目的:观察Q开关紫翠宝石激光治疗色素沉着-息肉综合征的唇部皮疹的疗效。方法:采用波长752nm的调Q Al exandr i t e激光Phot Geni ca HT10治疗色素沉着-肠息肉综合征面部皮疹患者40例,并观察疗效。结果:治疗总显效率达100%,治愈率达52....目的:观察Q开关紫翠宝石激光治疗色素沉着-息肉综合征的唇部皮疹的疗效。方法:采用波长752nm的调Q Al exandr i t e激光Phot Geni ca HT10治疗色素沉着-肠息肉综合征面部皮疹患者40例,并观察疗效。结果:治疗总显效率达100%,治愈率达52.5%,治疗3次后大部分病例能获得痊愈。本组病例无1例出现瘢痕、色素沉着或色素减退。结论:752nm紫翠宝石激光治疗色素沉着-肠息肉综合征面部皮疹有明显的效果,是目前行之有效的较好方法。展开更多
Objective:Q-switched lasers,including 1064-nm Nd:YAG nansecond laser (QSNYL),755-nm alexandrite nanosecond laser (QSAL),and 694-nm nanosecond ruby laser (QSRL),are clinically available for the treatment of acquired bi...Objective:Q-switched lasers,including 1064-nm Nd:YAG nansecond laser (QSNYL),755-nm alexandrite nanosecond laser (QSAL),and 694-nm nanosecond ruby laser (QSRL),are clinically available for the treatment of acquired bilateral nevus of Ota-like macules (ABNOM).However,no reliable evidence from large-scale comparative studies identifies which type of laser works best.This study aims to determine the differences in the effectiveness,complications,and risk factors of QSNYL,QSAL,and QSRL in the treatment of ABNOM,further to provide evidence for clinician to make optimal choice according to the condition of patients.Methods:We collected the data from 685 ABNOM patients,including clinical features,medical treatments,and follow-up,since 1999 to 2014.The Kruskal-Wallis test was used to compare therapeutic differences between the three groups.The risk factors were analyzed using univariate analysis (x2 test) and multivariate logistic regression analysis.Results:The overall treatment efficiency of the QSNYL group (52.5%) and QSAL group (51.9%) was higher than that of the QSRL group (39.5%) (x2 =17.468,P < 0.001).The onset time of the QSRL and QSAL groups was shorter than that of the QSNYL group.The factors influencing efficacy in the QSNYL group were age at first treatment,number of treatments,coexistence with melesma,and the presence of hyperpigmentation;in the QSAL group was the number of treatments;and in the QSRL group was the number of treatments and hyperpigmentation.The prevalence of hyperpigrnentation in the QSNYL group (30.5%) and the QSAL group (27.5%) was lower than that of the QSRL group (47.3%) (X2=6.576,P<0.001).Concluslon:The QSNYL,QSAL,and QSRL are all effective and safe treatments for ABNOM.Considering the overall efficacy,duration of treatment,side effects,and risk factors,the QSAL is an optimal choice for ABNOM treatment.展开更多
文摘目的:观察Q开关紫翠宝石激光治疗色素沉着-息肉综合征的唇部皮疹的疗效。方法:采用波长752nm的调Q Al exandr i t e激光Phot Geni ca HT10治疗色素沉着-肠息肉综合征面部皮疹患者40例,并观察疗效。结果:治疗总显效率达100%,治愈率达52.5%,治疗3次后大部分病例能获得痊愈。本组病例无1例出现瘢痕、色素沉着或色素减退。结论:752nm紫翠宝石激光治疗色素沉着-肠息肉综合征面部皮疹有明显的效果,是目前行之有效的较好方法。
基金supported by grants from National Nature Science Foundation of China(No.81502739)Jiang Su National Nature Science Foundation(No.BK20150068)Medical Science and Technology Innovation Project of Chinese Academy of Medical Sciences(No.CIFMS-2017-I2M-1-017)
文摘Objective:Q-switched lasers,including 1064-nm Nd:YAG nansecond laser (QSNYL),755-nm alexandrite nanosecond laser (QSAL),and 694-nm nanosecond ruby laser (QSRL),are clinically available for the treatment of acquired bilateral nevus of Ota-like macules (ABNOM).However,no reliable evidence from large-scale comparative studies identifies which type of laser works best.This study aims to determine the differences in the effectiveness,complications,and risk factors of QSNYL,QSAL,and QSRL in the treatment of ABNOM,further to provide evidence for clinician to make optimal choice according to the condition of patients.Methods:We collected the data from 685 ABNOM patients,including clinical features,medical treatments,and follow-up,since 1999 to 2014.The Kruskal-Wallis test was used to compare therapeutic differences between the three groups.The risk factors were analyzed using univariate analysis (x2 test) and multivariate logistic regression analysis.Results:The overall treatment efficiency of the QSNYL group (52.5%) and QSAL group (51.9%) was higher than that of the QSRL group (39.5%) (x2 =17.468,P < 0.001).The onset time of the QSRL and QSAL groups was shorter than that of the QSNYL group.The factors influencing efficacy in the QSNYL group were age at first treatment,number of treatments,coexistence with melesma,and the presence of hyperpigmentation;in the QSAL group was the number of treatments;and in the QSRL group was the number of treatments and hyperpigmentation.The prevalence of hyperpigrnentation in the QSNYL group (30.5%) and the QSAL group (27.5%) was lower than that of the QSRL group (47.3%) (X2=6.576,P<0.001).Concluslon:The QSNYL,QSAL,and QSRL are all effective and safe treatments for ABNOM.Considering the overall efficacy,duration of treatment,side effects,and risk factors,the QSAL is an optimal choice for ABNOM treatment.
