Congenital unilateral lower lip palsy(CULLP),or congenital hypoplasia of the depressor anguli oris muscle,also known as asymmetric crying facies,is a rare condition that results in asymmetry of the lower lip during sm...Congenital unilateral lower lip palsy(CULLP),or congenital hypoplasia of the depressor anguli oris muscle,also known as asymmetric crying facies,is a rare condition that results in asymmetry of the lower lip during smiling,laughing,and crying.Although the etiology is unknown,weakness of the depressor labii inferioris(DLI)muscle is implicated as a contributing factor.Currently,no well-established treatment options are available.This case report describes an 18-year-old male patient diagnosed with CULLP.Physical examination revealed a symmetric face at rest,but asymmetry when smiling and opening the mouth.Following the administration of lidocaine into the affected DLI muscle,the patient’s smile and lower lip symmetry were immediately restored without any adverse effects.Subsequently,administration of botulinum toxin for neuromodulation of the DLI muscle led to a significant improvement in symmetry and oral function within 2 weeks,which was sustained at 1 month and 3 months post-treatment.No adverse effects were reported,and both patients and families expressed high satisfaction with the outcomes.This case highlights the potential use of neuromodulation as a minimally invasive and effective treatment for CULLP.展开更多
Introduction: Squamous cell carcinomas of the lip essentially pose a therapeutic management problem. In the West, their treatment is done under general anesthesia and follows the classic rules of oncology. In our cont...Introduction: Squamous cell carcinomas of the lip essentially pose a therapeutic management problem. In the West, their treatment is done under general anesthesia and follows the classic rules of oncology. In our context of exercise, we sometimes have a different attitude dictated by various constraints. Observation: 55-year-old patient with no notable history, seen in consultation for a very large ulcerative-budding lesion on the right 2/3 of the lower lip with mucocutaneous involvement without lymph node findings found on examination. Faced with this suspicious lesion and the patient’s financial difficulties, we decided to operate under local anesthesia to remove this tumor. The oncological excision was followed by immediate plasty using a Camille-Bernard flap with a good immediate aesthetic and functional result and postoperative day 7. The patient was unable to take his surgical specimen to anatomy-pathology and was lost to follow-up due to lack of financial resources. On anatomo-pathological analysis of the surgical specimen, the margins were healthy with confirmation of squamous cell carcinoma (anapathological reading made for scientific interest). Discussion: The particular mentality of certain patients and their difficult financial conditions push us to have an unconventional therapeutic attitude in oncology, but which nevertheless makes it possible to resolve certain problems that we often face. Local anesthesia is possible and realistic in cases like ours and the results can be acceptable and life-saving.展开更多
BACKGROUND This paper introduces a case of recurrent keratoacanthoma(KA).KA is a selfhealing disease.Recurrence after surgical resection is rare.In this case,the local application of retinoic acid ointment after the s...BACKGROUND This paper introduces a case of recurrent keratoacanthoma(KA).KA is a selfhealing disease.Recurrence after surgical resection is rare.In this case,the local application of retinoic acid ointment after the second operation achieved a good prognosis after 2 years of follow-up.CASE SUMMARY A 76-year-old male patient was admitted to the hospital for"lower lip rupture and scab for 3 mo".Treatment:A rectangular incision was made in the healthy tissue about 3 mm outside the periphery of the lower lip mass,and a modified Bernard sliding flap was designed to completely remove the mass.Pathology showed(lower lip)KA.When the patient returned 6 mo after surgery,the middle mucosa of the lower lip had a bulge with a diameter of about 0.5 cm.The boundary was still clear,the surface was ulcerated.A recurrence of lower lip KA was suspected and a fan-shaped incision was performed in the healthy tissue about 5 mm outside the lesion to completely resect.Pathological showed lower lip KA had recurred.Topical application of tretinoin cream was applied once a day for 3 mo.The lower lip wounds were clean at the 2-year postoperative follow-up and the mucosa was normal.CONCLUSION Adjuvant retinoic acid treatment after KA surgical resection can achieve good results.展开更多
We herein report a glycogen-rich adenocarcinoma occurring in the lower lip of a 44-year-old female. The lesion appeared as painless slowly growing mass in the right side of the lower lip. Histologically, infil-trative...We herein report a glycogen-rich adenocarcinoma occurring in the lower lip of a 44-year-old female. The lesion appeared as painless slowly growing mass in the right side of the lower lip. Histologically, infil-trative tumor nests with duct-like or pseudocyst structure into the mucosa and/or dermis were ob-served. The basaloid neoplastic cells had granular but occasionally vacuolated cytoplasm with salient reaction of diastase-digestible periodic acid-Schiff, thus indicating that they were glycogen-rich in nature. The tumor cells were positive for CEA, cytokeratin, and S-100 protein, and negative for SMA, alpha-1 antitrypsin, and amylase by immunohistochemistry. The origin of the tumor with infiltrative nests was indistinguishable from salivary gland and skin ap-pendage malignancy. A differential diagnosis of this peculiar neoplasm was discussed.展开更多
Squamous cell carcinoma (SCC) of the lower lip is a frequently diagnosed malignant pathology in the maxillofacial region. It is a slow-growing cancer, and can be diagnosed and treated easily and effectively;however, e...Squamous cell carcinoma (SCC) of the lower lip is a frequently diagnosed malignant pathology in the maxillofacial region. It is a slow-growing cancer, and can be diagnosed and treated easily and effectively;however, early treatment is important because its mortality rate is 10%-30%. Reconstruction for a large lower lip defect is surgically challenging, especially reconstruction with local flaps. Here, we present a 52-year-old male with a large T3 SCC, which started 13 years before this treatment and involved nearly all of his lower lip, oral commissure and upper lip. It was reconstructed by local flaps with good aesthetic and functional results. The lip was reconstructed with a combination of a Karapandzic flap on one side and a contralateral Webster cheek advancement, using a functional neck dissection on the tumor side and supraomohyoid neck dissection contralaterally. Histopathology results of the neck were negative for metastasis. We were satisfied with the aesthetic and functional results of the neck.展开更多
文摘Congenital unilateral lower lip palsy(CULLP),or congenital hypoplasia of the depressor anguli oris muscle,also known as asymmetric crying facies,is a rare condition that results in asymmetry of the lower lip during smiling,laughing,and crying.Although the etiology is unknown,weakness of the depressor labii inferioris(DLI)muscle is implicated as a contributing factor.Currently,no well-established treatment options are available.This case report describes an 18-year-old male patient diagnosed with CULLP.Physical examination revealed a symmetric face at rest,but asymmetry when smiling and opening the mouth.Following the administration of lidocaine into the affected DLI muscle,the patient’s smile and lower lip symmetry were immediately restored without any adverse effects.Subsequently,administration of botulinum toxin for neuromodulation of the DLI muscle led to a significant improvement in symmetry and oral function within 2 weeks,which was sustained at 1 month and 3 months post-treatment.No adverse effects were reported,and both patients and families expressed high satisfaction with the outcomes.This case highlights the potential use of neuromodulation as a minimally invasive and effective treatment for CULLP.
文摘Introduction: Squamous cell carcinomas of the lip essentially pose a therapeutic management problem. In the West, their treatment is done under general anesthesia and follows the classic rules of oncology. In our context of exercise, we sometimes have a different attitude dictated by various constraints. Observation: 55-year-old patient with no notable history, seen in consultation for a very large ulcerative-budding lesion on the right 2/3 of the lower lip with mucocutaneous involvement without lymph node findings found on examination. Faced with this suspicious lesion and the patient’s financial difficulties, we decided to operate under local anesthesia to remove this tumor. The oncological excision was followed by immediate plasty using a Camille-Bernard flap with a good immediate aesthetic and functional result and postoperative day 7. The patient was unable to take his surgical specimen to anatomy-pathology and was lost to follow-up due to lack of financial resources. On anatomo-pathological analysis of the surgical specimen, the margins were healthy with confirmation of squamous cell carcinoma (anapathological reading made for scientific interest). Discussion: The particular mentality of certain patients and their difficult financial conditions push us to have an unconventional therapeutic attitude in oncology, but which nevertheless makes it possible to resolve certain problems that we often face. Local anesthesia is possible and realistic in cases like ours and the results can be acceptable and life-saving.
文摘BACKGROUND This paper introduces a case of recurrent keratoacanthoma(KA).KA is a selfhealing disease.Recurrence after surgical resection is rare.In this case,the local application of retinoic acid ointment after the second operation achieved a good prognosis after 2 years of follow-up.CASE SUMMARY A 76-year-old male patient was admitted to the hospital for"lower lip rupture and scab for 3 mo".Treatment:A rectangular incision was made in the healthy tissue about 3 mm outside the periphery of the lower lip mass,and a modified Bernard sliding flap was designed to completely remove the mass.Pathology showed(lower lip)KA.When the patient returned 6 mo after surgery,the middle mucosa of the lower lip had a bulge with a diameter of about 0.5 cm.The boundary was still clear,the surface was ulcerated.A recurrence of lower lip KA was suspected and a fan-shaped incision was performed in the healthy tissue about 5 mm outside the lesion to completely resect.Pathological showed lower lip KA had recurred.Topical application of tretinoin cream was applied once a day for 3 mo.The lower lip wounds were clean at the 2-year postoperative follow-up and the mucosa was normal.CONCLUSION Adjuvant retinoic acid treatment after KA surgical resection can achieve good results.
文摘We herein report a glycogen-rich adenocarcinoma occurring in the lower lip of a 44-year-old female. The lesion appeared as painless slowly growing mass in the right side of the lower lip. Histologically, infil-trative tumor nests with duct-like or pseudocyst structure into the mucosa and/or dermis were ob-served. The basaloid neoplastic cells had granular but occasionally vacuolated cytoplasm with salient reaction of diastase-digestible periodic acid-Schiff, thus indicating that they were glycogen-rich in nature. The tumor cells were positive for CEA, cytokeratin, and S-100 protein, and negative for SMA, alpha-1 antitrypsin, and amylase by immunohistochemistry. The origin of the tumor with infiltrative nests was indistinguishable from salivary gland and skin ap-pendage malignancy. A differential diagnosis of this peculiar neoplasm was discussed.
文摘Squamous cell carcinoma (SCC) of the lower lip is a frequently diagnosed malignant pathology in the maxillofacial region. It is a slow-growing cancer, and can be diagnosed and treated easily and effectively;however, early treatment is important because its mortality rate is 10%-30%. Reconstruction for a large lower lip defect is surgically challenging, especially reconstruction with local flaps. Here, we present a 52-year-old male with a large T3 SCC, which started 13 years before this treatment and involved nearly all of his lower lip, oral commissure and upper lip. It was reconstructed by local flaps with good aesthetic and functional results. The lip was reconstructed with a combination of a Karapandzic flap on one side and a contralateral Webster cheek advancement, using a functional neck dissection on the tumor side and supraomohyoid neck dissection contralaterally. Histopathology results of the neck were negative for metastasis. We were satisfied with the aesthetic and functional results of the neck.
