Internal limiting membrane peeling combined with silicone oil or air tamponade for highly myopic foveoschisis

AIM:To compare the efficacy of pars plana vitrectomy(PPV)combined with internal limiting membrane(ILM)and silicone oil or sterile air tamponade for the treatment of myopic foveoschisis(MF)in highly myopic eyes.METHODS:This retrospective study included 48 myopic eyes of 40 patients with MF and axial lengths(ALs)ranging from 26-32 mm treated between January 2020 and January 2022.All patients were underwent PPV combined with ILM peeling followed by sterile air or silicone oil tamponade and followed up at least 12mo.Based on the features on spectral-domain optical coherence tomography(SD-OCT),the eyes were divided into the MF-only group(Group A,n=15 eyes),MF with central foveal detachment group(Group B,n=20 eyes),and MF with lamellar macular hole group(Group C,n=13 eyes).According to AL,eyes were further divided into three groups:Group D(26.01-28.00 mm,n=12 eyes),Group E(28.01-30.00 mm,n=26 eyes),and Group F(30.01-32.00 mm,n=10 eyes).The best-corrected visual acuity(BCVA),central foveal thickness(CFT),and complications were recorded.RESULTS:The patients included 16 males and 24 females with the mean age of 56±9.82y.The BCVA and CFT improved in all groups after surgery(P<0.01),while there was no significant difference of the CFT in Group A,B,and C postoperatively(P>0.05).The intergroup differences of BCVA and CFT postoperatively were statistically significant in Group D,E,and F.Twenty eyes were injected with sterile air,and 28 eyes were injected with silicone oil for tamponade based on the AL.However,there was no statistically significant difference among Groups D,E,and F in terms of the results of sterile air or silicone oil tamponade.The mean recovery time was 5.9mo for MF patients subjected to silicone oil tamponade and 7.7mo for patients subjected to sterile air tamponade,and the difference was not statistically significant.CONCLUSION:PPV and ILM peeling combined with silicone oil or sterile air tamponade can achieve good results for MF in highly myopic eyes with ALs≤32 mm.

Travel-Limiting Disabilities in the United States: Why Accessibility Matters?

This study evaluates the distribution of travel-limiting disabilities across genders and geographic locations in the United States. This study aims to describe and compare the socioeconomic and demographic variables of the people with and without travel-limiting disabilities across geographic locations and gender. The study further evaluates the trip purpose and impact of Covid-19 fourth wave pandemic on the use of public transit and travel to physical workplace for the people with and without travel-limiting disabilities across gender and geographic locations. The study uses the 2022 weighted National Household Travel Survey dataset and employs descriptive statistics. Results reaffirm the findings from previous literature that there are more people with travel-limiting disabilities in urban areas and among women. Over 50 percent of people aged 65 and above have a form of travel-limiting disabilities. The most trip for people with travel-limiting disabilities is made for shopping and medical purposes. Across all categories, rural areas, urban areas, male and female for the people without travel-limiting disabilities, COVID-19 fourth wave did not change the pattern of trips made to physical workplace as pre-COVID-19 era. This pattern is also observable for the people with travel-limiting disabilities in rural and urban areas. Females with travel-limiting disabilities reported making less trips to physical workplaces while male reported doing the same as before COVID-19 era. The study concludes that the quantification of travel-limiting disabilities across geographic location and gender is vital in disability study and could drive policy implementation for improved accessibility for the vulnerable population.

Limiting Magnitudes of the Wide Field Survey Telescope(WFST)

Expected to be of the highest survey power telescope in the northern hemisphere,the Wide Field Survey Telescope(WFST)will begin its routine observations of the northern sky since 2023.WFST will produce a lot of scientific data to support the researches of time-domain astronomy,asteroids and the solar system,galaxy formation and cosmology and so on.We estimated that the 5σlimiting magnitudes of WFST with 30 s exposure are u=22.31mag,g=23.42 mag,r=22.95 mag,i=22.43 mag,z=21.50 mag,w=23.61 mag.The above values are calculated for the conditions of airmass=1.2,seeing=075,precipitable water vapor=2.5 mm and Moon-object separation=45°at the darkest New Moon night of the Lenghu site(V=22.30 mag,Moon phaseθ=0°).The limiting magnitudes in different Moon phase conditions are also calculated.The calculations are based on the empirical transmittance data of WFST optics,the vendor provided CCD quantum efficiency,the atmospherical model transmittance and spectrum of the site.In the absence of measurement data such as sky transmittance and spectrum,we use model data.

How internal limiting membrane peeling revolutionized macular surgery in the last three decades

INTRODUCTION The Italian anatomist Filippo Pacini discovered the internal limiting membrane(ILM) in 1844[1]. The ILM is the basement membrane of the retinal Müller cells representing the structural interface between the retina and the vitreous. The macular ILM is thickest, measuring 2.5 μm and progressively thins to 0.5 μm at the vitreous base[2].

Laser shaping and optical power limiting of pulsed Laguerre–Gaussian laser beams of high-order radial modes in fullerene C60

We study the strong nonlinear optical dynamics of nanosecond pulsed Laguerre–Gaussian laser beams of high-order radial modes with zero orbital angular momentum propagating in the fullerene C60molecular medium. It is found that the spatiotemporal profile of the incident pulsed Laguerre–Gaussian laser beam is strongly reshaped during its propagation in the C60molecular medium. The centrosymmetric temporal profile of the incident pulse gradually evolves into a noncentrosymmetric meniscus shape, and the on-axis pulse duration is clearly depressed. Furthermore, the field intensity is distinctly attenuated due to the field-intensity-dependent reverse saturable absorption, and clear optical power limiting behavior is observed for different orders of the input pulsed Laguerre–Gaussian laser beams before the takeover of the saturation effect;the lower the order of the Laguerre–Gaussian beam, the lower the energy transmittance.

Perspective: Limiting Antimicrobial Resistance with Artificial Intelligence/Machine Learning

The author traces his experience with the application of computers in clinical microbiology over the past 60 years,specifically in directing clinicians to treat bacterial infections diagnosed by the laboratory and the antibacterial agent(s)that could be used to treat those infections.Appropriate use of antibiotics will result in reduced antimicrobial resistance,which is increasing worldwide.An early form of AI,Mycin(1976),a system based on rules provided by experts designed to propose antibiotic regimens for central nervous system infections,was never applied due to the limitations in the number of rules that could be incorporated into the clinical workflow.Machine learning(ML)was developed to overcome the limitations of expert systems.Several variables that influence the outcome bacteria/drug interaction,such as the source of the infection,absence of antimicrobial resistance markers,patients’health profile,and the historical susceptibility within the hospital and the local area are incorporated in the proposed comprehensive AI/ML program.The role of AI in the discovery of new antimicrobial agents is also addressed.

Limiting Factors and Countermeasures for the Development of Biological Herbicides

This paper mainly analyzes the main limiting factors in the development of biological herbicides,such as narrow herbicidal spectrum,vulnerable to environmental impacts,difficulties in preparing dosage forms,difficult separation and low yield of active substances,biological safety,etc.Moreover,countermeasures and suggestions are put forward,including strengthening the study of biological screening of herbicidal activity,microbial metabolites and their use as lead compounds,dosage forms,fungi complex formulation,fungi and herbicide complex formulation,and fermentation technology.

Study on Hydrogen Storage Properties,Anti-Oxide Ability and Rate Limiting Step of ZrCr-Based Alloy after Introducing Cobalt as Additive

In this work,the microstructure,hydrogen storage properties,anti-oxide ability and rate limiting step of Zr(Cr_(1−x)Co_(x))_(2)(x=0,0.2,0.4 and 0.6)alloys have been investigated.After studying the crystal structure,we found that all alloy samples could show C14-type phase but the alloy sample x=0 could also show a small amount of Cr phase.Rietveld fitting showed that lattice parameter and unit cell volume of C14-type phase decreased with increasing x.After further research,it was clear that the first hydrogen absorption capacity decreased with increasing x.But introducing more Co content had a positive influence on the effective hydrogen storage capacity and cyclic hydrogen absorption and desorption properties of the alloy sample.We also found that adding Co to ZrCr_(2)alloy could improve its anti-oxide ability.In addition to this,the rate limiting step model was also studied.

家蚕素斑品种菁松的茶斑限性定向转育

为在家蚕现行素斑品种菁松的幼虫发育早期进行雌雄性别鉴别,实现雌雄分养分缫差异化利用目的,用普斑限性品系云蚕7A的雌与茶斑品系Cb的雄杂交后,再分别与现行素斑品系菁松A、菁松B杂交,其后代连续数次回交素斑亲本后自交,结合分类选择进行个体和蛾区选择淘汰,将云蚕7A的普斑限性基因和Cb的茶斑基因转入现行素斑品种菁松中,定向转育得到菁A茶限和菁B茶限。结果表明:转育过程中,幼虫斑纹分化成颜色与形状易于分辨的茶斑与非茶斑2种类型,转育得到的菁A茶限和菁B茶限幼虫在3龄初期就会呈现茶斑颜色深浅明显不同的分化,能准确分辨雌雄,其虫蛹率分别为96.91%和96.40%,全茧量分别为1.62 g和1.56 g,茧层率分别为23.78%和23.26%,经济性状与其轮回亲本的差异较小,表现出健康好养、茧质优良等特性。研究结果可为创建特殊性状的育种材料、差异化利用雌雄蚕,以及降低雄蚕种繁育成本奠定基础。

平台经济领域强化反垄断的正当性与合理限度

近些年来,国内外在平台经济领域开展了声势浩大的反垄断行动,尤其是欧盟出台的《数字市场法》和我国强调“强化反垄断和防止资本无序扩张”备受关注。基于平台经济竞争的鲜明特点和数字平台对经济社会的巨大影响,强化平台经济领域的反垄断有其理论上的正当性和现实的必要性。与此同时,平台经济创新发展的内在要求又决定了在平台经济领域的反垄断有其合理的边界和必要的限度。美国和欧盟等在平台经济领域反垄断上的差异性反映了国际竞争的现实情况,我国需要从国家利益最大化角度出发对平台经济领域反垄断策略做出理性选择,以促进我国平台经济规范健康持续发展。

基于光储混合配置的级联H桥型光伏逆变器功率平衡策略

级联H桥(cascade H-bridge,CHB)变换器由于其模块化结构,已成为大规模光伏(photovoltaic,PV)并网逆变器的优选方案。然而,在不同光照强度和温度下,不同区域PV组件之间发电功率不同,导致CHB变换器相间输出功率不均衡、不稳定等问题。为此,文中提出一种基于CHB结构的光储混合电能路由,在三相CHB光伏逆变器中配置少量的储能模块,利用光储协同控制,维持CHB内部功率稳定,消除分布式PV在相间产生的不均衡功率,且变换器输出功率能够时刻满足网侧上层功率调度,提高了光伏电站的稳定性。针对系统安全区域,在载波移相调制策略下,全桥子模块传输的功率受到约束,并对光伏和储能模块的配置作详细分析。最后,通过仿真以及实验验证所提拓扑及控制策略的正确性和有效性。

大学生就业能力培养中高校的“有限责任”

培养大学生就业能力是高等教育的本职所在、应有之义,是高校的主责主业之一,但就业能力培养参与主体多元、影响因素众多,不能任意放大单一主体的责任,亟须在高校、政府、雇主、学生个体等利益相关者之间建立明确的责任分担机制。高校在大学生就业能力培养方面客观存在权力有限性、能力有限性与资源有限性,应针对性进行责任的纵向和横向配置,建立基于时间和基于范畴的有限责任,明确大学生就业能力培养中高校的责任边界,有效区分高校在大学生就业能力培养内容产品提供方面的主导责任、个人与自我方面的引导责任以及服务与机会方面的支持责任。

石灰石露天矿高陡边坡稳定性计算分析

以西南某石灰石矿高陡边坡为研究对象,根据矿山边坡现状、边坡岩体结构和结构面发育特征因素对“现状边坡”和“终了边坡”进行地质分区,通过岩石室内物理力学试验获得坡体岩石物理力学参数,采用GSI法计算边坡岩体内摩擦角、粘聚力、变形模量和泊松比等参数,评估边坡地质强度特性,采用Morgenstern-Price极限平衡法分三种荷载工况分别计算“现状边坡”和“终了边坡”各分区稳定性系数。经分析,该石灰石矿各地质分区“现状边坡”和“终了边坡”稳定性好,采场边坡参数设计合理,可为矿山扩产安全设施设计和安全生产提供参考。

并网逆变器非线性特性建模及稳定性研究综述

并网逆变器作为连接新能源分布式发电和电网之间的关键接口,发挥着将电能高效、高质量馈入电网的重要作用。随着新能源渗透率的持续提高,并网点处电网存在诸如高电网阻抗、丰富的低频谐波、电压幅值/频率波动甚至故障等复杂状况。鉴于并网逆变器本质上是一个多输入、强耦合的非线性系统,沿用传统的线性建模与分析方法已难以解释工程中的复杂谐波振荡现象,并网逆变器的稳定性分析及其稳定运行受到巨大挑战。为此,该文首先具体阐述了线性与非线性和系统受扰大小之间的关系,指出大干扰稳定性分析更依赖于非线性建模及分析方法的应用。在此基础上,对已见诸报道的并网逆变器稳定性分析方法进行了归纳和对比。然后,详细阐述了稳定性分析方法在并网逆变器特定非线性环节中的应用。最后,总结并讨论了现有研究的不足,以期进一步促进“双高”背景下并网装置非线性建模和稳定性分析的研究。

大截面矩形顶管施工对既有管线影响研究

顶管施工会扰动邻近建筑物,危及工程安全。该文以苏州市城北路综合管廊元和塘段顶管工程为背景,通过ABAQUS有限元分析软件建立三维模型,研究顶管下穿地下管线施工对管周土及既有管线影响,并基于极限分析方法探讨了管线失稳模式。结果表明:大直径矩形顶管顶进方向的影响范围约为2倍顶管宽度,两侧的影响范围约为1倍顶管宽度,地下管线到顶管轴线的水平距离为0.5倍~1倍顶管宽度时,应注意管线受到的水平方向附加荷载是否会导致管线破坏;管线与顶管相对位置对管线破坏影响较为显著,越靠近顶管的管线破坏越严重,滑移线由顶管两侧经由管线向地面发展,破坏部位由管线顶部两侧延伸至底部;除受与顶管相对位置影响外,管线破坏模式还受矩形顶管形状影响,管线顶部及靠近顶管顶角区域破坏风险最大。

土性对工程泥浆固化强度影响规律及微观机理

本文开展了一系列不同液限高分子吸水树脂固化工程泥浆无侧限抗压强度试验,探讨了泥浆土液限对固化效率的影响规律,对比研究了掺入高岭土对泥浆固化强度的改进程度,最后基于XRD和SEM试验揭示了液限和高岭土对固化泥浆强度影响的微观机理。结果表明:随着泥浆土液限的增大,固化泥浆土强度逐渐降低,固化效率随着泥浆土液限增大显著衰减,当液限增加10%,固化泥浆土强度qu平均减少48.2%。然而高岭土的掺入则显著提升了固化泥浆土的强度,并且强度增长率随着龄期逐渐增大,对于龄期为90天时,增加40%高岭土能够提升固化泥浆土强度qu 1.17倍。微观结构试验表明泥浆土液限变化对水化产物产量的影响较小,固化泥浆土强度随泥浆土液限减小主要是由于固化泥浆土孔隙随着泥浆土液限增大而增多,使得微观结构松散从而导致强度降低。高岭土的掺入则显著提升了固化泥浆土的水化产物产量,增强了固化泥浆土胶结强度,从而提升了固化泥浆土强度。因此,在实际工程中,一方面可以通过调配泥浆土液限来提高固化效率;另一方面可以通过掺入高岭土或者一些高岭土基废弃物(如高岭土尾矿)来提高固化强度,实现“以废制废”绿色环保的理念。

有限责任公司“人”的特征重构--基于人合性的反思

人合性是被我国公司法理论和实务界广泛认可的有限责任公司特征。“人合性”三字虽未明确入法,但是我国《公司法》在1993年制定之初即创设了相关制度,三十年来对人合性的肯定立场没有根本改变,2023年新《公司法》赓续传统,未有突破。在有限公司股东资格认定、股权转让等司法实务中,人合性已经成为司法审判的依据,影响深远。观诸英美法系和大陆法系国家,并无将有限公司列为人合性公司的立法例,而我国公司法上对人合性制度的立法论和解释论皆付诸阙如。实则,有限公司并无先验的所谓人合性特征,其应为契约性和法人实体的二合一。将来《公司法》再修订,应彻底废除有限公司人合性及其制度。

东洞庭湖洪水前后典型湿地植物化学计量特征动态变化

洪水对湿地土壤-植被系统养分循环有重要影响。本研究以东洞庭湖湿地典型植物短尖苔草(Carex brevicuspis)和南荻(Triarrhena lutarioriparia)为研究对象,于2018年洪水期前后(5月、10月)测定短尖苔草和南荻生长特征、生态化学计量特征及土壤理化性质,并对化学计量学特征与环境特征的相关性进行了分析。结果表明:南荻植株的生物量和密度洪水前显著高于洪水后,短尖苔草生物量和密度洪水前后都没有显著差异;短尖苔草、南荻叶片有机碳(SOC)洪水后显著高于洪水前;短尖苔草叶片全氮(TN)洪水前显著低于洪水后;南荻叶片TN、全磷(TP)洪水前显著高于洪水后;短尖苔草叶片TP洪水前后没有显著差异。短尖苔草叶片C∶N、C∶P、N∶P洪水前后均无显著差异,南荻叶片C∶N、C∶P洪水前显著低于洪水后,但N∶P洪水前后无显著差异。东洞庭湖短尖苔草、南荻叶片N∶P<14,东洞庭湖短尖苔草、南荻生长更多的受N限制,洪水前后都与土壤N、P含量无显著相关性。本研究结果对阐明洪水对湿地植物化学计量特征的影响有重要意义。

实验室危险化学品储存限量法规标准研究

随着高校教学科研的不断发展和扩大,开展实验所涉及的危险化学品种类和数量逐年增多,本文针对高校实验室危险化学品存量的现状及存在的问题,选取我国具有代表性的法律、法规和标准,并针对其中关于危险化学品储存及其限量的相关规定进行比较分析,提出符合高校实验室的危险化学品储存限量标准化精细研究的建议,为实验室危险化学品储存管理提供合理合法的依据,有助于提高了危险化学品科学监管水平,降低实验室安全风险。

企业数据的知识产权保护

企业数据和知识产权的客体之间存有共性。二者的保护基础理论相互融通,并且企业数据权利与知识产权权利结构相近似,这为企业数据的知识产权保护奠定了基础。检视现有知识产权制度框架下保护模式的有限性以识别现有制度与企业数据保护问题之间真正无法重合的地带。构建和完善企业数据保护规则须对企业数据进行类型化结构,基于类型化区分和场景化差异探寻不同保护路径。从解释论角度而言,对于无法纳入既有法定权利范畴的企业数据权益,适用《反不正当竞争法》一般条款规制未被类型化权益,关键在于客观审查数据使用行为是否违反商业道德。从立法论角度而言,可参照知识产权的行为规制赋权化路径,将规制焦点建立在对企业数据的利用行为上,对利用行为进行类型化提炼,建构一种以禁止权和报酬权为核心的不完满的控制权和有限度的排他权。