Objective:To investigate the anxiolytic activity of newly isolated compound by our lab called ursolic acid stearoyl glucoside(UASG) from the leaves of Lantana camam(L camam).Methods: Column chromatography was used to ...Objective:To investigate the anxiolytic activity of newly isolated compound by our lab called ursolic acid stearoyl glucoside(UASG) from the leaves of Lantana camam(L camam).Methods: Column chromatography was used to isolate UASG.Anxiolytic potential was experimentally proved and demonstrated through Elevated plus-maze,Open field and light and dark test. Results:The UASG showed marked increased in time spent(%) and number of frequent movements made by animals in open arm of elevated plus-maze apparatus.In light and dark model,UASG produced marked increase in time spent by animal,number of crossing and reduced duration of immobility in light box.Conclusions:UASG showed significant increase in number of rearing,assisted rearing and number of square crossed in open field established test model.UASG showed its anxiolytic effect in dose dependent manner.展开更多
Objective:To investigate the toxicity of methanol extract of various parts(Root,Stem,Leaf, Flower and Fruit) of Lantana camara(L.Camara) in Artemia salina.Methods:The methanol extracts of L.camara were tested for in v...Objective:To investigate the toxicity of methanol extract of various parts(Root,Stem,Leaf, Flower and Fruit) of Lantana camara(L.Camara) in Artemia salina.Methods:The methanol extracts of L.camara were tested for in vivo brine shrimp lethality assay.Results:All the tested extract exhibited very low toxicity on brine shrimp larva.The results showed that the root extract was the most toxic part of L.camara and may have potential as anticancer agent.Conclusions: Methanolic extract of L.camara is relatively safe on short-term exposure.展开更多
Objective:To investigate the antioxidant activity of methanolic extracts of Lantana camara(L.camara)various parts and the determination of their total phenolics content.Methods:The extract was screened for possible an...Objective:To investigate the antioxidant activity of methanolic extracts of Lantana camara(L.camara)various parts and the determination of their total phenolics content.Methods:The extract was screened for possible antioxidant activities by free radicaI scavenging activity(DPPH),xanthine oxidase inhibition activity and Griess—llosvay method。Results:The results showed that all the plant parts possessed antioxidant properties including radical scavenging,xanthine oxidase ildfibition and nitrites seavenging activities.The antioxidative activities were correlated with the total phenol.The leaves extract of L.camara was more effective than that of other parts.Conclusions:This study suggests that L.camara extracts exhibit great potential for antioxidant activity and may be useful for their nutdtional and medicinal functions.展开更多
Objective:To synthesize the silver nunoparticles(AgNPs) by reduction of silver ions into nano silver,using ripened berry extract of Lantana camara and evaluate its antioxidant activity against 1.1-diphenyl-2- picrylhy...Objective:To synthesize the silver nunoparticles(AgNPs) by reduction of silver ions into nano silver,using ripened berry extract of Lantana camara and evaluate its antioxidant activity against 1.1-diphenyl-2- picrylhydrazyl.Methods:The prepared AgNPs were characterized by visual,UV-visible spectrophotometer.dynamic light scattering and transmission electron microscopy with selected area electron diffraction.Results:Transmission electron microscopy and dynamic light scattering analysis confirmed the AgNPs are spherical and 75.2 nm average sized.Selected area electron diffraction analysis supports that the obtained nanoparticles were in crystalline form.In addition,the antioxidant efficacy of prepared AgNPs was found to be higher than berry extract against 1.1-diphenyl-2-picrylhydrazyl.Conclusions:From the results obtained it is suggested that surface modified AgNPs at lower concentration,showed higher antioxidant activity than berry extract against 1,1-diphenyl-2-picrylhydrazyl and could be used effectively in future ethno pharmacological concerns.展开更多
This study investigated the adsorption of Methylene Blue (MB) present in wastewater onto the activated carbon produce from Lantana camara stem. The agricultural material (Lantana camara stem) was carbonized at 300...This study investigated the adsorption of Methylene Blue (MB) present in wastewater onto the activated carbon produce from Lantana camara stem. The agricultural material (Lantana camara stem) was carbonized at 300°C for 2 h, ground and steam-activated. The Steam-Activated Lantana camara (SALC) stem carbon was characterized using Scanning Electron Microscope (SEM) and Fourier Transform Infrared (FTIR) Spectrophotometry before and after adsorption. Batch model experiments were conducted at 20°C to study the effects of pH, agitation time, adsorbent dosage and initial concentration of methylene blue. The equilibrium adsorption isotherms and kinetics were investigated. The FTIR bands at 3500, 2500, 2196 and 1682 cm-1 were shifted to 3646.3, 3030, 2822, 1709.05 cm-1 after MB adsorption. Similarly, the Scanning Electron Microscopy (SEM) analysis showed that the average pore size on the activated carbon was 20 μm. The Methylene Blue (MB) uptake increased with the increase in pH. Similarly, the dye adsorption increased as contact time increased, and reached equilibrium at 60 minutes. The removal of the dye increased when the dosage was increased from 0.5 - 2.0 g·L-1, at different dye concentrations (50 - 200 mg·L-1). The percentage removal decreased with increasing initial dye concentration for SALC. The adsorption isotherm data fitted well to the Freundlich isotherm (R2 = 0.989) while the experimental data fitted very well to the pseudo-second-order kinetic model (R2 = 0.99). This study suggests that adsorbent prepared from Lantana camara stem can be used effectively for the adsorption of methylene blue in wastewater.展开更多
Viburnum lantana L.(Caprifoliaceae)is a shrub up to 3-5 m tall,with red or black drupes.Researchers have studied the chemical composition of different parts of the plant and found many compounds with novel structures,...Viburnum lantana L.(Caprifoliaceae)is a shrub up to 3-5 m tall,with red or black drupes.Researchers have studied the chemical composition of different parts of the plant and found many compounds with novel structures,including chalcone glycosides,iridoid glycosides,and some terpenoids.At the same time,it has been reported that the extracts from different parts of V.lantana have a variety of biological activities,including antioxidant,antimicrobial,and AChE Inhibitory activities.This study reviewed the chemical components and bioactivities of the V.lantana reported in recent years.展开更多
Two compounds with different bioactivities were isolated from the leaves of the Lantana camara Linn plant.Compound 1 was triterpenoid(Lantadene B)(22β-dimethylacroyloxy-3-oxoolean-12-en-28-oic-acid,C_(35)H_(52)O_5),w...Two compounds with different bioactivities were isolated from the leaves of the Lantana camara Linn plant.Compound 1 was triterpenoid(Lantadene B)(22β-dimethylacroyloxy-3-oxoolean-12-en-28-oic-acid,C_(35)H_(52)O_5),which was isolated from n-hexane fraction and obtained as white solid(amorphous).Compound 2 was glycoside flavonoid(5-hydroxy-6,4′-dimethoxy flavon-7-O-glucopyranose,C_(23)H_(24)O_(11)),which was isolated from ethyl acetate and obtained as pale yellow solid(amorphous).Extraction was performed with maceration method using methanol solvent.Subsequently,fractionation was carried out using n-hexane and ethyl acetate solvents.Isolation and purification of both fractions were conducted using chromatography method.The structure of the isolated compounds was determined through spectral analyses of ultraviolet(UV),infrared(IR),and nuclear magnetic resonance(~1H NMR and ^(13)C NMR),distortionless enhancement by polarization transfer(DEPT),heteronuclear multiple bond connectivity(HMBC),heteronuclear single quantum correlation(HSQC),and H-H COSY(~1H-~1H homonuclear correlated spectroscopy).The cytotoxic activity of compound 1 was tested against MCF-7 breast cancer cells in vitro using MTT assay(3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide),showing very strong cytotoxic activity in inhibiting the growth of MCF-7 breast cancer cells,and the IC_(50) value was 1.1336μM.The antioxidant activity of compound 2 was tested using DPPHassay(1,1-diphenyl-2-picrylhydrazyl),showing strong activity in inhibiting free radicals,and its IC_(50) value was 71.03 mg/L.展开更多
Background:The aim of this study is to elucidate the potential risk zones prone to the invasion of perennial ornamental plant Lantana camara,which is native to South America and has invasive tendency in Jharkhand,east...Background:The aim of this study is to elucidate the potential risk zones prone to the invasion of perennial ornamental plant Lantana camara,which is native to South America and has invasive tendency in Jharkhand,eastern India,for present(2020)and the future(2050)climatic conditions under four different Representative Concentration Pathways scenarios(RCPs).We analysed the current distribution pattern of L.camara in the plateau region of eastern India and identified potentially suitable habitats prone to its further infestation in the future under the climate change scenario.Results:Results showed the presence of L.camara invasion in~13%of the geographical area of Jharkhand,Cho-tanagpur plateau which may expand up to 20–26%by 2050 depending upon emission scenarios as characterised by the four RCPs.Analysis for the current scenario suggests the dominance of L.camara in sub-zone V(12.77%under high risk zones(HRZ)and 9.5%under critical risk zones(CRZ))followed by sub-zones IV(6.7%:HRZ;4.19%:CRZ)and VI(2.49%:HRZ;2.14%:CRZ).Future projection(2050)indicates a possible expansion of its distribution range across all agro-climatic sub-zones with dominance in sub-zones V and IV.Variable Bio_4(temperature seasonality)was observed as the most contributing factor for the distribution of L.camara for current and future scenarios across all RCPs.Suitable habitat for L.camara mostly occurred under natural vegetation(66.05%of CRZ and 60.71%of HRZ)and agriculture landscape(29.51%of CRZ and 34.48%of HRZ).Conclusions:The study provides an insight of invasion of L.camara in the plateau region of eastern India,and reveals wide distribution across all the agro-climatic sub-zones of Jharkhand,mostly in open and disturbed areas under natural vegetation and agriculture landscapes.Future projections for the year 2050 suggest a continuous increase in the expansion range of invasion across Jharkhand and call for urgent initiatives to combat its further invasion.展开更多
文摘Objective:To investigate the anxiolytic activity of newly isolated compound by our lab called ursolic acid stearoyl glucoside(UASG) from the leaves of Lantana camam(L camam).Methods: Column chromatography was used to isolate UASG.Anxiolytic potential was experimentally proved and demonstrated through Elevated plus-maze,Open field and light and dark test. Results:The UASG showed marked increased in time spent(%) and number of frequent movements made by animals in open arm of elevated plus-maze apparatus.In light and dark model,UASG produced marked increase in time spent by animal,number of crossing and reduced duration of immobility in light box.Conclusions:UASG showed significant increase in number of rearing,assisted rearing and number of square crossed in open field established test model.UASG showed its anxiolytic effect in dose dependent manner.
基金Supported by a grant form Universiti Sains Malaysia University
文摘Objective:To investigate the toxicity of methanol extract of various parts(Root,Stem,Leaf, Flower and Fruit) of Lantana camara(L.Camara) in Artemia salina.Methods:The methanol extracts of L.camara were tested for in vivo brine shrimp lethality assay.Results:All the tested extract exhibited very low toxicity on brine shrimp larva.The results showed that the root extract was the most toxic part of L.camara and may have potential as anticancer agent.Conclusions: Methanolic extract of L.camara is relatively safe on short-term exposure.
基金supported by USM Incentive Grant(Grant Number:2009/167)From Universiti Sains Malaysia
文摘Objective:To investigate the antioxidant activity of methanolic extracts of Lantana camara(L.camara)various parts and the determination of their total phenolics content.Methods:The extract was screened for possible antioxidant activities by free radicaI scavenging activity(DPPH),xanthine oxidase inhibition activity and Griess—llosvay method。Results:The results showed that all the plant parts possessed antioxidant properties including radical scavenging,xanthine oxidase ildfibition and nitrites seavenging activities.The antioxidative activities were correlated with the total phenol.The leaves extract of L.camara was more effective than that of other parts.Conclusions:This study suggests that L.camara extracts exhibit great potential for antioxidant activity and may be useful for their nutdtional and medicinal functions.
基金Supported by the Prometeo Project of the National Secretary of Higher Education.Science.Technology and Innovation,Ecuador
文摘Objective:To synthesize the silver nunoparticles(AgNPs) by reduction of silver ions into nano silver,using ripened berry extract of Lantana camara and evaluate its antioxidant activity against 1.1-diphenyl-2- picrylhydrazyl.Methods:The prepared AgNPs were characterized by visual,UV-visible spectrophotometer.dynamic light scattering and transmission electron microscopy with selected area electron diffraction.Results:Transmission electron microscopy and dynamic light scattering analysis confirmed the AgNPs are spherical and 75.2 nm average sized.Selected area electron diffraction analysis supports that the obtained nanoparticles were in crystalline form.In addition,the antioxidant efficacy of prepared AgNPs was found to be higher than berry extract against 1.1-diphenyl-2-picrylhydrazyl.Conclusions:From the results obtained it is suggested that surface modified AgNPs at lower concentration,showed higher antioxidant activity than berry extract against 1,1-diphenyl-2-picrylhydrazyl and could be used effectively in future ethno pharmacological concerns.
文摘This study investigated the adsorption of Methylene Blue (MB) present in wastewater onto the activated carbon produce from Lantana camara stem. The agricultural material (Lantana camara stem) was carbonized at 300°C for 2 h, ground and steam-activated. The Steam-Activated Lantana camara (SALC) stem carbon was characterized using Scanning Electron Microscope (SEM) and Fourier Transform Infrared (FTIR) Spectrophotometry before and after adsorption. Batch model experiments were conducted at 20°C to study the effects of pH, agitation time, adsorbent dosage and initial concentration of methylene blue. The equilibrium adsorption isotherms and kinetics were investigated. The FTIR bands at 3500, 2500, 2196 and 1682 cm-1 were shifted to 3646.3, 3030, 2822, 1709.05 cm-1 after MB adsorption. Similarly, the Scanning Electron Microscopy (SEM) analysis showed that the average pore size on the activated carbon was 20 μm. The Methylene Blue (MB) uptake increased with the increase in pH. Similarly, the dye adsorption increased as contact time increased, and reached equilibrium at 60 minutes. The removal of the dye increased when the dosage was increased from 0.5 - 2.0 g·L-1, at different dye concentrations (50 - 200 mg·L-1). The percentage removal decreased with increasing initial dye concentration for SALC. The adsorption isotherm data fitted well to the Freundlich isotherm (R2 = 0.989) while the experimental data fitted very well to the pseudo-second-order kinetic model (R2 = 0.99). This study suggests that adsorbent prepared from Lantana camara stem can be used effectively for the adsorption of methylene blue in wastewater.
文摘Viburnum lantana L.(Caprifoliaceae)is a shrub up to 3-5 m tall,with red or black drupes.Researchers have studied the chemical composition of different parts of the plant and found many compounds with novel structures,including chalcone glycosides,iridoid glycosides,and some terpenoids.At the same time,it has been reported that the extracts from different parts of V.lantana have a variety of biological activities,including antioxidant,antimicrobial,and AChE Inhibitory activities.This study reviewed the chemical components and bioactivities of the V.lantana reported in recent years.
文摘Two compounds with different bioactivities were isolated from the leaves of the Lantana camara Linn plant.Compound 1 was triterpenoid(Lantadene B)(22β-dimethylacroyloxy-3-oxoolean-12-en-28-oic-acid,C_(35)H_(52)O_5),which was isolated from n-hexane fraction and obtained as white solid(amorphous).Compound 2 was glycoside flavonoid(5-hydroxy-6,4′-dimethoxy flavon-7-O-glucopyranose,C_(23)H_(24)O_(11)),which was isolated from ethyl acetate and obtained as pale yellow solid(amorphous).Extraction was performed with maceration method using methanol solvent.Subsequently,fractionation was carried out using n-hexane and ethyl acetate solvents.Isolation and purification of both fractions were conducted using chromatography method.The structure of the isolated compounds was determined through spectral analyses of ultraviolet(UV),infrared(IR),and nuclear magnetic resonance(~1H NMR and ^(13)C NMR),distortionless enhancement by polarization transfer(DEPT),heteronuclear multiple bond connectivity(HMBC),heteronuclear single quantum correlation(HSQC),and H-H COSY(~1H-~1H homonuclear correlated spectroscopy).The cytotoxic activity of compound 1 was tested against MCF-7 breast cancer cells in vitro using MTT assay(3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide),showing very strong cytotoxic activity in inhibiting the growth of MCF-7 breast cancer cells,and the IC_(50) value was 1.1336μM.The antioxidant activity of compound 2 was tested using DPPHassay(1,1-diphenyl-2-picrylhydrazyl),showing strong activity in inhibiting free radicals,and its IC_(50) value was 71.03 mg/L.
基金funding for the project(IFP-083/A&Extn-02/2016-2019)was provided by ICFRE,Dehradun.
文摘Background:The aim of this study is to elucidate the potential risk zones prone to the invasion of perennial ornamental plant Lantana camara,which is native to South America and has invasive tendency in Jharkhand,eastern India,for present(2020)and the future(2050)climatic conditions under four different Representative Concentration Pathways scenarios(RCPs).We analysed the current distribution pattern of L.camara in the plateau region of eastern India and identified potentially suitable habitats prone to its further infestation in the future under the climate change scenario.Results:Results showed the presence of L.camara invasion in~13%of the geographical area of Jharkhand,Cho-tanagpur plateau which may expand up to 20–26%by 2050 depending upon emission scenarios as characterised by the four RCPs.Analysis for the current scenario suggests the dominance of L.camara in sub-zone V(12.77%under high risk zones(HRZ)and 9.5%under critical risk zones(CRZ))followed by sub-zones IV(6.7%:HRZ;4.19%:CRZ)and VI(2.49%:HRZ;2.14%:CRZ).Future projection(2050)indicates a possible expansion of its distribution range across all agro-climatic sub-zones with dominance in sub-zones V and IV.Variable Bio_4(temperature seasonality)was observed as the most contributing factor for the distribution of L.camara for current and future scenarios across all RCPs.Suitable habitat for L.camara mostly occurred under natural vegetation(66.05%of CRZ and 60.71%of HRZ)and agriculture landscape(29.51%of CRZ and 34.48%of HRZ).Conclusions:The study provides an insight of invasion of L.camara in the plateau region of eastern India,and reveals wide distribution across all the agro-climatic sub-zones of Jharkhand,mostly in open and disturbed areas under natural vegetation and agriculture landscapes.Future projections for the year 2050 suggest a continuous increase in the expansion range of invasion across Jharkhand and call for urgent initiatives to combat its further invasion.
