Background and object:The burden of neurological disorders in India is expected to increase due to the rapid demographic and epidemiological transition,with irrational drug use,which is also a global concern.Thus,drug...Background and object:The burden of neurological disorders in India is expected to increase due to the rapid demographic and epidemiological transition,with irrational drug use,which is also a global concern.Thus,drug utilization evaluation is designed to ensure appropriate medicine use within the healthcare settings.The aim of the study was to assess the rate and pattern of drug utilization in the management of neurological disorders.Materials and methods:A hospital-based cross-sectional drug utilization evaluation study on neurological drugs was carried out at the Department of Neurology over a span of six months.All legible prescriptions consisting neurological medications irrespective of patient's gender,aged≥18 years were included for the study.The World Health Organization(WHO)core drug use indicators were used to assess the drug prescribing and utilization patterns.Results:A total of 310 prescriptions were reviewed,where male predominance was found to be 56.45%.Out of 310 prescriptions,drugs belonging to 26 neurological classes were prescribed for the management of various neurological disorders.The majority of patients were diagnosed with epilepsy and the most prescribed drugs per patient were phenytoin(14.8%)and valproic acid(6.45%).By following the WHO core drug prescribing indicators,65.47%of drugs prescribed from the India National List of Essential Medicines,2022,followed by 29.83%of drugs prescribed in generic name and 10.86%of prescriptions including injections.Conclusion:The study findings showed that the prescribing pattern in the Department of Neurology was in accordance with the WHO core prescribing indicators.But,the extent of polypharmacy prescriptions was very high.Therefore,interventions are very necessary to promote rational drug prescribing patterns and thus clinical pharmacists can contribute to assess and review the drug utilization pattern to optimize the drug therapy and improvement in patient safety.展开更多
Aims&Scope Asian Pacific Journal of Tropical Medicine(APJTM),aims to set up and provide an academic communicating platform for international physicians,medical scientists,allied health scientists and public health...Aims&Scope Asian Pacific Journal of Tropical Medicine(APJTM),aims to set up and provide an academic communicating platform for international physicians,medical scientists,allied health scientists and public health workers,especially those of the AsiaPacific region and worldwide on tropical medicine,infectious展开更多
Biological vulnerability translates into behavioral risks that often extend beyond the infancy period. Pre-term children born low birth weight are at risk for behavioral and emotional difficulties, however, little is ...Biological vulnerability translates into behavioral risks that often extend beyond the infancy period. Pre-term children born low birth weight are at risk for behavioral and emotional difficulties, however, little is known about how these difficulties manifest and interact with biological risk and environmental factors. This study examined the extent to which children’s language and dyadic relationship factors facilitate affect regulation and behavior problems in low birth weight children (LBW). Sixty-eight preschool-age children and their mothers participated in the study. Children were administered an assessment of cognitive functioning in which verbal ability was examined, and engaged in a laboratory frustration task designed to elicit negative affect to assess emotion regulation. Results revealed correlations among verbal ability, behavior problems, behavioral synchrony, and emotion regulation. Group differences were found in verbal ability and positive affect in which LBW children demonstrated lower verbal ability scores and less positive affect than full-term children. For the full sample, behavior synchrony moderated the relationship between verbal ability and negative emotion regulation. The results provide evidence of the importance of the functional role of language and dyadic relations in the development of affect regulation and behavior problems. The results also elucidate the importance of integrating social emotional information in developing interventions for pre-term children.展开更多
文摘Background and object:The burden of neurological disorders in India is expected to increase due to the rapid demographic and epidemiological transition,with irrational drug use,which is also a global concern.Thus,drug utilization evaluation is designed to ensure appropriate medicine use within the healthcare settings.The aim of the study was to assess the rate and pattern of drug utilization in the management of neurological disorders.Materials and methods:A hospital-based cross-sectional drug utilization evaluation study on neurological drugs was carried out at the Department of Neurology over a span of six months.All legible prescriptions consisting neurological medications irrespective of patient's gender,aged≥18 years were included for the study.The World Health Organization(WHO)core drug use indicators were used to assess the drug prescribing and utilization patterns.Results:A total of 310 prescriptions were reviewed,where male predominance was found to be 56.45%.Out of 310 prescriptions,drugs belonging to 26 neurological classes were prescribed for the management of various neurological disorders.The majority of patients were diagnosed with epilepsy and the most prescribed drugs per patient were phenytoin(14.8%)and valproic acid(6.45%).By following the WHO core drug prescribing indicators,65.47%of drugs prescribed from the India National List of Essential Medicines,2022,followed by 29.83%of drugs prescribed in generic name and 10.86%of prescriptions including injections.Conclusion:The study findings showed that the prescribing pattern in the Department of Neurology was in accordance with the WHO core prescribing indicators.But,the extent of polypharmacy prescriptions was very high.Therefore,interventions are very necessary to promote rational drug prescribing patterns and thus clinical pharmacists can contribute to assess and review the drug utilization pattern to optimize the drug therapy and improvement in patient safety.
文摘Aims&Scope Asian Pacific Journal of Tropical Medicine(APJTM),aims to set up and provide an academic communicating platform for international physicians,medical scientists,allied health scientists and public health workers,especially those of the AsiaPacific region and worldwide on tropical medicine,infectious
文摘Biological vulnerability translates into behavioral risks that often extend beyond the infancy period. Pre-term children born low birth weight are at risk for behavioral and emotional difficulties, however, little is known about how these difficulties manifest and interact with biological risk and environmental factors. This study examined the extent to which children’s language and dyadic relationship factors facilitate affect regulation and behavior problems in low birth weight children (LBW). Sixty-eight preschool-age children and their mothers participated in the study. Children were administered an assessment of cognitive functioning in which verbal ability was examined, and engaged in a laboratory frustration task designed to elicit negative affect to assess emotion regulation. Results revealed correlations among verbal ability, behavior problems, behavioral synchrony, and emotion regulation. Group differences were found in verbal ability and positive affect in which LBW children demonstrated lower verbal ability scores and less positive affect than full-term children. For the full sample, behavior synchrony moderated the relationship between verbal ability and negative emotion regulation. The results provide evidence of the importance of the functional role of language and dyadic relations in the development of affect regulation and behavior problems. The results also elucidate the importance of integrating social emotional information in developing interventions for pre-term children.
