Pancreatic cancer is expressed as a disorder of chaos that leads to impairment in biochemical and metabolic physiology of pancreas. It is considered as the most intractable and fatal among all gastrointestinal (GI) ca...Pancreatic cancer is expressed as a disorder of chaos that leads to impairment in biochemical and metabolic physiology of pancreas. It is considered as the most intractable and fatal among all gastrointestinal (GI) cancers. The early occurrence of metastatic spread and the development of intrinsic and acquired resistance during drug treatment limit its prognosis at the right time. The universalized treatment involves surgical resection in which only a minority (in vitro, animal and clinical studies are required for worthy manifestations.展开更多
Natural bioactive compounds from plants are of great importance in modern therapeutics,which are used to prepare antibiotics, growth supplements or some other therapeutics. Ltheanine is such a bioactive amide amino ac...Natural bioactive compounds from plants are of great importance in modern therapeutics,which are used to prepare antibiotics, growth supplements or some other therapeutics. Ltheanine is such a bioactive amide amino acid presented in different plants and fungi,especially in tea. Theanine has influential effects on lifestyle associated diseases, such as diabetes, cardiovascular disorders, hypertension, stress relief, tumor suppression,menstruation and liver injury. This amino acid can maintain normal sleep and improve memory function and nullify effect of the neurotoxins. The rate of bioavailability and its medium of ingestion in the body is one of the great concerns for its additional antioxidant properties. Pharmacokinetics of the bioactive compound and its mode of action are described herewith. The biosynthesis and industrial synthesis are also reviewed to promote accelerated production of this bioactive compound in the pharmaceutical industries.展开更多
文摘Pancreatic cancer is expressed as a disorder of chaos that leads to impairment in biochemical and metabolic physiology of pancreas. It is considered as the most intractable and fatal among all gastrointestinal (GI) cancers. The early occurrence of metastatic spread and the development of intrinsic and acquired resistance during drug treatment limit its prognosis at the right time. The universalized treatment involves surgical resection in which only a minority (in vitro, animal and clinical studies are required for worthy manifestations.
文摘Natural bioactive compounds from plants are of great importance in modern therapeutics,which are used to prepare antibiotics, growth supplements or some other therapeutics. Ltheanine is such a bioactive amide amino acid presented in different plants and fungi,especially in tea. Theanine has influential effects on lifestyle associated diseases, such as diabetes, cardiovascular disorders, hypertension, stress relief, tumor suppression,menstruation and liver injury. This amino acid can maintain normal sleep and improve memory function and nullify effect of the neurotoxins. The rate of bioavailability and its medium of ingestion in the body is one of the great concerns for its additional antioxidant properties. Pharmacokinetics of the bioactive compound and its mode of action are described herewith. The biosynthesis and industrial synthesis are also reviewed to promote accelerated production of this bioactive compound in the pharmaceutical industries.
