Objective: To observe the effect of acupuncture therapy on the function of myocardial contraction in symptomless cardiac failure patients.Methods: A total of 60 cases of symptomless cardiac insufficiency inpatients we...Objective: To observe the effect of acupuncture therapy on the function of myocardial contraction in symptomless cardiac failure patients.Methods: A total of 60 cases of symptomless cardiac insufficiency inpatients were randomly divided into medication and acupuncture groups, with 30 cases in each group. For patients of acupuncture group, Neiguan (PC 6), Ximen (PC 4), Tanzhong (CV 17), Xinshu (BL 15), Jueyinshu (BL 14) and Geshu (BL 17) were punctured, twice daily, with 30 days being a therapeutic course. In medication group, patients were asked to take Capoten 25 mg (t.i.d.). The left ventricular ejection fraction (LVEF) and its fractional shortening (FS) of the minor axis were used as the indexes for assessing the therapeutic effect and detected by using a color ultrasonic Doppler apparatus. Results: After one course of treatment, of the each 30 cases of acupuncture and medication groups, 13 (43.3%) and 16 (53.3%) had marked improvement, 16 (53.3%) and 14 (46.7%) had improvement, and 1 (3.3%) and 0 had no any effect respectively. No significant difference was found between two groups in the therapeutic effect. It shows acupuncture therapy can improve myocardial contraction function. Conclusion: Acupuncture has a similar effect in enhancing the systolic function of the myocardium.展开更多
Background:Postural tachycardia syndrome(POTS)is a common childhood disease that seriously affects the patient’s physical and mental health.This study aimed to investigate whether pre-treatment baseline left ventricu...Background:Postural tachycardia syndrome(POTS)is a common childhood disease that seriously affects the patient’s physical and mental health.This study aimed to investigate whether pre-treatment baseline left ventricular ejection fraction(LVEF)and left ventricular fractional shortening(LVFS)values were associated with symptom improvement after metoprolol therapy for children and adolescents with POTS.Methods:This retrospective study evaluated 51 children and adolescents with POTS who received metoprolol therapy at the Peking University First Hospital between November 2010 and July 2019.All patients had completed a standing test or basic head-up tilt test and cardiac echocardiography before treatment.Treatment response was evaluated 3 months after starting metoprolol therapy.The pre-treatment baseline LVEF and LVFS values were evaluated for correlations with decreases in the symptom score after treatment(DSS).Multivariable analysis was performed using factors with a P value of<0.100 in the univariate analyses and the demographic characteristics.Results:A comparison of responders and non-responders revealed no significant differences in demographic,hemodynamic characteristics,and urine specific gravity(all P>0.050).However,responders had significantly higher baseline LVEF(71.09%±4.44%vs.67.17%±4.88%,t=2.789,P=0.008)and LVFS values(40.00[38.00,42.00]%vs.36.79%±4.11%,Z=2.542,P=0.010)than the non-responders.The baseline LVEF and LVFS were positively correlated with DSS(r=0.378,P=0.006;r=0.363,P=0.009),respectively.Logistic regression analysis revealed that LVEF was independently associated with the response to metoprolol therapy in children and adolescents with POTS(odds ratio:1.201,95%confidence interval:1.039–1.387,P=0.013).Conclusions:Pre-treatment baseline LVEF was associated with symptom improvement after metoprolol treatment for children and adolescents with POTS.展开更多
目的与超声心动图对比,探讨冠状动脉C T血管造影(C o m p u t e d To m o g r a p h i c Angiography,CTA)测量左心室功能的应用价值。方法搜集我院43例行冠状动脉CTA及超声心动图(Echocardiography,EC)患者资料,其中男16例,女27例,年龄...目的与超声心动图对比,探讨冠状动脉C T血管造影(C o m p u t e d To m o g r a p h i c Angiography,CTA)测量左心室功能的应用价值。方法搜集我院43例行冠状动脉CTA及超声心动图(Echocardiography,EC)患者资料,其中男16例,女27例,年龄44~87岁,平均(62.2±8.7)岁,EC在CTA检查后48 h内进行。应用心血管后处理软件测算射血分数(Ejection Fraction,EF)、左心室收缩率(Fractional Shortening,FS)等参数,比较冠状动脉CTA与EC所得EF、FS有无差异,计算CTA与EC结果的相关性及一致性。结果冠状动脉CTA与EC所得EF、FS结果分别为(64.05±5.74)%,(60.81±4.6)%;(26.42±3.68)%,(31.16±3.66)%;两者比较均有统计学差异(t=6.94,P=0.000;t=-16.5,P=0.000)。两种方法测量所得EF、ES均有较好的相关性及一致性(r=0.85,P=0.000,偏倚3.05%;r=0.87,P=0.000,偏倚1.89%)。结论应用冠状动脉CTA可以方便快捷地测量左心室功能,且与EC测量结果具有较好的相关性及一致性。展开更多
文摘Objective: To observe the effect of acupuncture therapy on the function of myocardial contraction in symptomless cardiac failure patients.Methods: A total of 60 cases of symptomless cardiac insufficiency inpatients were randomly divided into medication and acupuncture groups, with 30 cases in each group. For patients of acupuncture group, Neiguan (PC 6), Ximen (PC 4), Tanzhong (CV 17), Xinshu (BL 15), Jueyinshu (BL 14) and Geshu (BL 17) were punctured, twice daily, with 30 days being a therapeutic course. In medication group, patients were asked to take Capoten 25 mg (t.i.d.). The left ventricular ejection fraction (LVEF) and its fractional shortening (FS) of the minor axis were used as the indexes for assessing the therapeutic effect and detected by using a color ultrasonic Doppler apparatus. Results: After one course of treatment, of the each 30 cases of acupuncture and medication groups, 13 (43.3%) and 16 (53.3%) had marked improvement, 16 (53.3%) and 14 (46.7%) had improvement, and 1 (3.3%) and 0 had no any effect respectively. No significant difference was found between two groups in the therapeutic effect. It shows acupuncture therapy can improve myocardial contraction function. Conclusion: Acupuncture has a similar effect in enhancing the systolic function of the myocardium.
基金the Science and Technology Program of Beijing(Z171100001017253)Beijing Natural Science Foundation(7182168)+1 种基金Peking University Clinical Scientist Program(BMU2019LCKXJ001,Beijing,China)the Fundamental Research Funds for the Central Universities.
文摘Background:Postural tachycardia syndrome(POTS)is a common childhood disease that seriously affects the patient’s physical and mental health.This study aimed to investigate whether pre-treatment baseline left ventricular ejection fraction(LVEF)and left ventricular fractional shortening(LVFS)values were associated with symptom improvement after metoprolol therapy for children and adolescents with POTS.Methods:This retrospective study evaluated 51 children and adolescents with POTS who received metoprolol therapy at the Peking University First Hospital between November 2010 and July 2019.All patients had completed a standing test or basic head-up tilt test and cardiac echocardiography before treatment.Treatment response was evaluated 3 months after starting metoprolol therapy.The pre-treatment baseline LVEF and LVFS values were evaluated for correlations with decreases in the symptom score after treatment(DSS).Multivariable analysis was performed using factors with a P value of<0.100 in the univariate analyses and the demographic characteristics.Results:A comparison of responders and non-responders revealed no significant differences in demographic,hemodynamic characteristics,and urine specific gravity(all P>0.050).However,responders had significantly higher baseline LVEF(71.09%±4.44%vs.67.17%±4.88%,t=2.789,P=0.008)and LVFS values(40.00[38.00,42.00]%vs.36.79%±4.11%,Z=2.542,P=0.010)than the non-responders.The baseline LVEF and LVFS were positively correlated with DSS(r=0.378,P=0.006;r=0.363,P=0.009),respectively.Logistic regression analysis revealed that LVEF was independently associated with the response to metoprolol therapy in children and adolescents with POTS(odds ratio:1.201,95%confidence interval:1.039–1.387,P=0.013).Conclusions:Pre-treatment baseline LVEF was associated with symptom improvement after metoprolol treatment for children and adolescents with POTS.
文摘目的与超声心动图对比,探讨冠状动脉C T血管造影(C o m p u t e d To m o g r a p h i c Angiography,CTA)测量左心室功能的应用价值。方法搜集我院43例行冠状动脉CTA及超声心动图(Echocardiography,EC)患者资料,其中男16例,女27例,年龄44~87岁,平均(62.2±8.7)岁,EC在CTA检查后48 h内进行。应用心血管后处理软件测算射血分数(Ejection Fraction,EF)、左心室收缩率(Fractional Shortening,FS)等参数,比较冠状动脉CTA与EC所得EF、FS有无差异,计算CTA与EC结果的相关性及一致性。结果冠状动脉CTA与EC所得EF、FS结果分别为(64.05±5.74)%,(60.81±4.6)%;(26.42±3.68)%,(31.16±3.66)%;两者比较均有统计学差异(t=6.94,P=0.000;t=-16.5,P=0.000)。两种方法测量所得EF、ES均有较好的相关性及一致性(r=0.85,P=0.000,偏倚3.05%;r=0.87,P=0.000,偏倚1.89%)。结论应用冠状动脉CTA可以方便快捷地测量左心室功能,且与EC测量结果具有较好的相关性及一致性。