In the context of big data, many large-scale knowledge graphs have emerged to effectively organize the explosive growth of web data on the Internet. To select suitable knowledge graphs for use from many knowledge grap...In the context of big data, many large-scale knowledge graphs have emerged to effectively organize the explosive growth of web data on the Internet. To select suitable knowledge graphs for use from many knowledge graphs, quality assessment is particularly important. As an important thing of quality assessment, completeness assessment generally refers to the ratio of the current data volume to the total data volume.When evaluating the completeness of a knowledge graph, it is often necessary to refine the completeness dimension by setting different completeness metrics to produce more complete and understandable evaluation results for the knowledge graph.However, lack of awareness of requirements is the most problematic quality issue. In the actual evaluation process, the existing completeness metrics need to consider the actual application. Therefore, to accurately recommend suitable knowledge graphs to many users, it is particularly important to develop relevant measurement metrics and formulate measurement schemes for completeness. In this paper, we will first clarify the concept of completeness, establish each metric of completeness, and finally design a measurement proposal for the completeness of knowledge graphs.展开更多
At present,although knowledge graphs have been widely used in various fields such as recommendation systems,question and answer systems,and intelligent search,there are always quality problems such as knowledge omissi...At present,although knowledge graphs have been widely used in various fields such as recommendation systems,question and answer systems,and intelligent search,there are always quality problems such as knowledge omissions and errors.Quality assessment and control,as an important means to ensure the quality of knowledge,can make the applications based on knowledge graphs more complete and more accurate by reasonably assessing the knowledge graphs and fixing and improving the quality problems at the same time.Therefore,as an indispensable part of the knowledge graph construction process,the results of quality assessment and control determine the usefulness of the knowledge graph.Among them,the assessment and enhancement of completeness,as an important part of the assessment and control phase,determine whether the knowledge graph can fully reflect objective phenomena and reveal potential connections among entities.In this paper,we review specific techniques of completeness assessment and classify completeness assessment techniques in terms of closed world assumptions,open world assumptions,and partial completeness assumptions.The purpose of this paper is to further promote the development of knowledge graph quality control and to lay the foundation for subsequent research on the completeness assessment of knowledge graphs by reviewing and classifying completeness assessment techniques.展开更多
Gestational trophoblastic disease is an abnormal proliferation of trophoblastic tissue during pregnancy. It occurs in women of childbearing age, although a few cases have also been observed in post-menopausal women, a...Gestational trophoblastic disease is an abnormal proliferation of trophoblastic tissue during pregnancy. It occurs in women of childbearing age, although a few cases have also been observed in post-menopausal women, although it is extremely rare in the latter. Here we describe a rare case of complete hydatidiform mole in a 56-year-old female patient who presented with genital bleeding combined with nausea and vomiting and a gravid uterus 16 cm in height. The ultrasound findings and the increase in serum β-HCG to 182566.00 mIU/ml suggested a diagnosis of complete hydatidiform mole. Given the post-menopausal state and the future risk of post-molar gestational trophoblastic neoplasia, we opted for total hysterectomy without preservation of the adnexa via a transabdominal approach, followed by antimitotic treatment with methotrexate. The uterus measured 18.45 cm × 11.18 cm with intra cavitary vesicles. Microscopic examination showed chorionic villi of variable size and shape, most of which were dilated and oedematous, associated with trophoblastic cell proliferation and haemorrhage suggestive of complete benign hydatidiform mole. Follow-up showed a consistent decrease in serum β-HCG levels and no evidence of residual disease. A suspicion of gestational trophoblastic disease should be borne in mind when evaluating a patient with peri- or post-menopausal bleeding to avoid delay in diagnosis and treatment.展开更多
Background: The inadequacy in the completeness of the Laboratory Request Form (LRF) has been reported as one of the major sources of errors during the pre-analytical step of laboratory analysis. To prevent the occurre...Background: The inadequacy in the completeness of the Laboratory Request Form (LRF) has been reported as one of the major sources of errors during the pre-analytical step of laboratory analysis. To prevent the occurrence of such errors, this study aimed at assessing the level of completeness of LRFs. Methods: A retrospective analysis of laboratory request forms was conducted at the Clinical Biology Laboratory of the Kinshasa University Clinic, DR Congo, between November 2021 to May 2022. The LRFs were evaluated according to the completeness of all sections including administrative data of the patient, data of physician who ordered the test, relevant patient’s clinical data and data of the biological sample. Results: From a total of 2842 LRFs evaluated, none was fully completed with all required information. Particularly, patient’s clinical data including the medical history, provisional diagnosis and current treatment, were the most absent in 99% LRFs. However, two sections related to patient’s ID and prescribed test were informed in 100% LRFs. Conclusion: The results of this preanalytical audit can serve as an improvement opportunity focused on strengthening awareness about complete filling of LRF.展开更多
Collaborative coverage path planning(CCPP) refers to obtaining the shortest paths passing over all places except obstacles in a certain area or space. A multi-unmanned aerial vehicle(UAV) collaborative CCPP algorithm ...Collaborative coverage path planning(CCPP) refers to obtaining the shortest paths passing over all places except obstacles in a certain area or space. A multi-unmanned aerial vehicle(UAV) collaborative CCPP algorithm is proposed for the urban rescue search or military search in outdoor environment.Due to flexible control of small UAVs, it can be considered that all UAVs fly at the same altitude, that is, they perform search tasks on a two-dimensional plane. Based on the agents’ motion characteristics and environmental information, a mathematical model of CCPP problem is established. The minimum time for UAVs to complete the CCPP is the objective function, and complete coverage constraint, no-fly constraint, collision avoidance constraint, and communication constraint are considered. Four motion strategies and two communication strategies are designed. Then a distributed CCPP algorithm is designed based on hybrid strategies. Simulation results compared with patternbased genetic algorithm(PBGA) and random search method show that the proposed method has stronger real-time performance and better scalability and can complete the complete CCPP task more efficiently and stably.展开更多
Quality assurance in surgery has been one of the most important topics of debate among colorectal surgeons in the past decade.It has produced new surgical standards that led in part to the impressive oncological outco...Quality assurance in surgery has been one of the most important topics of debate among colorectal surgeons in the past decade.It has produced new surgical standards that led in part to the impressive oncological outcomes we see in many units today.Total mesorectal excision,complete mesocolic excision(CME),and the Japanese D3 lymphadenectomy are now benchmark techniques embraced by many surgeons and widely recommended by surgical societies.However,there are still ongoing discrepancies in outcomes largely based on surgeon performance.This is one of the main reasons why many countries have shifted colorectal cancer surgery only to high volume centers.Defining markers of surgical quality is thus a perquisite to ensure that standards and oncological outcomes are met at an institutional level.With the evolution of CME surgery,various quality markers have been described,mostly based on measurements on the surgical specimen and lymph node yield,while others have proposed radiological markers(i.e.arterial stumps)measured on postoperative scans as part of the routine cancer follow-up.There is no ideal marker;however,taken together and assembled into a new score or set of criteria may become a future point of reference for reporting outcomes of colorectal cancer surgery in research studies and defining subspecialization requirements both at an individual and hospital level.展开更多
The problem of high-precision indoor positioning in the 5G era has attracted more and more attention.A fingerprint location method based on matrix completion(MC-FPL)is proposed for 5G ultradense networks to overcome t...The problem of high-precision indoor positioning in the 5G era has attracted more and more attention.A fingerprint location method based on matrix completion(MC-FPL)is proposed for 5G ultradense networks to overcome the high costs of traditional fingerprint database construction and matching algorithms.First,a partial fingerprint database constructed and the accelerated proximal gradient algorithm is used to fill the partial fingerprint database to construct a full fingerprint database.Second,a fingerprint database division method based on the strongest received signal strength indicator is proposed,which divides the original fingerprint database into several sub-fingerprint databases.Finally,a classification weighted K-nearest neighbor fingerprint matching algorithm is proposed.The estimated coordinates of the point to be located can be obtained by fingerprint matching in a sub-fingerprint database.The simulation results show that the MC-FPL algorithm can reduce the complexity of database construction and fingerprint matching and has higher positioning accuracy compared with the traditional fingerprint algorithm.展开更多
BACKGROUND Function-preserving pancreatectomy can improve the long-term quality of life of patients with benign or low-grade malignant tumors,such as intraductal papillary mucinous neoplasms(IPMNs)and mucinous cystic ...BACKGROUND Function-preserving pancreatectomy can improve the long-term quality of life of patients with benign or low-grade malignant tumors,such as intraductal papillary mucinous neoplasms(IPMNs)and mucinous cystic neoplasms.However,there is limited literature on laparoscopic spleen-preserving total pancreatectomy(LSpTP)due to technical difficulties.CASE SUMMARY Patient 1 was a 51-year-old male diagnosed with IPMN based on preoperative imaging,showing solid nodules in the pancreatic head and diffuse dilation of the main pancreatic duct with atrophy of the distal pancreas.We performed L-SpTP with preservation of the splenic vessels,and the postoperative pathology report revealed IPMN with invasive carcinoma.Patient 2 was a 60-year-old male with multiple cystic lesions in the pancreatic head and body.L-SpTP was performed,and intraoperatively,the splenic vein was injured and required ligation.Postoperative pathology revealed a mucinous cystic tumor of the pancreas with low-grade dysplasia.Both patients were discharged on postoperative day 7,and there were no major complications during the perioperative period.CONCLUSION We believe that L-SpTP is a safe and feasible treatment for low-grade malignant pancreatic tumors,but more case studies are needed to evaluate its safety,efficacy,and long-term outcomes.展开更多
Current methods for predicting missing values in datasets often rely on simplistic approaches such as taking median value of attributes, limiting their applicability. Real-world observations can be diverse, taking sto...Current methods for predicting missing values in datasets often rely on simplistic approaches such as taking median value of attributes, limiting their applicability. Real-world observations can be diverse, taking stock price as example, ranging from prices post-IPO to values before a company’s collapse, or instances where certain data points are missing due to stock suspension. In this paper, we propose a novel approach using Nonlinear Matrix Completion (NIMC) and Deep Matrix Completion (DIMC) to predict associations, and conduct experiment on financial data between dates and stocks. Our method leverages various types of stock observations to capture latent factors explaining the observed date-stock associations. Notably, our approach is nonlinear, making it suitable for datasets with nonlinear structures, such as the Russell 3000. Unlike traditional methods that may suffer from information loss, NIMC and DIMC maintain nearly complete information, especially in high-dimensional parameters. We compared our approach with state-of-the-art linear methods, including Inductive Matrix Completion, Nonlinear Inductive Matrix Completion, and Deep Inductive Matrix Completion. Our findings show that the nonlinear matrix completion method is particularly effective for handling nonlinear structured data, as exemplified by the Russell 3000. Additionally, we validate the information loss of the three methods across different dimensionalities.展开更多
The scope of this study is to analyze some aspects of the Algerian earthquake catalogue between 1980 and 2009.Seismicity analysis is based on reliable compilation of earthquake catalogs obtained from different agencie...The scope of this study is to analyze some aspects of the Algerian earthquake catalogue between 1980 and 2009.Seismicity analysis is based on reliable compilation of earthquake catalogs obtained from different agencies.All intensities and magnitudes were converted to Ms magnitude using appropriate relationships.Dependent events were removed using adapted time and space windows.In addition,the completeness of the catalogue as a function of magnitude was determined from the standard deviation of occurrence rate plots,using the Stepp’s methodology.The remaining 2,016 independent earthquakes with Ms 2.2 were used to obtain various parameters(b-value,z-value)to characterize the temporal and spatial seismic activity for the entire northern part of Algeria.Finally,the obtained results are discussed to explain parameters variability.展开更多
BACKGROUND The prognosis for patients with advanced metastatic cervix cancer(MCC)is poor,and this disease continues to pose a considerable therapeutic challenge.Despite the administration of first-line regimens consis...BACKGROUND The prognosis for patients with advanced metastatic cervix cancer(MCC)is poor,and this disease continues to pose a considerable therapeutic challenge.Despite the administration of first-line regimens consisting of cisplatin,paclitaxel,and bevacizumab,survival rates for patients with metastasis remain poor.The emergence of bispecific antibodies(BsAbs)offers a novel treatment option for patients diagnosed with MCC.CASE SUMMARY In this report,we present a patient with MCC who was treated with cadonilimab monotherapy at a dose of 6 mg/kg every two weeks after chemotherapy was proven to be intolerable.The patient exhibited a sustained complete response for a duration of 6 months,demonstrating an optimistic outlook.CONCLUSION This case illustrates the considerable efficacy of cadonilimab for treating advanced MCC.Therefore,BsAb therapy is a promising strategy for effectively treating patients with advanced MCC and should be considered as an option when patients are intolerant to standard chemotherapy.展开更多
We use a lot of devices in our daily life to communicate with others. In this modern world, people use email, Facebook, Twitter, and many other social network sites for exchanging information. People lose their valuab...We use a lot of devices in our daily life to communicate with others. In this modern world, people use email, Facebook, Twitter, and many other social network sites for exchanging information. People lose their valuable time misspelling and retyping, and some people are not happy to type large sentences because they face unnecessary words or grammatical issues. So, for this reason, word predictive systems help to exchange textual information more quickly, easier, and comfortably for all people. These systems predict the next most probable words and give users to choose of the needed word from these suggested words. Word prediction can help the writer by predicting the next word and helping complete the sentence correctly. This research aims to forecast the most suitable next word to complete a sentence for any given context. In this research, we have worked on the Bangla language. We have presented a process that can expect the next maximum probable and proper words and suggest a complete sentence using predicted words. In this research, GRU-based RNN has been used on the N-gram dataset to develop the proposed model. We collected a large dataset using multiple sources in the Bangla language and also compared it to the other approaches that have been used such as LSTM, and Naive Bayes. But this suggested approach provides excellent exactness than others. Here, the Unigram model provides 88.22%, Bi-gram model is 99.24%, Tri-gram model is 97.69%, and 4-gram and 5-gram models provide 99.43% and 99.78% on average accurateness. We think that our proposed method profound impression on Bangla search engines.展开更多
Aquatic medicine knowledge graph is an effective means to realize intelligent aquaculture.Graph completion technology is key to improving the quality of knowledge graph construction.However,the difficulty of semantic ...Aquatic medicine knowledge graph is an effective means to realize intelligent aquaculture.Graph completion technology is key to improving the quality of knowledge graph construction.However,the difficulty of semantic discrimination among similar entities and inconspicuous semantic features result in low accuracy when completing aquatic medicine knowledge graph with complex relationships.In this study,an aquatic medicine knowledge graph completion method(TransH+HConvAM)is proposed.Firstly,TransH is applied to split the vector plane between entities and relations,ameliorating the poor completion effect caused by low semantic resolution of entities.Then,hybrid convolution is introduced to obtain the global interaction of triples based on the complete interaction between head/tail entities and relations,which improves the semantic features of triples and enhances the completion effect of complex relationships in the graph.Experiments are conducted to verify the performance of the proposed method.The MR,MRR and Hit@10 of the TransH+HConvAM are found to be 674,0.339,and 0.361,respectively.This study shows that the model effectively overcomes the poor completion effect of complex relationships and improves the construction quality of the aquatic medicine knowledge graph,providing technical support for intelligent aquaculture.展开更多
As a prerequisite and a guarantee for safe and efficient natural gas hydrates(NGHs)exploitation,it is imperative to effectively determine the mechanical properties of NGHs reservoirs and clarify the law of the change ...As a prerequisite and a guarantee for safe and efficient natural gas hydrates(NGHs)exploitation,it is imperative to effectively determine the mechanical properties of NGHs reservoirs and clarify the law of the change in the mechanical properties with the dissociation of NGHs during NGHs production tests by depressurization.Based on the development of Japan’s two offshore NGHs production tests in vertical wells,this study innovatively proposed a new subsea communication technology-accurate directional connection using a wet-mate connector.This helps to overcome the technical barrier to the communication between the upper and lower completion of offshore wells.Using this new communication technology,this study explored and designed a mechanical monitoring scheme for lower completion(sand screens).This scheme can be used to monitor the tensile stress and radial compressive stress of sand screens caused by NGHs reservoirs in real time,thus promoting the technical development for the rapid assessment and real-time feedback of the in-situ mechanical response of NGHs reservoirs during offshore NGHs production tests by depressurization.展开更多
To meet the requirements of marine natural gas hydrate exploitation,it is necessary to improve the penetration of completion sand control string in the large curvature borehole.In this study,large curvature test wells...To meet the requirements of marine natural gas hydrate exploitation,it is necessary to improve the penetration of completion sand control string in the large curvature borehole.In this study,large curvature test wells were selected to carry out the running test of sand control string with pre-packed screen.Meanwhile,the running simulation was performed by using the Landmark software.The results show that the sand control packer and screen can be run smoothly in the wellbore with a dogleg angle of more than 20°/30 m and keep the structure stable.Additionally,the comprehensive friction coefficient is 0.4,under which and the simulation shows that the sand control string for hydrate exploitation can be run smoothly.These findings have important guiding significance for running the completion sand control string in natural gas hydrate exploitation.展开更多
基金supported by the National Key Laboratory for Comp lex Systems Simulation Foundation (6142006190301)。
文摘In the context of big data, many large-scale knowledge graphs have emerged to effectively organize the explosive growth of web data on the Internet. To select suitable knowledge graphs for use from many knowledge graphs, quality assessment is particularly important. As an important thing of quality assessment, completeness assessment generally refers to the ratio of the current data volume to the total data volume.When evaluating the completeness of a knowledge graph, it is often necessary to refine the completeness dimension by setting different completeness metrics to produce more complete and understandable evaluation results for the knowledge graph.However, lack of awareness of requirements is the most problematic quality issue. In the actual evaluation process, the existing completeness metrics need to consider the actual application. Therefore, to accurately recommend suitable knowledge graphs to many users, it is particularly important to develop relevant measurement metrics and formulate measurement schemes for completeness. In this paper, we will first clarify the concept of completeness, establish each metric of completeness, and finally design a measurement proposal for the completeness of knowledge graphs.
基金supported by the National Key Laboratory for Complex Systems Simulation Foundation(6142006190301)。
文摘At present,although knowledge graphs have been widely used in various fields such as recommendation systems,question and answer systems,and intelligent search,there are always quality problems such as knowledge omissions and errors.Quality assessment and control,as an important means to ensure the quality of knowledge,can make the applications based on knowledge graphs more complete and more accurate by reasonably assessing the knowledge graphs and fixing and improving the quality problems at the same time.Therefore,as an indispensable part of the knowledge graph construction process,the results of quality assessment and control determine the usefulness of the knowledge graph.Among them,the assessment and enhancement of completeness,as an important part of the assessment and control phase,determine whether the knowledge graph can fully reflect objective phenomena and reveal potential connections among entities.In this paper,we review specific techniques of completeness assessment and classify completeness assessment techniques in terms of closed world assumptions,open world assumptions,and partial completeness assumptions.The purpose of this paper is to further promote the development of knowledge graph quality control and to lay the foundation for subsequent research on the completeness assessment of knowledge graphs by reviewing and classifying completeness assessment techniques.
文摘Gestational trophoblastic disease is an abnormal proliferation of trophoblastic tissue during pregnancy. It occurs in women of childbearing age, although a few cases have also been observed in post-menopausal women, although it is extremely rare in the latter. Here we describe a rare case of complete hydatidiform mole in a 56-year-old female patient who presented with genital bleeding combined with nausea and vomiting and a gravid uterus 16 cm in height. The ultrasound findings and the increase in serum β-HCG to 182566.00 mIU/ml suggested a diagnosis of complete hydatidiform mole. Given the post-menopausal state and the future risk of post-molar gestational trophoblastic neoplasia, we opted for total hysterectomy without preservation of the adnexa via a transabdominal approach, followed by antimitotic treatment with methotrexate. The uterus measured 18.45 cm × 11.18 cm with intra cavitary vesicles. Microscopic examination showed chorionic villi of variable size and shape, most of which were dilated and oedematous, associated with trophoblastic cell proliferation and haemorrhage suggestive of complete benign hydatidiform mole. Follow-up showed a consistent decrease in serum β-HCG levels and no evidence of residual disease. A suspicion of gestational trophoblastic disease should be borne in mind when evaluating a patient with peri- or post-menopausal bleeding to avoid delay in diagnosis and treatment.
文摘Background: The inadequacy in the completeness of the Laboratory Request Form (LRF) has been reported as one of the major sources of errors during the pre-analytical step of laboratory analysis. To prevent the occurrence of such errors, this study aimed at assessing the level of completeness of LRFs. Methods: A retrospective analysis of laboratory request forms was conducted at the Clinical Biology Laboratory of the Kinshasa University Clinic, DR Congo, between November 2021 to May 2022. The LRFs were evaluated according to the completeness of all sections including administrative data of the patient, data of physician who ordered the test, relevant patient’s clinical data and data of the biological sample. Results: From a total of 2842 LRFs evaluated, none was fully completed with all required information. Particularly, patient’s clinical data including the medical history, provisional diagnosis and current treatment, were the most absent in 99% LRFs. However, two sections related to patient’s ID and prescribed test were informed in 100% LRFs. Conclusion: The results of this preanalytical audit can serve as an improvement opportunity focused on strengthening awareness about complete filling of LRF.
基金supported by the National Natural Science Foundation of China (61903036, 61822304)Shanghai Municipal Science and Technology Major Project (2021SHZDZX0100)。
文摘Collaborative coverage path planning(CCPP) refers to obtaining the shortest paths passing over all places except obstacles in a certain area or space. A multi-unmanned aerial vehicle(UAV) collaborative CCPP algorithm is proposed for the urban rescue search or military search in outdoor environment.Due to flexible control of small UAVs, it can be considered that all UAVs fly at the same altitude, that is, they perform search tasks on a two-dimensional plane. Based on the agents’ motion characteristics and environmental information, a mathematical model of CCPP problem is established. The minimum time for UAVs to complete the CCPP is the objective function, and complete coverage constraint, no-fly constraint, collision avoidance constraint, and communication constraint are considered. Four motion strategies and two communication strategies are designed. Then a distributed CCPP algorithm is designed based on hybrid strategies. Simulation results compared with patternbased genetic algorithm(PBGA) and random search method show that the proposed method has stronger real-time performance and better scalability and can complete the complete CCPP task more efficiently and stably.
文摘Quality assurance in surgery has been one of the most important topics of debate among colorectal surgeons in the past decade.It has produced new surgical standards that led in part to the impressive oncological outcomes we see in many units today.Total mesorectal excision,complete mesocolic excision(CME),and the Japanese D3 lymphadenectomy are now benchmark techniques embraced by many surgeons and widely recommended by surgical societies.However,there are still ongoing discrepancies in outcomes largely based on surgeon performance.This is one of the main reasons why many countries have shifted colorectal cancer surgery only to high volume centers.Defining markers of surgical quality is thus a perquisite to ensure that standards and oncological outcomes are met at an institutional level.With the evolution of CME surgery,various quality markers have been described,mostly based on measurements on the surgical specimen and lymph node yield,while others have proposed radiological markers(i.e.arterial stumps)measured on postoperative scans as part of the routine cancer follow-up.There is no ideal marker;however,taken together and assembled into a new score or set of criteria may become a future point of reference for reporting outcomes of colorectal cancer surgery in research studies and defining subspecialization requirements both at an individual and hospital level.
基金supported in part by Sub Project of National Key Research and Development plan in 2020.NO.2020YFC1511704Beijing Information Science and Technology University.NO.2020KYNH212,NO.2021CGZH302+1 种基金Beijing Science and Technology Project(Grant No.Z211100004421009)in part by the National Natural Science Foundation of China(Grant No.61971048)。
文摘The problem of high-precision indoor positioning in the 5G era has attracted more and more attention.A fingerprint location method based on matrix completion(MC-FPL)is proposed for 5G ultradense networks to overcome the high costs of traditional fingerprint database construction and matching algorithms.First,a partial fingerprint database constructed and the accelerated proximal gradient algorithm is used to fill the partial fingerprint database to construct a full fingerprint database.Second,a fingerprint database division method based on the strongest received signal strength indicator is proposed,which divides the original fingerprint database into several sub-fingerprint databases.Finally,a classification weighted K-nearest neighbor fingerprint matching algorithm is proposed.The estimated coordinates of the point to be located can be obtained by fingerprint matching in a sub-fingerprint database.The simulation results show that the MC-FPL algorithm can reduce the complexity of database construction and fingerprint matching and has higher positioning accuracy compared with the traditional fingerprint algorithm.
基金Supported by National High Level Hospital Clinical Research Funding,No.2022-PUMCH-B-003National Multidisciplinary Cooperative Diagnosis and Treatment Capacity Building Project for Major Diseases。
文摘BACKGROUND Function-preserving pancreatectomy can improve the long-term quality of life of patients with benign or low-grade malignant tumors,such as intraductal papillary mucinous neoplasms(IPMNs)and mucinous cystic neoplasms.However,there is limited literature on laparoscopic spleen-preserving total pancreatectomy(LSpTP)due to technical difficulties.CASE SUMMARY Patient 1 was a 51-year-old male diagnosed with IPMN based on preoperative imaging,showing solid nodules in the pancreatic head and diffuse dilation of the main pancreatic duct with atrophy of the distal pancreas.We performed L-SpTP with preservation of the splenic vessels,and the postoperative pathology report revealed IPMN with invasive carcinoma.Patient 2 was a 60-year-old male with multiple cystic lesions in the pancreatic head and body.L-SpTP was performed,and intraoperatively,the splenic vein was injured and required ligation.Postoperative pathology revealed a mucinous cystic tumor of the pancreas with low-grade dysplasia.Both patients were discharged on postoperative day 7,and there were no major complications during the perioperative period.CONCLUSION We believe that L-SpTP is a safe and feasible treatment for low-grade malignant pancreatic tumors,but more case studies are needed to evaluate its safety,efficacy,and long-term outcomes.
文摘Current methods for predicting missing values in datasets often rely on simplistic approaches such as taking median value of attributes, limiting their applicability. Real-world observations can be diverse, taking stock price as example, ranging from prices post-IPO to values before a company’s collapse, or instances where certain data points are missing due to stock suspension. In this paper, we propose a novel approach using Nonlinear Matrix Completion (NIMC) and Deep Matrix Completion (DIMC) to predict associations, and conduct experiment on financial data between dates and stocks. Our method leverages various types of stock observations to capture latent factors explaining the observed date-stock associations. Notably, our approach is nonlinear, making it suitable for datasets with nonlinear structures, such as the Russell 3000. Unlike traditional methods that may suffer from information loss, NIMC and DIMC maintain nearly complete information, especially in high-dimensional parameters. We compared our approach with state-of-the-art linear methods, including Inductive Matrix Completion, Nonlinear Inductive Matrix Completion, and Deep Inductive Matrix Completion. Our findings show that the nonlinear matrix completion method is particularly effective for handling nonlinear structured data, as exemplified by the Russell 3000. Additionally, we validate the information loss of the three methods across different dimensionalities.
文摘The scope of this study is to analyze some aspects of the Algerian earthquake catalogue between 1980 and 2009.Seismicity analysis is based on reliable compilation of earthquake catalogs obtained from different agencies.All intensities and magnitudes were converted to Ms magnitude using appropriate relationships.Dependent events were removed using adapted time and space windows.In addition,the completeness of the catalogue as a function of magnitude was determined from the standard deviation of occurrence rate plots,using the Stepp’s methodology.The remaining 2,016 independent earthquakes with Ms 2.2 were used to obtain various parameters(b-value,z-value)to characterize the temporal and spatial seismic activity for the entire northern part of Algeria.Finally,the obtained results are discussed to explain parameters variability.
文摘BACKGROUND The prognosis for patients with advanced metastatic cervix cancer(MCC)is poor,and this disease continues to pose a considerable therapeutic challenge.Despite the administration of first-line regimens consisting of cisplatin,paclitaxel,and bevacizumab,survival rates for patients with metastasis remain poor.The emergence of bispecific antibodies(BsAbs)offers a novel treatment option for patients diagnosed with MCC.CASE SUMMARY In this report,we present a patient with MCC who was treated with cadonilimab monotherapy at a dose of 6 mg/kg every two weeks after chemotherapy was proven to be intolerable.The patient exhibited a sustained complete response for a duration of 6 months,demonstrating an optimistic outlook.CONCLUSION This case illustrates the considerable efficacy of cadonilimab for treating advanced MCC.Therefore,BsAb therapy is a promising strategy for effectively treating patients with advanced MCC and should be considered as an option when patients are intolerant to standard chemotherapy.
文摘We use a lot of devices in our daily life to communicate with others. In this modern world, people use email, Facebook, Twitter, and many other social network sites for exchanging information. People lose their valuable time misspelling and retyping, and some people are not happy to type large sentences because they face unnecessary words or grammatical issues. So, for this reason, word predictive systems help to exchange textual information more quickly, easier, and comfortably for all people. These systems predict the next most probable words and give users to choose of the needed word from these suggested words. Word prediction can help the writer by predicting the next word and helping complete the sentence correctly. This research aims to forecast the most suitable next word to complete a sentence for any given context. In this research, we have worked on the Bangla language. We have presented a process that can expect the next maximum probable and proper words and suggest a complete sentence using predicted words. In this research, GRU-based RNN has been used on the N-gram dataset to develop the proposed model. We collected a large dataset using multiple sources in the Bangla language and also compared it to the other approaches that have been used such as LSTM, and Naive Bayes. But this suggested approach provides excellent exactness than others. Here, the Unigram model provides 88.22%, Bi-gram model is 99.24%, Tri-gram model is 97.69%, and 4-gram and 5-gram models provide 99.43% and 99.78% on average accurateness. We think that our proposed method profound impression on Bangla search engines.
基金supported by the Key Laboratory of Environment Controlled Aquaculture(Dalian Ocean University)Ministry of Education(No.2021-MOEKLECA-KF-05)the National Natural Science Foundation of China Youth Science(No.61802046)。
文摘Aquatic medicine knowledge graph is an effective means to realize intelligent aquaculture.Graph completion technology is key to improving the quality of knowledge graph construction.However,the difficulty of semantic discrimination among similar entities and inconspicuous semantic features result in low accuracy when completing aquatic medicine knowledge graph with complex relationships.In this study,an aquatic medicine knowledge graph completion method(TransH+HConvAM)is proposed.Firstly,TransH is applied to split the vector plane between entities and relations,ameliorating the poor completion effect caused by low semantic resolution of entities.Then,hybrid convolution is introduced to obtain the global interaction of triples based on the complete interaction between head/tail entities and relations,which improves the semantic features of triples and enhances the completion effect of complex relationships in the graph.Experiments are conducted to verify the performance of the proposed method.The MR,MRR and Hit@10 of the TransH+HConvAM are found to be 674,0.339,and 0.361,respectively.This study shows that the model effectively overcomes the poor completion effect of complex relationships and improves the construction quality of the aquatic medicine knowledge graph,providing technical support for intelligent aquaculture.
基金supported jointly by the major projects of Basic and Applied Basic Research in Guangdong Province“Key Basic Theory Research for Natural Gas Hydrate Trial Production in Shenhu Pilot Test Area”(2020B0301030003)the project from Southern Marine Science&Engineering Guangdong Laboratory in Guangzhou City“Research on New Closed Circulation Drilling Technology without Riser”(GML2019ZD0501).
文摘As a prerequisite and a guarantee for safe and efficient natural gas hydrates(NGHs)exploitation,it is imperative to effectively determine the mechanical properties of NGHs reservoirs and clarify the law of the change in the mechanical properties with the dissociation of NGHs during NGHs production tests by depressurization.Based on the development of Japan’s two offshore NGHs production tests in vertical wells,this study innovatively proposed a new subsea communication technology-accurate directional connection using a wet-mate connector.This helps to overcome the technical barrier to the communication between the upper and lower completion of offshore wells.Using this new communication technology,this study explored and designed a mechanical monitoring scheme for lower completion(sand screens).This scheme can be used to monitor the tensile stress and radial compressive stress of sand screens caused by NGHs reservoirs in real time,thus promoting the technical development for the rapid assessment and real-time feedback of the in-situ mechanical response of NGHs reservoirs during offshore NGHs production tests by depressurization.
基金supported jointly by one of the major projects of Basic and Applied Basic Research in Guangdong Province“Key Basic Theory Research for Natural Gas Hydrate Trial Production in Shenhu Pilot Test Area”(2020B0301030003)the project from Southern Marine Science&Engineering Guangdong Laboratory Guangzhou City“Research on New Closed Circulation Drilling Technology without Riser”(GML2019ZD0501)the special project for hydrate from China Geological Survey“Trial Production Implementation for Natural Gas Hydrate in Shenhu Pilot Test Area”(DD20190226)。
文摘To meet the requirements of marine natural gas hydrate exploitation,it is necessary to improve the penetration of completion sand control string in the large curvature borehole.In this study,large curvature test wells were selected to carry out the running test of sand control string with pre-packed screen.Meanwhile,the running simulation was performed by using the Landmark software.The results show that the sand control packer and screen can be run smoothly in the wellbore with a dogleg angle of more than 20°/30 m and keep the structure stable.Additionally,the comprehensive friction coefficient is 0.4,under which and the simulation shows that the sand control string for hydrate exploitation can be run smoothly.These findings have important guiding significance for running the completion sand control string in natural gas hydrate exploitation.