Long-term trends in the abundance and breeding performance in Adélie penguins:the Argentine Ecosystem Monitoring Program

In this work,we report long-term trends in the abundance and breeding performance of Adélie penguins(Pygoscelis adeliae)nesting in three Antarctic colonies(i.e.,at Martin Point,South Orkneys Islands;Stranger Point/Cabo Funes,South Shetland Islands;and Esperanza/Hope Bay in the Antarctic Peninsula)from 1995/96 to 2022/23.Using yearly count data of breeding groups selected,we observed a decline in the number of breeding pairs and chicks in crèche at all colonies studied.However,the magnitude of change was higher at Stranger Point than that in the remaining colonies.Moreover,the index of breeding success,which was calculated as the ratio of chicks in crèche to breeding pairs,exhibited no apparent trend throughout the study period.However,it displayed greater variability at Martin Point compared to the other two colonies under investigation.Although the number of chicks in crèche of Adélie penguins showed a declining pattern,the average breeding performance was similar to that reported in gentoo penguin colonies,specifically,those undergoing a population increase(even in sympatric colonies facing similar local conditions).Consequently,it is plausible to assume a reduction of the over-winter survival as a likely cause of the declining trend observed,at least in the Stranger Point and Esperanza colonies.However,we cannot rule out local effects during the breeding season affecting the Adélie population of Martin Point.

Long-Term Trends in Pre-Summer Daytime and Nocturnal Extreme Hourly Rainfall in a Coastal City of South China

The long-term trends in the occurrence frequency of pre-summer daytime and nocturnal extreme hourly rainfall(EXHR) during 1988-2018 in Hong Kong and their spatial distributions are examined and analyzed. Despite a significant increasing trend observed in the occurrence frequency of pre-summer EXHRs during the investigated period,the increase in daytime and nocturnal EXHRs show distinct spatial patterns. Nocturnal EXHRs show uniform increasing trends over the entire Hong Kong. However, the increase in daytime EXHRs is concentrated over the northern or eastern areas of Hong Kong, indicating a downstream shift of pre-summer EXHRs in Hong Kong with regard to the prevailing southwesterly monsoonal flows in south China. The clustering of weather types associated with daytime and nocturnal EXHRs further reveals that the increase in EXHRs over Hong Kong are mainly contributed by the increase of the events associated with southwesterly monsoonal flows with relatively high speeds. During the past few decades, the southwesterly monsoonal flows at coastal south China have undergone a substantial weakening due to the increased surface roughness induced by the urbanization over the Guangdong-Hong Kong-Macao Greater Bay Area since 1990s,leading to enhanced low-level convergence and thus significant increase in EXHRs at coastal south China. Meanwhile,daytime sea-wind circulation at coastal south China is markedly enhanced during the investigated period, which is the main reason for the northward shift of daytime EXHRs in Hong Kong. In addition, the blocked southwesterly monsoonal flows at coastal south China are detoured eastward, leading to stronger convergence and increase in EXHRs at eastern coast of Hong Kong, especially during daytime, when the easterly sea winds prevail at the region.

The long-term trend of the sea surface wind speed and the wave height (wind wave, swell, mixed wave) in global ocean during the last 44 a

Utilizing the 45 a European Centre for Medium-Range Weather Forecasts （ECMWF） reanalysis wave da- ta （ERA-40）, the long-term trend of the sea surface wind speed and （wind wave, swell, mixed wave） wave height in the global ocean at grid point 1.5°× 1.5° during the last 44 a is analyzed. It is discovered that a ma- jority of global ocean swell wave height exhibits a significant linear increasing trend （2-8 cm/decade）, the distribution of annual linear trend of the significant wave height （SWH） has good consistency with that of the swell wave height. The sea surface wind speed shows an annually linear increasing trend mainly con- centrated in the most waters of Southern Hemisphere westerlies, high latitude of the North Pacific, Indian Ocean north of 30°S, the waters near the western equatorial Pacific and low latitudes of the Atlantic waters, and the annually linear decreasing mainly in central and eastern equator of the Pacific, Juan. Fernandez Archipelago, the waters near South Georgia Island in the Atlantic waters. The linear variational distribution characteristic of the wind wave height is similar to that of the sea surface wind speed. Another find is that the swell is dominant in the mixed wave, the swell index in the central ocean is generally greater than that in the offshore, and the swell index in the eastern ocean coast is greater than that in the western ocean inshore, and in year-round hemisphere westerlies the swell index is relatively low.

Long-Term Trends in Extreme Temperatures in Hong Kong and Southern China

The observed long-term trends in extreme temperatures in Hong Kong were studied based on the meteorological data recorded at the Hong Kong Observatory Headquarters from 1885-2008. Results show that, over the past 124 years, the extreme daily minimum and maximum temperatures, as well as the length of the warm spell in Hong Kong, exhibit statistically significant long-term rising trends, while the length of the cold spell shows a statistically significant decreasing trend. The time-dependent return period analysis also indicated that the return period for daily minimum temperature at 4°C or lower lengthened considerably from 6 years in 1900 to over 150 years in 2000, while the return periods for daily maximum temperature reaching 35°C or above shortened drastically from 32 years in 1900 to 4.5 years in 2000. Past trends in extreme temperatures from selected weather stations in southern China from 1951-2004 were also assessed. Over 70% of the stations studied yielded a statistically significant rising trend in extreme daily minimum temperature, while the trend for extreme maximum temperatures was found to vary, with no significant trend established for the majority of stations.

Long-Term Trends in Photosynthetically Active Radiation in Beijing

A long-term dataset of photosynthetically active radiation （Qp） is reconstructed from a broadband global solar radiation （Rs） dataset through an all-weather reconstruction model. This method is based on four years＇ worth of data collected in Beijing. Observation data of Rs and Qp from 2005-2008 are used to investigate the temporal variability of Qp and its dependence on the clearness index and solar zenith angle. A simple and effcient all-weather empirically derived reconstruction model is proposed to reconstruct Qp from Rs. This reconstruction method is found to estimate instantaneous Qp with high accuracy. The annual mean of the daily values of Qp during the period 1958-2005 period is 25.06 mol m-2 d-1. The magnitude of the long-term trend for the annual averaged Qp is presented （-0.19 mol m-2 yr-1 from 1958-1997 and -0.12 mol m-2 yr-1 from 1958-2005）. The trend in Qp exhibits sharp decreases in the spring and summer and more gentle decreases in the autumn and winter.

Long-Term Trends in the Probability of Different Grades of Haze Days in China from 1960 to 2013

The number of haze days and daily visibility data for 543 stations in China were used to define the probabilities of four grades of haze days:slight haze(SLH)days;light haze(LIH)days;moderate haze(MOH)days;and severe haze(SEH)days.The change trends of the four grades of haze were investigated and the following results were obtained.The highest probability was obtained for SLH days(95.138%),which showed a decreasing trend over the last54 years with the fastest rate of decrease of-0.903%·(10 years)-1 and a trend coefficient of-0.699,passing the 99.9%confidence level.The probabilities of LIH and MOH days increased steadily,whereas the probability of SEH days showed a slight downward trend during that period.The increasing probability of SLH days was mainly distributed to the east of 105°E and the south of 42°N and the highest value of the trend coefficient was located in the Pearl River Delta and Yangtze River Delta regions.The increasing probability of LIH days was mainly distributed in eastern China and the southeastern coastal region.The probabilities of MOH and SEH days was similar to the probability of LIH days.An analysis of the four grades of haze days in cities with different sizes suggested that the probability of SLH days in large cities and medium cities clearly decreased during the last 54 years.However,the probabilities of LIH days was<10%and increased steadily.The probability of MOH days showed a clear interdecadal fluctuation and the probability of SEH days showed a weak upward trend.The probability of SLH days in small cities within 0.8°of large or medium cities decreased steadily,but the probability of LIH and MOH days clearly increased,which might be attributed to the impact of large and medium cities.The probability of SLH days in small cities>1.5°from a large or medium city showed an increasing trend and reached 100%after 1990;the probability of the other three grades was small and decreased significantly.

Long-term trend analysis of wave characteristics in the Bohai Sea based on interpolated ERA5 wave reanalysis from 1950 to 2020

Reasonably understanding of the long-term wave characteristics is very crucial for the ocean engineering.A feedforward neural network is operated for interpolating ERA5 wave reanalysis in this study,which embodies a detailed record from 1950 onwards.The spatiotemporal variability of wave parameters in the Bohai Sea,especially the significant wave height(SWH),is presented in terms of combined wave,wind wave and swell by employing the 71 years(1950–2020)of interpolated ERA5 reanalysis.Annual mean SWH decreases at−0.12 cm/a estimated by Theil-Sen estimator and 95th percentile SWH reflecting serve sea states decreases at−0.20 cm/a.Inter-seasonal analysis shows SWH of wind wave has steeper decreasing trend with higher slopes than that of swell,especially in summer and winter,showing the major decrease may attribute to the weakening of monsoon.The inner Bohai Sea reveals a general decreasing trend while the intersection connecting with the Yellow Sea has the lower significance derived by Mann-Kendall test.Meanwhile,95th percentile SWH decreases at a higher rate while with a lower significance in comparison with the mean state.The frequencies of mean wave directions in sub-sector are statistically calculated to find the seasonal prevailing directions.Generally,the dominant directions in summer and winter are south and north.A similar variation concerning to SWH,the trend of the mean wave period is provided,which also shows a decrease for decades.

Estimation and Long-term Trend Analysis of Surface Solar Radiation in Antarctica: A Case Study of Zhongshan Station

Long-term,ground-based daily global solar radiation (DGSR) at Zhongshan Station in Antarctica can quantitatively reveal the basic characteristics of Earth’s surface radiation balance and validate satellite data for the Antarctic region.The fixed station was established in 1989,and conventional radiation observations started much later in 2008.In this study,a random forest (RF) model for estimating DGSR is developed using ground meteorological observation data,and a highprecision,long-term DGSR dataset is constructed.Then,the trend of DGSR from 1990 to 2019 at Zhongshan Station,Antarctica is analyzed.The RF model,which performs better than other models,shows a desirable performance of DGSR hindcast estimation with an R^2 of 0.984,root-mean-square error of 1.377 MJ m^(-2),and mean absolute error of 0.828 MJ m^(-2).The trend of DGSR annual anomalies increases during 1990–2004 and then begins to decrease after 2004.Note that the maximum value of annual anomalies occurs during approximately 2004/05 and is mainly related to the days with precipitation (especially those related to good weather during the polar day period) at this station.In addition to clouds and water vapor,bad weather conditions (such as snowfall,which can result in low visibility and then decreased sunshine duration and solar radiation) are the other major factors affecting solar radiation at this station.The high-precision,longterm estimated DGSR dataset enables further study and understanding of the role of Antarctica in global climate change and the interactions between snow,ice,and atmosphere.

foF2 Long-Term Trend at a Station Located near the Crest of the Equatorial Ionization Anomaly

Critical frequency foF2 long-term trends at Dakar station (14.4°N, 342.74°E) located near the crest of the equatorial ionization anomaly EIA, are analysed taking into account geomagnetic activity, increasing greenhouse gases concentration and Earth’s magnetic field secular variation. After filtering solar activity effect using F10.7 as a solar activity proxy, we determined the relative residual trends slopes α values for three different levels of geomagnetic activity. For example, at 1200 LT, the value of α goes from -0.27%/year for very magnetically quiet days to -0.19%/year for magnetically quiet days and to -0.13%/year for all days. It appears from the slopes α obtained, that they increase with the level of geomagnetic activity and their negative values are qualitatively consistent with the expected decreasing trend due to the increase in greenhouse gases concentration but are greater than 0.003%/year which would result from a 20% increase in CO2 emissions which actually took place during the analysis period. Regarding Earth’s magnetic field magnitude, B secular variation and the dip equator secular movement, Dakar station is located near the crest of the equatorial ionization anomaly, Earth’s magnetic field magnitude, B decreases there and the trough approaches the position of Dakar during the period of analysis. These two phenomena induce a decrease in foF2 which is in agreement with the decreasing trend observed at this station.

Long-Term Trends and Its Best Functional Form Estimation of Yearly Maximum and Minimum Temperatures at Cotonou City by Improved Complete Ensemble Empirical Mode Decomposition with Adaptive Noise Method

The understanding of the long-term trend in climatic variables is necessary for the climate change impacts studies and for modeling several processes in environmental engineering. However, for climatic variables, long-term trend is usually unknown whether there is a trend component and, if so, the functional form of this trend is also unknown. In this context, a conventional strategy consists to assume randomly the shape of the local trends in the time series. For example, the polynomial forms with random order are arbitrarily chosen as the shape of the trend without any previous justification. This study aims to 1) estimate the real long-term nonlinear trend and the changing rate of the yearly high temperature among the daily minimum (YHTaDMinT) and maximum temperatures (YHTaDMaxT) observed at Cotonou city, 2) find out for these real trend and trend increment, the best polynomial trend model among four trend models (linear, quadratic, third-order and fourth-order polynomial function). For both time series, the results show that YHTaDMinT and YHTaDMaxT time series are characterized by nonlinear and monotonically increasing trend. The trend increments present different phases in their nonmonotone variations. Among the four trend estimations models, the trend obtained by third-order and fourth-order polynomial functions exhibits a close pattern with the real long-term nonlinear trend given by the Improved Complete Ensemble Empirical Mode Decomposition with Adaptive Noise (ICEEMDAN). But, the fourth-order polynomial function is optimal, therefore, it can be used as the functional form of trend. In the trend increment case, for the YHTaDMaxT time series, the fourth-order fit is systematically the best among the four proposed trend models. Whereas for the YHTaDMinT time series, the third-order and fourth-order polynomial functions present the same performance. They can both be used as the functional form of trend increments. Overall, the fourth-order polynomial function presents a good performance in terms of trend and trend increments estimation.

CLIMATE CHANGE:LONG-TERM TRENDS AND SHORT-TERM OSCILLATIONS

Identifying the Northern Hemisphere （NH） temperature reconstruction and instrumental data for the past 1000 years shows that climate change in the last millennium includes long-term trends and varioas oscillations. Two long-term trends and the quasi-70-year oscillation were detected in the global temperature series tbr the last 140 years and the NH millennium series. One important feature was emphasized that temperature decreases slowly but it increases rapidly based on the analysis of different series. Benefits can be obtained of climate change from understanding various long-term trends and oscillations. Millennial temperature proxies from the natural climate system and time series of nonlinear model system are used in understanding the natural climate change and recognizing potential benefits by using the method of wavelet transform analysis. The results from numerical modeling show that major oscillations contained in numerical solutions on the interdecadal timescale are consistent with that of natural proxies. It seems that these oscillations in the climate change are not directly linked with the solar radiation as an external tbrcing. This investigation may conclude that the climate variability at the interdecadal timescale strongly depends on the internal nonlinear effects in the climate system.

Long-Term Trends in Near-Surface Wind Speed over the Southern Hemisphere: A Preliminary Analysis

Many studies that discuss observed trends in wind speed focus primarily on regions of the Northern Hemisphere, so there is little research directed to the Southern Hemisphere. This paper pre- sents a preliminary investigation of possible statistically significant trends in wind speed over the Southern Hemisphere, with a detailing on the South American continent, between 1961 and 2008. Thus, data from the 20th Century Reanalysis V2 were examined with statistical tests of Mann- Kendall and Sen’s Bend in order to establish the significance and the magnitude of detected trends. The previous results indicate statistically significant trends of increase in average wind speedover the equatorial region of the planet, as well as in the eastern sector of the South Pacific and South Atlantic Oceans. In South America, the most significant trends of decrease in wind speed were noted in some areas of the southern sector of the continent, even as in the adjacent Atlantic Ocean to Argentina. Further studies should be performed to physically support the occurrence of these trends in wind speed. In addition, other observed and reanalysis data sets should be explored to update and corroborate these primary analyzes.

Long-Term Trends of Carbon Monoxide Total Columnar Amount in Urban Areas and Background Regions:Ground-and Satellite-based Spectroscopic Measurements

A comparative study was carried out to explore carbon monoxide total columnar amount（CO TC） in background and polluted atmosphere, including the stations of ZSS（Zvenigorod）, ZOTTO（Central Siberia）, Peterhof, Beijing, and Moscow,during 1998–2014, on the basis of ground-and satellite-based spectroscopic measurements. Interannual variations of CO TC in different regions of Eurasia were obtained from ground-based spectroscopic observations, combined with satellite data from the sensors MOPITT（2001–14）, AIRS（2003–14）, and IASI Met Op-A（2010–13）. A decreasing trend in CO TC（1998–2014） was found at the urban site of Beijing, where CO TC decreased by 1.14% ± 0.87% yr^（-1）. Meanwhile, at the Moscow site, CO TC decreased remarkably by 3.73% ± 0.39% yr^（-1）. In the background regions（ZSS, ZOTTO, Peterhof）, the reduction was 0.9%–1.7% yr^（-1） during the same period. Based on the AIRSv6 satellite data for the period 2003–14, a slight decrease（0.4%–0.6% yr^（-1）） of CO TC was detected over the midlatitudes of Eurasia, while a reduction of 0.9%–1.2% yr^（-1） was found in Southeast Asia. The degree of correlation between the CO TC derived from satellite products（MOPITTv6 Joint, AIRSv6 and IASI Met Op-A） and ground-based measurements was calculated, revealing significant correlation in unpolluted regions.While in polluted areas, IASI Met Op-A and AIRSv6 data underestimated CO TC by a factor of 1.5–2.8. On average, the correlation coefficient between ground-and satellite-based data increased significantly for cases with PBL heights greater than 500 m.

Long-term ocean temperature trend and marine heatwaves

Marine heatwaves(MHWs)can cause irreversible damage to marine ecosystems and livelihoods.Appropriate MHW characterization remains difficult,because the choice of a sea surface temperature(SST)temporal baseline strongly influences MHW identification.Following a recent work suggesting that there should be a communicating baseline for long-term ocean temperature trends(LTT)and MHWs,we provided an effective and quantitative solution to calculate LTT and MHWs simultaneously by using the ensemble empirical mode decomposition(EEMD)method.The long-term nonlinear trend of SST obtained by EEMD shows superiority over the traditional linear trend in that the data extension does not alter prior results.The MHWs identified from the detrended SST data exhibited low sensitivity to the baseline choice,demonstrating the robustness of our method.We also derived the total heat exposure(THE)by combining LTT and MHWs.The THE was sensitive to the fixed-period baseline choice,with a response to increasing SST that depended on the onset time of a perpetual MHW state(identified MHW days equal to the year length).Subtropical areas,the Indian Ocean,and part of the Southern Ocean were most sensitive to the long-term global warming trend.

Long-term variation of Arctic Sudden Stratospheric Warmings(SSW)and potential causes

Utilizing the European Centre for Medium-Range Weather Forecast(ECMWF)Reanalysis v5(ERA5),for the first time,we have confirmed close links among Sudden Stratospheric Warmings(SSWs)in the Northern Hemisphere(NH),the polar vortices,and stratospheric Planetary Waves(PWs)by analyzing and comparing their trends.Interestingly,within overall increasing trends,the duration and strength of SSWs exhibit increasing and decreasing trends before and after the winter of 2002,respectively.To reveal possible physical mechanisms driving these trends,we analyzed the long-term trends of the winter(from December to February)polar vortices and of stratospheric PWs with zonal wave number 1.Notably,our results show that in all three time periods(the entire period of 41winters,1980 to 2020,and the two subperiods—1980-2002 and 2002-2020)enhancing SSWs were always accompanied by weakening winter polar vortices and strengthening polar PWs like Stationary Planetary Waves(SPWs)and 16-day waves,and vice versa.This is the first proof,based on ERA5 long-term trend data,that weakening polar vortices and enhancing stratospheric PWs(especially SPWs)could cause an increase in SSWs.

Coupling and Long-term Change Characteristics of Forest Carbon Sink and Forestry Economic Development in China

[Objectives]To analyze the changes in of forest carbon sink and forestry economic development,provide reference for relevant management decisions,ecological governance and resource and environment management,and promote the development of green low-carbon economy in China.[Methods]Based on the data of six forest resource inventories from 1989 to 2018 and related studies,the comprehensive evaluation model of forest carbon sink and forestry economic development,the coupling degree model of forest carbon sink and forestry economic development,and the coupling coordination degree model of forest carbon sink and forestry economic development were adopted.The coupling degree of forest carbon sink and forestry economic development from 1992 to 2018 was analyzed.Stepwise regression and ARIMA model were used to analyze the influencing factors and lagging characteristics of forest carbon sink.The coupling degree between forest carbon sink and forestry economic development in China from 2019 to 2030 was predicted by autoregression and ADF test.The coupling between forest carbon sink and forestry economic development in China and its long-term change characteristics were also discussed in this study.[Results](i)The investment of ecological construction and protection,the actual investment of forestry key ecological projects,GDP and the import of forest products had a significant impact on forest resources carbon stock.The total output value of forestry industry,the actually completed investment of forestry key ecological projects and the export volume of forest products had a significant impact on the forest carbon sink,and the actually completed investment of forestry key ecological projects has the greatest impact on the two.(ii)The impact of actually completed investment of forestry key ecological projects had a lag of 2 years on the forest resources carbon stock and a lag of 1 year on the forest carbon sink.When investing in forest carbon sink,it is necessary to make a good plan in advance,and do a good job in forest resources management and time optimization.(iii)From 1992 to 2018,the coupling degree of forest resources carbon stock,forest carbon sink and long-term development of forestry economy in China was gradually increasing.Although there were some fluctuations in the middle time,the coupling degree of forest resources carbon stock and the long-term development of forestry economy increased by 9.24%annually,and the degree of coupling coordination increased from"serious imbalance"in 1992 to"high-quality coordination"in 2018.From 1993 to 2018,the coupling degree of forest carbon sink and long-term development of forestry economy increased by 9.63%annually,slightly faster than the coupling coordination degree of forest resources carbon stock and long-term development of forestry economy.The coordination level also rose from level 2 in 1993 to level 10 in 2018.(iv)The prediction shows that the coupling coordination degree of forest resources carbon stock,forest carbon sink and the long-term development of forestry economy would increase from 2019 to 2030.The coupling coordination degree(D)values of both were close to 1,the coordination level was also 10 for a long time,and the degree of coupling coordination was also maintained at the"high-quality coordination"level for a long time.[Conclusions]Forest has multiple benefits of society,economy and ecology,and forest carbon sink is only a benefit output.The long-term coupling analysis of forest carbon sink and forestry economic development is a key point to multiple benefit analysis.The analysis shows that the spillover effect and co-evolution effect of forest carbon sink in China are significant.From 1992 to 2018,the coupling coordination degree of forest carbon sink and forestry economic development was gradually rising.The prediction analysis also indicate that the coupling coordination degree between the forest carbon sink and the long-term development of forestry economy will remain at the level of"high-quality coordination"for a long time from 2019 to 2030.Therefore,improving the level of forest management and maintaining the current trend of increasing forest resources are the key to achieving the goal of carbon peaking and carbon neutrality in China.

Analysis of Temperature Trends and Variations in the Arabian Peninsula’s Upper Atmosphere

In this study, the trends of upper-air temperatures are analysed by utilising radiosonde observations for the barometric levels at 700, 500, 300, 200, 150, 100 and 50 hPa from five meteorological stations within the Arabian Peninsula from January 1986 to August 2015. The mean monthly variations of the temperatures at these levels are characterised and established. The magnitudes of the annual trends of the mean temperatures for each site for the selected barometric levels are studied and statistically tested using Mann-Kendall rank statistics at different significance levels. The temperature trends at different pressure levels show that the upper troposphere and lower stratosphere are warming, while the middle troposphere is cooling which is consistent with the findings of other studies. The variations in upper air temperature observed in this study can be attributed to a range of factors, including increasing greenhouse gas concentrations, changes in atmospheric circulation patterns, variations in solar activity, aerosols and volcanic eruptions, and land use and land cover change.

Long-Term Rainfall Trends in South West Asia—Saudi Arabia

In this study, rainfall data from 19 stations in Saudi Arabia (SA) for the period 1985-2019 was utilized to investigate interannual, monthly, and seasonal rainfall variations and trends. The magnitudes of these trends were characterized and tested using Mann-Kendall (MK) rank statistics at different significance levels. During this study period, the mean rainfall in SA showed a slight and significant decreasing trend by about 2 mm/35 years. Investigation of seasonal trends of rainfall revealed that Winter and Spring rainfall decreased significantly by 2.7 mm/35 years and 5.4 mm/35 years respectively. Three months showed very slight significant decreasing trends of rainfall. These were the months of February, March and April. Mann-Kendall analyses were carried out to investigate the annual trends of rainfall during three sub-periods, i.e., 1985-1996, 1997-2008, and 2009-2019. The results revealed that while rainfall increased by 5.3 mm/12 years and 7.8 mm/11 years for the first and the third periods respectively, it decreased by about 11 mm/12 years during the second period. While trends of rainfall in Saudi Arabia are affected by large scale circulations and local factors, the effect of extraterrestrial factors, such as solar activity and its consequent effects on the climate may, additionally, play a potential role in affecting the pattern of rainfall in Saudi Arabia.

从Google Trends看“一带一路”倡议的国际反响

[目的/意义]2013年中国提出“一带一路”倡议,这对推动我国继续繁荣发展并为全球提供中国治理体系方案等具有重大意义。[方法/过程]利用Google Trends,分析中国“一带一路”倡议的国际反响及其潜在阻碍因子。[结果/结论]“一带一路”倡议受到国际上绝大多数国家民众的支持和关注;个别国家为了压制中国的国际影响力,通过“债务陷阱外交”“珍珠链战略”以及环境问题等方面抹黑“一带一路”,行动上提出“重建更好世界”等企图替代中国的“一带一路”倡议。得益于“一带一路”倡议投资没有附加条件以及G7国家内部自身问题,“一带一路”倡议仍然获得了广大第三世界国家的支持,并将继续是推动世界经济发展的重要力量。

Clinical manifestations,diagnosis and long-term prognosis of adult autoimmune enteropathy:Experience from Peking Union Medical College Hospital

BACKGROUND Autoimmune enteropathy(AIE)is a rare disease whose diagnosis and long-term prognosis remain challenging,especially for adult AIE patients.AIM To improve overall understanding of this disease’s diagnosis and prognosis.METHODS We retrospectively analyzed the clinical,endoscopic and histopathological characteristics and prognoses of 16 adult AIE patients in our tertiary medical center between 2011 and 2023,whose diagnosis was based on the 2007 diagnostic criteria.RESULTS Diarrhea in AIE patients was characterized by secretory diarrhea.The common endoscopic manifestations were edema,villous blunting and mucosal hyperemia in the duodenum and ileum.Villous blunting(100%),deep crypt lymphocytic infiltration(67%),apoptotic bodies(50%),and mild intraepithelial lymphocytosis(69%)were observed in the duodenal biopsies.Moreover,there were other remarkable abnormalities,including reduced or absent goblet cells(duodenum 94%,ileum 62%),reduced or absent Paneth cells(duodenum 94%,ileum 69%)and neutrophil infiltration(duodenum 100%,ileum 69%).Our patients also fulfilled the 2018 diagnostic criteria but did not match the 2022 diagnostic criteria due to undetectable anti-enterocyte antibodies.All patients received glucocorticoid therapy as the initial medication,of which 14/16 patients achieved a clinical response in 5(IQR:3-20)days.Immunosuppressants were administered to 9 patients with indications of steroid dependence(6/9),steroid refractory status(2/9),or intensified maintenance medication(1/9).During the median of 20.5 months of followup,2 patients died from multiple organ failure,and 1 was diagnosed with non-Hodgkin’s lymphoma.The cumulative relapse-free survival rates were 62.5%,55.6%and 37.0%at 6 months,12 months and 48 months,respectively.CONCLUSION Certain histopathological findings,including a decrease or disappearance of goblet and Paneth cells in intestinal biopsies,might be potential diagnostic criteria for adult AIE.The long-term prognosis is still unsatisfactory despite corticosteroid and immunosuppressant medications,which highlights the need for early diagnosis and novel medications.