Glycosmis longipetala F. J. Mou ＆ D. X. Zhang is described from Guangxi and Yunnan provinces in southwestern China. The new species is similar to G. cochinchinensis （Lour.） Pierre ex Engl. by its simple leaves, but...Glycosmis longipetala F. J. Mou ＆ D. X. Zhang is described from Guangxi and Yunnan provinces in southwestern China. The new species is similar to G. cochinchinensis （Lour.） Pierre ex Engl. by its simple leaves, but distinguishable in having long-elliptic or oblanceolate （vs. ovate） leaves, long-ovoid to ellipsoid （vs. ovoid） floral buds, ovaries with many tubercles （vs. smooth） and glabrous （vs. pubescent） stamens. The pollen grains of the new species are 23.9±3.09 （20.8-27.0）×22.0±1.80 （20.4-24.4）μm in size with reticulate exine ornamentation in equatorial area and foveolate in polar area. The chromosome number of the new species is 2n=72.展开更多
Primary squamous cell carcinoma(SCC) of the liver is rare and reported sporadically.Up to date,only 24 such cases have been reported in the literature.It is associated with hepatic teratoma,congenital cysts,solitary b...Primary squamous cell carcinoma(SCC) of the liver is rare and reported sporadically.Up to date,only 24 such cases have been reported in the literature.It is associated with hepatic teratoma,congenital cysts,solitary benign non-parasitic hepatic cysts,hepatolithiasis/Caroli's disease or cirrhosis.We reported a case of primary SCC of the liver associated with multiple intrahepatic cholesterol gallstones.The patient underwent hepatectomy followed by radiotherapy,and has survived for over 19 mo without recurrence.展开更多
Mesozoic volcanic rocks in the eastern part of the North Dabi e Mountains are rich in Na (Na\-2O=\{4.03%\}, Na\-2O/K\-2O=\{1.31\}), Sr and Ba , and high in Sr/Y ratio but low in Nb, Y and H REE. They have experienced ...Mesozoic volcanic rocks in the eastern part of the North Dabi e Mountains are rich in Na (Na\-2O=\{4.03%\}, Na\-2O/K\-2O=\{1.31\}), Sr and Ba , and high in Sr/Y ratio but low in Nb, Y and H REE. They have experienced strong fractionation of REE \, and are similar to adakite in geochemical characteristics. The U-Pb dating of zircon from the volcanic rocks is Ma, belonging to Early Cretaceous. These rocks are similar to the volcanic rocks of North Huaiyang not only in age and rare-earth element and trace element geochemistry, but also in the formati on temperature and pressure of the minerals. The results indicated that the dela mination of mountain root and underplating of mafic-ultramafic magma had happen ed in the Dabie orogen before Early Cretaceous. Mesozoic magmatism was intense i n the North Dabie Mountains, including the intrusion of mafic-ultramafic magma, uplifting of gneiss dome, explosion of volcanic rocks and intrusion of granitic magma. The Mesozoic volcanic rocks in the eastern part of the North Dabie Mount ains may be one part of the Mesozoic volcano-intrusive complex belt of North Hu aiyang. The existence of Mesozoic volcanic remnant cap means the denudation of t he Dabie orogenic belt was not very strong since Early Cretaceous.展开更多
AIM:To assess the prevalence of human papilloma virus(HPV) in esophageal squamous cell carcinoma(ESCC) in the south-eastern region of Poland.METHODS:The study population consisted of 56 ESCC patients and 35 controls.T...AIM:To assess the prevalence of human papilloma virus(HPV) in esophageal squamous cell carcinoma(ESCC) in the south-eastern region of Poland.METHODS:The study population consisted of 56 ESCC patients and 35 controls.The controls were patients referred to our department due to other nonesophageal and non-oncological disorders with no gross or microscopic esophageal pathology as confirmed by endoscopy and histopathology.In the ESCC patients,samples were taken from normal mucosa(56 mucosa samples) and from the tumor(56 tumor samples).Tissue samples from the controls were taken from normal mucosa of the middle esophagus(35 control samples).Quantitative determination of DNA was carried out using a spectrophotometric method.Genomic DNA was isolated using the QIAamp DNA Midi Kit.HPV infection was identified following PCR amplification of the HPV gene sequence,using primers MY09 and MY11 complementary to the genome sequence of at least 33 types of HPV.The sequencing results were computationally analyzed using the basic local alignment search tool database.RESULTS:In tumor samples,HPV DNA was identified in 28 of 56 patients(50%).High risk HPV phenotypes(16 or/and 18) were found in 5 of 56 patients(8.9%),low risk in 19 of 56 patients(33.9%) and other types of HPV(37,81,97,CP6108) in 4 of 56 patients(7.1%).In mucosa samples,HPV DNA was isolated in 21 of 56 patients(37.5%).High risk HPV DNA was confirmed in 3 of 56 patients(5.3%),low risk HPV DNA in 12 of 56 patients(21.4%),and other types of HPV in 6 of 56 patients(10.7%).In control samples,HPV DNA was identified in 4 of 35 patients(11.4%) with no high risk HPV.The occurrence of HPV in ESCC patients was significantly higher than in the controls [28 of 56(50%) vs 4 of 35(11.4%),P < 0.001].In esophageal cancer patients,both in tumor and mucosa samples,the predominant HPV phenotypes were low risk HPV,isolated 4 times more frequently than high risk phenotypes [19 of 56(33.9%) vs 5 of 56(8.9%),P < 0.001].A higher prevalence of HPV was identified in female patients(71.4% vs 46.9%).Accordingly,the high risk phenotypes were isolated more frequently in female patients and this difference reached statistical significance [3 of 7(42.9%) vs 2 of 49(4.1%),P < 0.05].Of the pathological characteristics,only an infiltrative pattern of macroscopic tumor type significantly correlated with the presence of HPV DNA in ESCC samples [20 of 27(74.1%) vs 8 of 29(27.6%) for ulcerative or protruding macroscopic type,P < 0.05].The occurrence of total HPV DNA and both HPV high or low risk phenotypes did not significantly differ with regard to particular grades of cellular differentiation,phases in depth of tumor infiltration,grades of nodal involvement and stages of tumor progression.CONCLUSION:Low risk HPV phenotypes could be one of the co-activators or/and co-carcinogens in complex,progressive,multifactorial and multistep esophageal carcinogenesis.展开更多
Cell proliferation is accompanied with changing levels of intracellular calmodulin (CaM) and its activation.Prior data from synchronized cell population could not actually stand for various CaM levels in different pha...Cell proliferation is accompanied with changing levels of intracellular calmodulin (CaM) and its activation.Prior data from synchronized cell population could not actually stand for various CaM levels in different phases of cell cycle.Here,based upon quantitative measurement of fluorescence in individual cells,a method was developed to investigate intracellular total CaM and Ca^2+-activated CaM contents. Intensity of CaM immunoflurescence gave total CaM level,and Ca^2+-activated CaM was measured by fluorescence intensity of CaM antagonist trifluoperazine (TFP).In mouse erythroleukemia (MEL) cells,total CaM level increased from G1 through S to G2M,reaching a maximum of 2-fold increase,then reduced to half amount after cell division.Meanwhile,Ca^2+-activated CaM also in creased through the cell cycle(G1,S,G2M).Increasing observed in G1 meant that the entry of cells from G1 into S phase may require CaM accumulation,and,equally or even more important,Ca^2+-dependent activation of CaM.Ca^2+-activated CaM decreased after cell division.The results suggested that CaM gene expression and C^2+-modulated CaM activation act synergistically to accomplish the cell cycle progression.展开更多
SAC Administrator Tian Shihong received the visiting delegation of GCC Standardization Organization(GSO)led by its Secretary-General Nabil A.Molla with a MOU signed between the two sides for further standardization co...SAC Administrator Tian Shihong received the visiting delegation of GCC Standardization Organization(GSO)led by its Secretary-General Nabil A.Molla with a MOU signed between the two sides for further standardization cooperation on August 10,2017.The two sides held in-depth communications on various展开更多
On November 27,2017,under the government cooperation framework of China and Thailand,Beijing Tengyuxinwei Technology Co.,Ltd.(BTTCL),affiliated to the China Great Wall Industry Corporation(CGWIC),signed a MOU of‘Join...On November 27,2017,under the government cooperation framework of China and Thailand,Beijing Tengyuxinwei Technology Co.,Ltd.(BTTCL),affiliated to the China Great Wall Industry Corporation(CGWIC),signed a MOU of‘Joint Construction of HONGYAN-SAT Constellation’with Thailand Kasetsart University(KU).Under this MOU,BTTCL and KU will cooperate in the areas of HONGYAN-展开更多
基金supported by National Natural Science Foundation of China (30370107).
文摘Glycosmis longipetala F. J. Mou ＆ D. X. Zhang is described from Guangxi and Yunnan provinces in southwestern China. The new species is similar to G. cochinchinensis （Lour.） Pierre ex Engl. by its simple leaves, but distinguishable in having long-elliptic or oblanceolate （vs. ovate） leaves, long-ovoid to ellipsoid （vs. ovoid） floral buds, ovaries with many tubercles （vs. smooth） and glabrous （vs. pubescent） stamens. The pollen grains of the new species are 23.9±3.09 （20.8-27.0）×22.0±1.80 （20.4-24.4）μm in size with reticulate exine ornamentation in equatorial area and foveolate in polar area. The chromosome number of the new species is 2n=72.
文摘Primary squamous cell carcinoma(SCC) of the liver is rare and reported sporadically.Up to date,only 24 such cases have been reported in the literature.It is associated with hepatic teratoma,congenital cysts,solitary benign non-parasitic hepatic cysts,hepatolithiasis/Caroli's disease or cirrhosis.We reported a case of primary SCC of the liver associated with multiple intrahepatic cholesterol gallstones.The patient underwent hepatectomy followed by radiotherapy,and has survived for over 19 mo without recurrence.
基金theChineseAcademyofGeologicalSciences (No .I50C0 0 2 0 04)ChineseContinentalSienceDrill (No .2 0 0 0 4 0 90 )
文摘Mesozoic volcanic rocks in the eastern part of the North Dabi e Mountains are rich in Na (Na\-2O=\{4.03%\}, Na\-2O/K\-2O=\{1.31\}), Sr and Ba , and high in Sr/Y ratio but low in Nb, Y and H REE. They have experienced strong fractionation of REE \, and are similar to adakite in geochemical characteristics. The U-Pb dating of zircon from the volcanic rocks is Ma, belonging to Early Cretaceous. These rocks are similar to the volcanic rocks of North Huaiyang not only in age and rare-earth element and trace element geochemistry, but also in the formati on temperature and pressure of the minerals. The results indicated that the dela mination of mountain root and underplating of mafic-ultramafic magma had happen ed in the Dabie orogen before Early Cretaceous. Mesozoic magmatism was intense i n the North Dabie Mountains, including the intrusion of mafic-ultramafic magma, uplifting of gneiss dome, explosion of volcanic rocks and intrusion of granitic magma. The Mesozoic volcanic rocks in the eastern part of the North Dabie Mount ains may be one part of the Mesozoic volcano-intrusive complex belt of North Hu aiyang. The existence of Mesozoic volcanic remnant cap means the denudation of t he Dabie orogenic belt was not very strong since Early Cretaceous.
基金Supported by Medical University of Lublin,Scientific Research Grant
文摘AIM:To assess the prevalence of human papilloma virus(HPV) in esophageal squamous cell carcinoma(ESCC) in the south-eastern region of Poland.METHODS:The study population consisted of 56 ESCC patients and 35 controls.The controls were patients referred to our department due to other nonesophageal and non-oncological disorders with no gross or microscopic esophageal pathology as confirmed by endoscopy and histopathology.In the ESCC patients,samples were taken from normal mucosa(56 mucosa samples) and from the tumor(56 tumor samples).Tissue samples from the controls were taken from normal mucosa of the middle esophagus(35 control samples).Quantitative determination of DNA was carried out using a spectrophotometric method.Genomic DNA was isolated using the QIAamp DNA Midi Kit.HPV infection was identified following PCR amplification of the HPV gene sequence,using primers MY09 and MY11 complementary to the genome sequence of at least 33 types of HPV.The sequencing results were computationally analyzed using the basic local alignment search tool database.RESULTS:In tumor samples,HPV DNA was identified in 28 of 56 patients(50%).High risk HPV phenotypes(16 or/and 18) were found in 5 of 56 patients(8.9%),low risk in 19 of 56 patients(33.9%) and other types of HPV(37,81,97,CP6108) in 4 of 56 patients(7.1%).In mucosa samples,HPV DNA was isolated in 21 of 56 patients(37.5%).High risk HPV DNA was confirmed in 3 of 56 patients(5.3%),low risk HPV DNA in 12 of 56 patients(21.4%),and other types of HPV in 6 of 56 patients(10.7%).In control samples,HPV DNA was identified in 4 of 35 patients(11.4%) with no high risk HPV.The occurrence of HPV in ESCC patients was significantly higher than in the controls [28 of 56(50%) vs 4 of 35(11.4%),P < 0.001].In esophageal cancer patients,both in tumor and mucosa samples,the predominant HPV phenotypes were low risk HPV,isolated 4 times more frequently than high risk phenotypes [19 of 56(33.9%) vs 5 of 56(8.9%),P < 0.001].A higher prevalence of HPV was identified in female patients(71.4% vs 46.9%).Accordingly,the high risk phenotypes were isolated more frequently in female patients and this difference reached statistical significance [3 of 7(42.9%) vs 2 of 49(4.1%),P < 0.05].Of the pathological characteristics,only an infiltrative pattern of macroscopic tumor type significantly correlated with the presence of HPV DNA in ESCC samples [20 of 27(74.1%) vs 8 of 29(27.6%) for ulcerative or protruding macroscopic type,P < 0.05].The occurrence of total HPV DNA and both HPV high or low risk phenotypes did not significantly differ with regard to particular grades of cellular differentiation,phases in depth of tumor infiltration,grades of nodal involvement and stages of tumor progression.CONCLUSION:Low risk HPV phenotypes could be one of the co-activators or/and co-carcinogens in complex,progressive,multifactorial and multistep esophageal carcinogenesis.
文摘Cell proliferation is accompanied with changing levels of intracellular calmodulin (CaM) and its activation.Prior data from synchronized cell population could not actually stand for various CaM levels in different phases of cell cycle.Here,based upon quantitative measurement of fluorescence in individual cells,a method was developed to investigate intracellular total CaM and Ca^2+-activated CaM contents. Intensity of CaM immunoflurescence gave total CaM level,and Ca^2+-activated CaM was measured by fluorescence intensity of CaM antagonist trifluoperazine (TFP).In mouse erythroleukemia (MEL) cells,total CaM level increased from G1 through S to G2M,reaching a maximum of 2-fold increase,then reduced to half amount after cell division.Meanwhile,Ca^2+-activated CaM also in creased through the cell cycle(G1,S,G2M).Increasing observed in G1 meant that the entry of cells from G1 into S phase may require CaM accumulation,and,equally or even more important,Ca^2+-dependent activation of CaM.Ca^2+-activated CaM decreased after cell division.The results suggested that CaM gene expression and C^2+-modulated CaM activation act synergistically to accomplish the cell cycle progression.
文摘SAC Administrator Tian Shihong received the visiting delegation of GCC Standardization Organization(GSO)led by its Secretary-General Nabil A.Molla with a MOU signed between the two sides for further standardization cooperation on August 10,2017.The two sides held in-depth communications on various
文摘On November 27,2017,under the government cooperation framework of China and Thailand,Beijing Tengyuxinwei Technology Co.,Ltd.(BTTCL),affiliated to the China Great Wall Industry Corporation(CGWIC),signed a MOU of‘Joint Construction of HONGYAN-SAT Constellation’with Thailand Kasetsart University(KU).Under this MOU,BTTCL and KU will cooperate in the areas of HONGYAN-
