The microcontact printing(μCP) technology available for patterning protein, DNA hybridization, immunoassay and cellular cocultures onto solid surface are reviewed. This review describes some of the techniques current...The microcontact printing(μCP) technology available for patterning protein, DNA hybridization, immunoassay and cellular cocultures onto solid surface are reviewed. This review describes some of the techniques currently employed for creating two-dimensional biomolecular microarray, and the research results regarding their effectiveness. In addition, the applications of the impact of μCP technology in the field of biosciences are also presented.展开更多
The adhesion of single asperity contacting with a rigid flat is investigated. The microcontact model of the deformable asperity is established utilizing fractal geometry, which makes the resuRed adhesion model to rela...The adhesion of single asperity contacting with a rigid flat is investigated. The microcontact model of the deformable asperity is established utilizing fractal geometry, which makes the resuRed adhesion model to relate with the surface characteristics that the asperity belongs to. The Dugdale approximation is utilized to consider the adhesive interaction within and outside the contact area. Then the model for solving the elastic-plastic adhesion of single asperity is presented by combing the Maugis-Dugdale（MD） model. To illustrate the necessity of considering the plastic deformation in microcontact, simulations of the relationship between the adhesive contact load and the interference of the asperity are performed. The result shows that the presented model is more suitable for the solution of the elastic-plastic microcontact of spherical asperity due to intermolecular adhesive interactions.展开更多
An elastic stamp was produced by molding poly(dimethylsiloxane)(PDMS) against a master with micro\|patterns on the surface. Then a procedure named microcontact printing was carried out on the glass substrate with the ...An elastic stamp was produced by molding poly(dimethylsiloxane)(PDMS) against a master with micro\|patterns on the surface. Then a procedure named microcontact printing was carried out on the glass substrate with the ink of an octadecylsiloxane(OTS) solution. The OTS reacted with the glass and formed a self\|assembly monolayer, and the process produced hydrophobic micro\|patterns on hydrophilic substrate. Owing to a simple hydrophobic interaction between the CuSO\-4 solution and the monolayer, a regular CuSO\-4 micro\|crystal lattice could be produced.展开更多
A novel method using a combination of microcontact printing(μCP) technique, surface-directed condensation and surface- directed dewetting has been developed to fabricate patterned polymer films on gold substrates. Th...A novel method using a combination of microcontact printing(μCP) technique, surface-directed condensation and surface- directed dewetting has been developed to fabricate patterned polymer films on gold substrates. These patterned polymer films can serve as resists in the argon ion etching effectively to transfer patterns into the underlying gold substrates. This method is flexible in controlling the shape and feature size of the patterns in the polymer resists by simply adjusting the concentration of polymer solution, and especially it also provides a route to sub-micrometer sized features by using an original template with micrometer sized features.展开更多
基金Nankai U niversity Science and Technology Fundation(No.A0 15 4 4 ) and Tianjin Science and TechnologyDevelop Program(2 0 0 4 )
文摘The microcontact printing(μCP) technology available for patterning protein, DNA hybridization, immunoassay and cellular cocultures onto solid surface are reviewed. This review describes some of the techniques currently employed for creating two-dimensional biomolecular microarray, and the research results regarding their effectiveness. In addition, the applications of the impact of μCP technology in the field of biosciences are also presented.
基金China Post Doctor Science Foundation(No. 20070420748)Fujian Provincial Natural Science Foundation of China(E0610032).
文摘The adhesion of single asperity contacting with a rigid flat is investigated. The microcontact model of the deformable asperity is established utilizing fractal geometry, which makes the resuRed adhesion model to relate with the surface characteristics that the asperity belongs to. The Dugdale approximation is utilized to consider the adhesive interaction within and outside the contact area. Then the model for solving the elastic-plastic adhesion of single asperity is presented by combing the Maugis-Dugdale（MD） model. To illustrate the necessity of considering the plastic deformation in microcontact, simulations of the relationship between the adhesive contact load and the interference of the asperity are performed. The result shows that the presented model is more suitable for the solution of the elastic-plastic microcontact of spherical asperity due to intermolecular adhesive interactions.
基金SupportedbytheChineseNationalFoundationofEminentYoungScholars(B) (No .5 992 82 0 2 ) .
文摘An elastic stamp was produced by molding poly(dimethylsiloxane)(PDMS) against a master with micro\|patterns on the surface. Then a procedure named microcontact printing was carried out on the glass substrate with the ink of an octadecylsiloxane(OTS) solution. The OTS reacted with the glass and formed a self\|assembly monolayer, and the process produced hydrophobic micro\|patterns on hydrophilic substrate. Owing to a simple hydrophobic interaction between the CuSO\-4 solution and the monolayer, a regular CuSO\-4 micro\|crystal lattice could be produced.
文摘A novel method using a combination of microcontact printing(μCP) technique, surface-directed condensation and surface- directed dewetting has been developed to fabricate patterned polymer films on gold substrates. These patterned polymer films can serve as resists in the argon ion etching effectively to transfer patterns into the underlying gold substrates. This method is flexible in controlling the shape and feature size of the patterns in the polymer resists by simply adjusting the concentration of polymer solution, and especially it also provides a route to sub-micrometer sized features by using an original template with micrometer sized features.
