The left atrium (LA) has been recognized as a morphophysiological barometer of left ventricular (LV) diastolic dysfunction. Because in the myocardial ischemia cascade where LV diastolic dysfunction often precedes LV s...The left atrium (LA) has been recognized as a morphophysiological barometer of left ventricular (LV) diastolic dysfunction. Because in the myocardial ischemia cascade where LV diastolic dysfunction often precedes LV systolic dysfunction, the LA which fashions as an early marker of diastolic anomaly, could equally reflect a declining LV function and/or be a good predictor of potential sequelae. We assessed this association of LA function with reduced LV systolic function among hospitalized patients. Among patients with reduced LV ejection fraction, LA passive ejection fraction was lower (0.172 ± 0.12 vs. 0.232 ± 0.14, p = 0.013) whereas LA kinetic energy was higher (6.48 ± 6.3 vs. 4.57 ± 3.5, p = 0.005). Echocardiographic assessment of LA function, therefore, appears correlated with LVEF and could be important when risk stratifying hospitalized patients.展开更多
Some studies have shown that left ventricular structure and function play an important role in the risk stratifi cation and prognosis of cardiovascular disease.The clinical application of left atrial function in cardi...Some studies have shown that left ventricular structure and function play an important role in the risk stratifi cation and prognosis of cardiovascular disease.The clinical application of left atrial function in cardiovascular disease has gradually attracted attention in the cardiovascular fi eld.There are many traditional methods to evaluate left atrial function.Left atrial function related indexes measured by echocardiography has been identifi ed as a powerful predictor of cardiovascular disease in recent years,but they have some limitations.The left atrial function index has been found to evaluate left atrial function more effectively than traditional parameters.Furthermore,it is a valuable predictor of the risk stratifi cation and prognosis in patients with clinical cardiovascular disease such as heart failure,atrial fi brillation,hypertension,and coronary heart disease.展开更多
Objective To evaluate left atrial function in essential hypertension patients with different patterns of left ventricular geometric models by real-time three-dimensional echocardiography （RT-3DE） and left atrial tra...Objective To evaluate left atrial function in essential hypertension patients with different patterns of left ventricular geometric models by real-time three-dimensional echocardiography （RT-3DE） and left atrial tracking （EAT）.展开更多
Background: The aim of this study was to determine the relation of left atrial (LA) volume and LA volume index with left ventricular function and to determine the association of duration of symptoms and left atrial vo...Background: The aim of this study was to determine the relation of left atrial (LA) volume and LA volume index with left ventricular function and to determine the association of duration of symptoms and left atrial volume index in patients with dilated cardiomyopathy. Materials and Methods: This was an observational, single centre study conducted in India. A total of 50 patients who were admitted to department of cardiology from July, 2008 to February, 2009 with diagnosis of dilated cardiomyopathy and an ejection fraction of <40% were included. Results: Of the 50 patients, 34 (68%) were males. 27 (54%) patients were in NYHA class II and 23 (46%) patients were in NYHA class III. LA volume was found to be ≥40 ml in all patients. LV function and LA volume were found to be correlated (r = -0.789, p < 0.01). Similarly, there was a correlation between LV function and LA volume index (r = -0.826, p < 0.01). There was no correlation between LA volume index and duration of symptoms (r = 0.04). Conclusion: It can be concluded that there is a strong inverse correlation between LA volume and left ventricular function and also between LA volume index and left ventricular function. The patients with NYHA class III were having larger left atrial volume than those with NYHA class II. Moreover, the duration of symptoms has no correlation with left atrial volume index.展开更多
目的应用四维自动左房定量技术(4D Auto LAQ)评价不同透析方式对尿毒症患者左房结构和功能的影响。方法选取于我院肾内科就诊的尿毒症患者80例,根据透析方式分为血液透析组39例和腹膜透析组41例,另选同期健康体检者35例作为正常对照组...目的应用四维自动左房定量技术(4D Auto LAQ)评价不同透析方式对尿毒症患者左房结构和功能的影响。方法选取于我院肾内科就诊的尿毒症患者80例,根据透析方式分为血液透析组39例和腹膜透析组41例,另选同期健康体检者35例作为正常对照组。应用常规超声心动图获取左室射血分数(LVEF)、左房内径(LAD)、左室舒张末期内径(LVEDD)、室间隔厚度(IVS)、左室后壁厚度(LVPW);4D Auto LAQ获取左房应变参数,包括左房储备期纵向应变(LASr)、左房管道期纵向应变(LAScd)、左房收缩期纵向应变(LASct)、左房储备期环形应变(LASr-c)、左房管道期环形应变(LAScd-c)、左房收缩期环形应变(LASct-c),以及左房容积参数,包括左房最大容积(LAVmax)、左房最小容积(LAVmin)、左房收缩前容积(LAVpreA)、左房射血分数(LAEF),比较各组上述参数的差异;分析LAEF与左房应变参数的相关性。结果①各组常规超声心动图参数比较:腹膜透析组和血液透析组LAD、LVEDD、IVS、LVPW均较正常对照组增大,差异均有统计学意义(均P<0.05);各组LVEF比较差异无统计学意义。②各组4D Auto LAQ左房应变参数比较:与正常对照组比较,腹膜透析组LASr、LAScd、LASr-c、LAScd-c均减小,LASct、LASct-c均增大,血液透析组LASr、LAScd、LASct、LASr-c、LAScd-c、LASct-c均减小,差异均有统计学意义(均P<0.05);除LAScd外,血液透析组LASr、LAScd、LASct、LASr-c、LAScd-c、LASct-c均较腹膜透析组减小,差异均有统计学意义(均P<0.05)。③各组4D Auto LAQ左房容积参数比较:与正常对照组比较,腹膜透析组LAVmax、LAVmin、LAVpreA均增大,LAEF减小,血液透析组LAVmax、LAVmin、LAVpreA均增大,LAEF减小,差异均有统计学意义(均P<0.05);与腹膜透析组比较,血液透析组LAVmax、LAmin、LAVpreA均增大,LAEF减小,差异均有统计学意义(均P<0.05)。④相关性分析显示,LAEF与LASr、LAScd、LASr-c、LAScd-c、LASct、LASct-c均呈正相关(r=0.531、0.522、0.705、0.686、0.306、0.376,均P<0.001)。结论4D Auto LAQ可用于评价不同透析方式对尿毒症患者左房结构和功能的影响,其中血液透析较腹膜透析对左房结构和功能影响更大。展开更多
文摘The left atrium (LA) has been recognized as a morphophysiological barometer of left ventricular (LV) diastolic dysfunction. Because in the myocardial ischemia cascade where LV diastolic dysfunction often precedes LV systolic dysfunction, the LA which fashions as an early marker of diastolic anomaly, could equally reflect a declining LV function and/or be a good predictor of potential sequelae. We assessed this association of LA function with reduced LV systolic function among hospitalized patients. Among patients with reduced LV ejection fraction, LA passive ejection fraction was lower (0.172 ± 0.12 vs. 0.232 ± 0.14, p = 0.013) whereas LA kinetic energy was higher (6.48 ± 6.3 vs. 4.57 ± 3.5, p = 0.005). Echocardiographic assessment of LA function, therefore, appears correlated with LVEF and could be important when risk stratifying hospitalized patients.
基金This work was supported by grants from the National Natural Science Foundation of China(81800056),the Science&Technology Development Fund of Tianjin Education Commission for Higher Education(2017KJ137),and the Key Research and Development Program of Hunan Province(2019SK2021).Scientifi c research project approved by Hunan Provincial Health Commission(202103012117).
文摘Some studies have shown that left ventricular structure and function play an important role in the risk stratifi cation and prognosis of cardiovascular disease.The clinical application of left atrial function in cardiovascular disease has gradually attracted attention in the cardiovascular fi eld.There are many traditional methods to evaluate left atrial function.Left atrial function related indexes measured by echocardiography has been identifi ed as a powerful predictor of cardiovascular disease in recent years,but they have some limitations.The left atrial function index has been found to evaluate left atrial function more effectively than traditional parameters.Furthermore,it is a valuable predictor of the risk stratifi cation and prognosis in patients with clinical cardiovascular disease such as heart failure,atrial fi brillation,hypertension,and coronary heart disease.
基金Supported by the Natural Science Foundation of Liaoning ProvinceChina(2013023010)
文摘Objective To evaluate left atrial function in essential hypertension patients with different patterns of left ventricular geometric models by real-time three-dimensional echocardiography （RT-3DE） and left atrial tracking （EAT）.
文摘Background: The aim of this study was to determine the relation of left atrial (LA) volume and LA volume index with left ventricular function and to determine the association of duration of symptoms and left atrial volume index in patients with dilated cardiomyopathy. Materials and Methods: This was an observational, single centre study conducted in India. A total of 50 patients who were admitted to department of cardiology from July, 2008 to February, 2009 with diagnosis of dilated cardiomyopathy and an ejection fraction of <40% were included. Results: Of the 50 patients, 34 (68%) were males. 27 (54%) patients were in NYHA class II and 23 (46%) patients were in NYHA class III. LA volume was found to be ≥40 ml in all patients. LV function and LA volume were found to be correlated (r = -0.789, p < 0.01). Similarly, there was a correlation between LV function and LA volume index (r = -0.826, p < 0.01). There was no correlation between LA volume index and duration of symptoms (r = 0.04). Conclusion: It can be concluded that there is a strong inverse correlation between LA volume and left ventricular function and also between LA volume index and left ventricular function. The patients with NYHA class III were having larger left atrial volume than those with NYHA class II. Moreover, the duration of symptoms has no correlation with left atrial volume index.
文摘目的应用四维自动左房定量技术(4D Auto LAQ)评价不同透析方式对尿毒症患者左房结构和功能的影响。方法选取于我院肾内科就诊的尿毒症患者80例,根据透析方式分为血液透析组39例和腹膜透析组41例,另选同期健康体检者35例作为正常对照组。应用常规超声心动图获取左室射血分数(LVEF)、左房内径(LAD)、左室舒张末期内径(LVEDD)、室间隔厚度(IVS)、左室后壁厚度(LVPW);4D Auto LAQ获取左房应变参数,包括左房储备期纵向应变(LASr)、左房管道期纵向应变(LAScd)、左房收缩期纵向应变(LASct)、左房储备期环形应变(LASr-c)、左房管道期环形应变(LAScd-c)、左房收缩期环形应变(LASct-c),以及左房容积参数,包括左房最大容积(LAVmax)、左房最小容积(LAVmin)、左房收缩前容积(LAVpreA)、左房射血分数(LAEF),比较各组上述参数的差异;分析LAEF与左房应变参数的相关性。结果①各组常规超声心动图参数比较:腹膜透析组和血液透析组LAD、LVEDD、IVS、LVPW均较正常对照组增大,差异均有统计学意义(均P<0.05);各组LVEF比较差异无统计学意义。②各组4D Auto LAQ左房应变参数比较:与正常对照组比较,腹膜透析组LASr、LAScd、LASr-c、LAScd-c均减小,LASct、LASct-c均增大,血液透析组LASr、LAScd、LASct、LASr-c、LAScd-c、LASct-c均减小,差异均有统计学意义(均P<0.05);除LAScd外,血液透析组LASr、LAScd、LASct、LASr-c、LAScd-c、LASct-c均较腹膜透析组减小,差异均有统计学意义(均P<0.05)。③各组4D Auto LAQ左房容积参数比较:与正常对照组比较,腹膜透析组LAVmax、LAVmin、LAVpreA均增大,LAEF减小,血液透析组LAVmax、LAVmin、LAVpreA均增大,LAEF减小,差异均有统计学意义(均P<0.05);与腹膜透析组比较,血液透析组LAVmax、LAmin、LAVpreA均增大,LAEF减小,差异均有统计学意义(均P<0.05)。④相关性分析显示,LAEF与LASr、LAScd、LASr-c、LAScd-c、LASct、LASct-c均呈正相关(r=0.531、0.522、0.705、0.686、0.306、0.376,均P<0.001)。结论4D Auto LAQ可用于评价不同透析方式对尿毒症患者左房结构和功能的影响,其中血液透析较腹膜透析对左房结构和功能影响更大。
