Factors and expectations influencing concussion disclosure within NCAA DivisionⅠathletes:A mixed methodological approach

Background:Participation in sports is associated with many benefits to all aspects of health;however,it also comes with the risk of injury,particularly concussions.Self-disclosure and care seeking following a concussion are especially important because of the lack of outwardly visible signs and/or symptoms.Although recent research has explored factors affecting concussion disclosure,use of isolated methodologies limits the ability to contextualize how disclosure or nondisclosure occurs.Therefore,the purpose of this study was to describe the factors and expectations of National Collegiate Athletic Association(NCAA)athletes that may influence concussion disclosure.Methods:This mixed-methods convergent parallel research study included 25 NCAA Division I athletes representing 13 sports,all of whom completed a concussion-education session with pre-/post-test surveys and a semistructured interview.Eligible athletes were at least 18 years old and on an NCAA roster.The surveys focused on previous concussion-related disclosure behaviors,knowledge,attitudes,beliefs,norms,and intentions about disclosing concussion.Interviews focused on the athletes’experiences related to concussion disclosure.Survey data were analyzed using descriptive statistics and Mann-Whitney U tests.Interviews were analyzed using a Consensual Qualitative Research tradition.Results:Participants had good concussion knowledge(median=46.0),positive attitudes(median=38.0),strong beliefs(median=13.0),and strong intentions to disclose concussion symptoms(median=7.0).None of the constructs differed by participants’gender.Although quantitative findings were mostly positive,interview data highlighted factors that may explain why some participants are successful in disclosing concussions and why others may find disclosure difficult.Educational efforts,sport culture,and medical professional presence were the primary facilitators discussed by participants.Stigma,pressure,and a lack of team support were perceived as disclosure barriers.Conclusion:The context in which concussion disclosure occurs or does not occur is vital to the success of educational interventions.Interventions must prioritize stakeholder-and team-based perspectives on concussion to establish a network supportive to disclosure.

Utilization of online systems to promote youth participation in research:A methodological study

BACKGROUND Online surveys can align with youth’s increased use of the internet and can be a mechanism for expanding youth participation in research.This is particularly important during the coronavirus disease 2019(COVID-19)pandemic,when inperson interactions are limited.However,the advantages and drawbacks of online systems used for research need to be carefully considered before utilizing such methodologies.AIM To describe and discuss the strengths and limitations of an online system developed to recruit adolescent girls for a sexual health research study and conduct a three-month follow up survey.METHODS This methodology paper examines the use of an online system to recruit and follow participants three months after their medical visit to evaluate a mobile sexual and reproductive health application,Health-E You/Salud iTuTM,for adolescent girls attending school-based health centers(SBHCs)across the United States.SBHC staff gave adolescent girls a web link to an online eligibility and consent survey.Participants were then asked to complete two online surveys(baseline and 3-month follow-up).Surveys,reminders,and incentives to complete them were distributed through short message service(SMS)text messages.Upon completing each survey,participants were also sent an email with a link to an electronic gift card as a thank-you for their participation.Barriers to implementing this system were discussed with clinicians and staff at each participating SBHC.RESULTS This online recruitment and retention system enabled participant recruitment at 26 different SBHCs in seven states across the United States.Between September 2021 and June 2022,415 adolescent girls were screened using the Qualtrics online survey platform,and 182 were eligible to participate.Of those eligible,78.0%(n=142)completed the baseline survey.Participants were racially,geographically,and linguistically diverse.Most of the participants(89.4%)were non-White,and 40.8%spoke Spanish.A total of 62.0%(n=88)completed the 3-month follow-up survey.Limitations of this system included reliance on internet access(via Wi-Fi or cell service),which was not universally available or reliable.In addition,an individual unrelated to the study obtained the survey link,filled out multiple surveys,and received multiple gift cards before the research team discovered and stopped this activity.As a result,additional security protocols were instituted.CONCLUSION Online systems for health research can increase the reach and diversity of study participants,reduce costs for research personnel time and travel,allow for continued study operation when in-person visits are limited(such as during the COVID-19 pandemic),and connect youth with research using technology.However,there are challenges and limitations to online systems,which include limited internet access,intermittent internet connection,data security concerns,and the potential for fraudulent users.These challenges should be considered prior to using online systems for research.

On the Options of EFL Methodological Approaches

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Methodological quality(risk of bias) assessment tools for primary and secondary medical studies: What are they and which is better?

Methodological quality(risk of bias)assessment is an important step before study initiation usage.Therefore,accurately judging study type is the first priority,and the choosing proper tool is also important.In this review,we introduced methodological quality assessment tools for randomized controlled trial(including individual and cluster),animal study,non-randomized interventional studies(including follow-up study,controlled before-and-after study,before-after/pre-post study,uncontrolled longitudinal study,interrupted time series study),cohort study,case-control study,cross-sectional study(including analytical and descriptive),observational case series and case reports,comparative effectiveness research,diagnostic study,health economic evaluation,prediction study(including predictor finding study,prediction model impact study,prognostic prediction model study),qualitative study,outcome measurement instruments(including patient-reported outcome measure development,content validity,structural validity,internal consistency,cross-cultural validity/measurement invariance,reliability,measurement error,criterion validity,hypotheses testing for construct validity,and responsiveness),systematic review and meta-analysis,and clinical practice guideline.The readers of our review can distinguish the types of medical studies and choose appropriate tools.In one word,comprehensively mastering relevant knowledge and implementing more practices are basic requirements for correctly assessing the methodological quality.

Effectiveness of probiotics in irritable bowel syndrome: methodological quality of meta-analyses and systematic reviews

Objective: This study assessed the methodological quality of systematic reviews/meta-analysis of the effectiveness of probiotics against irritable bowel syndrome (IBS) using the accepted methodological quality assessment scale AMSTAR and explored the factors that influenced the quality of methodology. It was designed to provide a reference for future research and systematic reviews/metaanalysis. Methods: The methodological quality of existing systematic reviews/meta-analysis was evaluated using the AMSTAR scale. Influencing factors of methodological quality were statistically analyzed using RevMan 5.3 software. The included systematic reviews/metaanalysis must include the following characteristics:(1) methods using systematic evaluation/meta-analysis,(2) probiotic intervention, and (3) language limitation to Chinese and English. Results: The AMSTAR score was 5-9 (7.42 ± 1.22), and the quality is above average. The factors affecting the methodological quality are the number of authors and whether they cooperate with the institution. Conclusions: Studies have shown that current systematic reviews/meta-analysis of the effectiveness of probiotics on IBS does not fully comply with methodological quality standards, and therefore the methodological quality of research in this area needs to be strengthened. To better clarify how probiotics affect IBS, future systematic reviews and meta-analyses should not only follow methodological quality standards but also include more effective outcome measures, and they should focus more on the discussion of research results. We look forward to the development of higher-quality randomized controlled trials in the future.

Current Issues in Software Re-Usability: A Critical Review of the Methodological &Legal Issues

The main objective of this research is to discuss the current legal and methodological issues in the field of software Re-Usability. Though there are enormous online forums discussing such issues via Q&A but this paper is an attempt to raise the awareness about the legal issues, which a software engineer may trap into. The paper discussed the current issues with software reusability within the legal and methodological context. This paper applied an extensive literature review to critically appraise the past studies to come to a collective conclusion. Prior to discussing the issues, the benefits of reuse were mentioned, including the saving of time and cost for users. But legally the reuse of software assets creates complexities for the user in relation to meeting all the licensing requirements and dealing with the liability in case of a breach. Methodologically, there are major barriers to reused software when it comes to technical competence and managerial issues such as a lack of resources. Even when reusing software to save time, and leverage off the specialization of other authors, the end-user must also have the technical expertise to search, adapt and merge these reusable assets into the larger software infrastructure. The review ultimately shows the high barriers still remain to software reuse which could mean that smaller developers and businesses will still be reluctant to fully utilize open-source components to the best advantage.

Methodological quality assessment of meta-analyses of cognitive interventions among Alzheimer's disease

Aims:The current study is designed to assess the methodological quality of the meta-analyses of cognitive interventions among Alzheimer's disease,and to investigate the compliance with 16 AMSTAR 2 items.Method:We searched Web of Scie nce,Sino med,PubMed,Embase,and Cochra ne Library from 2016 to 2021,to get the meta-a nalyses of cog nitive in terve nti ons in Alzheimer's disease.The AMSTAR 2 was used to assess the methodological quality.Furthermore,we also explored the complia nce with AMSTAR.Resul ts:We in cluded 9 studies in our research.Of them,6 articles were rated as"extremely low",2 articles as"low"and 1 article as"high".Furthermore,the reporting rates for 16 AMSTAR 2 items ranged from 22.22%to 100%.Conclusion:The methodological quality of meta-analyses of cognitive interventions in Alzheimer's disease is not ideal,and there is still room for improvement.Future studies are supposed to explore the releva nt factors that possibly in flue nce the methodological quality.

Methodological quality evaluation of systematic reviews of music therapy for Alzheimer’s disease in the recent five years

Aims:This study aims to investigate the methodological quality of the systematic reviews of music therapy for Alzheimer’s Disease in the past five years,and to explore their compliance with each AMSTAR(A Measure Tool to Assess Systematic Reviews)item.Based on the above,this study is intended to facilitate the evidence transformation of music therapy in Alzheimer's Disease.Method:Cochrane Library,Web of Science,Embase and PubMed were searched from 2017-2021,to obtain the systematic reviews of music therapy among Alzheimer’s Disease.We used the AMSTAR,to evaluate their methodological quality.Additionally,their compliance with 16 AMSTAR items was investigated.Results:12 systematic reviews were included in this study.The methodological quality of 10 articles was“very low”,1 article was“low”,and 1 article was“high”.The 12 systematic reviews had 25%to 100%compliance with 16 AMSTAR items.Conclusion:The methodological quality of systematic reviews of music therapy among Alzheimer’s Disease in the recent five years is not high,and needs to be further improved.Future research should continue to explore the factors that affect their methodological quality,to promote the transformation of evidence-based evidence.

Methodological Approach to Regulating CO_(2eq)Emissions from Major Energy Transition Projects in Sub-Saharan Africa:The Case of Hydroelectricity

The energy transition,validated by 194 countries at the end of CoP21 in Paris,requires new development design methods.This requirement,for the sub-Saharan African countries(SAC),could be an opportunity to finance their development.Following the mixed results of the Clean Development Mechanism(CDM),partly due to its rather restrictive selection criterion,the desire to implement carbon asset transfer mechanisms is proposed by many countries including Cameroon.However,the success of such a mechanism would be guaranteed by encouraging policies to regulate emissions.It is in this perspective that our work falls.It aims at proposing a regulation approach for major projects.We have dwelt on hydroelectric projects.To do this,we ordered considering their quantitative feature,113 projects or visions proposed by 37 countries.Subsequently,a classification of projects according to compartments and trends was made.We finally pointed out 6 visions,including the mitigation in production,mitigation in distribution or service,adaptation in production,mitigation in transport,adaptation in distribution or service,and the adaptation in transport.The regulation methodology proposed for mitigation projects in the hydroelectric sector on a variable threshold hypothesis has led us to three trends in regulation.

Methodological Research in the Field of Civil Aviation Safety

In order to promote the application and development of civil aviation safety(CAS)in the field of safety and enrich the theoretical system of CAS research,the methodology of CAS was studied.The definition of CAS was reconstructed,its connotation was explained from four aspects,and its research object was clarified.This paper discussed the mechanism of CAS,that is,to maintain system security through the establishment of safety prevention and control system(SPCS),and explained the research content of CAS from theory and technology application.Five principles and applicable methods for CAS research were summarized.In addition,it put forward the general procedure of CAS research,explained the specific content and implementation method or basis of each step.The research results show that the methodology of CAS is a systematic theoretical system with certain guiding significance,combined with the mechanism,research content,research principles and methods,and research procedures of CAS.

Unsatisfied methodological qualities assessment of systematic reviews/Meta-analyses on Chinese medicine for stroke and their risk factors

Background:Stroke is not only high in morbidity and mortality but also poses a great burden of disease and it is also the most reported disease in Chinese medicine systematic reviews.Therefore,the quality of such evidence couldn’t be ignored.This study aims to use a measurement tool to assess systematic reviews(AMSTAR)to assess the methodological qualities of SR/Meta-analyses of Chinese medicine on stroke.Methods:Systematic searching of seven electronic databases and PROSPERO registration platform was carried out.Two researchers separately selected studies,extracted bibliographical characteristics and scored every included study independently after training.Total score and the proportion of each item completion were explored in different subgroup comparisons.Spearman rank correlation and multivariable logistic regression were used to measure the association between bibliographical characteristics and total score or each item.Results:Total average score of AMSTAR 1.0 checklists of 234 systematic reviews/Meta-analyses was 4.47(95%CI 4.27–4.68)and the qualities were unsatisfied especially in terms of priori setting(2.14%),grey literature inclusion(5.13%),providing a list of excluded studies(2.14%)and conflict of interest(0.00%).No improvement was found in 3 years even after the publication of AMSTAR.Chinese or nonregistered systematic reviews/Meta-analyses showed even worse methodological qualities(P<0.01).Positive correlation was found between individual items and number of pages,number of authors,research questions,languages or Meta-analyse separately(P<0.05).Conclusion:The methodological qualities of systematic reviews/Meta-analyses of Chinese medicine on stroke are poor especially Chinese studies,non-registered studies,brief studies and studies without Meta-analyse or cooperation.There is no obvious improvement over these years even after the publication of AMSTAR tool,so it is urgent to promote the use of AMSTAR or develop other efficient methods to control the quantity and monitor the quality in future.

Sociolinguistic Research in Single Parent Families in China: a Methodological Perspective

It is extremely difficult to collect naturally occurring interactions in private settings.In this article,I discuss the back⁃ground of the research,and show the evidence that where the research can fit into the literature,and discuss the possible strategies that we can use to collect naturally occurring interactions in informal settings.

Researching Forms of Shadow Education:Methodological Challenges and Complexities of Private Supplementary Tutoring in Myanmar

Purpose:The growing literature on private supplementary tutoring,widely known as shadow education,addresses multiple dimensions and roles.However,many studies inadequately capture the diversity and implications of different forms of tutoring.This paper examines these matters in Myanmar,highlighting complexities and ambiguities in descriptors and in the nature of provision.Design/Approach/Methods:Using a mixed-methods design,this study was conducted in Mandalay Region and Chin State.The data were obtained from interviews with I10 Grade II students,34 high school teachers,30 parents,29 private tutoring providers,and two private school owners.Findings:The article categorizes tutoring forms based on their styles and orientations,particularly lecture-type teaching and homework supervision by guides,class sizes,durations of fee-charging(e.g,annually),the number of subjects taught per tutor,and tutoring locations.The study brings the topic out of the shadows for clearer analysis of the phenomenon and thus for assessment of its implications.OriginalityNalue:The study makes a methodological contribution to the wider picture by demonstrating the need for greater clarity and precision in the national and international comparative literatures.It also underscores shortcomings of predetermined categories in questionnaires and the value of qualitative interviews.

Metadata as a Methodological Commons:From Aboutness Description to Cognitive Modeling

Metadata is data about data,which is generated mainly for resources organization and description,facilitating finding,identifying,selecting and obtaining information.With the advancement of technologies,the acquisition of metadata has gradually become a critical step in data modeling and function operation,which leads to the formation of its methodological commons.A series of general operations has been developed to achieve structured description,semantic encoding and machine-understandable information,including entity definition,relation description,object analysis,attribute extraction,ontology modeling,data cleaning,disambiguation,alignment,mapping,relating,enriching,importing,exporting,service implementation,registry and discovery,monitoring etc.Those operations are not only necessary elements in semantic technologies(including linked data)and knowledge graph technology,but has also developed into the common operation and primary strategy in building independent and knowledge-based information systems.In this paper,a series of metadata-related methods are collectively referred to as'metadata methodological commons',which has a lot of best practices reflected in the various standard specifications of the Semantic Web.In the future construction of a multi-modal metaverse based on Web 3.0,it shall play an important role,for example,in building digital twins through adopting knowledge models,or supporting the modeling of the entire virtual world,etc.Manual-based description and coding obviously cannot adapted to the UGC(User Generated Contents)and AIGC(AI Generated Contents)-based content production in the metaverse era.The automatic processing of semantic formalization must be considered as a sure way to adapt metadata methodological commons to meet the future needs of Al era.

Methodological Issues and Values Arising from the Construction of a Heritage Corridor Along Chinese Eastern Railway

The Chinese Eastern Railway(CER),which was designed by Russia in 1898 and constructed later by China,is a typical industrial cultural landscape of the 20 th century that enjoys a high uniqueness and representativeness due to its integrality and systematicness.It sits on a historic site with various kinds of resources,including architecture,railways,and other facilities.As there has been few changes with CER's route,its resources are,in fact,still serviceable to the current railway system and people living along the route.However,considering the problems,such as lack of maintenance,ignorance of the society,inappropriate renovations,etc.,attention should be paid to CER's value assessment before any reconstruction decisions are made.Although value assessment plays a very important role in the decision-making and investment-planning process,there is almost no related research on the construction of a heritage corridor along CER.Seeing that value assessment is part of the CER Heritage Corridor construction project and the values act as a reference in understanding CER as a heritage site,this paper aims to put forward a methodological guidance to identify CER's values,so that its resources will be assessed by using what we call "value typology." In addition,it also tries to promote the tools that can help to evaluate CER's values.On the basis of a methodological analysis,it finally puts forward some advices to integrating the value assessment into the decision-making process.

Emerging perovskite materials for supercapacitors:Structure,synthesis,modification,advanced characterization,theoretical calculation and electrochemical performance

As a new generation electrode materials for energy storage,perovskites have attracted wide attention because of their unique crystal structure,reversible active sites,rich oxygen vacancies,and good stability.In this review,the design and engineering progress of perovskite materials for supercapacitors(SCs)in recent years is summarized.Specifically,the review will focus on four types of perovskites,perovskite oxides,halide perovskites,fluoride perovskites,and multi-perovskites,within the context of their intrinsic structure and corresponding electrochemical performance.A series of experimental variables,such as synthesis,crystal structure,and electrochemical reaction mechanism,will be carefully analyzed by combining various advanced characterization techniques and theoretical calculations.The applications of these materials as electrodes are then featured for various SCs.Finally,we look forward to the prospects and challenges of perovskite-type SCs electrodes,as well as the future research direction.

A systematic scoping review of study methodology for randomized controlled trials investigating probiotics in athletic and physically active populations

Background:The purported ergogenic and health effects of probiotics have been a topic of great intrigue among researchers,practitioners,and the lay public alike.There has also been an increased research focus within the realm of sports science and exercise medicine on the athletic gut microbiota.However,compared to other ergogenic aids and dietary supplements,probiotics present unique study challenges.The objectives of this systematic scoping review were to identify and characterize study methodologies of randomized controlled trials investigating supplementation with probiotics in athletes and physically active individuals.Methods:Four databases(MEDLINE,CINAHL,Cochrane CENTRAL,and Cochrane Database of Systematic Reviews)were searched for randomized controlled studies involving healthy athletes or physically active individuals.An intervention with probiotics and inclusion of a control and/or placebo group were essential.Only peer-reviewed articles in English were considered,and there were no date restrictions.Results were extracted and presented in tabular form to detail study protocols,characteristics,and outcomes.Bias in randomized controlled trials was determined with the RoB 2.0 tool.Results:A total of 45 studies were included in the review,with 35 using a parallel group design and 10 using a cross-over design.Approximately half the studies used a single probiotic and the other half a multi-strain preparation.The probiotic dose ranged from 2×10^(8)to 1×10^(11)colony forming units daily,and the length of intervention was between 7 and 150 days.Fewer than half the studies directly assessed gastrointestinal symptoms,gut permeability,or the gut microbiota.The sex ratio of participants was heavily weighted toward males,and only 3 studies exclusively investigated females.Low-level adverse events were reported in only 2 studies,although the methodology of reporting varied widely.The risk of bias was generally low,although details on randomization were lacking in some studies.Conclusion:There is a substantial body of research on the effects of prob iotic supplementation in healthy athletes and physically active individuals.Considerable heterogeneity in probiotic selection and dosage as well as outcome measures has made clinical and mechanistic interpretation challenging for both health care practitioners and researchers.Attention to issues of randomization of participants,treatments and interventions,selection of outcomes,demographics,and reporting of adverse events will facilitate more trustworthy interpretation of probiotic study results and inform evidence-based guidelines.

Enhancing wood efficiency through comprehensive wood flow analysis:Methodology and strategic insights

Wood,an essential natural resource in human civilization,remains widely used despite advances in technology and material substitution.The surge in greenhouse gas emissions and environmental concerns accentuates the need for optimizing wood utilization.Material flow analysis is a powerful tool for tracking material flows and stocks,aiding resource management and environmental decision-making.However,the full extent of its methodological dimensions,particularly within the context of the wood supply chain,remains relatively unexplored.In this study,we delve into the existing literature on wood flow analysis,discussing its primary objectives,materials involved,temporal and spatial scales,data sources,units,and conversion factors.Additionally,data uncertainty,data reconciliation and crucial assumptions in material flow analysis are highlighted in this paper.Key findings reveal the significance of wood cascading and substitution effects by replacing non-wood materials,where they can reduce greenhouse gas emissions more than the natural carbon sink of forests and wood products.The immediate impact of short-term wood cascading might not be as robust as the substitution effect,with energy substitution showcasing better results than material substitution.However,it's crucial to note that these conclusions could experience significant reversal from a long-term and global perspective.Strategies for improving wood efficiency involve maximizing material use,advancing construction technologies,extending product lifespans,promoting cascade use,and optimizing energy recovery processes.The study underscores the need for standardized approaches in wood flow analysis and emphasizes the potential of wood efficiency strategies in addressing environmental challenges.

Recovery of Li, Ni, Co and Mn from spent lithium-ion batteries assisted by organic acids: Process optimization and leaching mechanism

The proper recycling of spent lithium-ion batteries(LIBs)can promote the recovery and utilization of valuable resources,while also negative environmental effects resulting from the presence of toxic and hazardous substances.In this study,a new environmentally friendly hydro-metallurgical process was proposed for leaching lithium(Li),nickel(Ni),cobalt(Co),and manganese(Mn)from spent LIBs using sulfuric acid with citric acid as a reductant.The effects of the concentration of sulfuric acid,the leaching temperature,the leaching time,the solid-liquid ratio,and the reducing agent dosage on the leaching behavior of the above elements were investigated.Key parameters were optimized using response surface methodology(RSM)to maximize the recovery of metals from spent LIBs.The maxim-um recovery efficiencies of Li,Ni,Co,and Mn can reach 99.08%,98.76%,98.33%,and 97.63%.under the optimized conditions(the sulfuric acid concentration was 1.16 mol/L,the citric acid dosage was 15wt%,the solid-liquid ratio was 40 g/L,and the temperature was 83℃ for 120 min),respectively.It was found that in the collaborative leaching process of sulfuric acid and citric acid,the citric acid initially provided strong reducing CO_(2)^(-),and the transition metal ions in the high state underwent a reduction reaction to produce transition metal ions in the low state.Additionally,citric acid can also act as a proton donor and chelate with lower-priced transition metal ions,thus speeding up the dissolution process.

3D genome organization and its study in livestock breeding

Eukaryotic genomes are hierarchically packaged into cell nucleus,affecting gene regulation.The genome is organized into multiscale structural units,including chromosome territories,compartments,topologically associating domains(TADs),and DNA loops.The identification of these hierarchical structures has benefited from the development of experimental approaches,such as 3C-based methods(Hi-C,ChIA-PET,etc.),imaging tools(2D-FISH,3D-FISH,Cryo-FISH,etc.)and ligation-free methods(GAM,SPRITE,etc.).In recent two decades,numerous studies have shown that the 3D organization of genome plays essential roles in multiple cellular processes via various mechanisms,such as regulating enhancer activity and promoter-enhancer interactions.However,there are relatively few studies about the 3D genome in livestock species.Therefore,studies for exploring the function of 3D genomes in livestock are urgently needed to provide a more comprehensive understanding of potential relationships between the genome and production traits.In this review,we summarize the recent advances of 3D genomics and its biological functions in human and mouse studies,drawing inspiration to explore the 3D genomics of livestock species.We then mainly focus on the biological functions of 3D genome organization in muscle development and its implications in animal breeding.