Research progress of local characteristic drugs for treatment of rheumatoid arthritis in Xinjiang

Rheumatoid arthritis(RA)is a systemic autoimmune disease characterized by synovitis.This disease tends to recur,persist,and is difficult to cure.The pathogenesis of RA is complex.Currently,the commonly used treatments for RA—non-steroidal anti-inflammatory drugs(NSAIDs),disease-modifying anti-rheumatic drugs(DMARDs),glucocorticoids,and immunosuppressants—have notable side effects with long-term use and may be ineffective for some patients.Therefore,it is crucial to find drugs with limited side effects and significant curative effects.Xinjiang's local characteristic drugs have a long history,abundant resources,and are known for their safety and effectiveness in treating RA.In recent years,many studies have reported on the mechanisms of action and therapeutic effects of Xinjiang's local characteristic drugs on RA.This article reviews the pathogenesis of RA,as well as the research progress and treatment characteristics of Xinjiang-featured drugs.

Spatiotemporal Evolution Characteristics of Urban Land Surface Temperature Based on Local Climate Zones in Xi’an Metropolitan,China

Local climate zones(LCZs)are an effective nexus linking internal urban structures to the local climate and have been widely used to study urban thermal environment.However,few studies considered how much the temperature changed due to LCZs transformation and their synergy.This paper quantified the change of urban land surface temperature(LST)in LCZs transformation process by combining the land use transfer matrix with zonal statistics method during 2000–2019 in the Xi’an metropolitan.The results show that,firstly,both LCZs and LST had significant spatiotemporal variations and synchrony.The period when the most LCZs were converted was also the LST rose the fastest,and the spatial growth of the LST coincided with the spatial expansion of the built type LCZs.Secondly,the LST difference between land cover type LCZs and built type LCZs gradually widened.And LST rose more in both built type LCZs transferred in and out.Finally,the Xi’an-Xianyang profile showed that the maximum temperature difference between the peaks and valleys of the LST increased by 4.39℃,indicating that localized high temperature phenomena and fluctuations in the urban thermal environment became more pronounced from 2000 to 2019.

Construction controlling and strength increasing characteristics of locally developed epoxy asphalt mixture

The construction controlling elements,including construction performance at low ambient temperatures,reserved time ranges,and the strength increasing rule,for locally developed epoxy asphalt mixture（LDEAM） are studied through laboratory tests.Air void and Marshall stability are chosen as the performance measures for evaluating the construction quality.The wheel rolling test is used to simulate the actual construction situations,while the Marshall test and the Brookfield viscosity test are adopted to study the strength increasing rule.The experimental results reveal that the LDEAM can be constructed under a low ambient temperature condition of 10℃,and its longest reserved time is 70 min at a reserved temperature of 120℃.Test also shows that the strength of the LDEAM increases with time and temperature before cured.Finally,the theoretical reason for the strength increasing rule is analyzed on the basis of the organic chemistry theory.

Experimental study of power consumption, local characteristics distributions and homogenization energy in gas–liquid stirred tank reactors

In this paper, the power consumption, the vertical local void fraction and the local gas–liquid interfacial area are investigated in the aerated stirred tank reactors(STRs) equipped with a rigid-flexible impeller. Meanwhile, the regressive correlation based on power consumption and interfacial area is proposed. Then a novel homogenization energy(HE = RSDPtm) expression based on power consumption and local interfacial area is redefined and used to indicate the mixing efficiency. The optimal operating mode is selected based on the change of the HE value. This paper can provide research ideas for structural optimization of stirred reactors.

LOCAL ERROR ESTIMATES FOR METHODS OF CHARACTERISTICS INCORPORATING STREAMLINE DIFFUSION

Allen and Liu (1995) introduced a new method for a time-dependent convection dominated diffusion problem, which combines the modified method of characteristics and method of streamline diffusion. But they ignored the fact that the accuracy of time discretization decays at half an order when the characteristic line goes out of the domain. In present paper, the author shows that, as a remedy, a simple lumped scheme yields a full accuracy approximation. Forthermore, some local error bounds independent of the small viscosity axe derived for this scheme outside the boundary layers.

On the Global Significance of XI Jinping＇s Thought on Socialism with Chinese Characteristics for a New Era

XI Jinping＇s thought on socialism with Chinese characteristics for a new era contains Chinesewisdom for the development of socialism in the world,Chinese experience of realizing modernization in adeveloping country,and Chinese solution to the global governing. It clarifies the theoretical puzzlement of ＂theend of history＂,＂the clash of civilizations＂and ＂Western centrism＂,so that it plays an important role inhuman intellectual history. Therefore,one should adopt an international vision and a global perspective tounderstand and evaluate the theoretical significance and practical value of XI Jinpings thought on socialismwith Chinese characteristics for a new era.

Ethnobotanical Knowledge of Local Cassava Varieties and Characteristics Desired by Farmers in Sierra Leone

It has been observed that farmers adopt only a small number of the “improved” cultivars. A nationwide germplasm collection exercise in February 2018 provided the opportunity to collect indigenous technical knowledge (ITK) of the diversity of cassava varieties in terms of: their morphology, growth characteristics, uses (of tubers and leaves) and desirable characteristics. The objective is to see to what extent the objectives of the plant breeders are consistent with what farmers’ value. We performed 405 structured and semi-structured interviews with informants who were selected based on “purposive household sampling”. We found a considerable turn-over in cassava varieties, just over a third (45) have been in cultivation for at least 40 years, however, since the end of the civil war an additional 25 varieties are cultivated, while others varieties seem to have disappeared. One major issue with estimating turnover of varieties is whether the same variety might have several local names, and conversely the same name may be applied to different cultivars. Farmers overwhelmingly use ITK to select and preserve cassava germplasm for future use. Farmers have a clear preference for: sweet taste, high yield, early maturity and easy cooking and preferentially adopt cultivars that have those qualities. Cassava is primarily a human food eaten boiled or fried, some are processed into fufu and gari, and uses as livestock feed and medicine are reported but at low levels. The information produced during this study could help plant breeders choose selection criteria that will ensure their efforts are adopted and sustainable, the importance of preserving the genetic resources of local cultivars is also highlighted.

How Xi Jinping Thought on Diplomacy Guides Major-Country Diplomacy with Chinese Characteristics

Introduced to a greatly changing world,Xi Jinping thought on diplomacy is a strategic planning and top-level design for major-country diplomacy with Chinese characteristics and has a leading role in Chinese diplomacy.Building a new type of international relations and a community with a shared future is at the heart of Chinese foreign policy.Under Xi Jinping’s diplomatic thought,China has shifted focus from a peaceful rise and harmonious world to seeking the core values of globalization.Xi Jinping’s diplomatic thought guides major-country diplomacy with Chinese characteristics in philosophy,principles and practice.

Analysis on Characteristics of Architectural Environment of Traditional Villages in Southwest Mountainous Area:Taking Heijing Ancient Town of Chuxiong as an Example

The formation of the ancient town of Heijing conforms to the natural conditions and local conditions,and makes effective use of the natural mountains,water bodies,trees and other resources of the ancient town,so that the ancient town and nature rely on each other and unify harmoniously.Through the analysis of the environmental characteristics of the ancient town,this paper further explores its cultural connotation.

Types, Distribution Characteristics, and Development Strategies of Rural Characteristic Industry in Xi’an Metropolitan Area

China’s urbanization development has entered the“second half”,which is at a critical stage of transition from the middle stages to the mature stage.The metropolitan area formed by the mega-city radiating the development of surrounding cities and counties is an important spatial carrier of urbanization.The rural characteristic industry is the main path to promote regional economic development and urban-rural integration in the metropolitan area.Exploring the development characteristics of rural characteristic industries in the metropolitan area has important theoretical and practical significance for promoting the effective connection between urban-rural integration and rural revitalization of the metropolitan area and improving the development quality of the metropolitan area.Take the Xi’an metropolitan area as an example and adopt kernel density analysis and other methods to reveal the spatial differentiation rules of rural characteristic industries.On this basis,the three-dimensional development strategy of“industry-spatial-institutional”for the development of the rural characteristic industry is proposed,to provide theoretical reference for the development of rural characteristic industry in metropolitan areas.

XI JINPING THOUGHT ON SOCIALISM WITH CHINESE CHARACTERISTICS FOR A NEW ERA OPENS NEW HORIZON FOR INTERNATIONAL COMMUNIST MOVEMENT

The 19th National Congress of the Communist Party of China （CPC） established Xi Jinping Thought on Socialism with Chinese Characteristics for a New Era as the guiding ideol- ogy of the CPC, marking a new leap forward in synthesizing basic principles of Marxism with China＇s concrete conditions. This Thought enriches and develops scientific socialism, the guiding ideology of the International Communist Movement. With brave new intellectual horizon, it deepens the understanding of the laws governing government by communist parties, construction of socialism and development of human society, occupying an important place of historical significance in the history of development of Marxism and the International Communist Movement. Guided by Xi Jinping Thought on Socialism with Chinese Characteristics for a New Era, socialism with Chinese characteristics has made great historical achievements, creating new splendor and helping open new vista for the International Communist Movement.

Residential environmental evaluation of local cities considering regional characteristic and personal residential preference—a case study of Saga City,Japan

Questionnaire surveys and subjective evaluations on residential environment were performed in order to grasp the main factors of residential environment of small local cities. The suitable evaluation index system was established, and the regional residential environment characteristics and personal residential preference types were analyzed, so that their influence on residential environment evaluation could be grasped. The results can be applied to the residential environment planning, construction and monitoring of local cities.

Comparison of the Bright Band Characteristics Measured by Micro Rain Radar (MRR) at a Mountain and a Coastal Site in South Korea

Data from a long term measurement of Micro Rain Radar （MRR） at a mountain site （Daegwallyeong, DG, one year period of 2005） and a coastal site （Haenam, HN, three years 2004-2006） in South Korea were analyzed to compare the MRR measured bright band characteristics of stratiform precipitation at the two sites. On average, the bright band was somewhat thicker and the sharpness （average gradient of reflectivity above and below the reflectivity peak） was slightly weaker at DG, compared to those values at HN. The peak reflectivity itself was twice as strong and the relative location of the peak reflectivity within the bright band was higher at HN than at DG. Importantly, the variability of these values was much larger at HN than at DG. The key parameter to cause these differences is suggested to be the difference of the snow particle densities at the two sites, which is related to the degree of riming. Therefore, it is speculated that the cloud microphysical processes at HN may have varied significantly from un-rimed snow growth, producing low density snow particles, to the riming of higher density particles, while snow particle growth at DG was more consistently affected by the riming process, and therefore high density snow particles. Forced uplifting of cloudy air over the mountain area around DG might have resulted in an orographic supercooling effect that led to the enhanced riming of supercooled cloud drops.

Numerical Study on Heat Transfer and Flow Characteristics for Laminar Flow in a Circular Tube with Swirl Generators

This study investigated the heat transfer and flow characteristics of one kind of swirlgenerator in a circular heat exchanger tube through a numericalsimulation. The swirlflow induced by this type of swirlgenerator can obtain a high heat transfer rate with minimalpressure drop penalty. The simulations were carried out to understand the physicalbehavior of this kind of mesoscale heat enhancement component. By visualizing the heat transfer and flow characteristics, it is found that the swirlflow is induced by swirlgenerator in the circular tube couples with the impinging jet effect. After passing through the swirlgenerator, the localfriction factor of liquid can quickly return to lower levelmore quickly, while the localNusselt number maintains higher values for a distance; thus, the evaluation criterion of localperformance is improved. Single-factor optimization is used for three geometric parameters, i.e., the angle of swirlgenerator(25o, 45o, and 60o), the length of swirlgenerator(0.005, 0.01, and 0.02 m), and the center rod radius(1, 2, and 3 mm). The optimum parameters of the swirlgenerator for laminar flow of air in a circular tube are obtained, which should be 60o, 0.005 m, and 3 mm, respectively.

Theory and Practice of Major Country Diplomacy with Chinese Characteristics:Inheritance, Innovation, and Development

As economic globalization and multi-polarization continue to develop worldwide,the international order is undergoing profound and complex changes,supporting more extensive peaceful development and instances of win-win cooperation.The collective rise of the emerging major countries is prompting the construction of a fair,rational new international order in politics and economy.In this context,China is a major force for world peace and the common development of the entire world,and the central leadership of the Chinese Communist Party(CCP),with Xi Jinping at its core has proposed a series of new concepts,modes of thinking,and strategies in relation to governance and administration,taking into account both the domestic and the international situation.Xi's perspective on diplomacy emerged from the theory and practice of major country diplomacy with Chinese characteristics and is the outcome of the combination of the universal principle of Marxism with the specific practice of major country diplomacy in China,and constitutes a major component of Xi's thought on socialism with Chinese characteristics in the new era.In his report to the 19th National Congress of the CCP,General Secretary Xi proposed to develop a community with a shared concept of the future for humanity to forge a new form of international relations,featuring mutual respect,fairness,justice,and win-win cooperation.1 This shows the constructive role China is playing in the peaceful development of the world,actively participating in and leading global governance and safeguarding the stability of the international order,thus laying the basis in discourse for the theory and practice of major country diplomacy with Chinese characteristics for a new era.

Characteristics and experience in the electrical design of the first domestically-integrated large-scale air separation unit

The first domestically-integrated large-scale air separation unit （ASU） with a capacity of 60 000 m^3/h was successfully built and put into operation at Baosteel. Compared with the electrical design of the imported equipment of the same type,this ASU has an electrical protection interlink that is independent from the distribution control system （DCS）. With the design idea of simplicity, the ASU features a simplified configuration and an audio alarm system for electrical failures. It helps reduce the failure rate of the electrical equipment and detect failures quickly and accurately. It will effectively enhance safe and stabilized production. The ASU can not only reduce the cost of investment, but also ensure a smooth and stable running of the whole electrical equipment. This study focuses on the experience and understanding of the unit design and commissioning.

Semen characteristics of the three genetic types of boars reared in Benin

Objective:To characterize the semen of three genetic types of boars(local,improved and Large White)reared in Benin.Methods:Semen of local,improved and Large White boars reared in Benin were collected using the gloved hand method and analyzed to determine volume,pH,concentration,mobility,motility,and morphology.The effect of the genetic type of boar on semen characteristics was aslo studied.Results:Duration of ejaculation and semen volume of Large White boar were significantly higher than those of local and improved boars(P<0.05).The semen of improved boars had a higher motility score than that of Large White and local boars(P<0.001).The semen of local boars was more concentrated in the spermatozoa than that of improved and Large White boars(P<0.05).The proportion of spermatozoa of improved boars with normal morphology(93.6%)was significantly higher than that of local(82.2%)and Large White boars(81.6%)(P<0.001).The proportion of spermatozoa with folded tails in the semen of Large White boars(9.2%)was significantly higher than that observed in improved(1.8%)and local(5.0%)boars(P<0.001).The proportion of spermatozoa with proximal cytoplasmic droplets in semen of improved boars(2.7%)was significantly lower than that in Large White(6.8%)and local(9.7%)boars(P<0.001).The local(1.5%)and Large White boars(1.1%)showed more spermatozoa with distal cytoplasmic droplets in their semen compared to the improved boars(0.4%).Conclusions:The semen characteristics of pigs reared in Benin vary from one genetic type to another.Each genetic type has a strong point.The Large White boar produces larger semen,the local boar produces more concentrated semen and the improved boar produces spermatozoa that are morphologically better.The semen of these three genetic types can be used in artificial insemination but the improved boar's semen is more recommended.

Growth Characteristics of <i>Fuirena umbellata</i>in a Surface Flow Constructed Wetland and Its Influence in Nutrients and Faecal Bacteria Removal from Domestic Wastewater in Cameroon

Various configurations of vegetated bed systems with a variety of macrophytes have been tested experimentally in Cameroon, for the treatment of domestic wastewater. The aim of this work was to assess the growth and biomass production of Fuirena umbellata (Cyperaceae) and its potentials in the removal of faecal bacteria and nutrients from primarily treated domestic effluent. A wetland vegetated with this macrophyte and a non-vegetated wetland (control) were continuously fed with primarily treated domestic wastewater at an estimated loading rate of 205 Litres/day in dry and rainy seasons for two consecutive years. Physicochemical and microbiological parameters of the effluent were monitored at the inflow and outflows of the wetlands alongside with the growth and productivity attributes of the young plants during each season. The density of plants ranged in the wetland from 17 - 185 plants/m2 and from 11 - 146 plants/m2 respectively during the first and the second years. More biomasses were instead produced in the dry seasons than in the rainy seasons but with no significant differences observed. As for nutrients removal, higher efficiencies were observed in the vegetated wetland (45% - 73%) compared to the non-vegetated control (17% - 66%). Similar trends were observed for the faecal bacteria but with no significant differences between the seasons. However, the vegetated beds were significantly more efficient than the non-vegetated control in the reduction of many physicochemical parameters and faecal bacteria. This varied with the seasons.

National Security Theory with Chinese Characteristics for a New Era

The COVID-19 pandemic has accelerated changes unseen in a century,ushering profound transitions in the development environment of China.The Central Committee of the Communist Party of China(CPC),with Comrade Xi Jinping at its core,maintains a firm hold on the strategic initiative in ensuring China’s security.It has developed new understandings and new ideas of the laws underlying national security,and emphasized the need to take a holistic approach to national security.This holistic approach is a powerful theoretical instrument that has become a fundamental guideline by incorporating China-specific characteristics to safeguarding and shaping national security.We must conscientiously study a holistic approach to national security to strengthen our consciousness of the need to keep in alignment with the Party Central Committee.We must closely follow the Party Central Committee in terms of our thinking,political orientation,and actions.We should put into practice Xi Jinping Thought on the Governance of China and implement the strategic decision to coordinate the needs of both development and security.We must remain committed to the principle of complying with China’s overall interests in ensuring both development and security as our nation marches toward rejuvenation.We must arm ourselves with Xi Jinping’s national security theory with Chinese characteristics for a new era and use it to guide our practices,thereby enhancing our professional abilities,quality,and methodologies to achieve levels commensurate with the requirements of a major and responsible country.We should adeptly align our efforts to the big picture of ensuring China’s national security in a holistic manner.