Logistic Regression Analysis on the Correlation between Physical Diseases and Life Events and Depression in the Elderly

[Objectives]This study was conducted to explore the effects of physical diseases and life events on depression among urban elderly people.[Methods]Five hundred urban elderly people in Shiyan City were selected using a convenient sampling method to investigate and diagnose depression using the Geriatric Mental State Schedule and its accompanying computer diagnostic system.The Minimum Data Set(MDS)and related factor survey form were used to investigate physical diseases and life events,and statistical analysis was conducted using methods such as logistic regression analysis and factor analysis.[Results]The prevalence rates of angina,stroke,or partial paralysis,migraine,vision problems,hyperthyroidism or hypothyroidism,as well as the number of physical diseases were significantly higher in elderly depression patients than in objects free of depression.Stroke or partial paralysis[OR(95%CI)=6.389(1.684,24.237)],emotional trauma events[OR(95%CI)=1.438(1.069,1.934)]and adverse health and economic events[OR(95%CI)=1.652(1.099,2.483)]were risk factors for late life depression(LLD).[Conclusions]Some physical diseases and life events may affect the onset process of depression in urban elderly people,and various measures need to be taken to reduce the risk of physical diseases and life events on depression.

Coping as a Mechanism Linking Stressful Life Events and Mental Health Problems in Adolescents

Objective Although stressful life events represent an etiologic factor of mental health problems in adolescents, few studies have been conducted to address mechanisms linking the stress-psychopathology relation. The present study was designed to examine coping as a mediate factor on the relationship between stressful life events and symptoms of anxiety and depression. Methods The participants were 13 512 students from eight cities of China, who participated in a school-based survey. Data were collected by a questionnaire comprising coping, stressful life events, anxiety, and depressive symptoms. As a model, a series of regression equations were used to examine whether coping mediated the association between stressful life events and symptoms of anxiety and depression. Results Each dimension of stressful life events showed significant correlation with anxiety, depression and coping （all P〈0.001）. In the model to analyze mediate effects, all standardized coefficients （β） were significant （all P〈0.01）, indicating marked mediator effects. Furthermore, negative coping might account for more mediate effects than positive coping on this relationship. Conclusion Coping partially mediated the relationship between stressful life events and mental health during adolescence. This study highlighted an important public health priority for preventive interventions targeting stress-related psychopathology, and for further promoting adolescents＇ mental health.

Highly Secure Residents Life Event Management System Based on Blockchain by Hyperledger Fabric

This article describes the design and implementation of Residents Life Event Management System (hereinafter called as RLEMS) with high level reliability and security by blockchain technology. The data access environment provided by blockchain is highly secure and trustworthy. In Blockchain system, some data fragments are grouped into one piece called as blocks, and all blocks are connected to create a chain of blocks in database. When blocks are connected, hash value is used to connect blocks properly. Blockchain technology enables highly secure and reliable data management system under relatively poor ICT environment. For example, developing countries such as African countries do not have sufficient ICT environment. Therefore adopting blockchain technology is suitable for such countries. Based on this consideration, we have started to build RLEMS on the blockchain system. In previous work, we used the MultiChain as a blockchain platform. However, as MultiChain platform is mainly for private blockchain system, it is not suitable for government-level data management system. Therefore, we tried to use another blockchain framework. We selected Hyperledger Fabric which was developed by Linux Foundation. It enables to implement all styles of blockchain system. This article describes the design and implementation of RLEMS by using Hyperledger Fabric. Furthermore, to provide the best user experience, we also built the web application interface with Java web application framework named PrimeFace. The implementation of a prototype revealed that the Hyperledger Fabric blockchain technology is more suitable than MultiChain.

An Examination of the Validity of the Differentiation-of-Self Hypothesis and Its Mechanism Related to Negative Life Event Aversion among Japanese University Students

This study examined the validity of the differentiation-of-self hypothesis for Japanese university students, and its mechanism in relation to negative life event aversion. Although the differentiation-of-self hypothesis is accepted as one of the basic hypotheses in the clinical field of family therapy in Japan, empirical studies on the subject are scarce. Further, there are few studies, internationally, on its mechanism. A questionnaire survey was conducted with university students (n = 250) to measure their differentiation of self, maladaptive states, and negative life event aversion. Compared to the better-differentiated group, the less-differentiated group had higher scores both for maladaptive states—somatic symptoms (t(223) = -2.70, p = 0.008), social dysfunction (t(211.00) = -3.30, p = 0.001), and severe depression (t(208.78) = -4.08, p < 0.001)—and negative life event aversion—interpersonal domain (t(223) = -3.96, p < 0.001) and achievement domain (t(223) = -3.83, p < 0.001). The results supported the validity of the differentiation-of-self hypothesis for Japanese university students, and that cognitive tendencies toward negative life events may be part of the mechanism for less-differentiated individuals’ subsequent vulnerability. This suggests the effectiveness of cognitive interventions.

Causation mechanism of coal miners' human errors in the perspective of life events

In order to effectively decrease the safety accidents caused by coal miners’human errors,this paper probes into the causality between human errors and life events,coping,psychological stress,psychological function,physiological function based on life events’vital influence on human errors,establishing causation mechanism model of coal miners’human errors in the perspective of life events by the researching method of structural equation.The research findings show that life events have significantly positive influence on human errors,with a influential effect value of 0.7945 and a influential effect path of‘‘life events—psychological stress—psychological function—physiological function—human errors’’and‘‘life events—psychological stress—physiological function—human errors’’.

The effect of life events, personality and coping strategies on depressive of undergraduates

AIM:To study the effect of life events,personality and coping strategies on depression of undergraduates.METHOD:Fifteen hundred students were selected in the three schoolyards of Central South University.Life Events Scale,Coping Strategies Scale,Eysenck Personality Questionnaire(EPQ)and Self rating Depressive Scale (SDS) were used to assess all samples.RESULTS:The score of SDS was (42±8).The life events came from relationship of person,stress of study,loss,punishment,health and adaptation,love and family were higher in the SDS group of higher score,which the SDS group of higher score took more negative coping strategies than the normal score.CONCLUSION:The rate of depression was higher in undergraduates,which need more attention on it.More life events, introversive instability personality and negative coping strategies may be the main risk factors that caused depression.

Psychological impact of chronic hepatitis C:Comparison with other stressful life events and chronic diseases

瞄准：检验长期的丙肝(CHC ) 的心理影响在 CHC 病人的一个大队的诊断作为与带威胁生活的复杂并发症的风险的另外的紧张的生活事件和慢性病相比。方法：有补偿 CHC 的 185 个门诊病人被问到自我等级，用 100 公里 visual 类似物规模(管) ，应力的度由听说 CHC 诊断和他们的疾病的察觉的严厉引起了。诊断相关的应力与四个另外的紧张的生活事件相比并且察觉了严厉与四另外的普通慢性病相比的 CHC。结果：听说 CHC 诊断被认为一个主要紧张的事件(mean+/-SD 分数：72+/-25 ) ，显著地爱一个的不到死亡(89+/-13， P【0.0001 ) 并且离婚(78+/-23， P【0.007 ) ，但是多于工作打发(68+/-30， P【0.04 ) 并且家移动(26+/-24， P【0.0001 ) 。CHC 被认为严重疾病(74+/-19 ) ，在爱滋病以后(94+/-08， P【0.001 ) 并且癌症(91+/-11， P【0.001 ) ，但是在糖尿病前(66+/-23， P【0.001 ) 并且高血压(62+/-20， P【0.001 ) 。察觉的 CHC 严厉不与肝疾病的实际严厉有关，根据 Metavir 纤维变性 20 估计了。在里面多变量分析，诊断相关的应力与察觉的疾病严厉(P【0.001 ) 有关，特点焦虑(P【0.001 ) 和通过输血(P【0.001 ) 的感染。结论：我们的结果显示出 CHC 的诊断代表的可观的心理、感情的负担，甚至当重要的肝疾病不在时。当宣布 CHC 的诊断以便减少它的否定效果时，他们应该被考虑。

Investigation of stressful life events in patients with systemic sclerosis

Objective: To assess the occurrence of stressful life events in the year before the initiation of systemic sclerosis. Methods: A consecutive series of 40 patients with systemic sclerosis (mean age (56.3±11.9) years, mean disease duration (4.3±3.1) years; 32 females and 8 males), including 28 with diffuse cutaneous scleroderma and 12 with limited cutaneous scleroderma, were evaluated. A control group of 40 healthy subjects free of systemic sclerosis also was included. Socioeconomic status was inves- tigated and Paykel's interview for recent life events (a semi-structured research interview covering 64 life events) was conducted. Results: Patients with systemic sclerosis showed higher percentages of lower education (72.5%) and working class (82.5%), and reported more stressful life events (P<0.05), such as exits (P<0.05), undesirable events (P<0.01), and uncontrolled events (P<0.001), when compared with the control. More events that had an objective negative impact (P<0.001) were also reported in systemic sclerosis patients than in the control. These results are in accordance with a multifactorial model of pathogenesis in systemic sclerosis. Conclusion: We reported a strong relationship between stressful life events and the initiation of systemic sclerosis. Our findings are consistent with current understanding of the extensive links of behavioral responses to stress with neurophysiological and biochemical processes.

The association between critical life events, sociodemographic data and physical activity in the development of myocardial infarction in smokers and ex-smokers

Background: Psychosocial factors attract interest in investigating the occurrence of cardiovascular disease. Design This study aimed to examine the impact of critical life events on the development of myocardial infarction in smokers and ex-smokers. We hypothesized that critical life events increase the risk of the disease. Methods: Data were taken from the Cologne Smoking Study (CoSmoS), a retrospective multicentre case-control study that examines which psychosocial factors may lead to a higher risk for smokers and ex-smokers of suffering from a myocardial infarction. Our sample consisted of n = 278 myocardial infarction participants and control participants. Both groups had a history of smoking. Logistic regression was used in the analysis. Results: The study results of the smoking and ex-smoking participants showed that sociodemographic data like gender and age have an effect on the development of myocardial infarction. Physical activity seems to offer protection aganist myocardial infarction. Final, the unexpected result that the experience of at least one critical life event seems to have a positive effect on health and so lowers the risk of myocardial infarction. Conclusions: Socio-demographic data and physical activity have an effect on the development of myocardial infarction. Participants with experience of critical life events appear to be strengthened after the events and possess adequate resources to protect their health.

Stressful life events,psychosocial health and general health in preschool children before age 4

Background The impact of stressful life events(SLEs)in early childhood is often ignored.We aimed to examine longitudinal associations between SLEs and psychosocial and general health in preschool children.Methods Twelve SLEs occurring before the age of 24 months were assessed and categorized by frequency(no events,1-2 SLEs,and>2 SLEs)and overall tension(no events,low,and high)(n=1431).Psychosocial and general health were meas-ured three times at the age of 24,36 and 45 months.The associations were examined by logistic regression models using generalized estimating equations to handle repeated measurements.Results Half(48.4%)of the families experienced SLEs,and 23.8%perceived high-tension SLEs before the children were aged 24 months.Gender differences were observed in the association between SLEs and psychosocial health.Compared to girls without SLEs,girls who experienced>2 SLEs[OR=3.31,95%confidence interval(CI)2.05-5.35]or high-tension SLEs(OR=3.01,95%CI 2.07-4.39)had higher odds of psychosocial problems from 24 to 45 months.The odds ratios in boys were 2.10(95%CI 1.36-3.24)and 1.47(95%CI 1.06-2.03),respectively.Moreover,only girls'risk of psychosocial problems increased after experiencing 1-2 SLEs(OR=2.15,95%CI 1.54-3.00)or low-tension SLEs(OR=1.90,95%CI 1.31-2.74).Regarding general health,children who experienced>2 SLEs(OR=1.96,95%CI 1.21-3.18)and high-tension SLEs(OR=1.60,95%CI 1.12-2.28)had higher odds of poor general health from 24 to 45 months.Conclusions The findings emphasized that young children's psychosocial and general health can be impacted by experienc-ing SLEs in early childhood.Attention and adequate support for families experiencing SLEs are needed to minimize the potential negative effect of SLEs on child health,particularly in girls.

Perinatal Stroke and Apparent Life-Threatening Event: A Case Report

To analyze how the multidisciplinary clinical, biohumoral, instrumental approach to ALTE (Apparent Life Threatening Event) episode may discover cardiovascular disease in the newborn. Introduction: In the first year of life ALTEs concern 0.8% of access to Pediatric Emergency Department. The cause of apparent life-threatening events (ALTEs) in infants reflects a differential diagnosis that includes an array of congenital or acquired disorders. Approximately 10% - 25% of ap-parent life-threatening events may remain unexplained following a thorough evaluation. Case re-port: B. E., a 2-month-old child, in wellbeing, shortly before meal, during sleep, was not responsive to repeated stimulations;he was hypotonic and unresponsive. About 15 minutes later, he pre-sented a normal tone and state of consciousness. Evaluating the referred symptoms, diagnostic protocol for ALTE was started;the Angio-MRI brain performed as second line analysis showed a focal gliotic lesion at left striatal area. The cardiological evaluation with echocardiography detected a pervium foramen ovale (PFO), with minimum shunt left-right direction. At least, biohumoral tests revealed protrombin gene heterozygosis mutation. Conclusion: Apparent Life-Threatening Events are first manifestation of stroke in infant. Discussion: This report discloses how the multidisciplinary clinical approach is essential in ALTE. The exact management of ALTE patients is very important in situations like this, when the concomitant disease is rare. In fact, arterial stroke incidence in children > 28 days of life is estimated between 1.2 and 7.9 cases/100,000 child-ren/year. However, in the last 20 years, we observed an increased incidence of stroke, probably related to two main causes: a greater attention for this disease and a major survival of children with pathology that arrange for stroke thanks to a better prevention. In conclusion, it’s a fundamental multidisciplinary approach even in following months after the events.

心理韧性缓冲压力生活事件与青少年学业倦怠之间的非线性关系

压力生活事件对青少年的适应性发展具有潜在危害。本研究聚焦于学业倦怠,进一步探索压力生活事件与学业倦怠不同维度之间的关系,以及心理韧性的潜在缓冲作用。基于对3309名青少年的有效调查数据,本研究发现:(1)压力生活事件与青少年学业倦怠的消极核心维度之间具有非线性关系,随着压力生活事件的累积,学业倦怠水平增加的速度由快变慢,表现为饱和模型;(2)心理韧性可以充当缓冲性保护机制,相较于低心理韧性个体,对高心理韧性个体而言,压力生活事件与学业倦怠之间的非线性关系减弱,随着压力生活事件的累积,心理韧性的缓冲性效应显现出来;心理韧性无法调节压力生活事件与学业效能之间的非线性关系。研究结果支持饱和模型而非门槛模型,也为韧性分析框架下不同类型适应指标的区分提供了证据。

负性生活事件与青少年网络欺凌行为的关系——愤怒反刍的中介作用和网络去抑制的调节作用

为探讨负性生活事件对青少年网络欺凌行为的影响,以及愤怒反刍和网络去抑制在这一影响中的作用,采用青少年生活事件量表、愤怒反刍量表、网络欺凌行为问卷和网络去抑制量表对610名青少年进行问卷调查。结果表明:其一,在控制性别和年龄后,负性生活事件显著地正向预测青少年的网络欺凌行为。其二,愤怒反刍在负性生活事件与网络欺凌行为之间存在显著的中介作用。其三,网络去抑制在愤怒反刍与网络欺凌行为之间起到显著的调节作用;青少年的网络去抑制水平越高,愤怒反刍对网络欺凌行为的正向预测作用越强。这一研究结果对减少网络欺凌行为的干预措施提供了新的视角。

循序渐进的运动康复护理对慢性心衰患者运动耐力、生活质量及不良心脏事件的影响

目的探究循序渐进的运动康复护理对慢性心衰患者运动耐力、生活质量及不良心脏事件的影响。方法选取2022年6月-2023年6月我院收治的106例慢性心衰患者进行研究。以随机数字表法均分为2组。对照组(53例):基础护理。观察组(53例):循序渐进的运动康复护理。比较6 MWD、生活质量、不良心脏事件、满意度。结果干预前,两组6 MWD相比差异不显著(t=0.267,P=0.790),干预3个月后,两组6 MWD均显著提升(t=11.710,P=0.000,t=8.469,P=0.000),且观察组(403.18±62.11)m高于对照组(375.51±68.43)分,差异显著(t=2.180,P=0.032)。干预前,两组生活质量评分相比差异不显著(t=1.690,P=0.094),干预3个月后,两组生活质量评分均显著提升(t=14.053,P=0.000,t=8.409,P=0.000),且观察组(47.11±3.16)分高于对照组(42.34±3.28)分,差异显著(t=7.625,P=0.000)。与对照组16.98%的心衰加重、心源性再入院、急性心肌梗死、心律失常等不良心脏事件总发生率相比,观察组(3.77%)显著降低,差异显著(χ^(2)=4.970,P=0.026)。观察组满意度(90.57%)优于对照组(75.47%),差异显著(χ^(2)=4.283,P=0.039)。结论循序渐进的运动康复护理在提升慢性心衰患者运动耐力方面有积极意义。该护理能够提高患者生活质量及满意度,降低不良心脏事件的发生率。

精神分裂症患者的负性生活事件与复发:社会支持的调节作用

目的探讨精神分裂症患者负性生活事件、复发与社会支持之间的关系,以及社会支持在负性生活事件与复发之间的调节作用。方法采用便利抽样法,抽取宁夏精神卫生中心门诊就诊的215例精神分裂症患者。采用社会再适应评定量表(SRRS)、社会支持评定量表(SSRS)、简明精神病评定量表(BPRS)、临床总体印象-严重程度量表(CGI-S)、Morisky药物依从性量表-8(MMAS-8)分别对负性生活事件、社会支持、复发、疾病严重程度和药物依从性进行测量。采用Spearman相关分析探讨负性生活事件、复发和社会支持之间的相关性,采用二元Logistic回归分析探讨一般资料、负性生活事件、社会支持对复发的影响,采用SPSS PROCESS 3.4探讨社会支持对负性生活事件与复发的调节作用。结果负性生活事件与复发呈正相关(P<0.01),主观社会支持、客观社会支持和社会支持均与复发呈负相关(P均<0.05)。主观社会支持在负性生活事件和复发之间的调节作用显著(P<0.01)。结论负性生活事件和社会支持均与精神分裂症复发密切相关,主观社会支持在负性生活事件和复发之间起到调节作用。

生活事件对大学生抑郁的影响:反刍思维、自我损耗的中介作用和心理韧性的调节作用

目的 探究生活事件和大学生抑郁间的关系,检验反刍思维和自我损耗的中介作用以及心理韧性的调节作用。方法采用流调中心抑郁量表简版、青少年生活事件量表、反刍思维量表、自我损耗量表、青少年心理韧性量表,对526名大学生进行问卷调查。结果 生活事件对大学生抑郁的影响有两条中介路径在发挥作用:反刍思维的独立中介作用及反刍思维和自我损耗的链式中介作用;心理韧性对反刍思维独立中介作用的后期阶段具有显著的调节作用。结论 生活事件并不能直接影响大学生抑郁,而是通过反刍思维和自我损耗的中介作用间接影响和作用;心理韧性可以缓冲反刍思维对大学生抑郁的负面影响。大学生抑郁防治可以从提高心理韧性和降低反刍思维入手。

气候变化事件对头足类繁殖、年龄生长与早期生活史影响的研究进展

头足类是重要的渔业资源之一,其渔业生物学特性极易受到海洋环境变化的影响。气候系统中的能量主要储存载体是海洋。近年来频发的气候变化事件引发海洋环境因子变动,直接或间接地改变了头足类的渔业生物学特性,对头足类的渔业生产造成影响。为此,本文归纳和总结了气候变化对头足类繁殖、年龄生长与早期生活史等3个方面的影响,并提出了展望。结果表明,气候变化事件的发生极易影响头足类动物的渔业生物学特性,海洋环境因子中的温度和初级生产力变动为主要影响因素。目前,相关研究对象多为柔鱼科和枪乌贼科等经济种类,选用的海洋环境因子也多为海洋环境温度,今后应结合其他海洋环境数据研究气候变化事件对其他种类的影响。本文旨为研究气候变化事件对头足类渔业生物学特性的影响提供理论依据,为近年来气候变化事件频发下头足类渔业的可持续发展提供科学指导。

应激生活事件和社会支持对大学生抑郁风险预警阈值研究

目的:抑郁是青少年最常见的情绪问题。其中,近期应激和社会支持是影响大学生抑郁的关键危险性因素和保护性因素,本研究探索这两个关键因素与大学生抑郁关系中可能存在的阈值效应,以期为提升抑郁风险预测的精准性和有效性,以及发展抑郁风险预警系统提供科学依据。方法:整群抽取我国中部H省3所地方普通本科高校2018-2022年入学的14043名本科生进行调查研究。采用SPSS 26.0对数据进行描述性统计分析、相关分析和线性回归分析,并采用R3.5.2进行分段回归模型(PRM)探索应激生活事件和社会支持对大学生抑郁的预测阈值。结果:①应激生活事件、社会支持与抑郁之间存在显著的两两相关,其中,社会支持与应激生活事件、抑郁存在显著的负相关(P<0.01),应激生活事件与抑郁存在显著的正相关(P<0.01);②应激生活事件的阈值达到42.055后,应激生活事件对抑郁水平的诱发作用愈发显著。而社会支持水平的阈值达到18.318后,社会支持对抑郁水平的抑制作用受到削弱;③根据应激生活事件和社会支持对抑郁的阈值效应可将大学生群体分为4组,高应激生活事件低社会支持组和高应激生活事件高社会支持组的大学生抑郁水平显著高于低应激生活事件低社会支持组和低应激生活事件高社会支持组(P<0.05),且高应激生活事件低社会支持组学生的抑郁水平又显著高于高应激生活事件高社会支持组学生(P<0.05);④4个组别的大学生在性别上的分布也存在显著差异(χ^(2)=129.014,P<0.001),高应激生活事件低社会支持组的男生占比(43.7%)明显高于总体样本中男生的比例(30.1%)。结论:应激生活事件、社会支持与大学生抑郁之间存在阈值效应,根据阈值效应分类的高应激生活事件低社会支持组大学生的抑郁水平更为严重;应激生活事件低于42.055阈值水平,社会支持高于18.318的阈值时,大学生的抑郁情绪会得到明显缓解。