Objective To investigate therapeutic effect of tri- amcinolone acetonide and pingyangmycin on lymphatic malformations in oral and maxillofacial regions. Methods 29 patients with lymphatic malformations in oral and max...Objective To investigate therapeutic effect of tri- amcinolone acetonide and pingyangmycin on lymphatic malformations in oral and maxillofacial regions. Methods 29 patients with lymphatic malformations in oral and maxillofacial regions were divided into two groups to re-展开更多
Introduction:Lymphatic malformations(LMs)are rare vascular anomalies predominantly affecting infants,which can be debilitating or life-threatening when complicated with intralesional bleeding or infection.Effective an...Introduction:Lymphatic malformations(LMs)are rare vascular anomalies predominantly affecting infants,which can be debilitating or life-threatening when complicated with intralesional bleeding or infection.Effective and safe management strategies are essential in such cases.Case presentation:We report a case series involving four Chinese neonates with life-threatening LMs,initially treated with oral sirolimus.All patients achieved rapid relief and sustained remission,using a lower sirolimus dosage than previously recommended.Furthermore,adverse events were rarely recorded during follow-up.Conclusion:Sirolimus can be considered a promising choice for neonates with intricate and life-threatening LMs.Initiation with a reduced sirolimus dose is advisable.展开更多
文摘Objective To investigate therapeutic effect of tri- amcinolone acetonide and pingyangmycin on lymphatic malformations in oral and maxillofacial regions. Methods 29 patients with lymphatic malformations in oral and maxillofacial regions were divided into two groups to re-
文摘Introduction:Lymphatic malformations(LMs)are rare vascular anomalies predominantly affecting infants,which can be debilitating or life-threatening when complicated with intralesional bleeding or infection.Effective and safe management strategies are essential in such cases.Case presentation:We report a case series involving four Chinese neonates with life-threatening LMs,initially treated with oral sirolimus.All patients achieved rapid relief and sustained remission,using a lower sirolimus dosage than previously recommended.Furthermore,adverse events were rarely recorded during follow-up.Conclusion:Sirolimus can be considered a promising choice for neonates with intricate and life-threatening LMs.Initiation with a reduced sirolimus dose is advisable.
