Objective:This clinical study was performed to examine the influence of heat-producing acupuncture(HPA)treatment on the local skin temperature of Zusanli(足三里ST36)acupoint in healthy participants.Methods:30 healthy ...Objective:This clinical study was performed to examine the influence of heat-producing acupuncture(HPA)treatment on the local skin temperature of Zusanli(足三里ST36)acupoint in healthy participants.Methods:30 healthy participants received four successive sessions of heat-producing acupuncture(HPA),non-acupoint HPA(NAHPA),normal stable acupuncture(Norm)and non-invasive sham acupuncture(Sham)on the ST36 acupoint in random order.Within each treatment session,the local skin temperature of ST36 acupoint and basal body temperature of each participant were measured at 1 min before needle insertion(T1 B),just after needle insertion and manipulation(T0),5 min after needle insertion(T5)and 5 min after needle removal(T5 A).Visual Analogue Scale(VAS)scores of the participants’perceived needling and heat sensation felt during the acupuncture treatment period(T0-T5)were also recorded on a scale of 1 to 10.Results:Intra-session group statistical analyses of the different time points in the HPA treatment session group demonstrates that ST36 local skin temperature remained relatively stable between T1 B and T0,increased significantly between T0 and T5 and decreased significantly between T5 and T5 A.For intersession group statistical analysis of all treatment session groups,the increase in local skin temperature of ST36 acupoint between T0 and T5 in the HPA treatment session group was significantly higher than those of the NAHPA treatment session group(P<0.01),Norm treatment session group(P<0.01)and Sham treatment session group(P<0.01).The decrease in local skin temperature of ST36 acupoint between T5 and T5 A in the HPA treatment session group was also significantly more than those of NAHPA treatment session group(P<0.05),Norm treatment session group(P<0.01)and Sham treatment session group(P<0.001).Conclusion:Our study provides evidence that HPA treatment performed significantly better than the other three treatments in elevating the local skin temperature of ST36 acupoint temporarily.Our results also align with those of many previous clinical studies on HPA and related acupuncture manipulations.展开更多
Breast cancer is the second most common cause of cancer death in women in India in spite of advances in the adjuvant treatment of breast cancer. Locally advanced breast cancer (LABC) still represents the major present...Breast cancer is the second most common cause of cancer death in women in India in spite of advances in the adjuvant treatment of breast cancer. Locally advanced breast cancer (LABC) still represents the major presenting picture in many urban and rural institutions in our country. Skin Sparing Mastectomy (SSM) and primary reconstruction is a popular option for patients with breast cancer. There are similar local and distant recurrences in SSM compared to the traditional non-skin sparing mastectomy. A 57-year-old lady presented with a locally advanced left breast cancer. After undergoing neoadjuvant chemotherapy and a PET-CT to accurately detect residual disease in breast and axilla, she underwent skin sparing mastectomy with nipple-areola complex preservation and primary reconstruction with silicon prosthesis implant over a latissimus dorsi myocutaneous flap for primary reconstruction. SSM in LABC has not been reported in the literature so far. This patient is disease free for the past 24 months.展开更多
Darier-Ferrand dermatofibrosarcoma (DFS) is a cutaneous mesenchymal tumor of intermediate malignancy. It is a rare but not exceptional tumor, accounting for 0.1% of malignant skin tumors. Histological examination is e...Darier-Ferrand dermatofibrosarcoma (DFS) is a cutaneous mesenchymal tumor of intermediate malignancy. It is a rare but not exceptional tumor, accounting for 0.1% of malignant skin tumors. Histological examination is essential for diagnosis. Wide surgical excision is the standard treatment. DFS is a tumor whose prognosis and evolutionary risk are mainly linked to the delay in diagnosis and the quality of the first excision. Late diagnosis makes excision and reconstruction surgery difficult. The chances of recovery in the case of well-performed primary surgery are significantly greater than in the case of salvage surgery. To improve prognosis, early, codified, multidisciplinary management is essential. In our African context, and especially in the case of patients living in rural areas, errant diagnoses are often found hence the importance of raising awareness and providing information to healthcare personnel. We report a case of an enlarged left supraclavicular Darier-Ferrand dermatofibrosarcoma. The patient had come for a late consultation at a stage when the tumour was large. The CT scan was a great help in the pre-operative phase. The patient underwent complete surgical excision, the postoperative course was straightforward and the histology of the surgical specimen confirmed the diagnosis. The resection margins were healthy. The patient is alive at one year with no recurrence or metastasis.展开更多
文摘Objective:This clinical study was performed to examine the influence of heat-producing acupuncture(HPA)treatment on the local skin temperature of Zusanli(足三里ST36)acupoint in healthy participants.Methods:30 healthy participants received four successive sessions of heat-producing acupuncture(HPA),non-acupoint HPA(NAHPA),normal stable acupuncture(Norm)and non-invasive sham acupuncture(Sham)on the ST36 acupoint in random order.Within each treatment session,the local skin temperature of ST36 acupoint and basal body temperature of each participant were measured at 1 min before needle insertion(T1 B),just after needle insertion and manipulation(T0),5 min after needle insertion(T5)and 5 min after needle removal(T5 A).Visual Analogue Scale(VAS)scores of the participants’perceived needling and heat sensation felt during the acupuncture treatment period(T0-T5)were also recorded on a scale of 1 to 10.Results:Intra-session group statistical analyses of the different time points in the HPA treatment session group demonstrates that ST36 local skin temperature remained relatively stable between T1 B and T0,increased significantly between T0 and T5 and decreased significantly between T5 and T5 A.For intersession group statistical analysis of all treatment session groups,the increase in local skin temperature of ST36 acupoint between T0 and T5 in the HPA treatment session group was significantly higher than those of the NAHPA treatment session group(P<0.01),Norm treatment session group(P<0.01)and Sham treatment session group(P<0.01).The decrease in local skin temperature of ST36 acupoint between T5 and T5 A in the HPA treatment session group was also significantly more than those of NAHPA treatment session group(P<0.05),Norm treatment session group(P<0.01)and Sham treatment session group(P<0.001).Conclusion:Our study provides evidence that HPA treatment performed significantly better than the other three treatments in elevating the local skin temperature of ST36 acupoint temporarily.Our results also align with those of many previous clinical studies on HPA and related acupuncture manipulations.
文摘Breast cancer is the second most common cause of cancer death in women in India in spite of advances in the adjuvant treatment of breast cancer. Locally advanced breast cancer (LABC) still represents the major presenting picture in many urban and rural institutions in our country. Skin Sparing Mastectomy (SSM) and primary reconstruction is a popular option for patients with breast cancer. There are similar local and distant recurrences in SSM compared to the traditional non-skin sparing mastectomy. A 57-year-old lady presented with a locally advanced left breast cancer. After undergoing neoadjuvant chemotherapy and a PET-CT to accurately detect residual disease in breast and axilla, she underwent skin sparing mastectomy with nipple-areola complex preservation and primary reconstruction with silicon prosthesis implant over a latissimus dorsi myocutaneous flap for primary reconstruction. SSM in LABC has not been reported in the literature so far. This patient is disease free for the past 24 months.
文摘Darier-Ferrand dermatofibrosarcoma (DFS) is a cutaneous mesenchymal tumor of intermediate malignancy. It is a rare but not exceptional tumor, accounting for 0.1% of malignant skin tumors. Histological examination is essential for diagnosis. Wide surgical excision is the standard treatment. DFS is a tumor whose prognosis and evolutionary risk are mainly linked to the delay in diagnosis and the quality of the first excision. Late diagnosis makes excision and reconstruction surgery difficult. The chances of recovery in the case of well-performed primary surgery are significantly greater than in the case of salvage surgery. To improve prognosis, early, codified, multidisciplinary management is essential. In our African context, and especially in the case of patients living in rural areas, errant diagnoses are often found hence the importance of raising awareness and providing information to healthcare personnel. We report a case of an enlarged left supraclavicular Darier-Ferrand dermatofibrosarcoma. The patient had come for a late consultation at a stage when the tumour was large. The CT scan was a great help in the pre-operative phase. The patient underwent complete surgical excision, the postoperative course was straightforward and the histology of the surgical specimen confirmed the diagnosis. The resection margins were healthy. The patient is alive at one year with no recurrence or metastasis.