Although the current standard treatment for hepatocellular carcinoma(HCC) with portal vein tumor thrombosis(PVTT) is sorafenib, many previous studies have established the need for a reliable local modality for PVTT co...Although the current standard treatment for hepatocellular carcinoma(HCC) with portal vein tumor thrombosis(PVTT) is sorafenib, many previous studies have established the need for a reliable local modality for PVTT control, which is a major cause of liver function deterioration and metastasis. Additionally, there is growing evidence for the prognostic significance of PVTT classification according to the location of tumor thrombosis. Favorable outcomes can be obtained by applying local modalities, including surgery or transarterial chemoembolization, especially in second-order or distal branch PVTT. Rapid control of PVTT could maintain or improve liver function and reduce intrahepatic as well as distant metastasis. Radiotherapy(RT) is one of the main locoregional treatment modalities in oncologic fields, but has rarely been used in HCC because of concerns regarding hepatic toxicity. However, with the development of advanced techniques, RT has been increasingly applied in HCC management. Randomized studies have yet to definitively prove the benefit of RT, but several comparative studies have justified the application of RT in HCC. The value of RT is especially noticeable in HCC with PVTT; several prospective and retrospective studies have reported favorable outcomes, including a 40% to 60% objective response rate and median overall survival of 15 mo to 20 mo in responders. In this review, we evaluate the role of RT as an alternative local modality in HCC with PVTT.展开更多
This paper presents a two-phase genetic algorithm (TPGA) based on the multi- parent genetic algorithm (MPGA). Through analysis we find MPGA will lead the population' s evol vement to diversity or convergence accor...This paper presents a two-phase genetic algorithm (TPGA) based on the multi- parent genetic algorithm (MPGA). Through analysis we find MPGA will lead the population' s evol vement to diversity or convergence according to the population size and the crossover size, so we make it run in different forms during the global and local optimization phases and then forms TPGA. The experiment results show that TPGA is very efficient for the optimization of low-dimension multi-modal functions, usually we can obtain all the global optimal solutions.展开更多
Many multi-story or highrise buildings consisting of a number of identical stories are usually considered as periodic spring-mass systems. The general expressions of natural frequencies, mode shapes, slopes and curvat...Many multi-story or highrise buildings consisting of a number of identical stories are usually considered as periodic spring-mass systems. The general expressions of natural frequencies, mode shapes, slopes and curvatures of mode shapes of the periodic spring-mass system by utilizing the periodic structure theory are derived in this paper. The sensitivities of these mode parameters with respect to structural damages, which do not depend on the physical parameters of the original structures, are obtained. Based on the sensitivity analysis of these mode parameters, a two-stage method is proposed to localize and quantify damages of multi-story or highrise buildings. The slopes and curvatures of mode shapes, which are highly sensitive to local damages, are used to localize the damages. Subsequently, the limited measured natural frequencies, which have a better accuracy than the other mode parameters, are used to quantify the extent of damages within the potential damaged locations. The experimental results of a 3-story experimental building demonstrate that the single or multiple damages of buildings, either slight or severe, can be correctly localized by using only the slope or curvature of mode shape in one of the lower modes, in which the change of natural frequency is the largest, and can be accurately quantified by the limited measured natural frequencies with noise pollution.展开更多
针对自适应局部迭代滤波(Adaptive Local Iterative Filtering,ALIF)方法的模态混叠问题,提出了基于伪极值点的自适应局部迭代滤波(Pseudo-extrema-based Adaptive Local Iterative Filtering,PEALIF)方法.此方法采用增加伪极值点的方...针对自适应局部迭代滤波(Adaptive Local Iterative Filtering,ALIF)方法的模态混叠问题,提出了基于伪极值点的自适应局部迭代滤波(Pseudo-extrema-based Adaptive Local Iterative Filtering,PEALIF)方法.此方法采用增加伪极值点的方式使得信号极值点的分布更均匀,有效地抑制模态混叠问题的同时,亦保证了算法分解的顺序性.详细介绍了EPALIF方法的原理,同时构建仿真信号,将此方法与EMD、EEMD、CEEMD和ALIF方法进行分析和对比.结果表明PEALIF在分解能力、抑制模态混叠和抗噪声干扰等方面都具有一定的优越性.最后,将此方法应用在双半内圈轴承故障诊断中,实验结果表明PEALIF方法能获取更突出且易于辨识的故障特征信息,证实了该方法应用在轴承故障诊断分析上的实用性.展开更多
针对可见光-红外跨模态行人重识别中模态差异导致的识别精确率低的问题,提出了一种基于双流结构的跨模态行人重识别关系网络(IVRNBDS)。首先,利用双流结构分别提取可见光模态和红外模态行人图像的特征;然后,将行人图像的特征图水平切分...针对可见光-红外跨模态行人重识别中模态差异导致的识别精确率低的问题,提出了一种基于双流结构的跨模态行人重识别关系网络(IVRNBDS)。首先,利用双流结构分别提取可见光模态和红外模态行人图像的特征;然后,将行人图像的特征图水平切分为6个片段,以提取行人的每个片段的局部特征和其他片段的特征之间的关系,以及行人的核心特征和平均特征之间的关系;最后,在设计损失函数时,引入异质中心三元组损失(HC Loss)函数放松普通三元组损失函数的严格约束,从而使不同模态的图像特征可以更好地映射到同一特征空间中。在公开数据集SYSU-MM01(Sun Yat-Sen University Multi Modal re-identification)和Reg DB(Dongguk Body-based person Recognition)上的实验结果表明,虽然IVRNBDS的计算量略高于当前主流的跨模态行人重识别算法,但所提网络在相似度排名第1(Rank-1)指标和平均精度均值(m AP)指标上都有所提高,提高了跨模态行人重识别算法的识别精确率。展开更多
基金Supported by Samsung Medical Center,No.GF01130081Basic Science Research Program through the National Research Foundation of Korea funded by the Ministry of Education,No.NRF-2015R1D1A1A01060945Marine Biotechnology Program Funded by Ministry of Oceans and Fisheries,Korea,No.20150220
文摘Although the current standard treatment for hepatocellular carcinoma(HCC) with portal vein tumor thrombosis(PVTT) is sorafenib, many previous studies have established the need for a reliable local modality for PVTT control, which is a major cause of liver function deterioration and metastasis. Additionally, there is growing evidence for the prognostic significance of PVTT classification according to the location of tumor thrombosis. Favorable outcomes can be obtained by applying local modalities, including surgery or transarterial chemoembolization, especially in second-order or distal branch PVTT. Rapid control of PVTT could maintain or improve liver function and reduce intrahepatic as well as distant metastasis. Radiotherapy(RT) is one of the main locoregional treatment modalities in oncologic fields, but has rarely been used in HCC because of concerns regarding hepatic toxicity. However, with the development of advanced techniques, RT has been increasingly applied in HCC management. Randomized studies have yet to definitively prove the benefit of RT, but several comparative studies have justified the application of RT in HCC. The value of RT is especially noticeable in HCC with PVTT; several prospective and retrospective studies have reported favorable outcomes, including a 40% to 60% objective response rate and median overall survival of 15 mo to 20 mo in responders. In this review, we evaluate the role of RT as an alternative local modality in HCC with PVTT.
基金Supported by the National Natural Science Foundation of China (70071042,60073043,60133010)
文摘This paper presents a two-phase genetic algorithm (TPGA) based on the multi- parent genetic algorithm (MPGA). Through analysis we find MPGA will lead the population' s evol vement to diversity or convergence according to the population size and the crossover size, so we make it run in different forms during the global and local optimization phases and then forms TPGA. The experiment results show that TPGA is very efficient for the optimization of low-dimension multi-modal functions, usually we can obtain all the global optimal solutions.
基金Project supported by the National Natural Science Foundation of China (No. 50378041) Specialized Research Fund for Doctoral Programs of Higher Education (No. 20030487016).
文摘Many multi-story or highrise buildings consisting of a number of identical stories are usually considered as periodic spring-mass systems. The general expressions of natural frequencies, mode shapes, slopes and curvatures of mode shapes of the periodic spring-mass system by utilizing the periodic structure theory are derived in this paper. The sensitivities of these mode parameters with respect to structural damages, which do not depend on the physical parameters of the original structures, are obtained. Based on the sensitivity analysis of these mode parameters, a two-stage method is proposed to localize and quantify damages of multi-story or highrise buildings. The slopes and curvatures of mode shapes, which are highly sensitive to local damages, are used to localize the damages. Subsequently, the limited measured natural frequencies, which have a better accuracy than the other mode parameters, are used to quantify the extent of damages within the potential damaged locations. The experimental results of a 3-story experimental building demonstrate that the single or multiple damages of buildings, either slight or severe, can be correctly localized by using only the slope or curvature of mode shape in one of the lower modes, in which the change of natural frequency is the largest, and can be accurately quantified by the limited measured natural frequencies with noise pollution.
文摘针对自适应局部迭代滤波(Adaptive Local Iterative Filtering,ALIF)方法的模态混叠问题,提出了基于伪极值点的自适应局部迭代滤波(Pseudo-extrema-based Adaptive Local Iterative Filtering,PEALIF)方法.此方法采用增加伪极值点的方式使得信号极值点的分布更均匀,有效地抑制模态混叠问题的同时,亦保证了算法分解的顺序性.详细介绍了EPALIF方法的原理,同时构建仿真信号,将此方法与EMD、EEMD、CEEMD和ALIF方法进行分析和对比.结果表明PEALIF在分解能力、抑制模态混叠和抗噪声干扰等方面都具有一定的优越性.最后,将此方法应用在双半内圈轴承故障诊断中,实验结果表明PEALIF方法能获取更突出且易于辨识的故障特征信息,证实了该方法应用在轴承故障诊断分析上的实用性.
文摘针对可见光-红外跨模态行人重识别中模态差异导致的识别精确率低的问题,提出了一种基于双流结构的跨模态行人重识别关系网络(IVRNBDS)。首先,利用双流结构分别提取可见光模态和红外模态行人图像的特征;然后,将行人图像的特征图水平切分为6个片段,以提取行人的每个片段的局部特征和其他片段的特征之间的关系,以及行人的核心特征和平均特征之间的关系;最后,在设计损失函数时,引入异质中心三元组损失(HC Loss)函数放松普通三元组损失函数的严格约束,从而使不同模态的图像特征可以更好地映射到同一特征空间中。在公开数据集SYSU-MM01(Sun Yat-Sen University Multi Modal re-identification)和Reg DB(Dongguk Body-based person Recognition)上的实验结果表明,虽然IVRNBDS的计算量略高于当前主流的跨模态行人重识别算法,但所提网络在相似度排名第1(Rank-1)指标和平均精度均值(m AP)指标上都有所提高,提高了跨模态行人重识别算法的识别精确率。