Since the efficiency of treatment of thyroid disorder depends on the risk of malignancy, indeterminate follicular neoplasm (FN) images should be classified. The diagnosis process has been done by visual interpretation...Since the efficiency of treatment of thyroid disorder depends on the risk of malignancy, indeterminate follicular neoplasm (FN) images should be classified. The diagnosis process has been done by visual interpretation of experienced pathologists. However, it is difficult to separate the favor benign from borderline types. Thus, this paper presents a classification approach based on 3D nuclei model to classify favor benign and borderline types of follicular thyroid adenoma (FTA) in cytological specimens. The proposed method utilized 3D gray level co-occurrence matrix (GLCM) and random forest classifier. It was applied to 22 data sets of FN images. Furthermore, the use of 3D GLCM was compared with 2D GLCM to evaluate the classification results. From experimental results, the proposed system achieved 95.45% of the classification. The use of 3D GLCM was better than 2D GLCM according to the accuracy of classification. Consequently, the proposed method probably helps a pathologist as a prescreening tool.展开更多
AIM: To develop an automatic tool on screening diabetic retinopathy(DR) from diabetic patients.METHODS: We extracted textures from eye fundus images of each diabetes subject using grey level co-occurrence matrix metho...AIM: To develop an automatic tool on screening diabetic retinopathy(DR) from diabetic patients.METHODS: We extracted textures from eye fundus images of each diabetes subject using grey level co-occurrence matrix method and trained a Bayesian model based on these textures. The receiver operating characteristic(ROC) curve was used to estimate the sensitivity and specificity of the Bayesian model.RESULTS: A total of 1000 eyes fundus images from diabetic patients in which 298 eyes were diagnosed as DR by two ophthalmologists. The Bayesian model was trained using four extracted textures including contrast, entropy, angular second moment and correlation using a training dataset. The Bayesian model achieved a sensitivity of 0.949 and a specificity of 0.928 in the validation dataset. The area under the ROC curve was 0.938, and the 10-fold cross validation method showed that the average accuracy rate is 93.5%.CONCLUSION: Textures extracted by grey level cooccurrence can be useful information for DR diagnosis, and a trained Bayesian model based on these textures can be an effective tool for DR screening among diabetic patients.展开更多
Based on the combination of Racah＇s group-theoretical consideration with Slater＇s wavefunction, a 91 ×91 complete energy matrix is established in tetragonal ligand field D2d for Pr3＋ ion. Thus, the Stark energ...Based on the combination of Racah＇s group-theoretical consideration with Slater＇s wavefunction, a 91 ×91 complete energy matrix is established in tetragonal ligand field D2d for Pr3＋ ion. Thus, the Stark energy-levels of Pr3＋ ions doped separately in LiYF4 and LiBiF4 crystals are calculated, and our calculations imply that the complete energy matrix method can be used as an effective tool to calculate the energy-levels of the systems doped by rare earth ions. Besides, the influence of Pr3＋ on energy-level splitting is investigated, and the similarities and the differences between the two doped crystals are demonstrated in detail by comparing their several pairs of curves and crystal field strength quantities. We see that the energy splitting patterns are similar and the crystal field interaction of LiYF4：Pr3＋ is stronger than that of LiBiF4：Pr3＋.展开更多
The mechanical properties of materials greatly depend on the microstructure morphology. The quantitative characterization of material microstructures is essential for the performance prediction and hence the material ...The mechanical properties of materials greatly depend on the microstructure morphology. The quantitative characterization of material microstructures is essential for the performance prediction and hence the material design. At present,the quantitative characterization methods mainly rely on the microstructure characterization of shape, size, distribution,and volume fraction, which related to the mechanical properties. These traditional methods have been applied for several decades and the subjectivity of human factors induces unavoidable errors. In this paper, we try to bypass the traditional operations and identify the relationship between the microstructures and the material properties by the texture of image itself directly. The statistical approach is based on gray level Co-occurrence matrix（GLCM）, allowing an objective and repeatable study on material microstructures. We first present how to identify GLCM with the optimal parameters, and then apply the method on three systems with different microstructures. The results show that GLCM can reveal the interface information and microstructures complexity with less human impact. Naturally, there is a good correlation between GLCM and the mechanical properties.展开更多
The macula is an imperative part present in our human visual system which is most responsible for clear and colour vision. For the people suffering from diabetes, the various parts of the body including the retina of ...The macula is an imperative part present in our human visual system which is most responsible for clear and colour vision. For the people suffering from diabetes, the various parts of the body including the retina of the eye are affected. These retinal damages cause swelling and other abnormalities nearby macula. The pathologies in macula due to diabetes are called Diabetic Macular oEdema (DME). It affects patients’ vision that may lead to vision loss. It can be overcome by advance identification of causes for swelling. The major causes for the swelling are neovascularization and other abnormalities occurring in the blood vessels nearby the macula. The aim of this work is to avoid vision loss by detecting the presence of abnormalities in macula in advance. The pathologies present in the abnormal images are detected by image segmentation technique viz. Fuzzy K-means algorithm. The classification is done by two different classifiers namely Cascade Neural Network and Partial Least Square which are employed to identify whether the image is normal or abnormal. The results of both the classifiers are compared with respect to classifier accuracy, sensitivity and specificity. The classifier accuracies of Cascade Neural Network and Partial Least Square are 96.84% and 94.36%, respectively. The information about the severity of the disease and the localization of pathologies are very useful to the ophthalmologist for diagnosing the disease and apply proper treatments to the patients to avoid the formation of any lesion and prevent vision loss.展开更多
文摘Since the efficiency of treatment of thyroid disorder depends on the risk of malignancy, indeterminate follicular neoplasm (FN) images should be classified. The diagnosis process has been done by visual interpretation of experienced pathologists. However, it is difficult to separate the favor benign from borderline types. Thus, this paper presents a classification approach based on 3D nuclei model to classify favor benign and borderline types of follicular thyroid adenoma (FTA) in cytological specimens. The proposed method utilized 3D gray level co-occurrence matrix (GLCM) and random forest classifier. It was applied to 22 data sets of FN images. Furthermore, the use of 3D GLCM was compared with 2D GLCM to evaluate the classification results. From experimental results, the proposed system achieved 95.45% of the classification. The use of 3D GLCM was better than 2D GLCM according to the accuracy of classification. Consequently, the proposed method probably helps a pathologist as a prescreening tool.
基金Supported by the Priming Scientific Research Foundation for the Junior Researcher in Beijing Tongren Hospital,Capital Medical University
文摘AIM: To develop an automatic tool on screening diabetic retinopathy(DR) from diabetic patients.METHODS: We extracted textures from eye fundus images of each diabetes subject using grey level co-occurrence matrix method and trained a Bayesian model based on these textures. The receiver operating characteristic(ROC) curve was used to estimate the sensitivity and specificity of the Bayesian model.RESULTS: A total of 1000 eyes fundus images from diabetic patients in which 298 eyes were diagnosed as DR by two ophthalmologists. The Bayesian model was trained using four extracted textures including contrast, entropy, angular second moment and correlation using a training dataset. The Bayesian model achieved a sensitivity of 0.949 and a specificity of 0.928 in the validation dataset. The area under the ROC curve was 0.938, and the 10-fold cross validation method showed that the average accuracy rate is 93.5%.CONCLUSION: Textures extracted by grey level cooccurrence can be useful information for DR diagnosis, and a trained Bayesian model based on these textures can be an effective tool for DR screening among diabetic patients.
基金Project supported by the National Natural Science Foundation of China(Grant Nos.10774103 and 10974138)
文摘Based on the combination of Racah＇s group-theoretical consideration with Slater＇s wavefunction, a 91 ×91 complete energy matrix is established in tetragonal ligand field D2d for Pr3＋ ion. Thus, the Stark energy-levels of Pr3＋ ions doped separately in LiYF4 and LiBiF4 crystals are calculated, and our calculations imply that the complete energy matrix method can be used as an effective tool to calculate the energy-levels of the systems doped by rare earth ions. Besides, the influence of Pr3＋ on energy-level splitting is investigated, and the similarities and the differences between the two doped crystals are demonstrated in detail by comparing their several pairs of curves and crystal field strength quantities. We see that the energy splitting patterns are similar and the crystal field interaction of LiYF4：Pr3＋ is stronger than that of LiBiF4：Pr3＋.
基金Project supported by the National Natural Science Foundation of China(Grant Nos.5147113 and 51505037)the Fundamental Research Funds for the Central Universities of Ministry of Education of China(Grant Nos.3102017zy029,310832163402,and 310832163403)
文摘The mechanical properties of materials greatly depend on the microstructure morphology. The quantitative characterization of material microstructures is essential for the performance prediction and hence the material design. At present,the quantitative characterization methods mainly rely on the microstructure characterization of shape, size, distribution,and volume fraction, which related to the mechanical properties. These traditional methods have been applied for several decades and the subjectivity of human factors induces unavoidable errors. In this paper, we try to bypass the traditional operations and identify the relationship between the microstructures and the material properties by the texture of image itself directly. The statistical approach is based on gray level Co-occurrence matrix（GLCM）, allowing an objective and repeatable study on material microstructures. We first present how to identify GLCM with the optimal parameters, and then apply the method on three systems with different microstructures. The results show that GLCM can reveal the interface information and microstructures complexity with less human impact. Naturally, there is a good correlation between GLCM and the mechanical properties.
文摘The macula is an imperative part present in our human visual system which is most responsible for clear and colour vision. For the people suffering from diabetes, the various parts of the body including the retina of the eye are affected. These retinal damages cause swelling and other abnormalities nearby macula. The pathologies in macula due to diabetes are called Diabetic Macular oEdema (DME). It affects patients’ vision that may lead to vision loss. It can be overcome by advance identification of causes for swelling. The major causes for the swelling are neovascularization and other abnormalities occurring in the blood vessels nearby the macula. The aim of this work is to avoid vision loss by detecting the presence of abnormalities in macula in advance. The pathologies present in the abnormal images are detected by image segmentation technique viz. Fuzzy K-means algorithm. The classification is done by two different classifiers namely Cascade Neural Network and Partial Least Square which are employed to identify whether the image is normal or abnormal. The results of both the classifiers are compared with respect to classifier accuracy, sensitivity and specificity. The classifier accuracies of Cascade Neural Network and Partial Least Square are 96.84% and 94.36%, respectively. The information about the severity of the disease and the localization of pathologies are very useful to the ophthalmologist for diagnosing the disease and apply proper treatments to the patients to avoid the formation of any lesion and prevent vision loss.
