The linear and nonlinear simulations are carried out using the gyrokinetic code NLT for the electrostatic instabilities in the core region of a deuterium plasma based on the International Thermonuclear Experimental Re...The linear and nonlinear simulations are carried out using the gyrokinetic code NLT for the electrostatic instabilities in the core region of a deuterium plasma based on the International Thermonuclear Experimental Reactor(ITER)baseline scenario.The kinetic electron effects on the linear frequency and nonlinear transport are studied by adopting the adiabatic electron model and the fully drift-kinetic electron model in the NLT code,respectively.The linear simulations focus on the dependence of linear frequency on the plasma parameters,such as the ion and electron temperature gradientsκ_(Ti,e)≡R=L_(Ti,e),the density gradientκ_(n)≡R/L_(n)and the ion-electron temperature ratioτ=T_(e)=T_(i).Here,is the major radius,and T_(e)and T_(i)denote the electron and ion temperatures,respectively.L_(A)=-(δ_(r)lnA)^(-1)is the gradient scale length,with denoting the density,the ion and electron temperatures,respectively.In the kinetic electron model,the ion temperature gradient(ITG)instability and the trapped electron mode(TEM)dominate in the small and large k_(θ)region,respectively,wherek_(θ)is the poloidal wavenumber.The TEMdominant region becomes wider by increasing(decreasing)κ_(T_(e))(κ_(T_(i)))or by decreasingκ_(n).For the nominal parameters of the ITER baseline scenario,the maximum growth rate of dominant ITG instability in the kinetic electron model is about three times larger than that in the adiabatic electron model.The normalized linear frequency depends on the value ofτ,rather than the value of T_(e)or T_(i),in both the adiabatic and kinetic electron models.The nonlinear simulation results show that the ion heat diffusivity in the kinetic electron model is quite a lot larger than that in the adiabatic electron model,the radial structure is finer and the time oscillation is more rapid.In addition,the magnitude of the fluctuated potential at the saturated stage peaks in the ITGdominated region,and contributions from the TEM(dominating in the higher k_(θ)region)to the nonlinear transport can be neglected.In the adiabatic electron model,the zonal radial electric field is found to be mainly driven by the turbulent energy flux,and the contribution of turbulent poloidal Reynolds stress is quite small due to the toroidal shielding effect.However,in the kinetic electron model,the turbulent energy flux is not strong enough to drive the zonal radial electric field in the nonlinear saturated stage.The kinetic electron effects on the mechanism of the turbulence-driven zonal radial electric field should be further investigated.展开更多
Clinical practice guidelines drive clinical practice and clinicians rely to them when trying to answer their most common questions.One of the most important position papers in the field of gastro-esophageal reflux dis...Clinical practice guidelines drive clinical practice and clinicians rely to them when trying to answer their most common questions.One of the most important position papers in the field of gastro-esophageal reflux disease(GERD)is the one produced by the Lyon Consensus.Recently an updated second version has been released.Mean nocturnal baseline impedance(MNBI)was proposed by the first Consensus to act as supportive evidence for GERD diagnosis.Originally a cut-off of 2292 Ohms was proposed,a value revised in the second edition.The updated Consensus recommended that an MNBI<1500 Ohms strongly suggests GERD while a value>2500 Ohms can be used to refute GERD.The proposed cut-offs move in the correct direction by diminishing the original cut-off,nevertheless they arise from a study of normal subjects where cut-offs were provided by measuring the mean value±2SD and not in symptomatic patients.However,data exist that even symptomatic patients with inconclusive disease or reflux hypersensitivity(RH)show lower MNBI values in comparison to normal subjects or patients with functional heartburn(FH).Moreover,according to the data,MNBI,even among symptomatic patients,is affected by age and body mass index.Also,various studies have proposed different cut-offs by using receiver operating characteristic curve analysis even lower than the one proposed.Finally,no information is given for patients submitted to on-proton pump inhibitors pH-impedance studies even if new and extremely important data now exist.Therefore,even if MNBI is an extremely important tool when trying to approach patients with reflux symptoms and could distinguish conclusive GERD from RH or FH,its values should be interpreted with caution.展开更多
The study on designs for the baseline parameterization has aroused attention in recent years. This paper focuses on two-level regular designs for the baseline parameterization. A general result on the relationship bet...The study on designs for the baseline parameterization has aroused attention in recent years. This paper focuses on two-level regular designs for the baseline parameterization. A general result on the relationship between K-aberration and word length pattern is developed.展开更多
Long-time coherent integration(LTCI)is an effective way for radar maneuvering target detection,but it faces the problem of a large number of search parameters and large amount of calculation.Realizing the simultaneous...Long-time coherent integration(LTCI)is an effective way for radar maneuvering target detection,but it faces the problem of a large number of search parameters and large amount of calculation.Realizing the simultaneous compensation of the range and Doppler migrations in complex clutter back-ground,and at the same time improving the calculation efficiency has become an urgent problem to be solved.The sparse transformation theory is introduced to LTCI in this paper,and a non-parametric searching sparse LTCI(SLTCI)based maneuvering target detection method is proposed.This method performs time reversal(TR)and second-order Keystone transform(SKT)in the range frequency&slow-time data to complete high-order range walk compensation,and achieves the coherent integra-tion of maneuvering target across range and Doppler units via the robust sparse fractional Fourier transform(RSFRFT).It can compensate for the nonlinear range migration caused by high-order motion.S-band and X-band radar data measured in sea clutter background are used to verify the detection performance of the proposed method,which can achieve better detection performance of maneuvering targets with less computational burden compared with several popular integration methods.展开更多
[Objective] This study aimed to avoid and delay the generation of resis- tance in Botrytis cinerea to boscalid. [Method] The sensitivity of Botrytis cinerea to boscalid was tested by the mycelial growth rate method. T...[Objective] This study aimed to avoid and delay the generation of resis- tance in Botrytis cinerea to boscalid. [Method] The sensitivity of Botrytis cinerea to boscalid was tested by the mycelial growth rate method. The distribution of sensitivity variation of B. cinerea to boscalid in different regions was cleared, and the sen- sitivity baseline of B. cinerea from Liaoning Province to boscalid was established. [Result] The ECso values of B. cinerea strains from Liaoning Province ranged from 0.080 0 to 7.787 2μg/ml, and the highest ECho value was 97.34 times higher than the minimum. The average EC50 value (1.973μg/ml) of the 158 strains was treated as the baseline sensitivity of B. cinerea from Liaoning Province to boscalid. [Conclu- sion] It is essential to conduct a risk assessment of drug resistance in B. cinerea to boscalid.展开更多
A frequency-domain equalizer with a mixed-signal adaptive control loop and a novel baseline wander (BLW) canceller are proposed. The equalizer is independent of channel-modeling accuracy,and its control loop is intr...A frequency-domain equalizer with a mixed-signal adaptive control loop and a novel baseline wander (BLW) canceller are proposed. The equalizer is independent of channel-modeling accuracy,and its control loop is intrinsically stable. An AGC function is incorporated into the equalizer without an extra AGC circuit. The proposed BLW canceller uses a peak detector to monitor the BLW and full feedback method to accomplish BLW canceling. High canceling accuracy and robust performance are achieved. The circuits are tested in 0.25μm CMOS technology. Better performance and smaller silicon area are achieved compared with results in the literature.展开更多
When the cycle slips take place in the attitude determination of a moving platform, the precision of the attitude will be impaired badly. A method of cycle slip detection and correction is proposed, which is suitable ...When the cycle slips take place in the attitude determination of a moving platform, the precision of the attitude will be impaired badly. A method of cycle slip detection and correction is proposed, which is suitable to the dynamic measurement using GPS carrier phase: the cycle slips detection is first achieved by triple difference observables, then the cycle slips correction is performed with baseline length constraint. The simulation results show that the proposed method is effective to the dynamic cycle slips problem.展开更多
AIM: To characterize the baseline profiles of patients aged 70 years and above with hepatocellular carcinoma (HCC).METHODS: A series of 127 consecutive patients with HCC were enrolled between 2000 and 2004, and none o...AIM: To characterize the baseline profiles of patients aged 70 years and above with hepatocellular carcinoma (HCC).METHODS: A series of 127 consecutive patients with HCC were enrolled between 2000 and 2004, and none of them had been diagnosed as having HCC previously. Baseline profiles, including parameters of hepatic function such as serum transaminase and prothrombin time [PT (% activity)] were compared between patients aged ≥70 and <70 years.RESULTS: Patients ≥70 years old showed significantly lower levels of aspartate aminotransferase (P = 0.04)and alanine aminotransferase (P = 0.01), and significantly higher PTs (P= 0.04) and platelet counts (P = 0.02).Concomitantly, among ≥70-year-old patients, HCC was more common in non-cirrhotics, whereas among patients <70 years old, HCC was more common in cirrhotics. There was no significant difference between the groups in the number or size of tumors.CONCLUSION: Older HCC patients showed less inflammation and better preservation of hepatic function, indicating that not only cirrhotic patients but also noncirrhotic patients should be considered as a high-risk group among the elderly.展开更多
Urban topsoil is the most frequent interface between human society and natural environment.The accumulation of heavy metals in the urban topsoil has a direct effect on residents'life and health.The geochemical bas...Urban topsoil is the most frequent interface between human society and natural environment.The accumulation of heavy metals in the urban topsoil has a direct effect on residents'life and health.The geochemical baseline of heavy metals is an objective description of the general level of heavy metals in the urban topsoil.Meanwhile,the determination of geochemical baseline is necessary for regional environmental management,especially in coal cities prone to heavy metal pollution.Heavy metal pollution has become an environmental problem in Fuxin City,China for a long time.To establish the geochemical baseline of heavy metals in the topsoil of Fuxin City and to evaluate the ecological risk of the topsoil,we collected 75 topsoil samples(0–20 cm)and analyzed the concentrations of Cu,Ni,Zn,Pb,Cr,Cd,Hg and As through X-ray fluorescence spectrometry,atomic absorption spectrometry and inductively coupled plasma optical emission spectrometry.We determined the geochemical baseline of heavy metals in the topsoil of Fuxin City by using iteration removal,box-whisker plot,cumulative frequency curve and reference metal normalization;evaluated the contamination risk and ecological risk of the topsoil by using the baseline factor index,Nemerow index and Hakanson potential ecological risk index;and identified the source category of heavy metals in the topsoil by using a pedigree clustering heatmap.Results showed that the geochemical baseline values were 42.86,89.34,92.23,60.55,145.21,0.09,0.08 and 4.17 mg/kg for Cu,Ni,Zn,Pb,Cr,Cd,Hg and As,respectively.The results of Nemerow index and Hakanson potential ecological risk index indicated that the urban topsoil in the study area was slightly contaminated and suffering low potential ecological risk.The main contaminated areas dominated in the middle part and northeast part of the study area,especially in the western Haizhou Strip Mine.The result of baseline factor index indicated that Hg and Cd were the major pollution elements.Using a pedigree clustering heatmap,we divided the sources of these heavy metals into three types:type I for Ni and Cr,largely represented the enrichment of heavy metals from natural sources;type II for Cu,Pb,Zn,Cd and As,mainly represented the enrichment of heavy metals from anthropogenic sources;and type III for Hg,represented the form of both natural and anthropogenic inputs.展开更多
Baseline offset in digital strong-motion acceleration record and initial velocity can produce unrealistic results for ground velocity and displacement derived from the acceleration by integration. A new method is prop...Baseline offset in digital strong-motion acceleration record and initial velocity can produce unrealistic results for ground velocity and displacement derived from the acceleration by integration. A new method is proposed for the baseline correction and initial velocity calculation. It is based on linear least-squares fitting of the pre-event portion of velocity derived from the uncorrected acceleration data. Compared with the conventional method,which is based on removing the mean values of the pre-event portions of the acceleration and velocity traces,this method has clearer physical meaning and better stability.展开更多
Long-time coherent integration(LTCI)can remarkably improve the detection ability of radar for moving target.To increase the processing efficiency,this paper proposes a novel LTCI method based on segment time reversing...Long-time coherent integration(LTCI)can remarkably improve the detection ability of radar for moving target.To increase the processing efficiency,this paper proposes a novel LTCI method based on segment time reversing transform(STRT)and chirp z-transform(CZT).In this method,STRT operation is first presented to estimate the Doppler ambiguity factor,and keystone transform(KT)is used to correct the whole range migration(RM).Then,CZT and non-uniform fast Fourier transform(NUFFT)are used to estimate the parameters as well as correct the second and third order Doppler frequency migration(DFM).Compared with the existing methods,the proposed method can achieve RM correction and DFM correction without repetitive operation.The effectiveness of the proposed method is validated by both simulated and real data.展开更多
基金supported by the National MCF Energy R&D Program of China(No.2019YFE03060000)National Natural Science Foundation of China(Nos.12005063,12375215 and 12175034)the Collaborative Innovation Program of Hefei Science Center,CAS(No.2022HSC-CIP008).
文摘The linear and nonlinear simulations are carried out using the gyrokinetic code NLT for the electrostatic instabilities in the core region of a deuterium plasma based on the International Thermonuclear Experimental Reactor(ITER)baseline scenario.The kinetic electron effects on the linear frequency and nonlinear transport are studied by adopting the adiabatic electron model and the fully drift-kinetic electron model in the NLT code,respectively.The linear simulations focus on the dependence of linear frequency on the plasma parameters,such as the ion and electron temperature gradientsκ_(Ti,e)≡R=L_(Ti,e),the density gradientκ_(n)≡R/L_(n)and the ion-electron temperature ratioτ=T_(e)=T_(i).Here,is the major radius,and T_(e)and T_(i)denote the electron and ion temperatures,respectively.L_(A)=-(δ_(r)lnA)^(-1)is the gradient scale length,with denoting the density,the ion and electron temperatures,respectively.In the kinetic electron model,the ion temperature gradient(ITG)instability and the trapped electron mode(TEM)dominate in the small and large k_(θ)region,respectively,wherek_(θ)is the poloidal wavenumber.The TEMdominant region becomes wider by increasing(decreasing)κ_(T_(e))(κ_(T_(i)))or by decreasingκ_(n).For the nominal parameters of the ITER baseline scenario,the maximum growth rate of dominant ITG instability in the kinetic electron model is about three times larger than that in the adiabatic electron model.The normalized linear frequency depends on the value ofτ,rather than the value of T_(e)or T_(i),in both the adiabatic and kinetic electron models.The nonlinear simulation results show that the ion heat diffusivity in the kinetic electron model is quite a lot larger than that in the adiabatic electron model,the radial structure is finer and the time oscillation is more rapid.In addition,the magnitude of the fluctuated potential at the saturated stage peaks in the ITGdominated region,and contributions from the TEM(dominating in the higher k_(θ)region)to the nonlinear transport can be neglected.In the adiabatic electron model,the zonal radial electric field is found to be mainly driven by the turbulent energy flux,and the contribution of turbulent poloidal Reynolds stress is quite small due to the toroidal shielding effect.However,in the kinetic electron model,the turbulent energy flux is not strong enough to drive the zonal radial electric field in the nonlinear saturated stage.The kinetic electron effects on the mechanism of the turbulence-driven zonal radial electric field should be further investigated.
文摘Clinical practice guidelines drive clinical practice and clinicians rely to them when trying to answer their most common questions.One of the most important position papers in the field of gastro-esophageal reflux disease(GERD)is the one produced by the Lyon Consensus.Recently an updated second version has been released.Mean nocturnal baseline impedance(MNBI)was proposed by the first Consensus to act as supportive evidence for GERD diagnosis.Originally a cut-off of 2292 Ohms was proposed,a value revised in the second edition.The updated Consensus recommended that an MNBI<1500 Ohms strongly suggests GERD while a value>2500 Ohms can be used to refute GERD.The proposed cut-offs move in the correct direction by diminishing the original cut-off,nevertheless they arise from a study of normal subjects where cut-offs were provided by measuring the mean value±2SD and not in symptomatic patients.However,data exist that even symptomatic patients with inconclusive disease or reflux hypersensitivity(RH)show lower MNBI values in comparison to normal subjects or patients with functional heartburn(FH).Moreover,according to the data,MNBI,even among symptomatic patients,is affected by age and body mass index.Also,various studies have proposed different cut-offs by using receiver operating characteristic curve analysis even lower than the one proposed.Finally,no information is given for patients submitted to on-proton pump inhibitors pH-impedance studies even if new and extremely important data now exist.Therefore,even if MNBI is an extremely important tool when trying to approach patients with reflux symptoms and could distinguish conclusive GERD from RH or FH,its values should be interpreted with caution.
文摘The study on designs for the baseline parameterization has aroused attention in recent years. This paper focuses on two-level regular designs for the baseline parameterization. A general result on the relationship between K-aberration and word length pattern is developed.
基金supported by the National Natural Science Foundation of China(62222120,61871391,U1933135)Shandong Provincial Natural Science Foundation(ZR2021YQ43).
文摘Long-time coherent integration(LTCI)is an effective way for radar maneuvering target detection,but it faces the problem of a large number of search parameters and large amount of calculation.Realizing the simultaneous compensation of the range and Doppler migrations in complex clutter back-ground,and at the same time improving the calculation efficiency has become an urgent problem to be solved.The sparse transformation theory is introduced to LTCI in this paper,and a non-parametric searching sparse LTCI(SLTCI)based maneuvering target detection method is proposed.This method performs time reversal(TR)and second-order Keystone transform(SKT)in the range frequency&slow-time data to complete high-order range walk compensation,and achieves the coherent integra-tion of maneuvering target across range and Doppler units via the robust sparse fractional Fourier transform(RSFRFT).It can compensate for the nonlinear range migration caused by high-order motion.S-band and X-band radar data measured in sea clutter background are used to verify the detection performance of the proposed method,which can achieve better detection performance of maneuvering targets with less computational burden compared with several popular integration methods.
基金Supported by Special Fund for Agro-scientific Research in the Public Interest of China(201303025)~~
文摘[Objective] This study aimed to avoid and delay the generation of resis- tance in Botrytis cinerea to boscalid. [Method] The sensitivity of Botrytis cinerea to boscalid was tested by the mycelial growth rate method. The distribution of sensitivity variation of B. cinerea to boscalid in different regions was cleared, and the sen- sitivity baseline of B. cinerea from Liaoning Province to boscalid was established. [Result] The ECso values of B. cinerea strains from Liaoning Province ranged from 0.080 0 to 7.787 2μg/ml, and the highest ECho value was 97.34 times higher than the minimum. The average EC50 value (1.973μg/ml) of the 158 strains was treated as the baseline sensitivity of B. cinerea from Liaoning Province to boscalid. [Conclu- sion] It is essential to conduct a risk assessment of drug resistance in B. cinerea to boscalid.
文摘A frequency-domain equalizer with a mixed-signal adaptive control loop and a novel baseline wander (BLW) canceller are proposed. The equalizer is independent of channel-modeling accuracy,and its control loop is intrinsically stable. An AGC function is incorporated into the equalizer without an extra AGC circuit. The proposed BLW canceller uses a peak detector to monitor the BLW and full feedback method to accomplish BLW canceling. High canceling accuracy and robust performance are achieved. The circuits are tested in 0.25μm CMOS technology. Better performance and smaller silicon area are achieved compared with results in the literature.
文摘When the cycle slips take place in the attitude determination of a moving platform, the precision of the attitude will be impaired badly. A method of cycle slip detection and correction is proposed, which is suitable to the dynamic measurement using GPS carrier phase: the cycle slips detection is first achieved by triple difference observables, then the cycle slips correction is performed with baseline length constraint. The simulation results show that the proposed method is effective to the dynamic cycle slips problem.
文摘AIM: To characterize the baseline profiles of patients aged 70 years and above with hepatocellular carcinoma (HCC).METHODS: A series of 127 consecutive patients with HCC were enrolled between 2000 and 2004, and none of them had been diagnosed as having HCC previously. Baseline profiles, including parameters of hepatic function such as serum transaminase and prothrombin time [PT (% activity)] were compared between patients aged ≥70 and <70 years.RESULTS: Patients ≥70 years old showed significantly lower levels of aspartate aminotransferase (P = 0.04)and alanine aminotransferase (P = 0.01), and significantly higher PTs (P= 0.04) and platelet counts (P = 0.02).Concomitantly, among ≥70-year-old patients, HCC was more common in non-cirrhotics, whereas among patients <70 years old, HCC was more common in cirrhotics. There was no significant difference between the groups in the number or size of tumors.CONCLUSION: Older HCC patients showed less inflammation and better preservation of hepatic function, indicating that not only cirrhotic patients but also noncirrhotic patients should be considered as a high-risk group among the elderly.
基金the National Natural Science Foundation of China(41271064)the Foundation of Liaoning Educational Committee,China(L201783640)the PhD Research Startup Foundation of Liaoning University,China(BS2018L014)。
文摘Urban topsoil is the most frequent interface between human society and natural environment.The accumulation of heavy metals in the urban topsoil has a direct effect on residents'life and health.The geochemical baseline of heavy metals is an objective description of the general level of heavy metals in the urban topsoil.Meanwhile,the determination of geochemical baseline is necessary for regional environmental management,especially in coal cities prone to heavy metal pollution.Heavy metal pollution has become an environmental problem in Fuxin City,China for a long time.To establish the geochemical baseline of heavy metals in the topsoil of Fuxin City and to evaluate the ecological risk of the topsoil,we collected 75 topsoil samples(0–20 cm)and analyzed the concentrations of Cu,Ni,Zn,Pb,Cr,Cd,Hg and As through X-ray fluorescence spectrometry,atomic absorption spectrometry and inductively coupled plasma optical emission spectrometry.We determined the geochemical baseline of heavy metals in the topsoil of Fuxin City by using iteration removal,box-whisker plot,cumulative frequency curve and reference metal normalization;evaluated the contamination risk and ecological risk of the topsoil by using the baseline factor index,Nemerow index and Hakanson potential ecological risk index;and identified the source category of heavy metals in the topsoil by using a pedigree clustering heatmap.Results showed that the geochemical baseline values were 42.86,89.34,92.23,60.55,145.21,0.09,0.08 and 4.17 mg/kg for Cu,Ni,Zn,Pb,Cr,Cd,Hg and As,respectively.The results of Nemerow index and Hakanson potential ecological risk index indicated that the urban topsoil in the study area was slightly contaminated and suffering low potential ecological risk.The main contaminated areas dominated in the middle part and northeast part of the study area,especially in the western Haizhou Strip Mine.The result of baseline factor index indicated that Hg and Cd were the major pollution elements.Using a pedigree clustering heatmap,we divided the sources of these heavy metals into three types:type I for Ni and Cr,largely represented the enrichment of heavy metals from natural sources;type II for Cu,Pb,Zn,Cd and As,mainly represented the enrichment of heavy metals from anthropogenic sources;and type III for Hg,represented the form of both natural and anthropogenic inputs.
基金supported by the National Natural Science Foundation of China( 41004020)the Director Foundation of Institute of Seismology,CEA(IS200926044)
文摘Baseline offset in digital strong-motion acceleration record and initial velocity can produce unrealistic results for ground velocity and displacement derived from the acceleration by integration. A new method is proposed for the baseline correction and initial velocity calculation. It is based on linear least-squares fitting of the pre-event portion of velocity derived from the uncorrected acceleration data. Compared with the conventional method,which is based on removing the mean values of the pre-event portions of the acceleration and velocity traces,this method has clearer physical meaning and better stability.
基金the National Natural Foundation of China(Nos.61771046,61731023 and 62171029).
文摘Long-time coherent integration(LTCI)can remarkably improve the detection ability of radar for moving target.To increase the processing efficiency,this paper proposes a novel LTCI method based on segment time reversing transform(STRT)and chirp z-transform(CZT).In this method,STRT operation is first presented to estimate the Doppler ambiguity factor,and keystone transform(KT)is used to correct the whole range migration(RM).Then,CZT and non-uniform fast Fourier transform(NUFFT)are used to estimate the parameters as well as correct the second and third order Doppler frequency migration(DFM).Compared with the existing methods,the proposed method can achieve RM correction and DFM correction without repetitive operation.The effectiveness of the proposed method is validated by both simulated and real data.