A gated recurrent unit model to predict Poisson’s ratio using deep learning

Static Poisson’s ratio(vs)is crucial for determining geomechanical properties in petroleum applications,namely sand production.Some models have been used to predict vs;however,the published models were limited to specific data ranges with an average absolute percentage relative error(AAPRE)of more than 10%.The published gated recurrent unit(GRU)models do not consider trend analysis to show physical behaviors.In this study,we aim to develop a GRU model using trend analysis and three inputs for predicting n s based on a broad range of data,n s(value of 0.1627-0.4492),bulk formation density(RHOB)(0.315-2.994 g/mL),compressional time(DTc)(44.43-186.9 μs/ft),and shear time(DTs)(72.9-341.2μ s/ft).The GRU model was evaluated using different approaches,including statistical error an-alyses.The GRU model showed the proper trends,and the model data ranges were wider than previous ones.The GRU model has the largest correlation coefficient(R)of 0.967 and the lowest AAPRE,average percent relative error(APRE),root mean square error(RMSE),and standard deviation(SD)of 3.228%,1.054%,4.389,and 0.013,respectively,compared to other models.The GRU model has a high accuracy for the different datasets:training,validation,testing,and the whole datasets with R and AAPRE values were 0.981 and 2.601%,0.966 and 3.274%,0.967 and 3.228%,and 0.977 and 2.861%,respectively.The group error analyses of all inputs show that the GRU model has less than 5% AAPRE for all input ranges,which is superior to other models that have different AAPRE values of more than 10% at various ranges of inputs.

Differential diagnosis of Crohn’s disease and intestinal tuberculosis based on ATR-FTIR spectroscopy combined with machine learning

BACKGROUND Crohn’s disease(CD)is often misdiagnosed as intestinal tuberculosis(ITB).However,the treatment and prognosis of these two diseases are dramatically different.Therefore,it is important to develop a method to identify CD and ITB with high accuracy,specificity,and speed.AIM To develop a method to identify CD and ITB with high accuracy,specificity,and speed.METHODS A total of 72 paraffin wax-embedded tissue sections were pathologically and clinically diagnosed as CD or ITB.Paraffin wax-embedded tissue sections were attached to a metal coating and measured using attenuated total reflectance fourier transform infrared spectroscopy at mid-infrared wavelengths combined with XGBoost for differential diagnosis.RESULTS The results showed that the paraffin wax-embedded specimens of CD and ITB were significantly different in their spectral signals at 1074 cm^(-1) and 1234 cm^(-1) bands,and the differential diagnosis model based on spectral characteristics combined with machine learning showed accuracy,specificity,and sensitivity of 91.84%,92.59%,and 90.90%,respectively,for the differential diagnosis of CD and ITB.CONCLUSION Information on the mid-infrared region can reveal the different histological components of CD and ITB at the molecular level,and spectral analysis combined with machine learning to establish a diagnostic model is expected to become a new method for the differential diagnosis of CD and ITB.

Machine learning in predicting postoperative complications in Crohn’s disease

Crohn's disease(CD)is a chronic inflammatory bowel disease of unknown origin that can cause significant disability and morbidity with its progression.Due to the unique nature of CD,surgery is often necessary for many patients during their lifetime,and the incidence of postoperative complications is high,which can affect the prognosis of patients.Therefore,it is essential to identify and manage post-operative complications.Machine learning(ML)has become increasingly im-portant in the medical field,and ML-based models can be used to predict post-operative complications of intestinal resection for CD.Recently,a valuable article titled“Predicting short-term major postoperative complications in intestinal resection for Crohn's disease:A machine learning-based study”was published by Wang et al.We appreciate the authors'creative work,and we are willing to share our views and discuss them with the authors.

Machine learning as a tool predicting short-term postoperative complications in Crohn’s disease patients undergoing intestinal resection: What frontiers?

The recent study,“Predicting short-term major postoperative complications in intestinal resection for Crohn’s disease:A machine learning-based study”invest-igated the predictive efficacy of a machine learning model for major postoperative complications within 30 days of surgery in Crohn’s disease(CD)patients.Em-ploying a random forest analysis and Shapley Additive Explanations,the study prioritizes factors such as preoperative nutritional status,operative time,and CD activity index.Despite the retrospective design’s limitations,the model’s robu-stness,with area under the curve values surpassing 0.8,highlights its clinical potential.The findings align with literature supporting preoperative nutritional therapy in inflammatory bowel diseases,emphasizing the importance of compre-hensive assessment and optimization.While a significant advancement,further research is crucial for refining preoperative strategies in CD patients.

基于思维品质培养的小学英语词汇教学策略探究——以Unit 5 Dinner’s ready Let’s learn板块为例

以改善目前小学英语词汇教学中思维品质培养意识淡薄的问题为切入点,以PEP小学《英语》四年级(上)Unit 5 Dinner’s ready Let’slearn板块为例,探究如何依托主题与英语学习活动观,在词汇教学中培养学生的思维品质。提出教师应增强Let’slearn板块词汇教学的思维引领与进阶的育人作用,助力学生英语学科核心素养的协调发展。

Evaluation of Technical Education by Using a Modern Structured MOODLE Laboratory Course, in Relation to Recent Data

E-learning platforms support education systems worldwide, transferring theoretical knowledge as well as soft skills. In the present study high-school pupils’, and adult students’ opinions were evaluated through a modern structured MOODLE interactive course, designed for the needs of the laboratory course “Automotive Systems”. The study concerns Greek secondary vocational education pupils aged 18 and vocational training adult students aged 20 to 50 years. The multistage, equal size simple random cluster sample was used as a sampling method. Pupils and adult students of each cluster completed structured 10-question questionnaires both before and after attending the course. A total of 120 questionnaires were collected. In general, our findings disclosed that the majority of pupils and adult students had significantly improved their knowledge and skills from using MOODLE. They reported strengthening conventional teaching, using the new MOODLE technology. The satisfaction indices improved quite, with the differences in their mean values being statistically significant.

Decoding degeneration:the implementation of machine learning for clinical detection of neurodegenerative disorders

Machine learning represents a growing subfield of artificial intelligence with much promise in the diagnosis,treatment,and tracking of complex conditions,including neurodegenerative disorders such as Alzheimer’s and Parkinson’s diseases.While no definitive methods of diagnosis or treatment exist for either disease,researchers have implemented machine learning algorithms with neuroimaging and motion-tracking technology to analyze pathologically relevant symptoms and biomarkers.Deep learning algorithms such as neural networks and complex combined architectures have proven capable of tracking disease-linked changes in brain structure and physiology as well as patient motor and cognitive symptoms and responses to treatment.However,such techniques require further development aimed at improving transparency,adaptability,and reproducibility.In this review,we provide an overview of existing neuroimaging technologies and supervised and unsupervised machine learning techniques with their current applications in the context of Alzheimer’s and Parkinson’s diseases.

Detection of Alzheimer’s disease onset using MRI and PET neuroimaging:longitudinal data analysis and machine learning

The scientists are dedicated to studying the detection of Alzheimer’s disease onset to find a cure, or at the very least, medication that can slow the progression of the disease. This article explores the effectiveness of longitudinal data analysis, artificial intelligence, and machine learning approaches based on magnetic resonance imaging and positron emission tomography neuroimaging modalities for progression estimation and the detection of Alzheimer’s disease onset. The significance of feature extraction in highly complex neuroimaging data, identification of vulnerable brain regions, and the determination of the threshold values for plaques, tangles, and neurodegeneration of these regions will extensively be evaluated. Developing automated methods to improve the aforementioned research areas would enable specialists to determine the progression of the disease and find the link between the biomarkers and more accurate detection of Alzheimer’s disease onset.

Comparison and development of machine learning for thalidomideinduced peripheral neuropathy prediction of refractory Crohn’s disease in Chinese population

BACKGROUND Thalidomide is an effective treatment for refractory Crohn’s disease(CD).However,thalidomide-induced peripheral neuropathy(TiPN),which has a large individual variation,is a major cause of treatment failure.TiPN is rarely predictable and recognized,especially in CD.It is necessary to develop a risk model to predict TiPN occurrence.AIM To develop and compare a predictive model of TiPN using machine learning based on comprehensive clinical and genetic variables.METHODS A retrospective cohort of 164 CD patients from January 2016 to June 2022 was used to establish the model.The National Cancer Institute Common Toxicity Criteria Sensory Scale(version 4.0)was used to assess TiPN.With 18 clinical features and 150 genetic variables,five predictive models were established and evaluated by the confusion matrix receiver operating characteristic curve(AUROC),area under the precision-recall curve(AUPRC),specificity,sensitivity(recall rate),precision,accuracy,and F1 score.RESULTS The top-ranking five risk variables associated with TiPN were interleukin-12 rs1353248[P=0.0004,odds ratio(OR):8.983,95%confidence interval(CI):2.497-30.90],dose(mg/d,P=0.002),brainderived neurotrophic factor(BDNF)rs2030324(P=0.001,OR:3.164,95%CI:1.561-6.434),BDNF rs6265(P=0.001,OR:3.150,95%CI:1.546-6.073)and BDNF rs11030104(P=0.001,OR:3.091,95%CI:1.525-5.960).In the training set,gradient boosting decision tree(GBDT),extremely random trees(ET),random forest,logistic regression and extreme gradient boosting(XGBoost)obtained AUROC values>0.90 and AUPRC>0.87.Among these models,XGBoost and GBDT obtained the first two highest AUROC(0.90 and 1),AUPRC(0.98 and 1),accuracy(0.96 and 0.98),precision(0.90 and 0.95),F1 score(0.95 and 0.98),specificity(0.94 and 0.97),and sensitivity(1).In the validation set,XGBoost algorithm exhibited the best predictive performance with the highest specificity(0.857),accuracy(0.818),AUPRC(0.86)and AUROC(0.89).ET and GBDT obtained the highest sensitivity(1)and F1 score(0.8).Overall,compared with other state-of-the-art classifiers such as ET,GBDT and RF,XGBoost algorithm not only showed a more stable performance,but also yielded higher ROC-AUC and PRC-AUC scores,demonstrating its high accuracy in prediction of TiPN occurrence.CONCLUSION The powerful XGBoost algorithm accurately predicts TiPN using 18 clinical features and 14 genetic variables.With the ability to identify high-risk patients using single nucleotide polymorphisms,it offers a feasible option for improving thalidomide efficacy in CD patients.

Alzheimer’s Disease Stage Classification Using a Deep Transfer Learning and Sparse Auto Encoder Method

Alzheimer’s Disease(AD)is a progressive neurological disease.Early diagnosis of this illness using conventional methods is very challenging.Deep Learning(DL)is one of the finest solutions for improving diagnostic procedures’performance and forecast accuracy.The disease’s widespread distribution and elevated mortality rate demonstrate its significance in the older-onset and younger-onset age groups.In light of research investigations,it is vital to consider age as one of the key criteria when choosing the subjects.The younger subjects are more susceptible to the perishable side than the older onset.The proposed investigation concentrated on the younger onset.The research used deep learning models and neuroimages to diagnose and categorize the disease at its early stages automatically.The proposed work is executed in three steps.The 3D input images must first undergo image pre-processing using Weiner filtering and Contrast Limited Adaptive Histogram Equalization(CLAHE)methods.The Transfer Learning(TL)models extract features,which are subsequently compressed using cascaded Auto Encoders(AE).The final phase entails using a Deep Neural Network(DNN)to classify the phases of AD.The model was trained and tested to classify the five stages of AD.The ensemble ResNet-18 and sparse autoencoder with DNN model achieved an accuracy of 98.54%.The method is compared to state-of-the-art approaches to validate its efficacy and performance.

改进YOLOX-s的密集垃圾检测方法

针对密集堆放的多种类垃圾检测存在识别率低、定位不够准确和待测目标被误检、漏检问题,提出了一种融合多头自注意力机制改进YOLOX-s的垃圾检测方法。在特征提取网络嵌入SwinTransformer模块,引入基于滑窗操作的多头自注意力机制,使得网络兼顾全局特征信息和重点特征信息,减少误检现象;在预测输出网络中使用可变形卷积,对初始预测框进行精细化处理,提高定位精度;在EIoU损失的基础上引入加权系数,提出加权IoU-EIoU损失,自适应调整训练时不同阶段不同损失的关注程度,进一步加快训练网络的收敛速度。在公开204类垃圾检测数据集中进行测试,结果表明,所提改进算法的平均精度均值分别可达80.5%和92.5%,优于当前流行目标检测算法,且检测速度快,满足实时性需求。

Implicit Continuous User Authentication for Mobile Devices based on Deep Reinforcement Learning

The predominant method for smart phone accessing is confined to methods directing the authentication by means of Point-of-Entry that heavily depend on physiological biometrics like,fingerprint or face.Implicit continuous authentication initiating to be loftier to conventional authentication mechanisms by continuously confirming users’identities on continuing basis and mark the instant at which an illegitimate hacker grasps dominance of the session.However,divergent issues remain unaddressed.This research aims to investigate the power of Deep Reinforcement Learning technique to implicit continuous authentication for mobile devices using a method called,Gaussian Weighted Cauchy Kriging-based Continuous Czekanowski’s(GWCK-CC).First,a Gaussian Weighted Non-local Mean Filter Preprocessing model is applied for reducing the noise pre-sent in the raw input face images.Cauchy Kriging Regression function is employed to reduce the dimensionality.Finally,Continuous Czekanowski’s Clas-sification is utilized for proficient classification between the genuine user and attacker.By this way,the proposed GWCK-CC method achieves accurate authen-tication with minimum error rate and time.Experimental assessment of the pro-posed GWCK-CC method and existing methods are carried out with different factors by using UMDAA-02 Face Dataset.The results confirm that the proposed GWCK-CC method enhances authentication accuracy,by 9%,reduces the authen-tication time,and error rate by 44%,and 43%as compared to the existing methods.

Privacy Preserved Brain Disorder Diagnosis Using Federated Learning

Federated learning has recently attracted significant attention as a cutting-edge technology that enables Artificial Intelligence(AI)algorithms to utilize global learning across the data of numerous individuals while safeguarding user data privacy.Recent advanced healthcare technologies have enabled the early diagnosis of various cognitive ailments like Parkinson’s.Adequate user data is frequently used to train machine learning models for healthcare systems to track the health status of patients.The healthcare industry faces two significant challenges:security and privacy issues and the personalization of cloud-trained AI models.This paper proposes a Deep Neural Network(DNN)based approach embedded in a federated learning framework to detect and diagnose brain disorders.We extracted the data from the database of Kay Elemetrics voice disordered and divided the data into two windows to create training models for two clients,each with different data.To lessen the over-fitting aspect,every client reviewed the outcomes in three rounds.The proposed model identifies brain disorders without jeopardizing privacy and security.The results reveal that the global model achieves an accuracy of 82.82%for detecting brain disorders while preserving privacy.

基于LUS-PSO权重优化的入侵检测技术研究

机器学习中,多个分类器的组合称为集成分类器,此方法优于单个分类器。特定数据集找到合适的集成配置仍然是非常困难。基于这个问题,提出LUS-PSO权重优化的方法,使用粒子群算法生成的权重,进而生成更加准确的分类器集合。然后局部单峰采样方法作为元优化器,查找粒子群算法更好的行为参数。集成学习的分类器由该方法和加权多数投票共同决定的。实验结果表明,该检测模型生成的分类器在分类准确率方面更优。

Xception-Fractalnet:Hybrid Deep Learning Based Multi-Class Classification of Alzheimer’s Disease

Neurological disorders such as Alzheimer’s disease(AD)are very challenging to treat due to their sensitivity,technical challenges during surgery,and high expenses.The complexity of the brain structures makes it difficult to distinguish between the various brain tissues and categorize AD using conventional classification methods.Furthermore,conventional approaches take a lot of time and might not always be precise.Hence,a suitable classification framework with brain imaging may produce more accurate findings for early diagnosis of AD.Therefore in this paper,an effective hybrid Xception and Fractalnet-based deep learning framework are implemented to classify the stages of AD into five classes.Initially,a network based on Unet++is built to segment the tissues of the brain.Then,using the segmented tissue components as input,the Xception-based deep learning technique is employed to extract high-level features.Finally,the optimized Fractalnet framework is used to categorize the disease condition using the acquired characteristics.The proposed strategy is tested on the Alzheimer’s Disease Neuroimaging Initiative(ADNI)dataset that accurately segments brain tissues with a 98.45%of dice similarity coefficient(DSC).Additionally,for themulticlass classification of AD,the suggested technique obtains an accuracy of 99.06%.Moreover,ANOVA statistical analysis is also used to evaluate if the groups are significant or not.The findings show that the suggested model outperforms various stateof-the-art methods in terms of several performance metrics.

Research on Federated Learning Data Sharing Scheme Based on Differential Privacy

To realize data sharing,and to fully use the data value,breaking the data island between institutions to realize data collaboration has become a new sharing mode.This paper proposed a distributed data security sharing scheme based on C/S communication mode,and constructed a federated learning architecture that uses differential privacy technology to protect training parameters.Clients do not need to share local data,and they only need to upload the trained model parameters to achieve data sharing.In the process of training,a distributed parameter update mechanism is introduced.The server is mainly responsible for issuing training commands and parameters,and aggregating the local model parameters uploaded by the clients.The client mainly uses the stochastic gradient descent algorithm for gradient trimming,updates,and transmits the trained model parameters back to the server after differential processing.To test the performance of the scheme,in the application scenario where many medical institutions jointly train the disease detection system,the model is tested from multiple perspectives by taking medical data as an example.From the testing results,we can know that for this specific test dataset,when the parameters are properly configured,the lowest prediction accuracy rate is 90.261%and the highest accuracy rate is up to 94.352.It shows that the performance of the model is good.The results also show that this scheme realizes data sharing while protecting data privacy,completes accurate prediction of diseases,and has a good effect.

Prediction of the Wastewater’s pH Based on Deep Learning Incorporating Sliding Windows

To protect the environment,the discharged sewage’s quality must meet the state’s discharge standards.There are many water quality indicators,and the pH(Potential of Hydrogen)value is one of them.The natural water’s pH value is 6.0–8.5.The sewage treatment plant uses some data in the sewage treatment process to monitor and predict whether wastewater’s pH value will exceed the standard.This paper aims to study the deep learning prediction model of wastewater’s pH.Firstly,the research uses the random forest method to select the data features and then,based on the sliding window,convert the data set into a time series which is the input of the deep learning training model.Secondly,by analyzing and comparing relevant references,this paper believes that the CNN(Convolutional Neural Network)model is better at nonlinear data modeling and constructs a CNN model including the convolution and pooling layers.After alternating the combination of the convolutional layer and pooling layer,all features are integrated into a full-connected neural network.Thirdly,the number of input samples of the CNN model directly affects the prediction effect of the model.Therefore,this paper adopts the sliding window method to study the optimal size.Many experimental results show that the optimal prediction model can be obtained when alternating six convolutional layers and three pooling layers.The last full-connection layer contains two layers and 64 neurons per layer.The sliding window size selects as 12.Finally,the research has carried out data prediction based on the optimal CNN deep learning model.The predicted pH of the sewage is between 7.2 and 8.6 in this paper.The result is applied in the monitoring system platform of the“Intelligent operation and maintenance platform of the reclaimed water plant.”

A Survey of Major English Versions of Lu Xun’s Short Stories in the 20th Century

Lu Xun(1881-1936)has been acclaimed father of modern Chinese literature.He is the first writer to use the vernacular to write fiction.His stories have laid a solid foundation for the development of modern Chinese fiction.Call to Arms(1923)and Wandering(1926)represent the greatest achievement of Chinese story-writing at that time.His short stories are not only profound in thinking,but also worthy of admiration for their great value and innovation in art.Since the 1920’s,Lu Xun’s stories have been translated into various languages and published throughout the world,enjoying an international reputation.Only their English versions in the 20th century are discussed within this paper.These versions are different with various features,especially in dealing with Chinese traditional culture according to different purposes and towards different English readers.

A Survey of Feautures of Three English Versions of Lu Xun’s Short Stories

Lu Xun(1881-1936)has been acclaimed father of modern Chinese literature.He is the first writer to use the vernacular to write fiction.His stories have laid a solid foundation for the development of modern Chinese fiction.Call to Arms(1923)and Wandering(1926)represent the greatest achievement of Chinese story-writing at that time.Since the 1920’s,Lu Xun’s stories have been translated into various languages and published throughout the world,enjoying an international reputation.The three English versions chosen are different with various features,especially in dealing with Chinese traditional culture according to different purposes and towards different English readers.

Protective effect of tetrahydroxy stilbene glucoside on learning and memory by regulating synaptic plasticity

Damage to synaptic plasticity induced by neurotoxicity of amyloid-beta is regarded to be one of the pathological mechanisms of learning and memory disabilities in Alzheimer＇s disease patients. This study assumed that the damage of amyloid-beta to learning and memory abilities was strongly associated with the changes in the Fyn/N-methyl-D-aspartate receptor 2B （NR2B） expression. An APP695V7171 transgenic mouse model of Alzheimer＇s disease was used and treatment with tetrahydroxy-stilbene glucoside was administered intragas- trically. Results showed that intragastric administration of tetrahydroxy-stilbene glucoside improved the learning and memory abilities of the transgenic mice through increasing NR2B receptors and Fyn expression. It also reversed parameters for synaptic interface structure of gray type I. These findings indicate that tetrahydroxy stilbene glucoside has protective effects on the brain, and has prospects for its clinical application to improve the learning and memory abilities and treat Alzheimer＇s disease.