Lille, capital of Northern Province in France, is an industrial city.As the tunnel crossing under the English Channel was completed in 1994, Lille has become a place linking London, Paris and Brussels as well as a sit...Lille, capital of Northern Province in France, is an industrial city.As the tunnel crossing under the English Channel was completed in 1994, Lille has become a place linking London, Paris and Brussels as well as a site for European automatic navigation satellite facilities. The journey takes one hour by TGV from Paris Airport to Lille.展开更多
AIM To determine whether infection in patients with acute severe alcoholic hepatitis(AAH) treated with corticosteroids is associated with increased mortality.METHODS Consecutive patients with AAH were treated with ste...AIM To determine whether infection in patients with acute severe alcoholic hepatitis(AAH) treated with corticosteroids is associated with increased mortality.METHODS Consecutive patients with AAH were treated with steroids and recruited to the study. Clinically relevant infections(body temperature > 38 ℃ or < 36 ℃ for more than 4 h, ascitic neutrophil count > 0.25 ×109/L, consolidation on chest radiograph or clinically relevant positive microbiological culture of bodily fluid) were recorded prospectively. Clinical and laboratory parameters were recorded and survival at 90 d and 6 mo was determined. Univariate analysis of factors associated with 90-d mortality was performed and significant variables included in a multivariate analysis.RESULTS Seventy-two patients were included in the final analysis(mean age 47.9 years, 26% female, mean discriminant function 53.0). Overall mortality in the group occurred in 15(21%), 23(32%) and 31(43%) at day 28, day 90 and 1 year respectively. 36(50%) had a clinically relevant infection during their hospitalisation(23 after initiation of steroids). The median time to development of incident infection after commencement of steroids was 10 d. The commonest site of infection was ascites(31%) and bacteraemia(31%) followed by urinary tract(19%) and respiratory tract(8%). Forty-one separate organisms were isolated in 33 patients; the most frequent genus was Escherichia(22%) and Enterococcus(20%). Infection was not associated with 90-d or 1 year mortality but was associated with higher creatinine, model for end-stage liver disease and Lille score. Baseline urea was the only independent predictor of 90-d mortality.CONCLUSION Clinically relevant infections are common in patients with AAH but are not associated with increased 90-d or 1 year mortality.展开更多
Jean-Louis Callens,Secretary General of Federation du Nord of Secours Populaire Francais(SPF),led an eight-member delegation composed of the mayors of Lille,Gravelines and Douchy-les-Mines in the
At the invitation of Secours Populaire Francais (SPF), a Chinese youth delegation composed of members of the Beijing Fengtai Children and Youth Palace and students of No. 1 Middle School of Anyang City of Henan Provin...At the invitation of Secours Populaire Francais (SPF), a Chinese youth delegation composed of members of the Beijing Fengtai Children and Youth Palace and students of No. 1 Middle School of Anyang City of Henan Province, sent by the CPAFFC,paid a visit to France from July 19 to 30, 2012. The aim was to deepen and expand cooperation between the CPAFFC and the SPF and strengthen friendly exchanges between the youth of the two countries and contribute to展开更多
文摘Lille, capital of Northern Province in France, is an industrial city.As the tunnel crossing under the English Channel was completed in 1994, Lille has become a place linking London, Paris and Brussels as well as a site for European automatic navigation satellite facilities. The journey takes one hour by TGV from Paris Airport to Lille.
文摘AIM To determine whether infection in patients with acute severe alcoholic hepatitis(AAH) treated with corticosteroids is associated with increased mortality.METHODS Consecutive patients with AAH were treated with steroids and recruited to the study. Clinically relevant infections(body temperature > 38 ℃ or < 36 ℃ for more than 4 h, ascitic neutrophil count > 0.25 ×109/L, consolidation on chest radiograph or clinically relevant positive microbiological culture of bodily fluid) were recorded prospectively. Clinical and laboratory parameters were recorded and survival at 90 d and 6 mo was determined. Univariate analysis of factors associated with 90-d mortality was performed and significant variables included in a multivariate analysis.RESULTS Seventy-two patients were included in the final analysis(mean age 47.9 years, 26% female, mean discriminant function 53.0). Overall mortality in the group occurred in 15(21%), 23(32%) and 31(43%) at day 28, day 90 and 1 year respectively. 36(50%) had a clinically relevant infection during their hospitalisation(23 after initiation of steroids). The median time to development of incident infection after commencement of steroids was 10 d. The commonest site of infection was ascites(31%) and bacteraemia(31%) followed by urinary tract(19%) and respiratory tract(8%). Forty-one separate organisms were isolated in 33 patients; the most frequent genus was Escherichia(22%) and Enterococcus(20%). Infection was not associated with 90-d or 1 year mortality but was associated with higher creatinine, model for end-stage liver disease and Lille score. Baseline urea was the only independent predictor of 90-d mortality.CONCLUSION Clinically relevant infections are common in patients with AAH but are not associated with increased 90-d or 1 year mortality.
文摘Jean-Louis Callens,Secretary General of Federation du Nord of Secours Populaire Francais(SPF),led an eight-member delegation composed of the mayors of Lille,Gravelines and Douchy-les-Mines in the
文摘At the invitation of Secours Populaire Francais (SPF), a Chinese youth delegation composed of members of the Beijing Fengtai Children and Youth Palace and students of No. 1 Middle School of Anyang City of Henan Province, sent by the CPAFFC,paid a visit to France from July 19 to 30, 2012. The aim was to deepen and expand cooperation between the CPAFFC and the SPF and strengthen friendly exchanges between the youth of the two countries and contribute to
