Real time detection of antibody-antigen interaction using a laser scanning confocal imaging-surface plasmon resonance system

A laser scanning confocal imaging-surface plasmon resonance （LSCI-SPR） instrument integrated with a wavelength-dependent surface plasmon resonance （SPR） sensor and a laser scanning confocal microscopy （LSCM） is built to detect the bonding process of human IgG and fluorescent-labeled affinity purified antibodies in real time. The shifts of resonant wavelength at different reaction time stages are obtained by SPR, corresponding well with the changes of the fluorescence intensity collected by using LSCM. The instrument shows the merits of the combination and complementation of the SPR and LSCM, with such advantages as quantificational analysis, high spatial resolution and real time monitor, which are of great importance for practical applications in biosensor and life science.

Noise suppression for the detection laser of a nuclear magnetic resonance gyroscope based on a liquid crystal variable retarder

Nuclear magnetic resonance gyroscopes （NMRGs） are a kind of rotation-speed sensor that senses the angular velocity by measuring a frequency shift in the Larmor pre- cession of the nuclear spin in a constant magnetic field.

The phenomenon of stochastic resonance in a single-mode laser system with an input periodical signal

Using the linear approximation method, we study a single-mode laser system driven by colored pump noise and quantum noise with coupling between the real and imaginary parts when the laser is operated well above threshold. The steady state mean intensity fluctuation C(0) and signal-to-noise ratio (SNR) are calculated. It is found that there is a maximum in SNR when there is a minimum in the fluctuation of laser system if the coupling coefficient between real and imaginary parts of the quantum noise equals zero.

Harmonic dissipative soliton resonance pulses in a fiber ring laser at different values of anomalous dispersion

The pulse dynamics of harmonic mode-locking in a dissipative soliton resonance(DSR) region in an erbiumdoped fiber ring laser is investigated at different values of anomalous dispersion. The fiber laser is mode-locked by a nonlinear polarization rotation technique. By inserting 0–200 m anomalous dispersion single-mode fiber in the laser cavity, the cavity length is changed from 17.3 to 217.3 m, and the corresponding dispersion of the cavity ranges from -0.27 to-4.67 ps^2. The observed results show that the tuning range of repetition rate under a harmonic DSR condition is highly influenced by the cavity dispersion. Furthermore, it is found that, by automatically adjusting their harmonic orders, the lasers can work at certain values of repetition rate, which are independent of the cavity length and dispersion. The pulses at the same repetition rate in different laser configurations have similar properties, demonstrating that each achievable repetition rate represents an operation regime of harmonic DSR lasers.

Widely tunable laser frequency offset locking to the atomic resonance line with frequency modulation spectroscopy

A simple and robust technique is reported to offset lock a single semiconductor laser to the atom resonance line with a frequency difference easily adjustable from a few tens of megahertz up to tens of gigahertz. The proposed scheme makes use of the frequency modulation spectroscopy by modulating sidebands of a fiber electro-optic modulator output. The short-term performances of a frequency offset locked semiconductor laser are experimentally demonstrated with the Allan variance of around 3.9 × 10-11 at a 2 s integration time. This method may have many applications, such as in Raman optics for an atom interferometer.

Modulation-free laser frequency ofset locking using bufer gas-induced resonance

We experimentally demonstrate a simple modulation-free scheme for ofset locking the frequency of a laser using bufer gas-induced resonance. Our scheme excludes the limitation of low difraction efciency and laser input intensity when an acousto-optic modulator is applied to shift the laser frequency from the resonance. We show the stabilization of a strong 795- nm laser detuned up to 550 MHz from the 87Rb 5S1/2 F=2→5P1/2F'=2 transition. The locking range can be modifed by controlling the bufer gas pressure. A laser line width of 2 MHz is achieved over 10 min.

VIBRATION MEASUREMENT OF DOUBLE-ENDED TUNING FORKS RESONATOR

To enhance the coherence and reliability of the double-ended tuning fork （DETF） resonator, a measurement system of resonator vibration is presented to check its dynamic characteristics. Laser Doppler techniques are utilized and the relation between DETF vibration velocity and output current of photodetector is obtained. Resonator vibration equation is also analyzed and its driving power only depends on the direct current bias voltage and the amplitude of alternative voltage. Furthermore, a special resonator driving control circuit based on measurement is designed. The amplitude and frequency of circuit is controlled by a computer so that highly stable and strong driving signal can be output. Experiments on driving and measuring double-ended tuning fork have been done, The frequency of driving signal is 8 kHz and the peak-to-peak value of driving voltage is 140 V. Experimental results indicate resonator can be drived stably by driving control circuit and dynamic characteristics of DETF may be measured in real time.

Experimental study on resonance frequency enhancement of strong optical injection-locked semiconductor lasers

Enhancing resonance frequency of strong optical studied. Resonance frequency is increased from technique. We experimentally demonstrate that injection-locked semiconductor lasers is experimentally 4.1 to 53.9 GHz by the optical injection locking （OIL） resonance frequency is strictly equal to the frequency spacing between the cavity modes of the master and slave lasers under strong OIL condition. This result provides valuable information to improve OIL theory.

Diode-pumped 1123-nm Nd:YAG laser

We demonstrated a diode-pumped Nd:YAG laser with a plano-concave resonator. When the pump power is 1.57 W, the output power of 1123-nm laser is 132 mW at the temperature of 20 ℃, and the power change is less than 2% in an hour. A periodically poled LiNbO3 (PPLN) was used as outer cavity frequency-doubling crystal and 561-nm laser was observed.

External cavity diode laser as a stable-frequency light source for application in laser cooling of molecules

We demonstrate a scheme to use a Littman configuration external cavity diode laser （ECDL） as a stablefrequency light source to stabilize two cw single-mode Ti：sapphire lasers for laser cooling of magnesium fluoride molecules. An ECDL based on the Littman configuration is constructed and stabilized by a digital signal processor system. We stabilize the frequency of our ECDL to 4-0.77 MHz precision over 10 h and the Allan standard deviation reaches 2.6 × 10-11 at an integration time of 10 s. We lock two Ti：sapphire lasers through a transfer cavity, and either laser has a long-term frequency stability of 4-2.5 MHz.

Compact phase-lock loop for external cavity diode lasers

We present a compact, low-noise, and inexpensive optical phase-lock loop （OPLL） system to synchronize the frequency and the phase between two external cavity diode lasers. Based on a direct digital synthesizer tech- nique, a programmable radio-frequency generator is implemented as the reference signal source. The OPLL has a narrow beat note linewidth below 1 Hz and a residual mean-square phase error of 0.06 rad2 in a 10 MHz integration bandwidth. The experimental test results prove the competent performance of the system, which is promising as a low-budget choice in atomic physics applications.

Parameter study of RF excited diffusively cooled all-metal slab waveguide CO_2 laser

In this paper, we have investigated some parameters of a radio frequency (RF) excited diffusively cooled all-metal slab waveguide CO2 laser based on the modified Rigrod theory by introducing a waveguide coupling efficiency which designates the coupling between the waveguide and the resonator mirrors. The parameters of the laser small signal gain go, saturation intensity Is, and waveguide coupling efficiency ηare studied theoretically and experimentally. In the experiments, three sets of output coupling flat mirrors with the different transitivities were used, and a maximum laser power output of 150 W was obtained from a gas discharge region of 2-mm height, 20-mm width, and 386-mm length coupled with a CASE-I optical waveguide resonator.

Laser beam characteristic for laser resonators with diffraction optical elements

The matrix eigenvalue method is used to analyze a laser resonator composed of diffraction optical elements. The results show that this type of resonator can separate fundamental mode and high order modes effectively. The output beams can be designed for different requests.

Investigation on characteristics of self-organization Mach-Zehnder erbium-doped fiber laser cavity

The characteristics of coherent coupling in Mach-Zehnder erbium-doped fiber laser cavity are experimentally studied. By virtue of a seemly controlling of length difference between two interferometric arms, the obtained comb-like spectrum of interferometer resonator with a period of 0.06 nm commendably agrees with the theory of self-organization coherence. The coherent output exits from the output mirror of a fiber Bragg grating with 4.5% reflectivity. A high coherent combining efficiency of 94% is obtained. Investigation on characteristics of the leak power opens out self-organization mechanism in Mach-Zehnder composite cavity.

Coherent combining of tunable erbium-doped fiber lasers by a single-mode fiber feedback loop

We experimentally demonstrate the coherent combining of two tunable erbium-doped fiber lasers by using a single-mode fiber feedback loop configuration. A single-mode fiber is arranged in the feedback loop to filter the far-field pattern, and the energy of desired in-phase mode is collected and injected into the resonators of two component fiber lasers. The coherently combined laser is tunable over a wide spectrum ranging from 1536 to 1569 nm, which means that the combining scheme is compatible with wavelength tuning. The effects and necessity of whether adopting polarization controlling measures or not in component lasers are investigated in detail. The results indicate that adding polarization controlling can improve the array＇s coherence, whereas it will decrease the output power and efficiency simultaneously.

All-solid-state doubly resonant sum-frequency continuous-wave laser at 555 nm

A new kind of resonator for doubly resonant continuous-wave （CW） intracavity sum-frequency mixing （SFM） is presented. A coherent radiation of 327 mW at 555 nm is generated by mixing 1342-nm Nd：YVO4 laser and 946-nm Nd：YAG laser. The M^2 beam quality factor of the sum-frequency mixed yellow-green laser is less than 1.7. The low-noise characteristic of the yellow laser is demonitrated.

Diode-pumped vertical external cavity surface emitting laser at 1 μm

We demonstrated a diode-pumped vertical external cavity surface emitting laser with simple plane-concave cavity. When the pump power at a wavelength of 811.6 nm is 1.5 W, the maximum output power is 40.4 mW at the wavelength of 1005.8 nm. The optical-optical conversion efficiency is 2.7%. .

Quantum wells micro-ring resonator laser emitting at 1746 nm for gas sensing

Gas sensing for measurement of gas components, concentrations, and other parameters plays an important role in many fields. In this Letter, a micro-ring resonator laser used for gas sensing is experimentally demonstrated. The multi-quantumwells micro-ring laser based on whispering-gallery modes with an annular resonator and an output waveguide was fabricated. A single-mode laser with a wavelength of 1746.4 nm was fabricated for the first time, to the best of our knowledge,experimentally. The output power of 1.65 m W under 40 m A injection current was obtained with a side-mode suppression ratio over 33 d B.

Demonstration of an ultra-low-threshold phonon laser with coupled microtoroid resonators in vacuum

We demonstrate an ultra-low-threshold phonon laser using a coupled-microtoroid-cavity system by introducing a novel coupling approach.The scheme exhibits both high optical quality factors and high mechanical quality factors.We have experimentally obtained the mechanical quality factor up to 18,000 in vacuum for a radialbreathing mode of 59.2 MHz.The measured phonon lasing threshold is as low as 1.2μW,which is～5 times lower than the previous result.

Resonator integrated optic gyro based on multilevel laser frequency lock-in technique

The resonator integrated optic gyros（RIOGs） based on the Sagnac effect have gained extensive attention in navigation and guidance systems due to their predominant advantages： high theoretical accuracy and simple integration. However, the problems of losing lock and low lock-in accuracy are the bottlenecks, which restrict the development of digital RIOGs. Therefore, a multilevel laser frequency lock-in technique has been proposed in this Letter to address these problems. The experimental results show that lock-in accuracy can be improved one order higher and without losing lock in a variable temperature environment. Then, a digital miniaturized RIOG prototype（18 cm × 18 cm × 20 cm） has been produced, and long-term（1 h） bias stability of 26.6 deg/h is successfully demonstrated.