BACKGROUND The standard treatment for advanced T2 gastric cancer(GC)is laparoscopic or surgical gastrectomy(either partial or total)and D2 lymphadenectomy.A novel combined endoscopic and laparoscopic surgery(NCELS)has...BACKGROUND The standard treatment for advanced T2 gastric cancer(GC)is laparoscopic or surgical gastrectomy(either partial or total)and D2 lymphadenectomy.A novel combined endoscopic and laparoscopic surgery(NCELS)has recently been proposed as a better option for T2 GC.Here we describe two case studies demonstrating the efficacy and safety of NCELS.CASE SUMMARY Two T2 GC cases were both resected by endoscopic submucosal dissection and full-thickness resection and laparoscopic lymph nodes dissection.This method has the advantage of being more precise and minimally invasive compared to current methods.The treatment of these 2 patients was safe and effective with no complications.These cases were followed up for nearly 4 years without recurrence or metastasis.CONCLUSION This novel method provides a minimally invasive treatment option for T2 GC,and its potential indications,effectiveness and safety needs to be further evaluated in controlled studies.展开更多
AIM: To access the short-term outcomes of simultaneous laparoscopic surgery combined with resection for synchronous lesions in patients with colorectal cancer. METHODS: Between March 1996 and April 2010 prospectively ...AIM: To access the short-term outcomes of simultaneous laparoscopic surgery combined with resection for synchronous lesions in patients with colorectal cancer. METHODS: Between March 1996 and April 2010 prospectively collected data were reviewed from 93 consecutive patients who had colorectal cancer and underwent simultaneous multiple organ resection (combined group) and 1090 patients who underwent conventional laparoscopic right hemicolectomy or laparoscopic low/ anterior resection for colorectal cancer (non-combined group). In the combined group, there were nine gastric resections, three nephrectomies, nine adrenalectomies, 56 cholecystectomies, and 21 gynecologic resections. In addition, f ive patients underwent simultaneous laparoscopic resection for three organs. The patient demographics, intra-operative outcomes, surgical morbidity, and short-term outcomes were compared between thetwo groups (the combined and non-combined groups). RESULTS: There were no signifi cant differences in the clinicopathological variables between the two groups. The operating time was signifi cantly longer in the combined group than in the non-combined group, regardless of tumor location (laparoscopic right hemicolectomy and laparoscopic low/anterior resection groups; P = 0.048 and P < 0.001, respectively). The other intraoperative outcomes, such as the complications and open conversion rate, were similar in both groups. The rate of post-operative morbidity in the combined group was similar to the non-combined group (combined vs non-combined, 15.1% vs 13.5%, P = 0.667). Oncological safety for the colon and synchronous lesions were obtained in the combined group. CONCLUSION: Simultaneous laparoscopic multiple organ resection combined with colorectal cancer is a safe and feasible option in selected patients.展开更多
目的:分析腹腔镜与内镜联合治疗对胆囊结石伴胆管结石患者的影响。方法:选取2022年5月—2023年5月贵州医科大学附属白云医院收治的70例胆囊结石伴胆管结石患者作为研究对象。根据随机数表法将其分为对照组和观察组,各35例。对照组给予...目的:分析腹腔镜与内镜联合治疗对胆囊结石伴胆管结石患者的影响。方法:选取2022年5月—2023年5月贵州医科大学附属白云医院收治的70例胆囊结石伴胆管结石患者作为研究对象。根据随机数表法将其分为对照组和观察组,各35例。对照组给予传统手术治疗,观察组给予腹腔镜与内镜联合治疗。比较两组术前、术后3 d疼痛情况及生活质量,围手术期指标及术后并发症。结果:术后3 d,观察组视觉模拟评分法(visual analogue scale,VAS)评分低于对照组,简明生活质量量表(the MOS item short form 36 health survey,SF-36)评分高于对照组,差异有统计学意义(P<0.05)。观察组术中出血量少于对照组,术后首次排气时间、住院时间均短于对照组,差异有统计学意义(P<0.05)。两组术后并发症发生率比较,差异无统计学意义(P>0.05)。结论:腹腔镜与内镜联合治疗胆囊结石伴胆管结石的效果显著,具有疼痛轻、术中出血量少、术后恢复快等优点,从而能提升患者生活质量。展开更多
目的探讨腹腔镜、胆道镜与十二指肠镜联合手术在胆囊结石合并胆总管结石患者中的应用价值.方法选择2019年10月—2022年10月该院收治的100例胆囊结石合并胆总管结石患者为研究对象,按随机数字表法分为两组.对照组(n=50)采用腹腔镜胆总管...目的探讨腹腔镜、胆道镜与十二指肠镜联合手术在胆囊结石合并胆总管结石患者中的应用价值.方法选择2019年10月—2022年10月该院收治的100例胆囊结石合并胆总管结石患者为研究对象,按随机数字表法分为两组.对照组(n=50)采用腹腔镜胆总管手术,观察组(n=50)采用腹腔镜、胆道镜与十二指肠镜联合手术.对比分析两组围术期指标、术后恢复情况、术后疼痛程度、术后并发症.结果观察组术中出血量(50.03±5.48)mL少于对照组的(63.58±7.12)mL,术后首次肛门排气时间(30.46±3.72)h、首次排便时间(34.78±2.51)h、首次进食时间(2.81±0.46)h、首次下床活动时间(43.63±6.54)h及住院时间(6.23±0.41)d均短于对照组的(37.04±3.95)h、(37.09±2.59)h、(3.29±0.43)h、(56.91±7.02)h、(7.01±0.52)d,组间差异有统计学意义(P<0.05).两组手术时间比较,差异无统计学意义(P>0.05).观察组术后6hVAS评分(4.02±0.61)分、术后12 h VAS评分(2.96±0.45)分、术后24 h VAS评分(2.11±0.28)分、术后48h VAS评分(1.62±0.25)分、并发症发生率4.00%均低于对照组的(4.53±0.79)分、(3.48±0.57)分、(2.87±0.31)分、(2.13±0.29)分、18.00%,组间差异有统计学意义(P<0.05).结论腹腔镜、胆道镜与十二指肠镜联合手术应用于胆囊结石合并胆总管结石患者中,可减少术中出血量,减轻患者术后疼痛,加快术后恢复,且并发症较少,有利于患者术后尽早出院,临床应用价值较高.展开更多
文摘BACKGROUND The standard treatment for advanced T2 gastric cancer(GC)is laparoscopic or surgical gastrectomy(either partial or total)and D2 lymphadenectomy.A novel combined endoscopic and laparoscopic surgery(NCELS)has recently been proposed as a better option for T2 GC.Here we describe two case studies demonstrating the efficacy and safety of NCELS.CASE SUMMARY Two T2 GC cases were both resected by endoscopic submucosal dissection and full-thickness resection and laparoscopic lymph nodes dissection.This method has the advantage of being more precise and minimally invasive compared to current methods.The treatment of these 2 patients was safe and effective with no complications.These cases were followed up for nearly 4 years without recurrence or metastasis.CONCLUSION This novel method provides a minimally invasive treatment option for T2 GC,and its potential indications,effectiveness and safety needs to be further evaluated in controlled studies.
文摘AIM: To access the short-term outcomes of simultaneous laparoscopic surgery combined with resection for synchronous lesions in patients with colorectal cancer. METHODS: Between March 1996 and April 2010 prospectively collected data were reviewed from 93 consecutive patients who had colorectal cancer and underwent simultaneous multiple organ resection (combined group) and 1090 patients who underwent conventional laparoscopic right hemicolectomy or laparoscopic low/ anterior resection for colorectal cancer (non-combined group). In the combined group, there were nine gastric resections, three nephrectomies, nine adrenalectomies, 56 cholecystectomies, and 21 gynecologic resections. In addition, f ive patients underwent simultaneous laparoscopic resection for three organs. The patient demographics, intra-operative outcomes, surgical morbidity, and short-term outcomes were compared between thetwo groups (the combined and non-combined groups). RESULTS: There were no signifi cant differences in the clinicopathological variables between the two groups. The operating time was signifi cantly longer in the combined group than in the non-combined group, regardless of tumor location (laparoscopic right hemicolectomy and laparoscopic low/anterior resection groups; P = 0.048 and P < 0.001, respectively). The other intraoperative outcomes, such as the complications and open conversion rate, were similar in both groups. The rate of post-operative morbidity in the combined group was similar to the non-combined group (combined vs non-combined, 15.1% vs 13.5%, P = 0.667). Oncological safety for the colon and synchronous lesions were obtained in the combined group. CONCLUSION: Simultaneous laparoscopic multiple organ resection combined with colorectal cancer is a safe and feasible option in selected patients.
文摘目的:分析腹腔镜与内镜联合治疗对胆囊结石伴胆管结石患者的影响。方法:选取2022年5月—2023年5月贵州医科大学附属白云医院收治的70例胆囊结石伴胆管结石患者作为研究对象。根据随机数表法将其分为对照组和观察组,各35例。对照组给予传统手术治疗,观察组给予腹腔镜与内镜联合治疗。比较两组术前、术后3 d疼痛情况及生活质量,围手术期指标及术后并发症。结果:术后3 d,观察组视觉模拟评分法(visual analogue scale,VAS)评分低于对照组,简明生活质量量表(the MOS item short form 36 health survey,SF-36)评分高于对照组,差异有统计学意义(P<0.05)。观察组术中出血量少于对照组,术后首次排气时间、住院时间均短于对照组,差异有统计学意义(P<0.05)。两组术后并发症发生率比较,差异无统计学意义(P>0.05)。结论:腹腔镜与内镜联合治疗胆囊结石伴胆管结石的效果显著,具有疼痛轻、术中出血量少、术后恢复快等优点,从而能提升患者生活质量。
文摘目的探讨腹腔镜、胆道镜与十二指肠镜联合手术在胆囊结石合并胆总管结石患者中的应用价值.方法选择2019年10月—2022年10月该院收治的100例胆囊结石合并胆总管结石患者为研究对象,按随机数字表法分为两组.对照组(n=50)采用腹腔镜胆总管手术,观察组(n=50)采用腹腔镜、胆道镜与十二指肠镜联合手术.对比分析两组围术期指标、术后恢复情况、术后疼痛程度、术后并发症.结果观察组术中出血量(50.03±5.48)mL少于对照组的(63.58±7.12)mL,术后首次肛门排气时间(30.46±3.72)h、首次排便时间(34.78±2.51)h、首次进食时间(2.81±0.46)h、首次下床活动时间(43.63±6.54)h及住院时间(6.23±0.41)d均短于对照组的(37.04±3.95)h、(37.09±2.59)h、(3.29±0.43)h、(56.91±7.02)h、(7.01±0.52)d,组间差异有统计学意义(P<0.05).两组手术时间比较,差异无统计学意义(P>0.05).观察组术后6hVAS评分(4.02±0.61)分、术后12 h VAS评分(2.96±0.45)分、术后24 h VAS评分(2.11±0.28)分、术后48h VAS评分(1.62±0.25)分、并发症发生率4.00%均低于对照组的(4.53±0.79)分、(3.48±0.57)分、(2.87±0.31)分、(2.13±0.29)分、18.00%,组间差异有统计学意义(P<0.05).结论腹腔镜、胆道镜与十二指肠镜联合手术应用于胆囊结石合并胆总管结石患者中,可减少术中出血量,减轻患者术后疼痛,加快术后恢复,且并发症较少,有利于患者术后尽早出院,临床应用价值较高.
