Confirmation of basic technological parameters of tension levellers is the most important factor of leveling strip. Up to now, most factories have used experts’ experience to decide these parameters, without any esta...Confirmation of basic technological parameters of tension levellers is the most important factor of leveling strip. Up to now, most factories have used experts’ experience to decide these parameters, without any established rule to follow. For better quality of strip, a valid method is needed to decide technological parameters precisely and reasonably. In this paper, a method is used based on neural network and genetic algorithm. Neural network has a good ability to extract rules from work process of tension levellers. Then using neural network, which has learned from a lot of working samples, to be the evaluation of fitness, genetic algorithm could easily find the best or better technological parameters. At the end of this paper, examinations are given to show the effect of this method.展开更多
Based on the structure of chute - feed and autoleveHer, an analysis of their working principle and the verification of their practical production results have been carried out. Finally, the future investigation direet...Based on the structure of chute - feed and autoleveHer, an analysis of their working principle and the verification of their practical production results have been carried out. Finally, the future investigation direetiom of chute - feed and card autuleveller are put forward.展开更多
BACKGROUND Within the normal range,elevated alanine aminotransferase(ALT)levels are associated with an increased risk of metabolic dysfunction-associated fatty liver disease(MAFLD).AIM To investigate the associations ...BACKGROUND Within the normal range,elevated alanine aminotransferase(ALT)levels are associated with an increased risk of metabolic dysfunction-associated fatty liver disease(MAFLD).AIM To investigate the associations between repeated high-normal ALT measurements and the risk of new-onset MAFLD prospectively.METHODS A cohort of 3553 participants followed for four consecutive health examinations over 4 years was selected.The incidence rate,cumulative times,and equally and unequally weighted cumulative effects of excess high-normal ALT levels(ehALT)were measured.Cox proportional hazards regression was used to analyse the association between the cumulative effects of ehALT and the risk of new-onset MAFLD.RESULTS A total of 83.13%of participants with MAFLD had normal ALT levels.The incidence rate of MAFLD showed a linear increasing trend in the cumulative ehALT group.Compared with those in the low-normal ALT group,the multivariate adjusted hazard ratios of the equally and unequally weighted cumulative effects of ehALT were 1.651[95%confidence interval(CI):1.199-2.273]and 1.535(95%CI:1.119-2.106)in the third quartile and 1.616(95%CI:1.162-2.246)and 1.580(95%CI:1.155-2.162)in the fourth quartile,respectively.CONCLUSION Most participants with MAFLD had normal ALT levels.Long-term high-normal ALT levels were associated with a cumulative increased risk of new-onset MAFLD.展开更多
Utilizing the adopted average topographic density of 2670 kg/m^(3)in the reduction of gravity anomalies introduces errors attributed to topographic density variations,which consequently affect geoid modeling accuracy....Utilizing the adopted average topographic density of 2670 kg/m^(3)in the reduction of gravity anomalies introduces errors attributed to topographic density variations,which consequently affect geoid modeling accuracy.Furthermore,the mean gravity along the plumbline within the topography in the definition of Helmert orthometric heights is computed approximately by applying the Poincar e-Prey gravity reduction where the topographic density variations are disregarded.The Helmert orthometric heights of benchmarks are then affected by errors.These errors could be random or systematic depending on the specific geological setting of the region where the leveling network is physically established and/or the geoid model is determined.An example of systematic errors in orthometric heights can be given for large regions characterized by sediment or volcanic deposits,the density of which is substantially lower than the adopted topographic density used in Helmert's definition of heights.The same applies to geoid modeling errors.In this study,we investigate these errors in the Hong Kong territory,where topographic density is about 20%lower than the density of 2670 kg/m^(3).We use the digital rock density model to estimate the effect of topographic density variations on the geoid and orthometric heights.Our results show that this effect on the geoid and Helmert orthometric heights reach maxima of about 2.1 and 0.5 cm,respectively.Both results provide clear evidence that rock density models are essential in physical geodesy applications involving gravimetric geoid modeling and orthometric height determination despite some criticism that could be raised regarding the reliability of these density models.However,in regions dominated by sedimentary and igneous rocks,the geological information is essential in these applications because topographic densities are substantially lower than the average density of 2670 kg/m^(3),thus introducing large systematic errors in geoid and orthometric heights.展开更多
Plant polyploidy often occurs in conjunction with higher yield and superior quality.Therefore,obtaining polyploid germplasms is a significant part of breeding.The oil-tea Camellia tree is an important native woody pla...Plant polyploidy often occurs in conjunction with higher yield and superior quality.Therefore,obtaining polyploid germplasms is a significant part of breeding.The oil-tea Camellia tree is an important native woody plant that produces high-quality edible oil and includes many species of Camellia with different ploidies.However,whether higher ploidy levels in oil-tea Camellia trees are related to better traits remains unclear.In this study,the ploidy levels of 30 different oil-tea Camellia strains in three different species in the Sect.Paracamellia were determined by flow cytometry and chromosome preparation,and the phenotypic characteristics and fatty acid compositions of the fruits were examined by field observations and laboratory analyses.The correlations between the ploidy level of oil-tea Camellia and the main traits of the fruit were investigated.Our results showed that 10 Camellia lanceoleosa strains were diploid,10 Camellia meiocarpa strains were tetraploid and 10 Camellia oleifera strains were hexaploid.Hexaploid C.oleifera had larger fruit size and weight,more seeds per fruit,greater seed weight per fruit,higher oil content and greater yield per crown width than tetraploid C.meiocarpa and diploid C.lanceoleosa,but their fruit peel thickness and fresh seed rate were significantly lower,and these traits were significantly correlated with ploidy level.In addition,in terms of fatty acid composition,hexaploid C.oleifera had a higher oleic acid content than tetraploid C.meiocarpa and diploid C.lanceoleosa,but their linoleic acid,linolenic acid and arachidonic acid contents were lower.The contents of palmitic acid,stearic acid and total unsaturated fatty acids were not significantly correlated with ploidy level.In conclusion,certain correlations exist between the main characteristics of oil-tea Camellia fruit and the ploidy level,and increasing the ploidy level led to an increase in fruit yield with no effect on oil composition.The discovery of variations in the main characteristics of oil-tea Camellia fruit with different ploidies will facilitate germplasm innovation and lay a foundation for ploidy breeding and mechanistic research on fruit traits.展开更多
The nonproportional multiaxial ratchetting of cast AZ91 magnesium (Mg) alloy was examined by performing a sequence of axial-torsional cyclic tests controlled by stress with various loading paths at room temperature (R...The nonproportional multiaxial ratchetting of cast AZ91 magnesium (Mg) alloy was examined by performing a sequence of axial-torsional cyclic tests controlled by stress with various loading paths at room temperature (RT).The evolutionary characteristics and path dependence of multiaxial ratchetting were discussed.Results illustrate that the cast AZ91 Mg alloy exhibits considerable nonproportional additional softening during cyclic loading with multiple nonproportional multiaxial loading paths;multiaxial ratchetting presents strong path dependence,and axial ratchetting strains are larger under nonproportional loading paths than under uniaxial and proportional45°linear loading paths;multiaxial ratchetting becomes increasingly pronounced as the applied stress amplitude and axial mean stress increase.Moreover,stress-strain curves show a convex and symmetrical shape in axial/torsional directions.Multiaxial ratchetting exhibits quasi-shakedown after certain loading cycles.The abundant experimental data obtained in this work can be used to develop a cyclic plasticity model of cast Mg alloys.展开更多
At present,one of the methods used to determine the height of points on the Earth’s surface is Global Navigation Satellite System(GNSS)leveling.It is possible to determine the orthometric or normal height by this met...At present,one of the methods used to determine the height of points on the Earth’s surface is Global Navigation Satellite System(GNSS)leveling.It is possible to determine the orthometric or normal height by this method only if there is a geoid or quasi-geoid height model available.This paper proposes the methodology for local correction of the heights of high-order global geoid models such as EGM08,EIGEN-6C4,GECO,and XGM2019e_2159.This methodology was tested in different areas of the research field,covering various relief forms.The dependence of the change in corrected height accuracy on the input data was analyzed,and the correction was also conducted for model heights in three tidal systems:"tide free","mean tide",and"zero tide".The results show that the heights of EIGEN-6C4 model can be corrected with an accuracy of up to 1 cm for flat and foothill terrains with the dimensionality of 1°×1°,2°×2°,and 3°×3°.The EGM08 model presents an almost identical result.The EIGEN-6C4 model is best suited for mountainous relief and provides an accuracy of 1.5 cm on the 1°×1°area.The height correction accuracy of GECO and XGM2019e_2159 models is slightly poor,which has fuzziness in terms of numerical fluctuation.展开更多
Objective Pertussis cases have increased markedly since 2018 in Guangxi.The aim of this study was to evaluate antibody levels and the infection status of pertussis in the resident population.Method A total of 10,215 s...Objective Pertussis cases have increased markedly since 2018 in Guangxi.The aim of this study was to evaluate antibody levels and the infection status of pertussis in the resident population.Method A total of 10,215 serum samples from residents were collected from August-November 2018 and tested for anti-pertussis IgG and toxin IgG using the enzyme-linked immunosorbent assay(ELISA).Results Of the collected samples,1,833(17.94%)tested positive for anti-pertussis IgG,with the median concentration of 16.06 IU/mL.Antibody level<10 IU/mL accounted for more than 60%in children under 4 years of age,but declined with age,whereas the percentages of the other three levels(10-40,40-50,and≥50 IU/mL)increased almost with age(P<0.001).Moreover,7,924 samples were selected for anti-pertussis toxin IgG,of which 653(8.24%)tested positive(≥40 IU/mL)with the median concentration of 5.89 IU/mL,and 204 participants(2.56%)had recent pertussis infection(≥100 IU/mL).Among the different age groups,the highest rates of positivity and recent infection were observed at 11-20 years of age,the lowest positivity rate at 5 years of age,and the lowest recent infection rate at 4 years of age(P<0.001,P=0.005,respectively).Conclusion The survey results showed that all age groups in Guangxi lacked immunity against pertussis,which was one of the main factors contributing to the resurgence of pertussis in 2018.In addition,the prevalence of pertussis is relatively high in Guangxi,and its incidence is seriously underestimated,especially in adolescents and adults.展开更多
Allium is a complicated genus that includes approximately 1000 species.Although its morphology is well studied,the taxonomic importance of many morphological traits,including floral traits,are poorly understood.Here,w...Allium is a complicated genus that includes approximately 1000 species.Although its morphology is well studied,the taxonomic importance of many morphological traits,including floral traits,are poorly understood.Here,we examined and measured the floral characteristics of 87 accessions of 74 Allium taxa(belonging to 30 sections and nine subgenera)from Central to Eastern Asian countries.We then examined the taxonomic relationships between select flower characteristics and a phylogenetic tree based on ITS sequences.Our results confirm that floral morphology provides key taxonomic information to assess species delimitation in Allium.We found that perianth color is an important characteristic within the subg.Melanocrommyum,Polyprason,and Reticulatobulbosa.In subg.Allium,Cepa,and Rhizirideum,significant characteristics include ovary shape,perianth shape,and inner tepal apex.For species in subg.Angunium,the key taxonomic character is ovule number(only one ovule in per locule).In the subg.Allium,Cepa,Polyprason,and Reticulatobulbosa,which belong to the third evolutionary line of Allium,hood-like appendages occur in the ovary,although these do not occur in subg.Rhizirideum.Our results also indicated that the flower morphology of several species in some sections are not clearly distinguished,e.g.,sect.Sacculiferum(subg.Cepa)and sect.Tenuissima(subg.Rhizirideum).This study provides detailed photographs and descriptions of floral characteristics and information on general distributions,habitats,and phenology of the studied taxa.展开更多
While the interaction between information and disease in static networks has been extensively investigated,many studies have ignored the characteristics of network evolution.In this study,we construct a new two-layer ...While the interaction between information and disease in static networks has been extensively investigated,many studies have ignored the characteristics of network evolution.In this study,we construct a new two-layer coupling model to explore the interactions between information and disease.The upper layer describes the diffusion of disease-related information,and the lower layer represents the disease transmission.We then use power-law distributions to examine the influence of asymmetric activity levels on dynamic propagation,revealing a mapping relationship characterizing the interconnected propagation of information and diseases among partial nodes within the network.Subsequently,we derive the disease outbreak threshold by using the microscopic Markov-chain approach(MMCA).Finally,we perform extensive Monte Carlo(MC)numerical simulations to verify the accuracy of our theoretical results.Our findings indicate that the activity levels of individuals in the disease transmission layer have a more significant influence on disease transmission compared with the individual activity levels in the information diffusion layer.Moreover,reducing the damping factor can delay disease outbreaks and suppress disease transmission,while improving individual quarantine measures can contribute positively to disease control.This study provides valuable insights into policymakers for developing outbreak prevention and control strategies.展开更多
For migratory waterbirds,the quality of wintering habitat is related to spring migration and successful breeding in the next year.The availability of food resources in the habitat is critical and varies within water l...For migratory waterbirds,the quality of wintering habitat is related to spring migration and successful breeding in the next year.The availability of food resources in the habitat is critical and varies within water levels.Although the water-level fluctuations in Poyang Lake have been extremely variable interannually in recent years,the wintering waterbird populations have remained relatively stable.Hence,the mechanism of maintaining the stability is worth exploring.This study aimed to compare the distribution of vegetation and herbivorous wa-terbirds in 2015-2016 and 2016-2017,focusing on three shallow sub-lakes and one main lake are.The results showed that the emergence of tubers and the growth of Carex spp.provided a continuous food supply and habitat for wintering waterbirds with a gradual decline in the water level.Shallow sub-lakes supported almost all of the tuber-eating waterbirds(1.42-1.62×10^(5))and most geese(1.34-1.53×10^(6)).However,the main lake area,covered with Persicaria hydropiper,did not provide adequate and accessible food.This resulted in almost no distribution of tuber-eating waterbirds,with only a few geese congregating in early winter.Our results demonstrated that the shallow sub-lakes under human control provided a different environment from the main lake and are key to sustaining the successful wintering of hundreds of thousands of migratory waterbirds in Poyang Lake.Therefore,we recommend refining the anthropogenic management of the shallow sub-lakes to regulate the water level to ensure the carrying capacity of Poyang Lake.展开更多
Over the last three decades,more than half of the world's large lakes and wetlands have experienced significant shrinkage,primarily due to climate change and extensive water consumption for agriculture and other h...Over the last three decades,more than half of the world's large lakes and wetlands have experienced significant shrinkage,primarily due to climate change and extensive water consumption for agriculture and other human needs.The desiccation of lakes leads to severe environmental,economic,and social repercussions.Urmia Lake,located in northwestern Iran and representing a vital natural ecosystem,has experienced a volume reduction of over 90.0%.Our research evaluated diverse water management strategies within the Urmia Lake basin and prospects of inter-basin water transfers.This study focused on strategies to safeguard the environmental water rights of the Urmia Lake by utilizing the modeling and simulating(MODSIM)model.The model simulated changes in the lake's water volume under various scenarios.These included diverting water from incoming rivers,cutting agricultural water use by 40.0%,releasing dam water in non-agricultural seasons,treated wastewater utilization,and inter-basin transfers.Analytical hierarchy process(AHP)was utilized to analyze the simulation results.Expert opinions with AHP analysis,acted as a multi-criteria decision-making tool to evaluate the simulation and determine the optimal water supply source priority for the Urmia Lake.Our findings underscore the critical importance of reducing agricultural water consumption as the foremost step in preserving the lake.Following this,inter-basin water transfers are suggested,with a detailed consideration of the inherent challenges and limitations faced by the source watersheds.It is imperative to conduct assessments on the impacts of these transfers on the downstream users and the potential environmental risks,advocating for a diplomatic and cooperative approach with adjacent country.This study also aims to forecast the volumes of water that can be transferred under different climatic conditions—drought,normal,and wet years—to inform strategic water management planning for the Urmia Lake.According to our projection,implementing the strategic scenarios outlined could significantly augment the lake's level and volume,potentially by 3.57×109–9.38×109 m3 over the coming 10 a and 3.57×109–10.70×109 m3 in the subsequent 15 a.展开更多
A common reclamation practice for closed coal surface mines is filling them with water to form pit lakes.The creation and sustainability of these lakes are significantly affected by the stability of the corresponding ...A common reclamation practice for closed coal surface mines is filling them with water to form pit lakes.The creation and sustainability of these lakes are significantly affected by the stability of the corresponding slopes.The present study provides a general framework for analyzing the water filling’s effect on slope stability based on a new water filling index,which can indirectly consider the factors affecting the process and efficiently quantify the filling speed’s influence.The assumptions of the proposed approach are thoroughly discussed,and the range of the water filling index is identified.Furthermore,the safety factor is calculated using the finite element method with the shear strength reduction technique during the filling process for various conditions(soil properties,slope geometry,hydraulic conditions,and water filling speed).Results are presented as normalized stability charts for practical use.During the water filling,the stability gradually decreases until the reservoir reaches a critical level of 10%e40%of the total height;it then increases to even more stable conditions than the initial one.Overall,the present analysis allows for the preliminary stability evaluation of a coal mine during the formation of a pit lake and the appropriate quantification of the water filling’s effect.展开更多
The occurrence of geological hazards and the instability of geotechnical engineering structures are closely related to the time-dependent behavior of rock.However,the idealization boundary condition for constant stres...The occurrence of geological hazards and the instability of geotechnical engineering structures are closely related to the time-dependent behavior of rock.However,the idealization boundary condition for constant stress in creep or constant strain in relaxation is not usually attained in natural geological systems.Therefore,generalized relaxation tests that explore the simultaneous changes of stress and strain with time under different stress levels with constant pore-water pressure are conducted in this study.The results show that in area Ⅰ,area Ⅱ,and area Ⅲ,the stress and strain both change synchronously with time and show similar evolutionary laws as the strain-time curve for creep or the stress-time curve for relaxation.When the applied stress level surpasses the δ_(ci) or δ_(cd) threshold,the variations in stress and strain and their respective rates of change exhibit a significant increase.The radial deformation and its rate of change exhibit greater sensitivity in response to stress levels.The apparent strain deforms homogeneously at the primary stage,and subsequently,gradually localizes due to the microcrack development at the secondary stage.Ultimately,interconnection of the microcracks causes the formation of a shear-localization zone at the tertiary stage.The strain-time responses inside and outside the localization zone are characterized by local strain accumulation and inelastic unloading during the secondary and tertiary stages,respectively.The width of the shear-localization zone is found to range from 4.43 mm to 7.08 mm and increased with a longer time-to-failure.Scanning electron microscopy(SEM)reveals a dominant coalescence of intergranular cracks on the fracture surface,and the degree of physiochemical deterioration caused by water-rock interaction is more severe under a longer lifetime.The brittle sandstone’s time-dependent deformation is essentially controlled by microcrack development during generalized relaxation,and its expectancy-life is determined by its initial microstructural state and the rheological path.展开更多
In this study,we estimate the absolute vertical land motions at three tidal stations with collocated Global Navigation Satellite System(GNSS)receivers over French Polynesia during the period 2007-2020,and obtain,as an...In this study,we estimate the absolute vertical land motions at three tidal stations with collocated Global Navigation Satellite System(GNSS)receivers over French Polynesia during the period 2007-2020,and obtain,as ancillary results,estimates of the absolute changes in sea level at the same locations.To verify our processing approach to determining vertical motion,we first modeled vertical motion at the International GNSS Service(IGS)THTI station located in the capital island of Tahiti and compared our estimate with previous independent determinations,with a good agreement.We obtained the following estimates for the vertical land motions at the tide gauges:Tubuai island,Austral Archipelago-0.92±0.17 mm/yr,Vairao village,Tahiti Iti:-0.49±0.39 mm/yr,Rikitea,Gambier Archipelago-0.43±0.17 mm/yr.The absolute variations of the sea level are:Tubuai island,Austral Archipelago 5.25±0.60 mm/yr,Vairao village,Tahiti Iti:3.62±0.52 mm/yr,Rikitea,Gambier Archipelago 1.52±0.23 mm/yr.We discuss these absolute values in light of the values obtained from altimetric measurements and other means in French Polynesia.展开更多
This study quantified the regional damages resulting from temperature and sea level changes using the Regional Integrated of Climate and Economy(RICE)model,as well as the effects of enabling and disabling the climate ...This study quantified the regional damages resulting from temperature and sea level changes using the Regional Integrated of Climate and Economy(RICE)model,as well as the effects of enabling and disabling the climate impact module on future emission pathways.Results highlight varied damages depending on regional economic development and locations.Specifically,China and Africa could suffer the most serious comprehensive damages caused by temperature change and sea level rise,followed by India,other developing Asian countries(OthAsia),and other high-income countries(OHI).The comprehensive damage fractions for China and Africa are projected to be 15.1%and 12.5%of gross domestic product(GDP)in 2195,with corresponding cumulative damages of 124.0 trillion and 87.3 trillion United States dollars(USD)from 2005 to 2195,respectively.Meanwhile,the comprehensive damage fractions in Japan,Eurasia,and Russia are smaller and projected to be lower than 5.6%of GDP in 2195,with cumulative damages of 6.8 trillion,4.2 trillion,and 3.3 trillion USD,respectively.Additionally,coastal regions like Africa,the European Union(EU),and OHI show comparable damages for sea level rise and temperature change.In China,however,sea level-induced damages are projected to exceed those from temperature changes.Moreover,this study indicates that switching the damage modules on or off affects the regional and global emission trajectories,but the magnitude is relatively small.By 2195,global emissions under the experiments with all of the damage modules switched off,only the sea level damage module switched on,and only the temperature damage module switched on,were 3.5%,2.3%and 1.2%higher than those with all of the damage modules switched on,respectively.展开更多
The corona discharge from transmission lines in high-altitude areas is more severe than at lower altitudes. The radio interference caused thereby is a key factor to be considered when designing transmission lines. To ...The corona discharge from transmission lines in high-altitude areas is more severe than at lower altitudes. The radio interference caused thereby is a key factor to be considered when designing transmission lines. To study the influence of altitude on negative corona characteristics, an experimental platform comprising a movable small corona cage was established: experiments were conducted at four altitudes in the range of 1120-4320 m, and data on the corona current pulse and radio interference level of 0.8-mm diameter fine copper wire under different negative voltages were collected. The experimental results show that the average amplitude, repetition frequency and average current of the corona current pulse increase with increasing altitude. The dispersion of pulse amplitude increases with increase in altitude, while the randomness of the pulse interval decreases continuously. Taking the average current as an intermediate variable,the relationship between radio interference level and altitude is obtained. The result of this research has some significance for understanding the corona discharge characteristics of ultra-highvoltage lines.展开更多
The in vitro digestion models mimicking the gastrointestinal(GI)tract of general population and lipid indigestion patients(with lower levels of bile salts or pancreatic lipase)were selected to investigate whether diac...The in vitro digestion models mimicking the gastrointestinal(GI)tract of general population and lipid indigestion patients(with lower levels of bile salts or pancreatic lipase)were selected to investigate whether diacylglycerols(DAGs)are potential good lipid sources for these patients.Linseed oil-based DAG(LD)and linseed oil(LT)were selected.LD-based emulsion((83.74±1.23)%)had higher lipolysis degree than LT-based emulsion((74.47±1.16)%)when monitoring the GI tract of normal population as previously reported.Indigestion conditions seriously decreased the digestive degree of LT-based emulsion((40.23±2.48)%-(66.50±3.70)%)while showed less influence on LD-based emulsion((64.18±2.41)%-(81.85±3.45)%).As opposed to LT-based emulsion,LD-based emulsion exhibited preference for releasing unsaturated fatty acids(especially oleic acid andα-linolenic acid)due to their different glycerolipid compositions.LD-based emulsion showed potential for providing lipids and nutrients(including essential fatty acids)for lipid indigestion patients.展开更多
文摘Confirmation of basic technological parameters of tension levellers is the most important factor of leveling strip. Up to now, most factories have used experts’ experience to decide these parameters, without any established rule to follow. For better quality of strip, a valid method is needed to decide technological parameters precisely and reasonably. In this paper, a method is used based on neural network and genetic algorithm. Neural network has a good ability to extract rules from work process of tension levellers. Then using neural network, which has learned from a lot of working samples, to be the evaluation of fitness, genetic algorithm could easily find the best or better technological parameters. At the end of this paper, examinations are given to show the effect of this method.
文摘Based on the structure of chute - feed and autoleveHer, an analysis of their working principle and the verification of their practical production results have been carried out. Finally, the future investigation direetiom of chute - feed and card autuleveller are put forward.
基金National Natural Science Foundation of China,No.72101236China Postdoctoral Science Foundation,No.2022M722900+1 种基金Collaborative Innovation Project of Zhengzhou City,No.XTCX2023006Nursing Team Project of the First Affiliated Hospital of Zhengzhou University,No.HLKY2023005.
文摘BACKGROUND Within the normal range,elevated alanine aminotransferase(ALT)levels are associated with an increased risk of metabolic dysfunction-associated fatty liver disease(MAFLD).AIM To investigate the associations between repeated high-normal ALT measurements and the risk of new-onset MAFLD prospectively.METHODS A cohort of 3553 participants followed for four consecutive health examinations over 4 years was selected.The incidence rate,cumulative times,and equally and unequally weighted cumulative effects of excess high-normal ALT levels(ehALT)were measured.Cox proportional hazards regression was used to analyse the association between the cumulative effects of ehALT and the risk of new-onset MAFLD.RESULTS A total of 83.13%of participants with MAFLD had normal ALT levels.The incidence rate of MAFLD showed a linear increasing trend in the cumulative ehALT group.Compared with those in the low-normal ALT group,the multivariate adjusted hazard ratios of the equally and unequally weighted cumulative effects of ehALT were 1.651[95%confidence interval(CI):1.199-2.273]and 1.535(95%CI:1.119-2.106)in the third quartile and 1.616(95%CI:1.162-2.246)and 1.580(95%CI:1.155-2.162)in the fourth quartile,respectively.CONCLUSION Most participants with MAFLD had normal ALT levels.Long-term high-normal ALT levels were associated with a cumulative increased risk of new-onset MAFLD.
基金supported by the Hong Kong GRF RGC project 15217222:“Modernization of the leveling network in the Hong Kong territories”。
文摘Utilizing the adopted average topographic density of 2670 kg/m^(3)in the reduction of gravity anomalies introduces errors attributed to topographic density variations,which consequently affect geoid modeling accuracy.Furthermore,the mean gravity along the plumbline within the topography in the definition of Helmert orthometric heights is computed approximately by applying the Poincar e-Prey gravity reduction where the topographic density variations are disregarded.The Helmert orthometric heights of benchmarks are then affected by errors.These errors could be random or systematic depending on the specific geological setting of the region where the leveling network is physically established and/or the geoid model is determined.An example of systematic errors in orthometric heights can be given for large regions characterized by sediment or volcanic deposits,the density of which is substantially lower than the adopted topographic density used in Helmert's definition of heights.The same applies to geoid modeling errors.In this study,we investigate these errors in the Hong Kong territory,where topographic density is about 20%lower than the density of 2670 kg/m^(3).We use the digital rock density model to estimate the effect of topographic density variations on the geoid and orthometric heights.Our results show that this effect on the geoid and Helmert orthometric heights reach maxima of about 2.1 and 0.5 cm,respectively.Both results provide clear evidence that rock density models are essential in physical geodesy applications involving gravimetric geoid modeling and orthometric height determination despite some criticism that could be raised regarding the reliability of these density models.However,in regions dominated by sedimentary and igneous rocks,the geological information is essential in these applications because topographic densities are substantially lower than the average density of 2670 kg/m^(3),thus introducing large systematic errors in geoid and orthometric heights.
基金supported by the Special Funds for Construction of Innovative Provinces in Hunan Province,China(2021NK1007)the Hunan Provincial Innovation Foundation for Postgraduate,China(CX20230779)the Scientific Innovation Fund for Post-graduates of Central South University of Forestry and Technology,China(2023CX01009)。
文摘Plant polyploidy often occurs in conjunction with higher yield and superior quality.Therefore,obtaining polyploid germplasms is a significant part of breeding.The oil-tea Camellia tree is an important native woody plant that produces high-quality edible oil and includes many species of Camellia with different ploidies.However,whether higher ploidy levels in oil-tea Camellia trees are related to better traits remains unclear.In this study,the ploidy levels of 30 different oil-tea Camellia strains in three different species in the Sect.Paracamellia were determined by flow cytometry and chromosome preparation,and the phenotypic characteristics and fatty acid compositions of the fruits were examined by field observations and laboratory analyses.The correlations between the ploidy level of oil-tea Camellia and the main traits of the fruit were investigated.Our results showed that 10 Camellia lanceoleosa strains were diploid,10 Camellia meiocarpa strains were tetraploid and 10 Camellia oleifera strains were hexaploid.Hexaploid C.oleifera had larger fruit size and weight,more seeds per fruit,greater seed weight per fruit,higher oil content and greater yield per crown width than tetraploid C.meiocarpa and diploid C.lanceoleosa,but their fruit peel thickness and fresh seed rate were significantly lower,and these traits were significantly correlated with ploidy level.In addition,in terms of fatty acid composition,hexaploid C.oleifera had a higher oleic acid content than tetraploid C.meiocarpa and diploid C.lanceoleosa,but their linoleic acid,linolenic acid and arachidonic acid contents were lower.The contents of palmitic acid,stearic acid and total unsaturated fatty acids were not significantly correlated with ploidy level.In conclusion,certain correlations exist between the main characteristics of oil-tea Camellia fruit and the ploidy level,and increasing the ploidy level led to an increase in fruit yield with no effect on oil composition.The discovery of variations in the main characteristics of oil-tea Camellia fruit with different ploidies will facilitate germplasm innovation and lay a foundation for ploidy breeding and mechanistic research on fruit traits.
基金financially supported by the National Natural Science Foundation of China(Nos.12192210 and12192214)the Independent Project of State Key Laboratory of Traction Power(No.2022TPL-T05)。
文摘The nonproportional multiaxial ratchetting of cast AZ91 magnesium (Mg) alloy was examined by performing a sequence of axial-torsional cyclic tests controlled by stress with various loading paths at room temperature (RT).The evolutionary characteristics and path dependence of multiaxial ratchetting were discussed.Results illustrate that the cast AZ91 Mg alloy exhibits considerable nonproportional additional softening during cyclic loading with multiple nonproportional multiaxial loading paths;multiaxial ratchetting presents strong path dependence,and axial ratchetting strains are larger under nonproportional loading paths than under uniaxial and proportional45°linear loading paths;multiaxial ratchetting becomes increasingly pronounced as the applied stress amplitude and axial mean stress increase.Moreover,stress-strain curves show a convex and symmetrical shape in axial/torsional directions.Multiaxial ratchetting exhibits quasi-shakedown after certain loading cycles.The abundant experimental data obtained in this work can be used to develop a cyclic plasticity model of cast Mg alloys.
基金the International Center for Global Earth Models(ICGEM)for the height anomaly and gravity anomaly data and Bureau Gravimetrique International(BGI)for free-air gravity anomaly data from the World Gravity Map project(WGM2012)The authors are grateful to Głowny Urza˛d Geodezji i Kartografii of Poland for the height anomaly data of the quasi-geoid PL-geoid2021.
文摘At present,one of the methods used to determine the height of points on the Earth’s surface is Global Navigation Satellite System(GNSS)leveling.It is possible to determine the orthometric or normal height by this method only if there is a geoid or quasi-geoid height model available.This paper proposes the methodology for local correction of the heights of high-order global geoid models such as EGM08,EIGEN-6C4,GECO,and XGM2019e_2159.This methodology was tested in different areas of the research field,covering various relief forms.The dependence of the change in corrected height accuracy on the input data was analyzed,and the correction was also conducted for model heights in three tidal systems:"tide free","mean tide",and"zero tide".The results show that the heights of EIGEN-6C4 model can be corrected with an accuracy of up to 1 cm for flat and foothill terrains with the dimensionality of 1°×1°,2°×2°,and 3°×3°.The EGM08 model presents an almost identical result.The EIGEN-6C4 model is best suited for mountainous relief and provides an accuracy of 1.5 cm on the 1°×1°area.The height correction accuracy of GECO and XGM2019e_2159 models is slightly poor,which has fuzziness in terms of numerical fluctuation.
基金approved by the Ethics Committee of the Guangxi Zhuang Autonomous Region Center for Disease Control and Prevention(GXIRB 2018-0005),and the participants signed informed consent forms.
文摘Objective Pertussis cases have increased markedly since 2018 in Guangxi.The aim of this study was to evaluate antibody levels and the infection status of pertussis in the resident population.Method A total of 10,215 serum samples from residents were collected from August-November 2018 and tested for anti-pertussis IgG and toxin IgG using the enzyme-linked immunosorbent assay(ELISA).Results Of the collected samples,1,833(17.94%)tested positive for anti-pertussis IgG,with the median concentration of 16.06 IU/mL.Antibody level<10 IU/mL accounted for more than 60%in children under 4 years of age,but declined with age,whereas the percentages of the other three levels(10-40,40-50,and≥50 IU/mL)increased almost with age(P<0.001).Moreover,7,924 samples were selected for anti-pertussis toxin IgG,of which 653(8.24%)tested positive(≥40 IU/mL)with the median concentration of 5.89 IU/mL,and 204 participants(2.56%)had recent pertussis infection(≥100 IU/mL).Among the different age groups,the highest rates of positivity and recent infection were observed at 11-20 years of age,the lowest positivity rate at 5 years of age,and the lowest recent infection rate at 4 years of age(P<0.001,P=0.005,respectively).Conclusion The survey results showed that all age groups in Guangxi lacked immunity against pertussis,which was one of the main factors contributing to the resurgence of pertussis in 2018.In addition,the prevalence of pertussis is relatively high in Guangxi,and its incidence is seriously underestimated,especially in adolescents and adults.
基金supported by research grants from the Korea National Arboretum (Grant No. KNA1-1-26, 20-1)the Mid-level professor Financial Program at Changwon National University in 2023
文摘Allium is a complicated genus that includes approximately 1000 species.Although its morphology is well studied,the taxonomic importance of many morphological traits,including floral traits,are poorly understood.Here,we examined and measured the floral characteristics of 87 accessions of 74 Allium taxa(belonging to 30 sections and nine subgenera)from Central to Eastern Asian countries.We then examined the taxonomic relationships between select flower characteristics and a phylogenetic tree based on ITS sequences.Our results confirm that floral morphology provides key taxonomic information to assess species delimitation in Allium.We found that perianth color is an important characteristic within the subg.Melanocrommyum,Polyprason,and Reticulatobulbosa.In subg.Allium,Cepa,and Rhizirideum,significant characteristics include ovary shape,perianth shape,and inner tepal apex.For species in subg.Angunium,the key taxonomic character is ovule number(only one ovule in per locule).In the subg.Allium,Cepa,Polyprason,and Reticulatobulbosa,which belong to the third evolutionary line of Allium,hood-like appendages occur in the ovary,although these do not occur in subg.Rhizirideum.Our results also indicated that the flower morphology of several species in some sections are not clearly distinguished,e.g.,sect.Sacculiferum(subg.Cepa)and sect.Tenuissima(subg.Rhizirideum).This study provides detailed photographs and descriptions of floral characteristics and information on general distributions,habitats,and phenology of the studied taxa.
基金Project supported by the National Natural Science Foundation of China (Grant Nos. 72174121 and 71774111)the Program for Professor of Special Appointment (Eastern Scholar) at Shanghai Institutions of Higher Learningthe Project for the Natural Science Foundation of Shanghai, China (Grant No. 21ZR1444100)
文摘While the interaction between information and disease in static networks has been extensively investigated,many studies have ignored the characteristics of network evolution.In this study,we construct a new two-layer coupling model to explore the interactions between information and disease.The upper layer describes the diffusion of disease-related information,and the lower layer represents the disease transmission.We then use power-law distributions to examine the influence of asymmetric activity levels on dynamic propagation,revealing a mapping relationship characterizing the interconnected propagation of information and diseases among partial nodes within the network.Subsequently,we derive the disease outbreak threshold by using the microscopic Markov-chain approach(MMCA).Finally,we perform extensive Monte Carlo(MC)numerical simulations to verify the accuracy of our theoretical results.Our findings indicate that the activity levels of individuals in the disease transmission layer have a more significant influence on disease transmission compared with the individual activity levels in the information diffusion layer.Moreover,reducing the damping factor can delay disease outbreaks and suppress disease transmission,while improving individual quarantine measures can contribute positively to disease control.This study provides valuable insights into policymakers for developing outbreak prevention and control strategies.
基金funded by the Poyang Lake Water Conservancy Project Office of the Department of Water Resources,Jiangxi Province,China(KT201537)the National Natural Science Foundation of China(Grant No.32360285)the National Geographic Air and Water Con-servation Fund(GEFC07-15).
文摘For migratory waterbirds,the quality of wintering habitat is related to spring migration and successful breeding in the next year.The availability of food resources in the habitat is critical and varies within water levels.Although the water-level fluctuations in Poyang Lake have been extremely variable interannually in recent years,the wintering waterbird populations have remained relatively stable.Hence,the mechanism of maintaining the stability is worth exploring.This study aimed to compare the distribution of vegetation and herbivorous wa-terbirds in 2015-2016 and 2016-2017,focusing on three shallow sub-lakes and one main lake are.The results showed that the emergence of tubers and the growth of Carex spp.provided a continuous food supply and habitat for wintering waterbirds with a gradual decline in the water level.Shallow sub-lakes supported almost all of the tuber-eating waterbirds(1.42-1.62×10^(5))and most geese(1.34-1.53×10^(6)).However,the main lake area,covered with Persicaria hydropiper,did not provide adequate and accessible food.This resulted in almost no distribution of tuber-eating waterbirds,with only a few geese congregating in early winter.Our results demonstrated that the shallow sub-lakes under human control provided a different environment from the main lake and are key to sustaining the successful wintering of hundreds of thousands of migratory waterbirds in Poyang Lake.Therefore,we recommend refining the anthropogenic management of the shallow sub-lakes to regulate the water level to ensure the carrying capacity of Poyang Lake.
文摘Over the last three decades,more than half of the world's large lakes and wetlands have experienced significant shrinkage,primarily due to climate change and extensive water consumption for agriculture and other human needs.The desiccation of lakes leads to severe environmental,economic,and social repercussions.Urmia Lake,located in northwestern Iran and representing a vital natural ecosystem,has experienced a volume reduction of over 90.0%.Our research evaluated diverse water management strategies within the Urmia Lake basin and prospects of inter-basin water transfers.This study focused on strategies to safeguard the environmental water rights of the Urmia Lake by utilizing the modeling and simulating(MODSIM)model.The model simulated changes in the lake's water volume under various scenarios.These included diverting water from incoming rivers,cutting agricultural water use by 40.0%,releasing dam water in non-agricultural seasons,treated wastewater utilization,and inter-basin transfers.Analytical hierarchy process(AHP)was utilized to analyze the simulation results.Expert opinions with AHP analysis,acted as a multi-criteria decision-making tool to evaluate the simulation and determine the optimal water supply source priority for the Urmia Lake.Our findings underscore the critical importance of reducing agricultural water consumption as the foremost step in preserving the lake.Following this,inter-basin water transfers are suggested,with a detailed consideration of the inherent challenges and limitations faced by the source watersheds.It is imperative to conduct assessments on the impacts of these transfers on the downstream users and the potential environmental risks,advocating for a diplomatic and cooperative approach with adjacent country.This study also aims to forecast the volumes of water that can be transferred under different climatic conditions—drought,normal,and wet years—to inform strategic water management planning for the Urmia Lake.According to our projection,implementing the strategic scenarios outlined could significantly augment the lake's level and volume,potentially by 3.57×109–9.38×109 m3 over the coming 10 a and 3.57×109–10.70×109 m3 in the subsequent 15 a.
基金This work has received funding from the European Union’s Research Fund for Coal and Steel under the projects RAFF grant agreement No.847299 and POMHAZ grant agreement No.101057326.Financial assistance by the European Commission is much appreciated.
文摘A common reclamation practice for closed coal surface mines is filling them with water to form pit lakes.The creation and sustainability of these lakes are significantly affected by the stability of the corresponding slopes.The present study provides a general framework for analyzing the water filling’s effect on slope stability based on a new water filling index,which can indirectly consider the factors affecting the process and efficiently quantify the filling speed’s influence.The assumptions of the proposed approach are thoroughly discussed,and the range of the water filling index is identified.Furthermore,the safety factor is calculated using the finite element method with the shear strength reduction technique during the filling process for various conditions(soil properties,slope geometry,hydraulic conditions,and water filling speed).Results are presented as normalized stability charts for practical use.During the water filling,the stability gradually decreases until the reservoir reaches a critical level of 10%e40%of the total height;it then increases to even more stable conditions than the initial one.Overall,the present analysis allows for the preliminary stability evaluation of a coal mine during the formation of a pit lake and the appropriate quantification of the water filling’s effect.
基金financially supported by the National Natural Science Foundation of China(Grant Nos.52304099,52172625)Shenzhen Science and Technology Program(Grant No.RCYX20221008092903013).
文摘The occurrence of geological hazards and the instability of geotechnical engineering structures are closely related to the time-dependent behavior of rock.However,the idealization boundary condition for constant stress in creep or constant strain in relaxation is not usually attained in natural geological systems.Therefore,generalized relaxation tests that explore the simultaneous changes of stress and strain with time under different stress levels with constant pore-water pressure are conducted in this study.The results show that in area Ⅰ,area Ⅱ,and area Ⅲ,the stress and strain both change synchronously with time and show similar evolutionary laws as the strain-time curve for creep or the stress-time curve for relaxation.When the applied stress level surpasses the δ_(ci) or δ_(cd) threshold,the variations in stress and strain and their respective rates of change exhibit a significant increase.The radial deformation and its rate of change exhibit greater sensitivity in response to stress levels.The apparent strain deforms homogeneously at the primary stage,and subsequently,gradually localizes due to the microcrack development at the secondary stage.Ultimately,interconnection of the microcracks causes the formation of a shear-localization zone at the tertiary stage.The strain-time responses inside and outside the localization zone are characterized by local strain accumulation and inelastic unloading during the secondary and tertiary stages,respectively.The width of the shear-localization zone is found to range from 4.43 mm to 7.08 mm and increased with a longer time-to-failure.Scanning electron microscopy(SEM)reveals a dominant coalescence of intergranular cracks on the fracture surface,and the degree of physiochemical deterioration caused by water-rock interaction is more severe under a longer lifetime.The brittle sandstone’s time-dependent deformation is essentially controlled by microcrack development during generalized relaxation,and its expectancy-life is determined by its initial microstructural state and the rheological path.
基金the University of French Polynesiafunding by several successive“Decision Aide a la Recherche”(DAR)grants to the Geodesy Observatory of Tahiti from the French Space Agency(CNES)+2 种基金fundings from the local government of French Polynesia(Observatoire Polynesien du Rechauffement Climatique)funding by“National Natural Science Foundation of China”(Grand No.41931075)funding by“the Fundamental Research Funds for the Central Universities"(Grand No.2042022kf1198)。
文摘In this study,we estimate the absolute vertical land motions at three tidal stations with collocated Global Navigation Satellite System(GNSS)receivers over French Polynesia during the period 2007-2020,and obtain,as ancillary results,estimates of the absolute changes in sea level at the same locations.To verify our processing approach to determining vertical motion,we first modeled vertical motion at the International GNSS Service(IGS)THTI station located in the capital island of Tahiti and compared our estimate with previous independent determinations,with a good agreement.We obtained the following estimates for the vertical land motions at the tide gauges:Tubuai island,Austral Archipelago-0.92±0.17 mm/yr,Vairao village,Tahiti Iti:-0.49±0.39 mm/yr,Rikitea,Gambier Archipelago-0.43±0.17 mm/yr.The absolute variations of the sea level are:Tubuai island,Austral Archipelago 5.25±0.60 mm/yr,Vairao village,Tahiti Iti:3.62±0.52 mm/yr,Rikitea,Gambier Archipelago 1.52±0.23 mm/yr.We discuss these absolute values in light of the values obtained from altimetric measurements and other means in French Polynesia.
基金funded by the National Natu-ral Science Foundation of China(Grant No.42075044 and No.41975112)a project supported by the Innovation Group Project of the Southern Marine Science and Engineering Guangdong Laboratory(Zhuhai)(Grant No.311022006).
文摘This study quantified the regional damages resulting from temperature and sea level changes using the Regional Integrated of Climate and Economy(RICE)model,as well as the effects of enabling and disabling the climate impact module on future emission pathways.Results highlight varied damages depending on regional economic development and locations.Specifically,China and Africa could suffer the most serious comprehensive damages caused by temperature change and sea level rise,followed by India,other developing Asian countries(OthAsia),and other high-income countries(OHI).The comprehensive damage fractions for China and Africa are projected to be 15.1%and 12.5%of gross domestic product(GDP)in 2195,with corresponding cumulative damages of 124.0 trillion and 87.3 trillion United States dollars(USD)from 2005 to 2195,respectively.Meanwhile,the comprehensive damage fractions in Japan,Eurasia,and Russia are smaller and projected to be lower than 5.6%of GDP in 2195,with cumulative damages of 6.8 trillion,4.2 trillion,and 3.3 trillion USD,respectively.Additionally,coastal regions like Africa,the European Union(EU),and OHI show comparable damages for sea level rise and temperature change.In China,however,sea level-induced damages are projected to exceed those from temperature changes.Moreover,this study indicates that switching the damage modules on or off affects the regional and global emission trajectories,but the magnitude is relatively small.By 2195,global emissions under the experiments with all of the damage modules switched off,only the sea level damage module switched on,and only the temperature damage module switched on,were 3.5%,2.3%and 1.2%higher than those with all of the damage modules switched on,respectively.
基金supported by the Science and Technology Project of State Grid Corporation of China (No.5200202155587A-0-5-GC)。
文摘The corona discharge from transmission lines in high-altitude areas is more severe than at lower altitudes. The radio interference caused thereby is a key factor to be considered when designing transmission lines. To study the influence of altitude on negative corona characteristics, an experimental platform comprising a movable small corona cage was established: experiments were conducted at four altitudes in the range of 1120-4320 m, and data on the corona current pulse and radio interference level of 0.8-mm diameter fine copper wire under different negative voltages were collected. The experimental results show that the average amplitude, repetition frequency and average current of the corona current pulse increase with increasing altitude. The dispersion of pulse amplitude increases with increase in altitude, while the randomness of the pulse interval decreases continuously. Taking the average current as an intermediate variable,the relationship between radio interference level and altitude is obtained. The result of this research has some significance for understanding the corona discharge characteristics of ultra-highvoltage lines.
基金National Key R&D Program of China(2022YFC2805100)National Science Fund for Key Program of National Natural Science Foundation of China(31930084)+3 种基金National Science Fund for Distinguished Young Scholars of China(31725022)China Agriculture Research System(CARS-18-ZJ0503)Guangdong Provincial Key R&D Programme(2022B0202010002)Science and Technology Innovation Project of Foshan City(FS0AAKJ919-4402-0013)。
文摘The in vitro digestion models mimicking the gastrointestinal(GI)tract of general population and lipid indigestion patients(with lower levels of bile salts or pancreatic lipase)were selected to investigate whether diacylglycerols(DAGs)are potential good lipid sources for these patients.Linseed oil-based DAG(LD)and linseed oil(LT)were selected.LD-based emulsion((83.74±1.23)%)had higher lipolysis degree than LT-based emulsion((74.47±1.16)%)when monitoring the GI tract of normal population as previously reported.Indigestion conditions seriously decreased the digestive degree of LT-based emulsion((40.23±2.48)%-(66.50±3.70)%)while showed less influence on LD-based emulsion((64.18±2.41)%-(81.85±3.45)%).As opposed to LT-based emulsion,LD-based emulsion exhibited preference for releasing unsaturated fatty acids(especially oleic acid andα-linolenic acid)due to their different glycerolipid compositions.LD-based emulsion showed potential for providing lipids and nutrients(including essential fatty acids)for lipid indigestion patients.