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LD环状侧面均匀泵浦Nd∶YAG激光振荡器
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作者 韩昌昊 穆宇 +4 位作者 罗辉 韩隆 方聪 王思博 魏磊 《激光与红外》 CAS CSCD 北大核心 2024年第2期179-184,共6页
激光二极管(Laser Diode,LD)环状侧面均匀泵浦的激光振荡器具有结构简单、光束质量高、单脉冲能量大等特点,常常在高能脉冲固体激光器中作为主振荡功率放大(MOPA)结构的振荡器,一直是国内外科研人员研究的重要方向之一。本论文通过Zema... 激光二极管(Laser Diode,LD)环状侧面均匀泵浦的激光振荡器具有结构简单、光束质量高、单脉冲能量大等特点,常常在高能脉冲固体激光器中作为主振荡功率放大(MOPA)结构的振荡器,一直是国内外科研人员研究的重要方向之一。本论文通过Zemax软件对不同激光二极管排列方式以及不同工作物质吸收系数对吸收光场的影响的进行了仿真。基于仿真结果,设计了一种20个bar条串联的环状侧面泵浦结构,以提高晶体吸收的均匀性。通过该环状侧泵结构,结合超高斯非稳腔设计,搭建了一种双棒串接激光振荡器进行实验研究。该振荡器实现了在100 Hz重复频率下,单脉冲能量为496 mJ、脉冲宽度为12.4 ns的1064 nm激光输出,光束质量优于9 mm·mrad,光-光转换效率为18.5%。并且该振荡器可以维持光轴稳定不变的同时,实现20 ns脉宽以内变档可调。实验结果证明了该环状侧面均匀泵浦结构可靠有效,为MOPA结构振荡器选取提供了一种有效的方案。 展开更多
关键词 激光二极管 环状侧面泵浦 ndyag 振荡器 大脉冲能量
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Pulsed Nd:YAG laser cladding of high silicon content coating on low silicon steel 被引量:4
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作者 Danyang Dong Changsheng Liu Bin Zhang Jun Miao 《Journal of University of Science and Technology Beijing》 CSCD 2007年第4期321-326,共6页
A pulsed Nd:YAG (yttrium aluminum garnet) laser-based technique was employed to clad low silicon steel with preplaced Si and Fe mixed powders for high Si content. The surface morphology, microstructural evolution, ... A pulsed Nd:YAG (yttrium aluminum garnet) laser-based technique was employed to clad low silicon steel with preplaced Si and Fe mixed powders for high Si content. The surface morphology, microstructural evolution, phase composition, and Si distribution, within the obtained cladding coatings, were characterized by optical microscopy (OM), field emission scanning electron microscopy (FE-SEM), with associated energy dispersive spectroscopy (EDS), transmission electron microscopy (TEM), and X-ray diffraction (XRD). The microhardness was also measured along the depth direction of the specimens, A crack- and pore-free cladding coating through excellent metallurgical bonding with the substrate was successfully prepared on low silicon steel by means of optimized single-track and multi-track laser cladding. The phases of the coating are a-Fe, T-Fe, and FeSi. The high microhardness of the lasercladding zone is considered as an increase in Si content and as the refined microstructure produced by the laser treatment. The Si contents of the cladding coatings were about 5.8wt% in the single-track cladding and 6.5wt% in the multi-track cladding, respectively. 展开更多
关键词 silicon steel pulsed ndyag laser cladding high silicon content coating MICROSTRUCTURE MICROHARDNESS
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Controlled Laser Transformation Hardening of Martensitic Stainless Steel by Pulsed Nd:YAG Laser 被引量:2
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作者 B.Mahmoudi A.R.Sabour Aghdam M.J.Torkamany 《Journal of Electronic Science and Technology of China》 2010年第1期87-90,共4页
Laser transformation hardening (LTH) was applied to the surface of the AISI 420 martensitic stainless steel by a pulsed Nd:YAG laser to obtain optimum hardness. The influences of process parameters (laser pulse en... Laser transformation hardening (LTH) was applied to the surface of the AISI 420 martensitic stainless steel by a pulsed Nd:YAG laser to obtain optimum hardness. The influences of process parameters (laser pulse energy, duration time, and travel speed) on the depth and hardness of laser treated area were investigated. Image analysis of SEM microstructure of AISI 420 showed that plate-like carbide have almost fully and (30-40)% of globular carbide particles dissolved into the matrix after laser transformation hardening by pulsed laser and the microstructure was refined to obtain controlled tempered martensite microstructure with 450 VHN hardness. 展开更多
关键词 laser transformation hardening martensitic stainless steel martensite microstructure pulsed ndyag laser.
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A 526 mJ Subnanosecond Pulsed Hybrid-Pumped Nd:YAG Laser
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作者 石江鹏 辛建国 +2 位作者 刘军 陈家斌 Sher Zaman 《Chinese Physics Letters》 SCIE CAS CSCD 2017年第7期105-108,共4页
A hybrid-pumped Nd:YAG pulse laser with a double-pass two-rod configuration is presented. The focal length of offset lens is particularly studied to compensate for the thermal lens effect and depolarization. For inpu... A hybrid-pumped Nd:YAG pulse laser with a double-pass two-rod configuration is presented. The focal length of offset lens is particularly studied to compensate for the thermal lens effect and depolarization. For input pulse energy of 141 μJ with pulse duration of 754ps, the pulse laser system delivers 526mJ pulse energy and 728ps pulse width output at lO Hz with pulse profile shape preservation. The energy stability of the laser pulse is less than 3%, and the beam quality factor M2 is less than 2.26. 展开更多
关键词 yag length A 526 mJ Subnanosecond pulsed Hybrid-Pumped nd:yag laser nd
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Nd:YAG 1064 nm激光与超脉冲点阵CO_(2)激光治疗面部萎缩性痤疮瘢痕美学效果对比研究 被引量:2
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作者 丁秀敏 谢君 +1 位作者 张志英 孙耀辉 《中国美容医学》 CAS 2023年第6期86-89,共4页
目的:探讨Nd:YAG 1064 nm激光与超脉冲点阵CO_(2)激光治疗面部萎缩性痤疮瘢痕美学效果。方法:选择2018年1月-2021年1月笔者医院收治的94例患者,按照随机数字表法分为对照组(47例)与研究组(47例)。对照组接受Nd:YAG 1064 nm激光治疗;研... 目的:探讨Nd:YAG 1064 nm激光与超脉冲点阵CO_(2)激光治疗面部萎缩性痤疮瘢痕美学效果。方法:选择2018年1月-2021年1月笔者医院收治的94例患者,按照随机数字表法分为对照组(47例)与研究组(47例)。对照组接受Nd:YAG 1064 nm激光治疗;研究组接受超脉冲点阵CO_(2)激光治疗。比较两组临床疗效、愈合时间、误工时间、温哥华瘢痕量表(Vancouver scar scale,VSS)评分及不良反应。结果:研究组治疗总有效率95.74%,较对照组80.85%高(P<0.05);研究组结痂时间、完全脱痂时间均比对照组短(P<0.05);研究组治疗后柔软度、色泽、血管分布、厚度评分均低于对照组(P<0.05);研究组治疗后社会功能、自我感知、痤疮症状评分高于对照组(P<0.05);两组不良反应总发生率相比无差异(P>0.05)。结论:相比Nd:YAG 1064 nm激光,超脉冲点阵CO_(2)激光治疗面部萎缩性痤疮瘢痕可以明显缩短患者愈合时间,更好改善瘢痕,美学效果更佳。 展开更多
关键词 面部痤疮 萎缩性瘢痕 超脉冲二氧化碳激光 nd:yag激光 疗效
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倍舒痕硅凝胶联合长脉宽1064 nm Nd∶YAG激光治疗面部烧伤后色素沉着 被引量:1
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作者 赵文利 石雪芹 +3 位作者 邹晓梅 侯宏义 胡晓龙 谢松涛 《中国美容医学》 CAS 2023年第7期90-93,共4页
目的:分析倍舒痕硅凝胶联合长脉宽1 064 nm Nd∶YAG激光治疗面部烧伤后色素沉着的效果。方法:选取2018年7月-2020年11月于笔者医院就诊的106例面部烧伤后色素沉着患者,以随机数字表法分为观察组和对照组,各53例。对照组接受单纯倍舒痕... 目的:分析倍舒痕硅凝胶联合长脉宽1 064 nm Nd∶YAG激光治疗面部烧伤后色素沉着的效果。方法:选取2018年7月-2020年11月于笔者医院就诊的106例面部烧伤后色素沉着患者,以随机数字表法分为观察组和对照组,各53例。对照组接受单纯倍舒痕硅凝胶外涂治疗,观察组在对照组基础上联合长脉宽1 064 nm Nd∶YAG激光治疗。比较两组治疗前、治疗2个月及治疗后的面部色素沉着面积评分及严重程度评分;比较两组患者治疗后6个月的临床疗效及满意度;记录两组治疗期间不良反应发生情况。结果:两组治疗前面部色素沉着面积评分及严重程度评分比较差异无统计学意义(P>0.05),治疗2个月及治疗后两组上述评分呈下降趋势,且观察组显著低于同时间点对照组(P<0.05);治疗后6个月观察组临床疗效优于对照组(P<0.05);观察组治疗后6个月的色素沉着改善评分显著高于对照组(P<0.05),两组治疗满意度总分比较差异无统计学意义(P>0.05);治疗过程中,所有患者均可耐受疼痛,观察组部分患者局部出现红肿、水疱,均于2~3 d后自行消退。结论:倍舒痕硅凝胶联合长脉宽1 064 nm Nd∶YAG激光治疗面部烧伤后色素沉着效果显著,安全性高。 展开更多
关键词 倍舒痕硅凝胶 长脉宽1064 nm ndyag激光 烧伤 色素沉着 临床疗效 满意度
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Nd∶YAG脉冲式激光联合重组人碱性成纤维细胞生长因子治疗复发性唇疱疹的效果
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作者 周丽静 戴东晓 石亚红 《中国医药导报》 CAS 2023年第25期99-102,共4页
目的评价Nd∶YAG脉冲式激光联合重组人碱性成纤维细胞生长因子(rh-bFGF)治疗复发性唇疱疹的效果。方法选取2020年1月至2021年2月石家庄市第二医院就诊的94例复发性唇疱疹患者,采用随机数字表法将其分为对照组与观察组,每组47例。对照组... 目的评价Nd∶YAG脉冲式激光联合重组人碱性成纤维细胞生长因子(rh-bFGF)治疗复发性唇疱疹的效果。方法选取2020年1月至2021年2月石家庄市第二医院就诊的94例复发性唇疱疹患者,采用随机数字表法将其分为对照组与观察组,每组47例。对照组予以单纯Nd∶YAG脉冲式激光治疗,观察组实施Nd∶YAG脉冲式激光联合rh-bFGF治疗。比较两组临床疗效、创面愈合状况[温哥华瘢痕量表(VSS)评分、疱疹消失时间、创面愈合时间及结痂脱落时间];比较两组治疗前后血浆转化生长因子-β_(1)(TGF-β_(1))、碱性成纤维细胞生长因子(bFGF)、血管内皮生长因子(VEGF)、巨噬细胞炎性蛋白-1(MIP-1)、单核细胞趋化蛋白-1(MCP-1)、Toll样受体(TLR)2及TLR9水平。结果观察组临床疗效优于对照组,差异有统计学意义(P<0.05)。观察组VSS评分低于对照组,疱疹消失时间、创面愈合时间及结痂脱落时间短于对照组,差异有统计学意义(P<0.05)。治疗后,两组血浆TGF-β_(1)、bFGF、VEGF水平高于治疗前,且观察组高于对照组,差异有统计学意义(P<0.05)。治疗后,两组血浆MIP-1、MCP-1、TLR2、TLR9水平低于治疗前,且观察组低于对照组,差异有统计学意义(P<0.05)。结论Nd∶YAG脉冲式激光联合rh-bFGF治疗复发性唇疱疹的效果确切,可促进创面愈合,其机制与促进TGF-β_(1)、bFGF、VEGF的生成,抑制MIP-1、MCP-1、TLR2、TLR9的生成,消除局部炎症有关。 展开更多
关键词 ndyag脉冲式激光 重组人碱性成纤维细胞生长因子 复发性唇疱疹
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Clinical usefulness of transpapillary removal of common bile duct stones by frequency doubled double pulse Nd:YAG laser 被引量:20
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作者 Tae Hyeon Kim Hyo Jeong Oh +2 位作者 Chang-Soo Choi Dong Han Yeom Suck Chei Choi 《World Journal of Gastroenterology》 SCIE CAS CSCD 2008年第18期2863-2866,共4页
AIM: To study the efficacy and the safety of laser lithotripsy without direct visual control by using a balloon catheter in patients with bile duct stones that could not be extracted by standard technique. METHODS: Th... AIM: To study the efficacy and the safety of laser lithotripsy without direct visual control by using a balloon catheter in patients with bile duct stones that could not be extracted by standard technique. METHODS: The seventeen patients (7 male and 10 female; mean age 67.8 years) with difficult common bile duct (CBD) stones were not amenable for conventional endoscopic maneuvers such as sphincterotomy and mechanical lithotripsy were included in this study. Laser wavelengths of 532 nm and 1064 nm as a double pulse were applied with pulse energy of 120 mJ. The laser fiber was advanced under fluoroscopic control through the ERCP balloon catheter. Laser lithotripsy was continued until the fragment size seemed to be less than 10 mm. Endoscopic extraction of the stones and fragments was performed with the use of the Dormia basket and balloon catheter. RESULTS: Bile duct clearance was achieved in 15 of 17 patients (88%). The mean number of treatment sessions was 1.7 ± 0.6. Endoscopic stone removal could not be achieved in 2 patients (7%). Adverse effects were noted in three patients (hemobilia, pancreatitis, and cholangitis). CONCLUSION: The Frequency Doubled Double Pulse Nd:YAG (FREDDY) laser may be an effective and safe technique in treatment of difficult bile duct stones. 展开更多
关键词 Bile duct stones Frequency doubled double pulse ndyag laser Transpapillary removal Mechanical lithotripsy Balloon catheter
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Microstructure,properties and first principles calculation of titanium alloy/steel by Nd: YAG laser self-fluxing welding 被引量:11
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作者 Zhang Yifu Zhang Hua +1 位作者 Zhu Zhengqiang Pan Jiluan 《China Welding》 EI CAS 2018年第3期1-10,共10页
The experiment of Nd: YAG pulsed laser self-fluxing welding for 304 stainless steel/Ti6Al4V titanium alloy dissimilar metal was carried out. The microstructure properties of welded joint were analyzed by SEM, EDS and... The experiment of Nd: YAG pulsed laser self-fluxing welding for 304 stainless steel/Ti6Al4V titanium alloy dissimilar metal was carried out. The microstructure properties of welded joint were analyzed by SEM, EDS and XRD. The equilibrium lattice constants, enthalpies of formation, cohesive energies, mechanical properties, Debye temperatures and valence electron structures of Ti-Fe intermetallic compounds (IMCs) were calculated by the first principle pseudopotential plane wave method based on density functional theory (DFT). According to the thermodynamic data of Ti-Fe-Cr compounds, the Gibbs free energy per mole of compound at different temperatures was calculated and their thermal stability was compared. The results show that there are no macroscopic cracks in the welded joints, and the IMCs distributed evenly along the welding interface exhibits 3 distinct layers of microstructure with different colors. The welds interface generates IMCs of TiFe, TiFe 2 and a small amount of Ti 5Cr 7Fe 17 IMCs. Ti-Fe IMCs with high thermodynamic stability and easy alloying formation. The results of Gibbs free energies show that the sequence of precipitates in the interface is Ti 5Cr 7Fe 17 , TiFe 2 and TiFe in high temperature during the metallurgical reaction. The G/B values of Ti-Fe IMCs are greater than the critical value of 0.5, indicating that it is an intrinsic brittleness. 展开更多
关键词 ndyag pulsed laser self-fluxing welding titanium alloy stainless steel first-principle calculation
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Diode end-pumped self-Q-switched and mode-locked Nd,Cr:YAG /KTP green laser 被引量:2
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作者 杜仕峰 王素梅 +5 位作者 张东香 冯宝华 张春雨 张玲 张治国 张世文 《Chinese Physics B》 SCIE EI CAS CSCD 2006年第7期1522-1525,共4页
We first experimentally demonstrate a laser-diode end-pumped self-Q-switched and mode-locked Nd,Cr:YAG green laser with a KTP crystal as the intra-cavity frequency doubler. The device produces an average output power... We first experimentally demonstrate a laser-diode end-pumped self-Q-switched and mode-locked Nd,Cr:YAG green laser with a KTP crystal as the intra-cavity frequency doubler. The device produces an average output power of 680 mW at 532 nm. The corresponding pulse width of the Q-switched envelope of the green laser is 170 + 20 ns. The mode-locked pulses have a repetition rate of approximately 183 MHz and the average pulse duration is estimated to be around sub-nanosecond. It is found that the intra-cavity frequency doubling greatly improves the modulation depth and stability of the mode-locked pulses within the Q-switched envelope. 展开更多
关键词 frequency doubling nd Cr:yag crystal self-Q-switched and mode-locked pulses green laser
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Effects of output waveforms on penetration for Nd :YAG laser welding 被引量:1
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作者 王家淳 沈剑韵 王希哲 《China Welding》 EI CAS 2000年第1期67-77,共11页
By using a Nd: YAG laser welding system devised for transmitting continuous, rectangular and pulsed waveforms, comprehensive and deep investigation is focused on the effects of several parameters of rectangular wavefo... By using a Nd: YAG laser welding system devised for transmitting continuous, rectangular and pulsed waveforms, comprehensive and deep investigation is focused on the effects of several parameters of rectangular waveform and pulsed output wave superimposed on a rectangular waveform on the penetration depth of weld. Research results indicate that the average power, duty cycle, frequency and peak power of rectangular wave affect the weld penetration depth to different extent. Results of experiments and analysis also indicate that the pulse delay time, pulse width and the power ratio of pulse to rectangular waveform seriously influence the penetration when the pulsed wave is superimposed on a rectangular waveform. 展开更多
关键词 nd: yag laser welding output waveform PENETRATION rectangular waveform pulsed wave
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Microstructure and properties of Nd:YAG laser welded AZ31B magnesium alloy 被引量:1
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作者 Cui Zeqin Cheng Linxin +2 位作者 Si En Wang Wenxian Xu Bingshe 《China Welding》 EI CAS 2014年第2期29-35,共7页
Biodegradable magnesium-based alloys are very promising materials for temporary implants. Laser welding is an important joining method in such application. In this study, the as-rolled AZ31B magnesium alloy sheets of ... Biodegradable magnesium-based alloys are very promising materials for temporary implants. Laser welding is an important joining method in such application. In this study, the as-rolled AZ31B magnesium alloy sheets of 1 mm in thickness were successfully joined by Nd : YAG laser welding. The microstructure and properties of the welded joint were investigated. The result shows that the welded joint is characterized by a narrow heat-affected zone, finer grains and a large number of precipitates distribute in the matrix in the weld. Microhardness of the weld is significantly improved to 72 HV 0. 05 as compared to 55 HV 0. 05 of the base metal. Tensile strength of butt-welded joint is 180. 24 MPa, which is 76. 8% that of the base metal. The electrochemical corrosion experiment shows that the corrosion resistance of laser welded joint is significantly improved in a 3.5 wt. % NaCl solution. 展开更多
关键词 AZ31 B Mg alloy sheet laser welding ndyag pulsed laser welded joint
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Pump pulse characteristics of quasi-continuous-wave diode-side-pumped Nd:YAG laser
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作者 Zexin Song Qi Bian +5 位作者 Yu Shen Keling Gong Nan Zong Qingshuang Zong Yong Bo Qinjun Peng 《Chinese Physics B》 SCIE EI CAS CSCD 2022年第5期355-359,共5页
The influence of pumping laser pulse on the property of quasi-continuous-wave(QCW)diode-side-pumped Nd:YAG laser is investigated theoretically and experimentally.Under remaining a fixed duty cycle,the average output p... The influence of pumping laser pulse on the property of quasi-continuous-wave(QCW)diode-side-pumped Nd:YAG laser is investigated theoretically and experimentally.Under remaining a fixed duty cycle,the average output power increases,and the corresponding thermal focal length shorten with the increase of the pump pulse duration,which attributes to the decrease of the ratio of pulse buildup time to the pulse duration.At a pump power of 146 W,the laser output power changes from 65.1 W to 81.2 W when the pulse duration is adjusted from 150μs to 1000μs,confirming a significant enhancement of 24.7%.A laser rate equation model incorporating the amplified spontaneous emission is also utilized and numerically solved,and the simulated results agree well with the experimental data. 展开更多
关键词 pump pulse duration DIODE-SIDE-PUMPED pulsed nd:yag laser laser rate equation amplified spontaneous emission
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Opto-Electronic Investigation of Wet Coating Deposition of ITO Nanopowders on Flexible Substrate Using Pulse Nd-YAG Laser
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作者 H. Salar-Amoli H. Amani 《Optics and Photonics Journal》 2013年第4期300-303,共4页
Transparent thin layer indium tin oxide was coated on polyethylene tetraphetalate (PET) substrate by means of spin coating process and its opto-electronic properties have been investigated. The surface treated by puls... Transparent thin layer indium tin oxide was coated on polyethylene tetraphetalate (PET) substrate by means of spin coating process and its opto-electronic properties have been investigated. The surface treated by pulse Nd-YAG laser. Pulse frequency, duration and energy were, 1000 Hz, 0.2 to 20 ms and 25 to 40 J respectively. The effect of treatment on crystallization, optical properties and bonding processes of the thin layer was investigated. The results show that ITO coated on flexible PET substrates is conductive and transparent. The sheet transparency for a 350 nm thickness in the visible range is more than 83.6%. Using Nd-YAG laser increased conductivity by a factor of 100 times and causes higher bonding performances. 展开更多
关键词 PULSE nd-yag laser PET SPIN Coating Flexible Substrate Opto-Electronic
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长脉宽Nd:YAG激光1064nm治疗甲真菌病33例临床观察 被引量:9
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作者 邹彦芬 叶庭路 +3 位作者 钟绮丽 秦晓蕾 李玉红 于波 《中国皮肤性病学杂志》 CAS 北大核心 2014年第6期581-583,共3页
目的探讨长脉宽Nd:YAG激光1 064nm治疗甲真菌病的临床疗效及安全性。方法用长脉宽1 064nm Nd:YAG激光治疗33例甲真菌病患者共计48个病甲,1次/周,4次为1个疗程,共治疗2~3个疗程。治疗参数:能量密度35~40J/cm2,脉宽30ms,光斑5mm,频率1H... 目的探讨长脉宽Nd:YAG激光1 064nm治疗甲真菌病的临床疗效及安全性。方法用长脉宽1 064nm Nd:YAG激光治疗33例甲真菌病患者共计48个病甲,1次/周,4次为1个疗程,共治疗2~3个疗程。治疗参数:能量密度35~40J/cm2,脉宽30ms,光斑5mm,频率1Hz。随访6~9个月,根据患者的临床表现及甲屑真菌镜检及培养结果判定疗效,并记录不良反应。结果 48个病甲中,临床疗效标准:治疗结束后6个月时有效率为70.83%,9个月时有效率为81.25%;按真菌学标准:治愈率分别为75.00%和87.50%。患者均有轻微疼痛,无严重不良反应。4例出现轻微的甲下出血,数周后自愈。结论长脉宽Nd:YAG激光1 064nm治疗甲真菌病安全而高效,值得临床选用。 展开更多
关键词 甲真菌病 长脉宽nd yag激光1 064nm 治疗 临床观察
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脉冲Nd:YAG激光联合3M粘接剂对牙本质小管封闭作用的体外研究 被引量:7
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作者 王彬娉 杨宾 +4 位作者 吴卓骏 陈奕苗 王秀丽 陆丽英 郁豆 《口腔医学研究》 CAS CSCD 2014年第8期722-723,727,共3页
目的:探讨脉冲Nd:YAG激光与3M粘接剂联合应用对牙本质小管封闭作用。方法:扫描电镜下观察脉冲Nd:YAG激光照射及脉冲Nd:YAG激光与3M粘接剂联合应用后,牙本质小管的形态学变化。结果:激光组牙本质表面小管口部分熔融封闭,联合应用组牙本... 目的:探讨脉冲Nd:YAG激光与3M粘接剂联合应用对牙本质小管封闭作用。方法:扫描电镜下观察脉冲Nd:YAG激光照射及脉冲Nd:YAG激光与3M粘接剂联合应用后,牙本质小管的形态学变化。结果:激光组牙本质表面小管口部分熔融封闭,联合应用组牙本质表面熔融,有白色均质样物质附着,部分牙本质小管口的形态模糊不清;纵断面激光组牙本质小管内呈现不规则的熔融改变,深度不深;联合组牙本质小管内可见明显树脂突,且深度较长。结论:激光与3M粘接剂联合应用具有良好的牙本质小管封闭作用。 展开更多
关键词 脉冲nd yag激光 3M粘接剂 牙本质小管
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点阵CO_2激光和Nd:YAG激光对自然老化小鼠皮肤MMP-1与TIMP-1表达的影响 被引量:4
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作者 李蕊联 应朝霞 +6 位作者 王冰 马慧群 刘艳 王永贤 王梅 张淑兰 周俊 《中国皮肤性病学杂志》 CAS 北大核心 2013年第5期449-453,共5页
目的探讨点阵CO2激光和Nd:YAG激光(准长脉宽1064nm波长)照射对自然老化小鼠皮肤基质金属蛋白酶-1(MMP-1)、基质金属蛋白酶组织抑制剂-1(TIMP-1)表达的影响,并进一步探讨其嫩肤机制。方法用点阵CO2激光和Nd:YAG激光照射小鼠背部脱毛皮肤... 目的探讨点阵CO2激光和Nd:YAG激光(准长脉宽1064nm波长)照射对自然老化小鼠皮肤基质金属蛋白酶-1(MMP-1)、基质金属蛋白酶组织抑制剂-1(TIMP-1)表达的影响,并进一步探讨其嫩肤机制。方法用点阵CO2激光和Nd:YAG激光照射小鼠背部脱毛皮肤每间隔10天1次,连续4次,分别在照射后2周、1个月及3个月取材,用免疫组化法检测MMP-1和TIMP-1的表达并观察其动态变化。结果点阵CO2激光和Nd:YAG激光照射区MMP-1和TIMP-1阳性表达,以2周时最明显:点阵CO2激光照射区MMP-1灰度值(115.14±5.23)与TIMP-1灰度值(104.01±3.15)均低于Nd:YAG激光照射区MMP-1灰度值(121.75±4.39)与TIMP-1灰度值(109.26±3.88),即点阵CO2激光照射区阳性表达较高,差异有统计学意义(P<0.05)。TIMP-1从总体水平上强于MMP-1的表达。结论点阵CO2激光和Nd:YAG激光照射促进MMP-1和TIMP-1表达增加,提示其直接参与了真皮重塑,点阵CO2激光组较Nd:YAG激光组效果明显。 展开更多
关键词 点阵CO2激光 nd yag激光(准长脉宽1 064nm波长) MMP-1 TIMP-1
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可调脉宽倍频Nd:YAG激光和积雪草苷对增生性瘢痕的疗效比较 被引量:14
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作者 吴东辉 谭军 +2 位作者 钟茜 罗明灿 李波 《中国美容整形外科杂志》 CAS 2008年第2期103-105,共3页
目的通过比较可调脉宽倍频Nd:YAG激光和积雪草苷对增生性瘢痕的疗效,探讨可调脉宽倍频Nd:YAG激光治疗增生性瘢痕的优越性。方法将164例增生性瘢痕患者随机分成A、B两组。A组患者为118例,采用可调脉宽倍频Nd:YAG激光进行治疗,并根据瘢痕... 目的通过比较可调脉宽倍频Nd:YAG激光和积雪草苷对增生性瘢痕的疗效,探讨可调脉宽倍频Nd:YAG激光治疗增生性瘢痕的优越性。方法将164例增生性瘢痕患者随机分成A、B两组。A组患者为118例,采用可调脉宽倍频Nd:YAG激光进行治疗,并根据瘢痕的厚度和颜色及患者正常皮肤颜色和个体差异,选择脉宽10~40ms和能量密度12~32J/cm2进行治疗,治疗1~3次,每次间隔1~3个月;B组患者为46例,采用积雪草苷霜进行治疗,将积雪草苷霜外涂于瘢痕处,每日2次,并局部按摩,一个疗程为3个月,共2~3个疗程。结果治疗后随访患者3~8个月。A组:显效者75例,有效者35例,无效者8例;B组:显效者5例,有效者28例,无效者13例。结论可调脉宽倍频Nd:YAG激光对增生性瘢痕具有较好的疗效,与积雪草苷比较有起效快、疗效好、效果稳定等优越性。 展开更多
关键词 增生性瘢痕 可调脉宽倍频nd:yag激光 积雪草苷 疗效比较
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高功率高光束质量脉冲Nd:YAG激光器 被引量:5
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作者 王宝华 李强 +2 位作者 姜梦华 惠勇凌 雷訇 《强激光与粒子束》 EI CAS CSCD 北大核心 2009年第5期663-666,共4页
以实现高功率、高光束质量的脉冲激光输出为目的,对非对称平-凹谐振腔的结构进行了理论分析。设计出了高功率、高光束质量非对称放置的平-凹谐振腔、双氙灯泵浦的脉冲Nd:YAG激光器。当占空比为9%时,实现输出激光平均功率近480 W,光束参... 以实现高功率、高光束质量的脉冲激光输出为目的,对非对称平-凹谐振腔的结构进行了理论分析。设计出了高功率、高光束质量非对称放置的平-凹谐振腔、双氙灯泵浦的脉冲Nd:YAG激光器。当占空比为9%时,实现输出激光平均功率近480 W,光束参数积优于12.7 mm.mrad,电光转化效率近4%,与理论分析吻合,可用芯径300μm的光纤传输,不稳定性优于±1%。加工实验证明有较好的质量:切割材料为不锈钢,厚度为3 mm时、切割速度为0.6 m/min和厚度为1.5 mm、切割速度为1.2 m/min时,两种情况下所得切缝宽度均为250μm,且切割上下沿光滑。 展开更多
关键词 脉冲固体激光器 nd:yag激光器 谐振腔 热焦距 光束质量
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Nd:YAG激光打标工艺试验研究 被引量:12
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作者 伍珊红 齐军 +1 位作者 虞孝舜 方鸣岗 《激光与红外》 CAS CSCD 北大核心 1999年第2期92-95,共4页
介绍了用NdYAG激光对不锈钢材料的打标工艺试验及其结果。论述了激光与金属材料的作用机理,着重分析了激光功率、重复频率、扫描速度等参数对标记质量的影响。
关键词 nd:yag激光器 激光打标 激光加工
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