Locoweed is a poisonous plant wildly distributed in most area of the world and can cause livestock poisoning or death with significant economic loss. The principal responsible for its toxicity is indolizidine alkaloid...Locoweed is a poisonous plant wildly distributed in most area of the world and can cause livestock poisoning or death with significant economic loss. The principal responsible for its toxicity is indolizidine alkaloid swainsonine, a new potential anticancer and antiviral drug. Astragalus strictus is mainly distributed in Tibet of China and is a serious hazard to the local livestock industry. To analyze its main toxic ingredients and supply more structural information and more accurate data, swainsonine has been isolated from this plant by D101 macroporous resin and the ^1H and ^13C chemical shifts of the compound has been assigned by 1D-NMR and 2D-NMR techniques. At the same time, complete assignments of swainsonine＇s ^13C spectral signals are reported.展开更多
Locoweed is one of main poisonous plants in the world, and also is the most important toxic plant in grassland of China. The distribution range of the locoweed is extending continuously and it has formed or is coming ...Locoweed is one of main poisonous plants in the world, and also is the most important toxic plant in grassland of China. The distribution range of the locoweed is extending continuously and it has formed or is coming into dominant species gradually in some areas in recent years, which cause the retrogressive succession and grazer poisoning and died in rangeland. Locoweed seriously threatened the grassland agriculture and made typical 'ecology-economic sick' in above district. Based on the investigation, research, prevention and cure practice to the locoweed for more than ten years, this paper reviewed the present situation and prospect of the studies on the locoweed in China, which include the researches of it's biological characteristics, distribution, ecological environment, harmfulness, prevention, weeding, utilization and ecological control etc.展开更多
基金the National Natural Science Foundation of China (39770571)
文摘Locoweed is a poisonous plant wildly distributed in most area of the world and can cause livestock poisoning or death with significant economic loss. The principal responsible for its toxicity is indolizidine alkaloid swainsonine, a new potential anticancer and antiviral drug. Astragalus strictus is mainly distributed in Tibet of China and is a serious hazard to the local livestock industry. To analyze its main toxic ingredients and supply more structural information and more accurate data, swainsonine has been isolated from this plant by D101 macroporous resin and the ^1H and ^13C chemical shifts of the compound has been assigned by 1D-NMR and 2D-NMR techniques. At the same time, complete assignments of swainsonine＇s ^13C spectral signals are reported.
文摘Locoweed is one of main poisonous plants in the world, and also is the most important toxic plant in grassland of China. The distribution range of the locoweed is extending continuously and it has formed or is coming into dominant species gradually in some areas in recent years, which cause the retrogressive succession and grazer poisoning and died in rangeland. Locoweed seriously threatened the grassland agriculture and made typical 'ecology-economic sick' in above district. Based on the investigation, research, prevention and cure practice to the locoweed for more than ten years, this paper reviewed the present situation and prospect of the studies on the locoweed in China, which include the researches of it's biological characteristics, distribution, ecological environment, harmfulness, prevention, weeding, utilization and ecological control etc.
