-fos protein can expressin the noradrenergic neurons of rat hindbrain following peripheral electrical stimulation. Ratswere given peripheral electrical stimulation via thin stainless steel pins inserted into the pointsnear knee joint (S36) and ankle joint (Sp6) which mimic the manipulation of electroacupuncture(EA) performed in humans. Animals were perfused for double staining immunohistochemistry 2hafter the termination of EA. In rats subjected to EA stimulation Fos-like protein was found in thetyrosine hydroxylase (TH)-like immunoreactive neurons in rat hindbrain. The Fos and TH coex-isting neurons were distributed in the locus coeruleus, solitary tract nucleus, ventrolateral medul-la, periaqeductal gray, as well as superior colliculus. The percentage of the coexisting neuronscompared with the total number of neurons containing Fos-like protein in these nuclei rangedfrom 6% to 32%. The results suggest that the noradrenergic neurons in these regions may be ac-tivted by acupuncture stimulation.

融合裂缝形态信息的电阻率测井成像图空白条带填充方法

电阻率测井成像图中存在宽度和位置不定的空白条带,而目前常用的空白条带反距离加权插值填充法仅依靠像素点距离参数计算插值,往往导致填充后区域与实测区域纹理不连贯,纹理易呈现直线状,与实际状况不符。为此,将裂缝区域形态与分布信息作为参量,构建插值计算模型,形成融合裂缝形态分布信息的空白条带填充法。该填充算法能根据插值点与裂缝形态拟合线的相对位置关系,动态调整参考点对插值点插值的权重系数,填充后的裂缝区域纹理连贯平滑,更符合裂缝实际形态和分布的规律。实际测井数据应用表明,相较于传统填充方法,采用该方法填充后的裂缝分布拟合线与霍夫变换后曲线相似度提升25%以上,不连贯填充点数量下降88%以上,性能提升明显。该方法的应用成果可为后续测井图像中各种裂缝的智能识别和精确分割提供更好的数据支撑。

基于SERVQUAL模型的水上娱乐设施设计研究

目的 由于水上娱乐设施具有普适性,而各景区气候、地形、水系和发展重点不同,本文以木兰天池水上娱乐设施为例,旨在为其提出设计优化策略并对其进行设计研究。方法 首先,提取自然环境要素因子和娱乐设施要素因子,得出综合要素因子分类,即人员服务、设施服务、设施安全;其次,以SERVQUAL模型的五个维度为基准,构建出服务评价量表并采用选项隶属度计算进行筛选,得出最终服务评价量表;随后运用调查问卷、信度效度分析、因子分析;最后,计算出各指标感知与期望的差值。结果 舒适度、分流分区、环境安全、材料材质安全、结构安全、维护维修是木兰天池景区水上娱乐设施的主要设计要素,以此进行木兰天池景区水上娱乐设施设计研究。结论 此方法为设计景区同类水上娱乐设施提供了理论依据。

二代冷冻球囊治疗心房颤动合并高血压的安全性和有效性研究

目的本研究旨在回顾性分析二代冷冻球囊导管治疗心房颤动合并高血压的有效性和安全性。方法选择在福建省立医院接受二代球囊冷冻消融手术的1027例房颤患者,回顾性分析两组基线资料、术中参数及并发症发生情况。利用Kaplan-Meier法计算术后12个月、24个月及36个月两组房颤患者无房扑/房颤发生的概率。结果高血压组与非高血压组在合并糖尿病、冠心病、BMI、年龄、左房大小、CHA2DS2-VASC评分、HAS-BLED评分差异有统计学意义(P>0.05);两组术中参数差异无统计学意义;围手术期主要并发症相似(3.3%vs.3.0%,P=1),两组术后12个月、24个月及36个月的成功率分别为:82.0%vs.81.2%;74.9%vs.72.9%;66.3%vs.72.9%。生存曲线差异无统计学意义(95%CI:0.75,1.4,P=0.23)。结论二代冷冻球囊肺静脉电隔离PVI治疗房颤合并高血压与治疗非高血压一样,有良好的安全性和成功率。

黄芪桂枝五物汤加味联合中频脉冲电刺激治疗糖尿病合并脑卒中偏瘫的临床研究

目的探讨黄芪桂枝五物汤加味联合中频脉冲电刺激治疗糖尿病合并脑卒中偏瘫的临床疗效。方法选取2019年4月—2022年3月河北北方学院附属第一医院康复科及内分泌科老年糖尿病合并脑卒中偏瘫患者120例,依据随机表分为对照组60例和治疗组60例,对照组给予中频脉冲电刺激加常规康复运动疗法,治疗组在对照组基础上给予黄芪桂枝五物汤加味治疗,比较两组患者治疗前后血糖水平、运动神经电生理指标[运动诱发电位潜伏期(motor evoked potentials,MEP)、中枢运动传导时间(central motor conduction time,CMCT)]、运动功能[Fugl-Meyer运动功能评分(Fugl-Meyer Assessment,FMA)]、生活质量及神经功能相关评分[脑卒中专用生活质量量表(Stroke Specific Quality of Life Scale,SS-QOL)、改良Barthel指数(modified Barthel Index,MBI)、美国国立卫生研究所卒中评分量表(National Institutes of Health Stroke Scale,NIHSS)、临床神经功能缺损评分(China Stroke Scale,CSS)量表、抑郁自评量表(Self-Rating Depression Scale,SDS)]。结果(1)血糖水平:治疗12周后,治疗组和对照组空腹血糖和餐后血糖均有所下降,降血糖效果明显;与对照组比较,治疗组血糖水平下降幅度更大(P<0.05)。(2)运动神经电生理指标:两组各项指标(MEP、CMCT)较治疗前均明显降低(P<0.05),且治疗组与对照组比较,治疗组降低幅度更大(P<0.05)。(3)上肢、下肢FMA评分:治疗12周后,对照组和治疗组评分均有明显升高,且治疗组分值提升显著高于对照组(P<0.05)。(4)生活质量评分:治疗后,对照组和治疗组各项评分(SS-QOL、MBI)均明显高于治疗前,且治疗组得分上升幅度显著优于对照组(P<0.05)。(5)神经功能评分:治疗后,两组各项评分(NIHSS、CSS、SDS)均有明显降低(P<0.05),且治疗组比对照组各项评分降低幅度更为显著(P<0.05)。结论黄芪桂枝五物汤加味联合中频脉冲电刺激可有效治疗糖尿病合并脑卒中偏瘫患者的运动功能,有利于改善生活质量,值得临床推广。

数智时代的互联网平台企业:治理与规制

互联网平台企业掌握的海量大数据和智能算法的技术优势,使其在以数据和算法为主要支撑的数智时代的影响力和控制力日渐增强。面对日渐强势的互联网平台企业,在积极推动其参与国家治理、推进国家治理体系和治理能力现代化的同时,也需要各国在法律和技术层面强化对互联网平台企业日常经营和技术研发活动的规制,并构建有效的全球治理体系和完善相应的全球治理机制来应对互联网平台企业及其背后的资本对全球治理秩序的冲击。

Simple estimation of electron correlation energy for multi-atomic strong ionic compounds KX and (KX)_2 (X=OH, NC)

On the basis of the calculations and analyses of the intrapair and interpair correlation energy of KX (X = OH, NC) molecules and the results of the transferability of both the innermost intrapair correlation energy and the inner core effect of K and X in KX molecules, we defined and calculated the Kδ- and Xδ-correlation contributions to the total correlation energy of KX molecules. With the comparison of the pair correlation energy of K+, X- and KX systems, we present a simple estimation method to estimate the electron correlation energy of strong ionic compound by summarizing the correlation energy of its constituent ion and ionic group. By using this simple method, the reasonable estimation results of the correlation energy of (KOH)2 and (KNC)2 have been obtained at mp2/6-311++G(d) level with Gaussian98 program, and the deviations are very small. Applying the scheme of 'Separate Large System into Smaller Ones' to the calculation of electron correlation energy of large ionic compounds, it can not only save lot of computation work but also reach the chemical accuracy.

退火工艺对LaTiON和HfLaON存储层金属-氧化物-氮化物-氧化物-硅存储器特性的影响

采用反应溅射法,分别制备以LaTiON,HfLaON为存储层的金属-氧化物-氮化物-氧化物-硅电容存储器,研究了淀积后退火气氛(N2,NH3)对其存储性能的影响.分析测试表明,退火前LaTiON样品比HfLaON样品具有更好的电荷保持特性,但后者具有更大的存储窗口(编程/擦除电压为+/12V时4.8V);对于退火样品,由于NH3的氮化作用,NH3退火样品比N2退火样品表现出更快的编程/擦除速度、更好的电荷保持特性和疲劳特性.当编程/擦除电压为+/-12V时,NH3退火HfLaON样品的存储窗口为3.8V,且比NH3退火LaTiON样品具有更好的电荷保持特性和疲劳特性.

基于改进虚拟同步发电机控制的功率交互振荡抑制策略

在指令功率发生扰动时,虚拟同步发电机控制环路易产生功率交互振荡,威胁系统的安全稳定运行。为此,提出一种基于改进虚拟同步发电机控制的功率交互振荡抑制策略。基于相对增益矩阵原理研究不同系统参数变化时虚拟同步发电机输出功率间交互作用的变化规律;采用转速阻尼功率高通反馈改进虚拟同步发电机有功功率-频率控制环路,并通过绘制Bode图对比传统虚拟同步发电机控制策略与改进虚拟同步发电机控制策略的暂态和稳态性能;利用相对增益矩阵原理分析改进虚拟同步发电机控制策略的有功功率环路交互作用情况。仿真及实验结果表明,所提策略可有效实现虚拟同步发电机交互振荡的抑制。