<strong>Introduction:</strong><span style="font-family:Verdana;"> The principal postoperative complication of mastectomies with</span><span style="font-family:Verdana;"&g...<strong>Introduction:</strong><span style="font-family:Verdana;"> The principal postoperative complication of mastectomies with</span><span style="font-family:Verdana;"> axillary dissection is the lymphocele that can last many months after surgery. The purpose of our study was to prevent its formation using the padding.</span><span style="font-family:""> </span><b><span style="font-family:Verdana;">Methods:</span></b><span style="font-family:Verdana;"> Sixty-one patients have been included in our study. The follow-up was 6 months. The patients were divided in two groups through a random draw (simple drainage and drainage associated with padding). All patients had a mastectomy with axillary dissection following the Madden technique. All quantities of lymphoceles during postoperative hospitalization and ambulatory care have been noted.</span><span style="font-family:""> </span><b><span style="font-family:Verdana;">Results:</span></b><span style="font-family:Verdana;"> Twenty-five patients had benefited f</span><span style="font-family:Verdana;">rom</span><span style="font-family:Verdana;"> the padding and 36 of a simple axillary drainage. Six months after the surgery, the patients benefitting from the padding had a quantity of lymphocele equal to half that of the control group (761.83 mL against 1373.60 mL;p = 0.01). During the postoperative hospitalization, the quantities were of 362.80 mL for the padding group versus 630.83 mL;p < 0.01. The hospitalization period was shorter for the padding patients (3.72 days vs 5.14 days;p = 0.01). However, pain was greater for the padding group upon 6 months (0.26 vs 0.10;p = 0.04). On another note, padding does not influence the duration of the surgery.</span><span style="font-family:""> </span><b><span style="font-family:Verdana;">Conclusion:</span></b><span style="font-family:Verdana;"> The production of postoperative lymphocele is heterogenous, varying from one patient to another. Nevertheless, the padding of the mastectomy compartment and of the axillary cavity allow</span><span style="font-family:Verdana;">s</span><span style="font-family:Verdana;"> a noticeable reduction of the produced quantity and of the hospitalization period at the expense of more pain.</span>展开更多
文摘<strong>Introduction:</strong><span style="font-family:Verdana;"> The principal postoperative complication of mastectomies with</span><span style="font-family:Verdana;"> axillary dissection is the lymphocele that can last many months after surgery. The purpose of our study was to prevent its formation using the padding.</span><span style="font-family:""> </span><b><span style="font-family:Verdana;">Methods:</span></b><span style="font-family:Verdana;"> Sixty-one patients have been included in our study. The follow-up was 6 months. The patients were divided in two groups through a random draw (simple drainage and drainage associated with padding). All patients had a mastectomy with axillary dissection following the Madden technique. All quantities of lymphoceles during postoperative hospitalization and ambulatory care have been noted.</span><span style="font-family:""> </span><b><span style="font-family:Verdana;">Results:</span></b><span style="font-family:Verdana;"> Twenty-five patients had benefited f</span><span style="font-family:Verdana;">rom</span><span style="font-family:Verdana;"> the padding and 36 of a simple axillary drainage. Six months after the surgery, the patients benefitting from the padding had a quantity of lymphocele equal to half that of the control group (761.83 mL against 1373.60 mL;p = 0.01). During the postoperative hospitalization, the quantities were of 362.80 mL for the padding group versus 630.83 mL;p < 0.01. The hospitalization period was shorter for the padding patients (3.72 days vs 5.14 days;p = 0.01). However, pain was greater for the padding group upon 6 months (0.26 vs 0.10;p = 0.04). On another note, padding does not influence the duration of the surgery.</span><span style="font-family:""> </span><b><span style="font-family:Verdana;">Conclusion:</span></b><span style="font-family:Verdana;"> The production of postoperative lymphocele is heterogenous, varying from one patient to another. Nevertheless, the padding of the mastectomy compartment and of the axillary cavity allow</span><span style="font-family:Verdana;">s</span><span style="font-family:Verdana;"> a noticeable reduction of the produced quantity and of the hospitalization period at the expense of more pain.</span>
文摘目的:探讨阿替普酶(rt-PA)静脉溶栓联合丁苯酞用于急性脑梗死(acute cerebral infarction,ACI)患者治疗中的临床效果。方法:以2022年1月—2023年6月瑞金市人民医院收治的ACI患者82例为研究对象,按随机数字表法分为对照组(脑梗死常规治疗+rt-PA静脉溶栓)、观察组(在对照组基础上联合应用丁苯酞),每组41例。观察对比两组神经功能缺损程度、生活自理能力、临床疗效、血清指标、不良反应发生率及生活质量评分。结果:治疗后两组美国国立卫生研究院卒中量表(national institutes of health stroke scale,NIHSS)评分较治疗前均降低,日常生活活动能力量表(activities of daily living,ADL)、健康调查简易量表(SF-36)评分较治疗前均升高,且观察组均优于对照组,差异均有统计学意义(P<0.05);观察组临床总有效率高于对照组,差异有统计学意义(P<0.05);两组不良反应发生率对比,差异无统计学意义(P>0.05);治疗后两组脑钠肽(brain natriuretic peptide,BNP)、同型半胱氨酸(homocysteine,Hcy)、C反应蛋白(C reactive protein,CRP)水平均较治疗前降低,且观察组均低于对照组,差异均有统计学意义(P<0.05)。结论:ACI患者应用rt-PA静脉溶栓联合丁苯酞治疗,临床效果确切,且安全性高,可促进神经功能恢复,改善预后。
