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A Giant Granuloma of the Vocal Process after Double-Lumen Bronchial Catheter Insertion: A Rare Case Report and Literature Review
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作者 Xiaoqin Zeng Xiaoyu Xi +3 位作者 Shun Guo Ya Zhao Bo Li Rui Xia 《Case Reports in Clinical Medicine》 2023年第12期464-476,共13页
Background: Double-lumen endotracheal (DLT) is commonly used for one-lung ventilation and lung separation during thoracic surgery. There are case reports of medically induced laryngeal granulomas, mainly in patients a... Background: Double-lumen endotracheal (DLT) is commonly used for one-lung ventilation and lung separation during thoracic surgery. There are case reports of medically induced laryngeal granulomas, mainly in patients after single-lumen endotracheal (SLT) tube intubation and tracheotomy, and giant granulomas of the vocal cords due to double-lumen bronchial tube insertion have rarely been reported. Case presentation: A 49-year-old female patient underwent single-port thoracoscopy after DLT intubation as well as a wedge resection of the lower lobe of the left lung, which caused giant vocal process granulomas (VPGs) postoperatively. Based on a retrospective analysis of the general condition, current medical history, past medical history, and visual laryngoscopic observation of the vocal folds tissue, which ruled out preoperative vocal fold granuloma formation, we hypothesized that double-lumen bronchial catheter intubation may have been the primary cause of her vocal fold granuloma formation. Conclusions: Giant granuloma of the vocal folds after DLT insertion is a rare postoperative complication;therefore, if DLT intubation is to be performed, the anesthesiologist should choose an appropriate intubation plan and deal with it promptly to avoid the risk factors to ensure that the patient’s perioperative period is safe and smooth. In addition, if postoperative complications are encountered, they should be followed up and observed on time. 展开更多
关键词 Vocal Process Granulomas Double-lumen Endotracheal Single-lumen Endotracheal Case Report
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基于实时渲染技术的室内家居设计研究——以Lumen技术为例
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作者 蒋叙 吴智慧 《艺术科技》 2023年第19期19-22,共4页
长期以来,家居消费需求存在一定的定性,虽然受到不稳定因素影响,但是消费者对定制家具、家居设计的消费需求从未消失.家居消费主体的转变带来消费观念的改变,线上与线下融合的消费方式成为时代主流,成为家居产业的一个重要发展趋势.新... 长期以来,家居消费需求存在一定的定性,虽然受到不稳定因素影响,但是消费者对定制家具、家居设计的消费需求从未消失.家居消费主体的转变带来消费观念的改变,线上与线下融合的消费方式成为时代主流,成为家居产业的一个重要发展趋势.新冠肺炎疫情迫使人们长期居家办公,进一步加速了家居产业的变革与升级,短视频、直播成为新型线上消费方式,全途径的营销方式成为企业发展的必然选择.与此同时,智能化、信息化、万物互联的新型商业模式,成为家居产业新的发展方向.渲染技术进一步发展,实时渲染技术趋于成熟,根据现阶段家具产品与室内装饰在展示上存在的展示方式单一、展示效果不真实等问题,提出实时渲染技术与室内家居设计结合,探寻室内家居设计的发展方向.文章通过分析现阶段家具产品和室内装饰的展示方式,指出室内家居设计在展示方面存在的问题,分析实时渲染技术的优势,以虚幻引擎(UE5,Unreal Engine 5)Lumen技术为例,结合具体家居设计案例分析,得出实时渲染技术能够弥补家居展示设计不足这一结论.实时渲染技术可以为家居展示设计提供更加便捷高效、展示效果更加出色的实现途径,提高设计效率,优化展示效果,为室内家居设计行业提供技术参考. 展开更多
关键词 实时渲染 UE5 lumen 室内家居设计
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Use of endolumenal functional lumen imaging probe in investigating paediatric gastrointestinal motility disorders
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作者 Emily White Mohamed Mutalib 《World Journal of Clinical Pediatrics》 2023年第4期162-170,共9页
Investigating gastrointestinal(GI)motility disorders relies on diagnostic tools to assess muscular contractions,peristalsis propagation and the integrity and coordination of various sphincters.Manometries are the gold... Investigating gastrointestinal(GI)motility disorders relies on diagnostic tools to assess muscular contractions,peristalsis propagation and the integrity and coordination of various sphincters.Manometries are the gold standard to study the GI motor function but it is increasingly acknowledged that manometries do not provide a complete picture in relation to sphincters competencies and muscle fibrosis.Endolumenal functional lumen imaging probe(EndoFLIP)an emerging technology,uses impedance planimetry to measure hollow organs cross sectional area,distensibility and compliance.It has been successfully used as a complementary tool in the assessment of the upper and lower oesophageal sphincters,oesophageal body,the pylorus and the anal canal.In this article,we aim to review the uses of EndoFLIP as a tool to investigate GI motility disorders with a special focus on paediatric practice.The majority of EndoFLIP studies were conducted in adult patients but the uptake of the technology in paediatrics is increasing.EndoFLIP can provide a useful complementary data to the existing GI motility investigation in both children and adults. 展开更多
关键词 Endolumenal functional lumen imaging probe PAEDIATRIC Gastrointestinal motility
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Double-Lumen Needle Follicular Flushing System versus Single-Lumen Aspiration Needle in IVF/ICSI Patients with Poor Ovarian Response: A Meta-Analysis
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作者 Weijie Xing Jianping Ou +1 位作者 Liuhong Cai Xin Tao 《Advances in Sexual Medicine》 2017年第4期167-178,共12页
Background: The present study performed a meta-analysis to comprehensively analyze existing randomized controlled trials (RCT) involving the use of double-lumen needle in patients with poor ovarian response to explore... Background: The present study performed a meta-analysis to comprehensively analyze existing randomized controlled trials (RCT) involving the use of double-lumen needle in patients with poor ovarian response to explore whether double-lumen needle was good for specific patients. Methods: The PubMed, EMBASE, Cochrane Library databases and two randomized controlled trials registration centers were thoroughly searched until April 2017. The clinical outcomes of IVF/ICSI cycles were compared between two groups with double-lumen needle and single-lumen needle. Results: Four RCT studies were included in this present meta-analysis. The oocytes yield was similar in two groups (OR 0.88, 95%CI 0.66 - 1.16;I2 = 4%). The procedure time with double-lumen needle was significantly longer than that with single-lumen needle (IV = 1.98, 95%CI 0.95 - 3.00;I2 = 86%). The fertilization rate with double-lumen needle was lower than that with single-lumen needle (OR 0.66, 95%CI 0.44 - 0.97;I2 = 0%). There was no significant difference of live birth rate in two groups (OR 0.76, 95%CI 0.32 - 1.76;I2 = 41%). Conclusion: Double-lumen needle could not benefit patients with a POR in terms of the number of oocytes retrieved, oocyte recovery rate, normal fertilization rate, clinical pregnancy rate, and live birth rate, compared with single-lumen needle. 展开更多
关键词 Double-lumen NEEDLE Single-lumen NEEDLE Poor Ovarian Response
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Vue.js与Lumen组合框架的大创项目管理系统架构方案 被引量:2
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作者 张惠烽 简国明 +3 位作者 刘明杰 陈晓峰 郭钰霞 陈秋彤 《信息技术与信息化》 2019年第8期34-36,39,共4页
针对高校大学生创新创业训练计划项目管理系统的需求,研究了Vue.js前端框架、Lumen后端框架以及前后端分离架构,结合当下主流Web技术,探索并设计出一套适用于大创项目管理系统的,并且应用Vue.js与Lumen框架的前后端分离的具有高效率、... 针对高校大学生创新创业训练计划项目管理系统的需求,研究了Vue.js前端框架、Lumen后端框架以及前后端分离架构,结合当下主流Web技术,探索并设计出一套适用于大创项目管理系统的,并且应用Vue.js与Lumen框架的前后端分离的具有高效率、高安全系数和低维护成本的系统架构方案。最后将该架构方案应用于实际项目中,通过实际测试验证该架构方案的应用价值。 展开更多
关键词 大创项目 架构方案 系统开发 Vue.js lumen
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Lumen apposing metal stents for pancreatic fluid collections:Recognition and management of complications 被引量:2
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作者 Michael L DeSimone Akwi W Asombang Tyler M Berzin 《World Journal of Gastrointestinal Endoscopy》 CAS 2017年第9期456-463,共8页
For patients recovering from acute pancreatitis,the development of a pancreatic fluid collection (PFC) predicts a more complex course of recovery,and introduces difficult management decisions with regard to when,wheth... For patients recovering from acute pancreatitis,the development of a pancreatic fluid collection (PFC) predicts a more complex course of recovery,and introduces difficult management decisions with regard to when,whether,and how the collection should be drained.Most PFCs resolve spontaneously and drainage is indicated only in pseudocysts and walled-off pancreatic necrosis when the collections are causing symptoms and/or local complications such as biliary obstruction.Historical approaches to PFC drainage have included surgical (open or laparoscopic cystgastrostomy or pancreatic debridement),and the placement of percutaneous drains.Endoscopic drainage techniques have emerged in the last several years as the preferred approach for most patients,when local expertise is available.Lumen-apposing metal stents(LAMS) have recently been developed as a tool to facilitate potentially safer and easier endoscopic drainage of pancreatic fluid collections,and less commonly,for other indications,such as gallbladder drainage.Physicians considering LAMS placement must be aware of the complications most commonly associated with LAMS including bleeding,migration,buried stent,stent occlusion,and perforation.Because of the patient complexity associated with severe pancreatitis,management of pancreatic fluid collections can be a complex and multidisciplinary endeavor.Successful and safe use of LAMS for patients with pancreatic fluid collections requires that the endoscopist have a full understanding of the potential complications of LAMS techniques,including how to recognize and manage expected complications. 展开更多
关键词 Pancreatic fluid collection lumen apposing metal stent Endoscopic necrosectomy Cystgastrostomy
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Lumen-apposing metal stents for malignant biliary obstruction: Is this the ultimate horizon of our experience? 被引量:4
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作者 Andrea Anderloni Edoardo Troncone +4 位作者 Alessandro Fugazza Annalisa Cappello Giovanna Del Vecchio Blanco Giovanni Monteleone Alessandro Repici 《World Journal of Gastroenterology》 SCIE CAS 2019年第29期3857-3869,共13页
In the last years, endoscopic ultrasonography (EUS) has evolved from a purely diagnostic technique to a more and more complex interventional procedure, with the possibility to perform several type of therapeutic inter... In the last years, endoscopic ultrasonography (EUS) has evolved from a purely diagnostic technique to a more and more complex interventional procedure, with the possibility to perform several type of therapeutic interventions. Among these, EUS-guided biliary drainage (BD) is gaining popularity as a therapeutic approach after failed endoscopic retrograde cholangiopancreatography in distal malignant biliary obstruction (MBO), due to the avoidance of external drainage, a lower rate of adverse events and re-interventions, and lower costs compared to percutaneous trans-hepatic BD. Initially, devices created for luminal procedures (e.g., luminal biliary stents) have been adapted to the new trans-luminal EUSguided interventions, with predictable shortcomings in technical success, outcome and adverse events. More recently, new metal stents specifically designed for transluminal drainage, namely lumen-apposing metal stents (LAMS), have been made available for EUS-guided procedures. An electrocautery enhanced delivery system (EC-LAMS), which allows direct access of the delivery system to the target lumen, has subsequently simplified the classic multi-step procedure of EUS-guided drainages. EUS-BD using LAMS and ECLAMS has been demonstrated effective and safe, and currently seems one of the most performing techniques for EUS-BD. In this Review, we summarize the evolution of the EUS-BD in distal MBO, focusing on the novelty of LAMS and analyzing the unresolved questions about the possible role of EUS as the first therapeutic option to achieve BD in this setting of patients. 展开更多
关键词 Interventional ENDOSCOPIC ULTRASONOGRAPHY ENDOSCOPIC ultrasonography-guided BILIARY drainage ENDOSCOPIC ultrasonography-guided choledocho-duodenostomy BILIARY METAL STENT lumen-apposing METAL STENT
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Total endovascular repair of an intraoperative stent-graft deployed in the false lumen of Stanford type A aortic dissection: A case report 被引量:2
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作者 Xu-Ran Li Yuan-Hao Tong +3 位作者 Xiao-Qiang Li Chang-Jian Liu Chen Liu Zhao Liu 《World Journal of Clinical Cases》 SCIE 2020年第5期954-962,共9页
BACKGROUND A 46-year-old male underwent ascending aortic replacement,total arch replacement,and descending aortic stent implantation for Stanford type A aortic dissection in 2016.However,an intraoperative stent-graft ... BACKGROUND A 46-year-old male underwent ascending aortic replacement,total arch replacement,and descending aortic stent implantation for Stanford type A aortic dissection in 2016.However,an intraoperative stent-graft was deployed in the false lumen inadvertently.This caused severe iatrogenic thoracic and abdominal aortic dissection,and the dissection involved many visceral arteries.CASE SUMMARY The patient had pain in the chest and back for 1 mo.A computed tomography scan showed that the patient had secondary thoracic and abdominal aortic dissection.The ascending aortic replacement,total arch replacement,and descending aortic stent implantation for Stanford type A aortic dissection were performed 2 years prior.An intraoperative stent-graft was deployed in the false lumen.Endovascular aneurysm repair was performed to address this intractable situation.An occluder was used to occlude the proximal end of the true lumen,and a covered stent was used to direct blood flow back to the true lumen.A three-dimensional printing technique was used in this operation to guide prefenestration.The computed tomography scan at the 1stmo after surgery showed that the thoracic and abdominal aortic dissection was repaired,with all visceral arteries remaining patent.The patient did not develop renal failure or neurological complications after surgery.CONCLUSION The total endovascular repair for false lumen stent-graft implantation was feasible and minimally invasive.Our procedures provided a new solution for stent-graft deployed in the false lumen,and other departments may be inspired by this case when they need to rescue a disastrous stent implantation. 展开更多
关键词 Type A dissection False lumen stent graft implantation Endovascular repair 3D printing Thoracoabdominal aortic dissection Case report
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Alternative uses of lumen apposing metal stents 被引量:1
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作者 Prabin Sharma Thomas R McCarty +5 位作者 Ankit Chhoda Antonio Costantino Caroline Loeser Thiruvengadam Muniraj Marvin Ryou Christopher C Thompson 《World Journal of Gastroenterology》 SCIE CAS 2020年第21期2715-2728,共14页
The advent of lumen apposing metal stents(LAMS)has revolutionized the management of many complex gastroenterological conditions that previously required surgical or radiological interventions.These procedures have gar... The advent of lumen apposing metal stents(LAMS)has revolutionized the management of many complex gastroenterological conditions that previously required surgical or radiological interventions.These procedures have garnered popularity due to their minimally invasive nature,higher technical and clinical success rate and lower rate of adverse events.By virtue of their unique design,LAMS provide more efficient drainage,serve as conduit for endoscopic access,are associated with lower rates of leakage and are easy to be removed.Initially used for drainage of pancreatic fluid collections,the use of LAMS has been extended to gallbladder and biliary drainage,treatment of luminal strictures,creation of gastrointestinal fistulae,pancreaticobiliary drainage,improved access for surgically altered anatomy,and drainage of intra-abdominal and pelvic abscesses as well as post-surgical fluid collections.As new indications of endosonographic techniques and LAMS continue to evolve,this review summarizes the current role of LAMS in the management of these various complex conditions and also highlights clinical pearls to guide successful placement of LAMS. 展开更多
关键词 lumen apposing metal stents Walled off necrosis Gallbladder drainage Biliary drainage Gastric access temporary for endoscopy Gastric outlet obstruction Therapeutic endoscopy
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A New Type of Double-Lumen Catheter to Replace Current One in RCA 被引量:1
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作者 Yingfeng Xue Zhenguo Yu 《International Journal of Clinical Medicine》 2016年第9期620-627,共8页
Objective: To replace the peripheral venous puncture for blood sampling with taking blood samples extracorporally from arterial line before predilution during RCA-CRRT performed. Methods: A new type of double-lumen fe... Objective: To replace the peripheral venous puncture for blood sampling with taking blood samples extracorporally from arterial line before predilution during RCA-CRRT performed. Methods: A new type of double-lumen femoral catheter was used instead of the current tubes. The new type of double-lumen tube had a greater distance from the inner venous ports to the inner arterial ports than current tubes. The minimum distance from the venous port to the arterial port was greatly lengthened. Replacement solution contained citrate, zero Ca<sup>2+</sup>, zero bicarbonate, low Na<sup>+</sup>. Blood samples were synchronously collected from the arterial line before the infusion of citrate replacement fluid and from the peripheral vein. The iCa concentration data of two groups were analyzed to observe the difference between iCa concentration levels in the arterial line and in peripheral vein;the anticoagulant effect of RCA and possible complications were observed, such as bleeding, clottings and hypocalcaemia. Results: 28 times of RCA-CRRT were performed on17 AKI and CRF patients with active bleeding or at the high risk of bleeding;336 blood samples were collected. Statistics showed that the difference of iCa concentration between arterial line group and the peripheral vein group was not significant (P = 0.9), there is a high degree of similarity between the iCa concentration of arterial line blood and the peripheral venous blood. None of the patients developed citrate toxicity or metabolic alkalosis. None induced bleeding, or bleeding aggravated. No obvious clotting occurred. Systemic calcium concentration was achieved in the ideal range. Conclusion: In clinical practice, the data of iCa concentration from arterial line can be used to replace that from peripheral vein when the new type of double-lumen femoral catheter is placed in femoral vein. RCA-CRRT therapy is safe and effective. 展开更多
关键词 RCA-CRRT Ionized Calcium Arterial Line Peripheral Vein New Type of Double-lumen Femoral Catheter
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Sphincterotomy by triple lumen needle knife using guide wire in patients with Billroth Ⅱ gastrectomy
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作者 Su Bum Park Hyung Wook Kim +4 位作者 Dae Hwan Kang Cheol Woong Choi Ki Tae Yoon Mong Cho Byeong Jun Song 《World Journal of Gastroenterology》 SCIE CAS 2013年第48期9405-9409,共5页
AIM:To investigate the usefulness of a guide wire and triple lumen needle knife for removing stones in BillrothⅡ(B-Ⅱ)gastrectomy patients.METHODS:Endoscopic sphincterotomy in patients with B-Ⅱgastrectomy is challen... AIM:To investigate the usefulness of a guide wire and triple lumen needle knife for removing stones in BillrothⅡ(B-Ⅱ)gastrectomy patients.METHODS:Endoscopic sphincterotomy in patients with B-Ⅱgastrectomy is challenging.We used a new guide wire technique involving sphincterotomy by triple lumen needle knife through a forward-viewing endoscopy.This technique was performed in nine patients between August 2010 and June 2012.Sphincterotomy as described above was performed.Adequate sphincterotomy,successful stone removal,and complications were investigated prospectively.RESULTS:Sphincterotomy by triple lumen needle knife using guide wire was successful in all nine patients.Sphincterotomy started towards the 4-5 o’clock direction and continued to the upper margin of the papillary roof.Complete stone removal in one session was achieved in all patients.There were no procedure related complications,such as bleeding,pancreatitis,or perforation.CONCLUSION:In patients with B-Ⅱgastrectomy,guide wire using sphincterotomy by triple lumen needle knife through a forward-viewing endoscopy seems to be an effective and safe procedure for the removal of common bile duct stones. 展开更多
关键词 BILLROTH GASTRECTOMY Endoscopic SPHINCTEROTOMY Forward-viewing endoscopy Guide wire Triple lumen NEEDLE KNIFE
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Off label use of lumen-apposing metal stent for persistent gastro-jejunal anastomotic stricture
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作者 Muhammad Sohail Mansoor Juan Tejada +2 位作者 Nour A Parsa Eric Yoon Sven Hida 《World Journal of Gastrointestinal Endoscopy》 CAS 2018年第6期117-120,共4页
We are reporting a novel "off-label" use of lumen apposing metal stent(LAMS) for management of refractory gastro-jejunal(GJ) anastomotic stricture after Roux-en-y gastric bypass(RYGB). With increasing preval... We are reporting a novel "off-label" use of lumen apposing metal stent(LAMS) for management of refractory gastro-jejunal(GJ) anastomotic stricture after Roux-en-y gastric bypass(RYGB). With increasing prevalence of obesity, bariatric surgery is performed more frequently than ever. RYGB is one of the most commonly performed bariatric procedures. GJ anastomotic stricture is a late complication of this procedure. Our patient, seven years after RYGB developed GJ anastomotic ulcer and subsequently a stricture not amendable to repeated pneumatic dilations. Instead of using the conventional fully covered self-expanding metal stent(fc SEMS) we deployed the relatively new LAMS keeping in mind its novel dumbbell shaped design. Our patient's symptoms were controlled successfully and she remained asymptomatic on follow-up. Despite initial approval for pancreatic pseudocyst drainage, LAMS has been used with increased frequency at various locations within gastrointestinal tract including GJ anastomotic strictures. Future randomized control trials are warranted to compare the efficacy of fcSEMS to LAMS. 展开更多
关键词 Gastro-jejunal anastomotic STRICTURE lumen apposing metal stent DYSPHAGIA ROUX-EN-Y gastric BYPASS
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Virtues of Using a Double Lumen Tube for Anesthesia in Patients with Endobronchial Tumours Requiring Open Lung Resection or Bronchoplastic Procedures
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作者 Assem Adel Moharram Hany Hasan Elsayed 《Open Journal of Anesthesiology》 2020年第1期1-12,共12页
Objective The benefits and risks of using double lumen tube (DLT) in open thoracotomy are not well studied and the relative contraindication for using it in cases of endobronchial tumours is not proven. In this study,... Objective The benefits and risks of using double lumen tube (DLT) in open thoracotomy are not well studied and the relative contraindication for using it in cases of endobronchial tumours is not proven. In this study, we compared our experience with using DLT versus single lumen tube (SLT) for anesthesia in patients requiring an open thoracotomy for resection of endobronchial tumours. Methods A prospective observational study was performed in a single tertiary care university hospital in patients with endobronchial tumours anesthetized with single and double lumen tubes for open thoracotomy procedures over a period from 2010 till 2018. Results One hundred and six patients with endobronchial tumours were studied. There were 76 males. Median age was 32 years (14 - 62). In 96 cases, endobronchial pathology was a typical carcinoid. 58 patients were anesthetized using a DLT and 48 using a SLT. Four cases of near miss from potentially fatal intraoperative tumour migration occurred in the SLT group (p = 0.025). There was only one case of mild tumour bleeding from the DLT group and time of insertion was longer (16.2 vs. 4.5 min p Conclusions We conclude that it is safe to place a double lumen endo tracheal tube for patients with endobronchial tumours requiring open lobectomies or bronchoplastic procedures. An additional benefit of DLT use is increasing surgical satisfaction by reducing spillage and tidal volume loss during surgical anastomosis of the open airway. 展开更多
关键词 Double lumen Tube ENDOBRONCHIAL TUMOR THORACOTOMY
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Proximal true lumen collapse in a chronic type B aortic dissection patient:A case report
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作者 Li Zhang Wei-Kang Guan +5 位作者 Hua-Ping Wu Xiang Li Kai-Ping Lv Cun-Liang Zeng Huan-Huan Song Qian-Ling Ye 《World Journal of Clinical Cases》 SCIE 2021年第34期10689-10695,共7页
BACKGROUND In the context of aortic dissection,increasing pressure within the newly formed false lumen can result in the progressive compression of the true aortic channel.However,true lumen collapse in chronic type B... BACKGROUND In the context of aortic dissection,increasing pressure within the newly formed false lumen can result in the progressive compression of the true aortic channel.However,true lumen collapse in chronic type B aortic dissection(cTBAD)patients is rare,with few clinical or experimental studies to date having explored the causes of such collapse.CASE SUMMARY In the present report,we describe a rare case of true-lumen collapse in an 83-yearold patient diagnosed with cTBAD,and we discuss potential therapeutic interventions for such cases.Following thoracic endovascular aortic repair(TEVAR),computed tomography angiography revealed satisfactory stent-graft positioning,no endoleakage,true lumen enlargement,thrombus formation in the false lumen,and slight enlargement of the true lumen distal to the stent-graft.Computational hemodynamic analyses indicated that the wall shear stress and pressure within the false lumen were significantly reduced following TEVAR.CONCLUSION TEVAR treatment of cTBAD patients suffering from proximal true lumen collapse can facilitate some degree of effective remodeling. 展开更多
关键词 True lumen collapse Chronic type B aortic dissection Thoracic endovascular repair Computational hemodynamics analysis Case report
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基于HR-MRI分析MCAS患者血管管壁特征与卒中的关系
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作者 王海波 王振全 +4 位作者 段宏伟 杨勇政 丁琦峰 孙英杰 周山 《中国CT和MRI杂志》 2024年第5期64-66,共3页
目的基于三维高分辨率磁共振(HR-MRI)分析大脑中动脉粥样硬化性狭窄(MCAS)患者血管管壁特征与卒中的关系。方法回顾性分析2020年4月~2023年4月我院收治的100例MCAS患者临床资料,根据病变血管是否引发卒中情况,将其分为责任血管组(引发... 目的基于三维高分辨率磁共振(HR-MRI)分析大脑中动脉粥样硬化性狭窄(MCAS)患者血管管壁特征与卒中的关系。方法回顾性分析2020年4月~2023年4月我院收治的100例MCAS患者临床资料,根据病变血管是否引发卒中情况,将其分为责任血管组(引发卒中的大脑中动脉,n=100)和非责任血管组(对侧未引发卒中的大脑中动脉,n=77),比较两组大脑中动脉斑块分布情况、斑块类型、斑块强化类型、斑块强化程度及管壁参数。结果100例MCAS患者中共发现227个斑块,其中责任血管组中有106个,非责任血管组中有121个;两组均以前壁斑块最为常见,但责任血管组上壁斑块所占比例(26.42%)明显高于非责任血管组(14.88%)(P<0.05)。责任血管组不规则斑块所占比例(63.21%)明显高于非责任血管组(43.80%)(P<0.05)。责任血管组偏心性强化斑块及高度强化斑块所占比例(84.91%、53.77%)明显高于非责任血管组(30.58%、8.26%),无强化和轻度强化斑块所占比例(7.55%、17.92%)明显低于非责任血管组(16.53%、43.80%),差异均有统计学意义(P<0.05)。责任血管组管腔狭窄程度、最大管壁厚度、管壁面积及斑块负荷均明显大于非责任血管组(P<0.05)。结论HR-MRI可清晰显示MCAS患者血管管壁特征,有助于评估斑块稳定性和识别责任血管,对预防卒中的发生具有一定参考价值。 展开更多
关键词 卒中 HR-MRI MCAS 管壁特征 最大管腔狭窄处 管壁参数
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改良鼻胃肠双腔管两步置管法在神经外科重症患者中的应用
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作者 杨斌 高宇飞 +4 位作者 武宝平 于雪 屈冲 秦治刚 赵航 《长春中医药大学学报》 2024年第2期197-200,共4页
目的探索一种改良的鼻胃肠双腔管置管两步法,可以床旁徒手完成置管应用于神经外科重症患者;方法收集需行肠内营养的神经外科重症患者120例,采用随机数表法分为传统鼻肠管组(对照组)和改良鼻肠双腔管组(改良组),各60例,分别记录入组时的A... 目的探索一种改良的鼻胃肠双腔管置管两步法,可以床旁徒手完成置管应用于神经外科重症患者;方法收集需行肠内营养的神经外科重症患者120例,采用随机数表法分为传统鼻肠管组(对照组)和改良鼻肠双腔管组(改良组),各60例,分别记录入组时的APACHEⅡ评分及GCS评分、年龄、体质量指数(BMI),收集每例患者鼻肠管置管操作时间,置管前心率及置管过程中的最高心率变化,置管前和置管后14 d的鼻窦CT、胸部CT及营养指标,判断是否出现鼻窦炎、吸入性肺炎、消化道出血、营养液潴留及心律失常等并发症。结果2组入组时APACHEⅡ评分,GCS评分,年龄,BMI比较,差异均无统计学意义(t=1.0598,1.2073,0.3104,0.9268;P=0.2914,0.2297,0.7568,0.3559,P均>0.05)。改良组置管时间(54.4±13)min,对照组置管时间(49.4±12.9)min,改良组置管时间略长于对照组(t=2.1334,P=0.035,P<0.05)。置管过程中,改良组和对照组在心率变化方面比较,差异无统计学意义(P>0.05)。改良组控制鼻窦炎(20.0%,12/60)方面优于对照组(36.7%,22/60)(P<0.05),改良组控制肺炎(26.7%,16/60)方面优于对照组(46.7%,28/60)(P<0.05),改良组控制胃液潴留(5.0%,3/60)方面优于对照组(16.7%,10/60)(P<0.05);2组胃肠道出血及心律失常方面比较,差异无统计学意义(P>0.05)。经过14 d的肠内营养治疗后,改良组白蛋白、前白蛋白、血红蛋白及淋巴细胞计数均好于对照组。结论改良的鼻胃肠双腔管两步置管法可在床头徒手完成,与传统方法比较,尽管置管时间略有延长,但鼻窦炎、吸入性肺炎的发生率明显降低,不增加置管相关并发症发生,同时改良组营养指标明显优于对照组。该两步法安全、有效、便捷,值得临床推广。 展开更多
关键词 神经重症 鼻胃肠双腔管 置管方法 徒手
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miR-let-7c-5p对膀胱癌细胞恶性行为、血管管腔形成及HMGB2的调控作用
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作者 刘辉勇 董铮 +1 位作者 徐涛 柳琦 《检验医学与临床》 CAS 2024年第8期1035-1040,共6页
目的探讨miR-let-7c-5p对膀胱癌细胞恶性行为、血管管腔形成及高迁移率族蛋白(HMGB)2的调控作用。方法将人膀胱癌UM-UC-3细胞分别进行常规培养(空白组)、转染mimics-NC(mimics-NC组)、转染miR-let-7c-5p-mimics(miR-let-7c-5p-mimics组... 目的探讨miR-let-7c-5p对膀胱癌细胞恶性行为、血管管腔形成及高迁移率族蛋白(HMGB)2的调控作用。方法将人膀胱癌UM-UC-3细胞分别进行常规培养(空白组)、转染mimics-NC(mimics-NC组)、转染miR-let-7c-5p-mimics(miR-let-7c-5p-mimics组)、转染inhibitor-NC(inhibitor-NC组)及转染miR-let-7c-5p-inhibitor(miR-let-7c-5p-inhibitor组)。采用实时荧光定量聚合酶链反应检测各组细胞miR-let-7c-5p转染成功率;采用Transwell法检测各组细胞侵袭能力;采用划痕试验检测各组细胞迁移能力;采用Matrigel胶小管形成试验检测各组细胞血管生成;采用免疫印迹法检测各组细胞HMGB2、血管内皮生长因子(VEGF)及葡萄糖转运蛋白-1(GLUT-1)蛋白表达水平;采用荧光素酶试验验证miR-let-7c-5p对HMGB2的调控作用。结果空白组、mimics-NC组及inhibitor-NC组miR-let-7c-5p mRNA表达水平、侵袭数目、划痕愈合率、血管管腔数目,HMGB2、VEGF及GLUT-1蛋白表达水平比较,差异均无统计学意义(P>0.05);与空白组、mimics-NC组及inhibitor-NC组比较,miR-let-7c-5p-mimics组miR-let-7c-5p mRNA表达水平升高,侵袭数目、划痕愈合率、血管管腔数目,HMGB2、VEGF及GLUT-1蛋白表达水平均降低,miR-let-7c-5p-inhibitor组miR-let-7c-5p mRNA表达水平降低,侵袭数目、划痕愈合率、血管管腔数目,HMGB2、VEGF及GLUT-1蛋白表达水平均升高,差异均有统计学意义(P<0.05)。荧光素酶试验结果显示,与mimics-NC组比较,miR-let-7c-5p-mimics组HMGB2-Wt水平降低,差异有统计学意义(P<0.05)。结论上调miR-let-7c-5p可明显抑制膀胱癌细胞侵袭、转移及血管生成,其机制与抑制HMGB2蛋白表达相关。 展开更多
关键词 膀胱癌 血管管腔 高迁移率族蛋白2 侵袭 转移 荧光素酶试验
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Endoscopic ultrasound-guided pancreatic fluid collection drainage: Where are we?
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作者 Anupam Kumar Singh Manish Manrai Rakesh Kochhar 《World Journal of Gastrointestinal Endoscopy》 2024年第6期273-281,共9页
Pancreatic fluid collections(PFCs)result from injury to the pancreas from acute or chronic pancreatitis,surgery,or trauma.Management of these collections has evolved over the last 2 decades.The choice of interventions... Pancreatic fluid collections(PFCs)result from injury to the pancreas from acute or chronic pancreatitis,surgery,or trauma.Management of these collections has evolved over the last 2 decades.The choice of interventions includes percu-taneous,endoscopic,minimally invasive surgery,or a combined approach.Endoscopic drainage is the drainage of PFCs by creating an artificial communi-cation between the collection and gastrointestinal lumen that is maintained by placing a stent across the fistulous tract.In this editorial,we endeavored to update the current status of endoscopic ultrasound-guided drainage of PFCs. 展开更多
关键词 Pancreatic fluid collections Endoscopic ultrasound-guided drainage Endoscopic necrosectomy lumen apposing metal stent Review
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Endoscopic ultrasound-guided gastroenterostomy for gastric outlet obstruction in Mexico
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作者 Massiel Madelin Rosario-Morel Rodrigo Soto-Solis +5 位作者 Katia Picazo-Ferrera Miriam Idalia Torres-Ruiz JoséAlberto Estradas-Trujillo Mario Alberto Gallardo-Ramírez Gerardo Akram Darwich-del Moral Luis Ariel Waller-González 《World Journal of Surgical Procedures》 2024年第3期15-20,共6页
BACKGROUND Endoscopic ultrasound-guided gastroenterostomy(EUS-GE)has recently emerged as an alternative treatment for gastric outlet obstruction(GOO)in selected patients.AIM To report the initial experience of EUS-GE ... BACKGROUND Endoscopic ultrasound-guided gastroenterostomy(EUS-GE)has recently emerged as an alternative treatment for gastric outlet obstruction(GOO)in selected patients.AIM To report the initial experience of EUS-GE in patients with GOO.METHODS This study was a retrospective,observational,multicenter study in which the data from 10 patients who underwent EUS-GE due to GOO between September 2021 and May 2023 were collected.We analyzed technical success,clinical success,adverse events,and survival.Technical success was defined as adequate positioning and deployment of the stent.Clinical success was defined as the patient’s ability to tolerate oral intake without vomiting 7 d after the procedure.Postprocedural adverse events were recorded.RESULTS Eleven procedures in 10 patients with GOO were included.The mean age of the patients was 67.5 years(range:56-77 years).Malignant GOO was present in 9 patients.Technical success was achieved in 9/11 procedures(82%).Among them,clinical success was achieved in 9 patients(100%).Adverse events occurred in 1 patient(9%).The median survival was 3 months(n=7;range:1-8 months).CONCLUSION EUS-GE is a feasible therapeutic option in the treatment of GOO. 展开更多
关键词 Endoscopic ultrasound-guided gastroenterostomy Gastric outlet obstruction lumen apposing metal stent Interventional endoscopic ultrasound GASTROJEJUNOSTOMY Duodenal stenting
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改良预先单肺通气加快胸腔镜手术肺萎陷的效果及安全性评价
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作者 黄晓峰 关银 +4 位作者 王鸿旻 王子铭 王雪洁 何平 黄生辉 《安徽医药》 CAS 2024年第6期1192-1197,共6页
目的评价改良预先单肺通气(OLV)在胸腔镜手术中加快术侧肺萎陷的效果及安全性。方法将2019年5月至2021年10月甘肃省肿瘤医院择期行肺楔形切除、肺叶切除术102例病人,按随机数字表法分配至常规OLV(C组)、预先OLV(P组)、改良预先OLV组(M... 目的评价改良预先单肺通气(OLV)在胸腔镜手术中加快术侧肺萎陷的效果及安全性。方法将2019年5月至2021年10月甘肃省肿瘤医院择期行肺楔形切除、肺叶切除术102例病人,按随机数字表法分配至常规OLV(C组)、预先OLV(P组)、改良预先OLV组(M组),每组34例。分别采用相应肺萎陷方法监测并记录病人胸腔开放后获得满意肺萎陷所需时间,胸腔开放后1、5、10、20、30 min肺萎陷评分,诱导前(T_(0))、插管后/膨肺前(T_(1))、侧卧前/膨肺末(T_(2))、侧卧后/膨肺后1 min(T_(3))、胸腔开放即刻(T_(4))、获得满意肺萎陷时刻(T_(5))的平均动脉压(MAP)、心率,T_(0)、T_(3)、T_(4)、T_(5)的脉搏血氧饱和度(SpO_(2))、动脉血氧分压(PaO_(2))、动脉血二氧化碳分压(PaCO_(2)),以及病人术中低氧血症发生、血管活性药物使用、术后肺部并发症及住院天数等情况。结果排除1例困难插管及7例胸腔粘连病人,最终94例病人研究数据被纳入分析。与C组[(14.8±2.8)min]及P组[(9.3±1.6)min]相比,M组[(6.8±1.3)min]病人胸腔开放后获得满意肺塌陷时间更短(均P<0.01);胸腔开放后1、5、10 min肺萎陷评分更高(均P<0.01)。M组病人各时间SpO_(2)、PaO_(2)、PaCO_(2)与P组相比差异无统计学意义(均P>0.05)。M组病人T_(2) MAP、心率较T_(1)、T_(3)短暂降低(均P<0.05)。三组病人无术中低氧血症发生;术中血管活性药物使用率、术后肺部并发症发生率、重症监护病房(ICU)转入率及术后住院天数组间比较均差异无统计学意义(均P>0.05)。结论改良预先OLV能更明显地加快胸腔镜手术双腔插管病人术侧肺萎陷,且对病人安全没有明显影响。 展开更多
关键词 单肺通气 胸腔镜手术 双腔管 肺萎陷 全身麻醉
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