BACKGROUND Marginal zone lymphoma(MZL)is an indolent non-Hodgkin B cell lymphoma with various architectural pattern including perifollicular,follicular colonization,nodular,micronodular,and diffuse patterns.A scleroti...BACKGROUND Marginal zone lymphoma(MZL)is an indolent non-Hodgkin B cell lymphoma with various architectural pattern including perifollicular,follicular colonization,nodular,micronodular,and diffuse patterns.A sclerotic variant has not been previously reported and represents a diagnostic pitfall.CASE SUMMARY A 66-year-old male developed left upper extremity swelling.Chest computed tomography(CT)in September 2020 showed 14 cm mass in left axilla.Needle core biopsy of axillary lymph node showed sclerotic tissue with atypical B lymphoid infiltrate but was non-diagnostic.Excisional biopsy was performed for diagnosis and showed extensive fibrosis and minor component of infiltrating B cells.Flow cytometry showed a small population of CD5-,CD10-,kappa restricted B cells.Monoclonal immunoglobulin heavy chain and light chain gene rearrangement were identified.Upon being diagnosed with MZL,patient was treated with rituximab,cyclophosphamide,doxorubicin,vincristine,and prednisone and achieved complete remission by positron emission tomography/CT.CONCLUSION This is an important case report because by morphology this case could have easily been overlooked as non-specific fibrosis with chronic inflammation representing a significant diagnostic pitfall.Moreover,this constitutes a new architectural pattern.While sclerotic lymphomas have rarely been described(often misdiagnosed as retroperitoneal fibrosis),we do not know of any cases describing this architectural presentation of MZL.展开更多
This paper presents the idea of software reuse and object-oriented analysis technology and disscusses the development step of object-oriented analysis ,as well as the implementation model of enterprise's MIS which...This paper presents the idea of software reuse and object-oriented analysis technology and disscusses the development step of object-oriented analysis ,as well as the implementation model of enterprise's MIS which included four parts:objects model,control model ,interface model and implement explains.展开更多
计算机技术的快速发展推动着水泥厂自动化水平的提高,世界各大水泥厂正在越来越迫切地追求完备的信息管理系统。针对这一需求,这里介绍了MIS系统服务器的软硬件平台、MIS系统与外界的通讯与网络连接,应用西门子SIMATIC IT Historian以及...计算机技术的快速发展推动着水泥厂自动化水平的提高,世界各大水泥厂正在越来越迫切地追求完备的信息管理系统。针对这一需求,这里介绍了MIS系统服务器的软硬件平台、MIS系统与外界的通讯与网络连接,应用西门子SIMATIC IT Historian以及Reporting Framework软件实现对水泥厂自动化系统的信息管理。展开更多
文摘BACKGROUND Marginal zone lymphoma(MZL)is an indolent non-Hodgkin B cell lymphoma with various architectural pattern including perifollicular,follicular colonization,nodular,micronodular,and diffuse patterns.A sclerotic variant has not been previously reported and represents a diagnostic pitfall.CASE SUMMARY A 66-year-old male developed left upper extremity swelling.Chest computed tomography(CT)in September 2020 showed 14 cm mass in left axilla.Needle core biopsy of axillary lymph node showed sclerotic tissue with atypical B lymphoid infiltrate but was non-diagnostic.Excisional biopsy was performed for diagnosis and showed extensive fibrosis and minor component of infiltrating B cells.Flow cytometry showed a small population of CD5-,CD10-,kappa restricted B cells.Monoclonal immunoglobulin heavy chain and light chain gene rearrangement were identified.Upon being diagnosed with MZL,patient was treated with rituximab,cyclophosphamide,doxorubicin,vincristine,and prednisone and achieved complete remission by positron emission tomography/CT.CONCLUSION This is an important case report because by morphology this case could have easily been overlooked as non-specific fibrosis with chronic inflammation representing a significant diagnostic pitfall.Moreover,this constitutes a new architectural pattern.While sclerotic lymphomas have rarely been described(often misdiagnosed as retroperitoneal fibrosis),we do not know of any cases describing this architectural presentation of MZL.
文摘This paper presents the idea of software reuse and object-oriented analysis technology and disscusses the development step of object-oriented analysis ,as well as the implementation model of enterprise's MIS which included four parts:objects model,control model ,interface model and implement explains.
文摘计算机技术的快速发展推动着水泥厂自动化水平的提高,世界各大水泥厂正在越来越迫切地追求完备的信息管理系统。针对这一需求,这里介绍了MIS系统服务器的软硬件平台、MIS系统与外界的通讯与网络连接,应用西门子SIMATIC IT Historian以及Reporting Framework软件实现对水泥厂自动化系统的信息管理。
