The Landau damping behavior in a cylindrical inhomogeneous warm magnetized plasma waveguide has been studied.The radial inhomogeneity for different characteristic lengths(L0) with strong spatial dispersion has been ...The Landau damping behavior in a cylindrical inhomogeneous warm magnetized plasma waveguide has been studied.The radial inhomogeneity for different characteristic lengths(L0) with strong spatial dispersion has been taken into account.The analyses have been considered for two limits ωce 〈 ωpe and ωce 〉 ωpe. Due to the radial inhomogeneity of the plasma, all essential equations for studying the Landau damping are calculated in the Bessel–Furrier and differential Bessel–Furrier expansions. The dependence of Landau damping on the inhomogeneity, temperature and external magnetic field for electrostatic modes is scrutinized and described in detail through numerical calculations. The associated numerical results are presented and discussed.展开更多
The generalized dispersion equation for longitudinal oscillation in an unmagnetized, collisionless, isotropic and relativistic plasma is derived in the context of nonextensive q-distribution. An analytical expression ...The generalized dispersion equation for longitudinal oscillation in an unmagnetized, collisionless, isotropic and relativistic plasma is derived in the context of nonextensive q-distribution. An analytical expression for the Landau damping is obtained in an ultra-relativistic regime, which is related to q-parameter. In the limit q →1, the result based on the relativistic Maxwellian distribution is recovered. It is shown that the interactions between the wave and particles are stronger and the waves are more strongly damped for lower values of q-parameter. The results are explained by the increased number of superthermal particles or low velocity particles contained in the plasma with the nonextensive distribution.展开更多
The damping decrement of Landau damping and the effect of thermal velocity on the frequency spectrum of a propagating wave in a bounded plasma column are investigated.The magnetized plasma column partially filling a c...The damping decrement of Landau damping and the effect of thermal velocity on the frequency spectrum of a propagating wave in a bounded plasma column are investigated.The magnetized plasma column partially filling a cylindrical metallic tube is considered to be collisionless and non-degenerate.The Landau damping is due to the thermal motion of charge carriers and appears whenever the phase velocity of the plasma waves exceeds the thermal velocity of carriers.The analysis is based on a self-consistent kinetic theory and the solutions of the wave equation in a cylindrical plasma waveguide are presented using Vlasov and Maxwell equations.The hybrid mode dispersion equation for the cylindrical plasma waveguide is obtained through the application of appropriate boundary conditions to the plasma-vacuum interface.The dependence of Landau damping on plasma parameters and the effects of the metallic tube boundary on the dispersion characteristics of plasma and waveguide modes are investigated in detail through numerical calculations.展开更多
The solitary waves of a viscous plasma confined in a cuboid under the three types of boundary condition are theoretically investigated in the present paper.By introducing a threedimensional rectangular geometry and em...The solitary waves of a viscous plasma confined in a cuboid under the three types of boundary condition are theoretically investigated in the present paper.By introducing a threedimensional rectangular geometry and employing the reductive perturbation theory,a quasi-Kd V equation is derived in the viscous plasma and a damping solitary wave is obtained.It is found that the damping rate increases as the viscosity coefficient increases,or increases as the length and width of the rectangle decrease,for all kinds of boundary condition.Nevertheless,the magnitude of the damping rate is dominated by the types of boundary condition.We thus observe the existence of a damping solitary wave from the fact that its amplitude disappears rapidly for a → 0and b → 0,or ν→ +∞.展开更多
The dispersion of Langmuir wave(LW)in an unmagnetized collisionless plasma with regularized Kappa distributed electrons is investigated from the kinetic theory.The frequency and damping rate of LW are analyzed for the...The dispersion of Langmuir wave(LW)in an unmagnetized collisionless plasma with regularized Kappa distributed electrons is investigated from the kinetic theory.The frequency and damping rate of LW are analyzed for the parameters relating to the source region of a typeⅢsolar radio burst.It is found that the linear behavior of LW is greatly modified by the suprathermal indexκand the exponential cutoff parameterα.In the regionκ<1.5,the damping rate of LW will be much larger than the one with Maxwellian distributed electrons.Hence,the nonlinear process of LW in lowκregion may exhibit different properties in comparison with the one in largeκregion.展开更多
The dispersion relations of parallel propagating modes(Langmuir mode, right and left handed circular polarized waves) in the weak magnetic field limit |ω-k·v| 〉〉 ? are considered for ultra-relativistic ar...The dispersion relations of parallel propagating modes(Langmuir mode, right and left handed circular polarized waves) in the weak magnetic field limit |ω-k·v| 〉〉 ? are considered for ultra-relativistic arbitrary degenerate electron plasma. The results are presented in terms of moments of Fermi-Dirac distribution. The increase in the electron equilibrium number density from negative large(weakly degenerate) to positive large(highly degenerate) values of μ/Te is observed(where μ is the electron chemical potential and Te is the electron thermal energy). As a result, shifting of the cutoff points in all the real dispersion branches towards the higher values and increasing in the band gap between unmagnetized longitudinal and transverse modes in k-space are examined. Also, the suppression of the weak magnetic field effects in weakly magnetized right handed and left handed circular polarized waves and a decrease in the longitudinal and transverse screening effects are observed in the graphical patterns due to an increase in the equilibrium number density.展开更多
The observations of in-situ spacecraft mission in the magnetosheath and a region of thermalized subsonic plasma behind the bow shock reveal a non-linear behaviour of plasma waves. The study of waves and optics in Phys...The observations of in-situ spacecraft mission in the magnetosheath and a region of thermalized subsonic plasma behind the bow shock reveal a non-linear behaviour of plasma waves. The study of waves and optics in Physics has given the understanding of the effect of many waves coming together to form a wave field or wave packet. The common aspect of such study shows that two or more waves can superimpose constructively or destructively. The sudden high magnetic field data in the magnetosheath displays such possibility of superposition of waves. In this paper, we use the empirical mode decomposition (EMD) and Hilbert transform (HT) techniques to determine the instantaneous frequencies of low frequency plasma waves in the magnetosheath. Our analysis has shown that the turbulent behavior of magnetic field in the magnetosheath within the selected period is due to superposition of waves.展开更多
Evolution of an electrostatic plasma wave driven by a low-density ultra-relativistic electron beam in dense inhomogeneous plasma is considered. In particular, the wavelength variation as observed at fixed locations in...Evolution of an electrostatic plasma wave driven by a low-density ultra-relativistic electron beam in dense inhomogeneous plasma is considered. In particular, the wavelength variation as observed at fixed locations in the plasma is analyzed in terms of the wave characteristics. It is shown that for a negative density gradient, the observed local wavelength decreases monotonically with time, but for a positive density gradient, it first increases and then decreases with time, accompanied by reversal of the wave phase. However, in both cases the local wavelength eventually decreases with time since Landau damping becomes significant as the wavelength becomes of the order of the plasma Debye length. Results from particle-in-cell simulations agree well with theoretical analyses of the wavelength variation.展开更多
Plasma sprayed ceramic coatings are successfully used in many industrial applications,where high wear and corrosion resistance with thermal insulation are required.In this work,empirical relationships were developed t...Plasma sprayed ceramic coatings are successfully used in many industrial applications,where high wear and corrosion resistance with thermal insulation are required.In this work,empirical relationships were developed to predict the porosity and corrosion rate of alumina coatings by incorporating independently controllable atmospheric plasma spray operational parameters(input power,stand-off distance and powder feed rate)using response surface methodology(RSM).A central composite rotatable design with three factors and five levels was chosen to minimize the number of experimental conditions.Within the scope of the design space,the input power and the stand-off distance appeared to be the most significant two parameters affecting the responses among the three investigated process parameters.A linear regression relationship was also established between porosity and corrosion rate of the alumina coatings.Further,sensitivity analysis was carried out and compared with the relative impact of three process parameters on porosity level and corrosion rate to verify the measurement errors on the values of the uncertainty in estimated parameters.展开更多
Analysis of Incoherent Scatter Radar(ISR)data collected during an experiment involving alternating O/X mode pumping reveals that the high-frequency enhanced ion line(HFIL)and plasma line(HFPL)did not appear immediatel...Analysis of Incoherent Scatter Radar(ISR)data collected during an experiment involving alternating O/X mode pumping reveals that the high-frequency enhanced ion line(HFIL)and plasma line(HFPL)did not appear immediately after the onset of pumping,but were delayed by a few seconds.By examining the initial behaviors of the ion line,plasma line,and electron temperature,as well as ionosphere conditions,we find that(1)the HFIL and HFPL were delayed not only in the X mode pumping but also in the O mode pumping and(2)the HFIL was not observed prior to enhancement of the electron temperature.Our analysis suggests that(1)leakage of the X mode to the O mode pumping may not be ignored and(2)spatiotemporal uncertainties and spatiotemporal variations in the profiles of ion mass and electron density may have played important roles in the apparent failure of the Bragg condition to apply;(3)nevertheless,the absence of parametric decay instability(PDI)cannot be ruled out,due to our inability to match conditions caused by the spatiotemporal uncertainties.展开更多
Several promising plasma biomarker proteins,such as amyloid-β(Aβ),tau,neurofilament light chain,and glial fibrillary acidic protein,are widely used for the diagnosis of neurodegenerative diseases.However,little is k...Several promising plasma biomarker proteins,such as amyloid-β(Aβ),tau,neurofilament light chain,and glial fibrillary acidic protein,are widely used for the diagnosis of neurodegenerative diseases.However,little is known about the long-term stability of these biomarker proteins in plasma samples stored at-80°C.We aimed to explore how storage time would affect the diagnostic accuracy of these biomarkers using a large cohort.Plasma samples from 229 cognitively unimpaired individuals,encompassing healthy controls and those experiencing subjective cognitive decline,as well as 99 patients with cognitive impairment,comprising those with mild cognitive impairment and dementia,were acquired from the Sino Longitudinal Study on Cognitive Decline project.These samples were stored at-80°C for up to 6 years before being used in this study.Our results showed that plasma levels of Aβ42,Aβ40,neurofilament light chain,and glial fibrillary acidic protein were not significantly correlated with sample storage time.However,the level of total tau showed a negative correlation with sample storage time.Notably,in individuals without cognitive impairment,plasma levels of total protein and tau phosphorylated protein threonine 181(p-tau181)also showed a negative correlation with sample storage time.This was not observed in individuals with cognitive impairment.Consequently,we speculate that the diagnostic accuracy of plasma p-tau181 and the p-tau181 to total tau ratio may be influenced by sample storage time.Therefore,caution is advised when using these plasma biomarkers for the identification of neurodegenerative diseases,such as Alzheimer's disease.Furthermore,in cohort studies,it is important to consider the impact of storage time on the overall results.展开更多
In this research,we present the pure open multi-processing(OpenMP),pure message passing interface(MPI),and hybrid MPI/OpenMP parallel solvers within the dynamic explicit central difference algorithm for the coining pr...In this research,we present the pure open multi-processing(OpenMP),pure message passing interface(MPI),and hybrid MPI/OpenMP parallel solvers within the dynamic explicit central difference algorithm for the coining process to address the challenge of capturing fine relief features of approximately 50 microns.Achieving such precision demands the utilization of at least 7 million tetrahedron elements,surpassing the capabilities of traditional serial programs previously developed.To mitigate data races when calculating internal forces,intermediate arrays are introduced within the OpenMP directive.This helps ensure proper synchronization and avoid conflicts during parallel execution.Additionally,in the MPI implementation,the coins are partitioned into the desired number of regions.This division allows for efficient distribution of computational tasks across multiple processes.Numerical simulation examples are conducted to compare the three solvers with serial programs,evaluating correctness,acceleration ratio,and parallel efficiency.The results reveal a relative error of approximately 0.3%in forming force among the parallel and serial solvers,while the predicted insufficient material zones align with experimental observations.Additionally,speedup ratio and parallel efficiency are assessed for the coining process simulation.The pureMPI parallel solver achieves a maximum acceleration of 9.5 on a single computer(utilizing 12 cores)and the hybrid solver exhibits a speedup ratio of 136 in a cluster(using 6 compute nodes and 12 cores per compute node),showing the strong scalability of the hybrid MPI/OpenMP programming model.This approach effectively meets the simulation requirements for commemorative coins with intricate relief patterns.展开更多
The dual cylindrical inductively coupled plasma source,compared to the conventional structure of inductively coupled plasma source,can significantly improve the uniformity of plasma.It has an enhanced potential for ap...The dual cylindrical inductively coupled plasma source,compared to the conventional structure of inductively coupled plasma source,can significantly improve the uniformity of plasma.It has an enhanced potential for application in processes,such as etching and ashing.A uniform plasma can be obtained by allowing the remote plasma from the upper chamber modulate the main plasma generated in the lower chamber.In this study,a fluid model was employed to investigate a dual cylindrical inductively coupled Ar/O_(2)discharge.The effects of external parameters on electron density,electron temperature,O atomic density,and plasma uniformity in the main chamber were studied,and the reasons were analyzed.The results of this study show that remote power can control the plasma uniformity and increase the plasma density in the main chamber.As the remote power increased,plasma uniformity improved initially and then deteriorated.The main power affected the plasma density at the edge of the main chamber and can modulate the plasma density in the main chamber.The gas pressure affected both the uniformity and density of the plasma.As the gas pressure increased,the plasma uniformity deteriorated,but the free radical density improved.展开更多
In astrophysics, the boundary conditions for plasma phenomena are provided by nature and the astronomer faces the problem of understanding them from a variety of observations [Hester J J et al 1996 Astrophys. J. 456 2...In astrophysics, the boundary conditions for plasma phenomena are provided by nature and the astronomer faces the problem of understanding them from a variety of observations [Hester J J et al 1996 Astrophys. J. 456 225], on the other hand, in laboratory plasma experiments the electromagnetic boundary conditions become a major problem in the set-up of the machine that produces the plasma, an issue that has to be investigated step by step and to be modified and adapted with great patience, in particular in the case of an innovative plasma confinement experiment. The PROTO-SPHERA machine [Alladio F et al 2006 Nucl. Fusion 46 S613] is a magnetic confinement experiment, that emulates in the laboratory the jet + torus plasma configurations often observed in astrophysics: an inner magnetized jet of plasma centered on the(approximate) axis of symmetry and surrounded by a magnetized plasma torus orthogonal to this jet. The PROTO-SPHERA plasma is simply connected, i.e., no metal current conducting rod is linked to the plasma torus, while instead it is the inner magnetized plasma jet(in the following always called the plasma centerpost) that is linked to the torus. It is mandatory that no spurious plasma current path modifies the optimal shape of the plasma centerpost. Moreover, as the plasma torus is produced and sustained, in absence of any applied inductive electric field, by the inner plasma centerpost through magnetic reconnections [Taylor J B and Turner M F 1989 Nucl.Fusion 29 219], it is required as well that spurious current paths do not surround the torus on its outboard, in order not to lower the efficiency of the magnetic reconnections that maintain the plasma torus at the expense of the plasma centerpost. Boundary conditions have been corrected,up to the point that the first sustainment in steady state has been achieved for the combined plasma.展开更多
This paper deals with wave propagation and power coupling in blue-core helicon plasma driven by various antennas and frequencies.It is found that compared to non-blue-core mode,for blue-core mode,the wave can propagat...This paper deals with wave propagation and power coupling in blue-core helicon plasma driven by various antennas and frequencies.It is found that compared to non-blue-core mode,for blue-core mode,the wave can propagate in the core region,and it decays sharply outside the core.The power absorption is lower and steeper in radius for blue-core mode.Regarding the effects of antenna geometry for blue-core mode,it shows that half helix antenna yields the strongest wave field and power absorption,while loop antenna yields the lowest.Moreover,near axis,for antennas with m=+1,the wave field increases with axial distance.In the core region,the wave number approaches to a saturation value at much lower frequency for non-blue-core mode compared to blue-core mode.The total loading resistance is much lower for blue-core mode.These findings are valuable to understanding the physics of blue-core helicon discharge and optimizing the experimental performance of blue-core helicon plasma sources for applications such as space propulsion and material treatment.展开更多
A remote plasma,also referred to as a plasma plume(diffuse or filamentary),is normally formed downstream of an atmospheric pressure plasma jet.In this study,a diffuse plume is formed by increasing the bias voltage(U_(...A remote plasma,also referred to as a plasma plume(diffuse or filamentary),is normally formed downstream of an atmospheric pressure plasma jet.In this study,a diffuse plume is formed by increasing the bias voltage(U_(b))applied to the downstream electrode of an argon plasma jet excited by a negatively pulsed voltage.The results indicate that the plume is filamentary when U_(b)is low,which transits to the diffuse plume with increasing U_(b).The discharge initiated at the rising edge of the pulsed voltage is attributed to the diffuse plume,while that at the falling edge contributes to the filament in the plume.For the diffuse plume,the discharge intensity decreases with the increasing oxygen content(C_o).Fast photography reveals that the diffuse plume results from a negative streamer,which has a dark region near the nozzle with C_o=0%.However,the dark region is absent with C_o=0.5%.From the optical emission spectrum,the electron density,electron excitation temperature,gas temperature,and oxygen atom concentration are investigated.展开更多
文摘The Landau damping behavior in a cylindrical inhomogeneous warm magnetized plasma waveguide has been studied.The radial inhomogeneity for different characteristic lengths(L0) with strong spatial dispersion has been taken into account.The analyses have been considered for two limits ωce 〈 ωpe and ωce 〉 ωpe. Due to the radial inhomogeneity of the plasma, all essential equations for studying the Landau damping are calculated in the Bessel–Furrier and differential Bessel–Furrier expansions. The dependence of Landau damping on the inhomogeneity, temperature and external magnetic field for electrostatic modes is scrutinized and described in detail through numerical calculations. The associated numerical results are presented and discussed.
基金Project supported by the National Natural Science Foundation of China (Grant No. 10963002)the International S & T Cooperation Program of China and Jiangxi Province (Grant No. 2009DFA02320)+1 种基金the Program for Innovative Research Team of Nanchang Universitythe National Basic Research Program of China (Grant No. 2010CB635112)
文摘The generalized dispersion equation for longitudinal oscillation in an unmagnetized, collisionless, isotropic and relativistic plasma is derived in the context of nonextensive q-distribution. An analytical expression for the Landau damping is obtained in an ultra-relativistic regime, which is related to q-parameter. In the limit q →1, the result based on the relativistic Maxwellian distribution is recovered. It is shown that the interactions between the wave and particles are stronger and the waves are more strongly damped for lower values of q-parameter. The results are explained by the increased number of superthermal particles or low velocity particles contained in the plasma with the nonextensive distribution.
文摘The damping decrement of Landau damping and the effect of thermal velocity on the frequency spectrum of a propagating wave in a bounded plasma column are investigated.The magnetized plasma column partially filling a cylindrical metallic tube is considered to be collisionless and non-degenerate.The Landau damping is due to the thermal motion of charge carriers and appears whenever the phase velocity of the plasma waves exceeds the thermal velocity of carriers.The analysis is based on a self-consistent kinetic theory and the solutions of the wave equation in a cylindrical plasma waveguide are presented using Vlasov and Maxwell equations.The hybrid mode dispersion equation for the cylindrical plasma waveguide is obtained through the application of appropriate boundary conditions to the plasma-vacuum interface.The dependence of Landau damping on plasma parameters and the effects of the metallic tube boundary on the dispersion characteristics of plasma and waveguide modes are investigated in detail through numerical calculations.
基金supported by National Natural Science Foundation of China(Nos.91026005,11275156,11047010,61162017)
文摘The solitary waves of a viscous plasma confined in a cuboid under the three types of boundary condition are theoretically investigated in the present paper.By introducing a threedimensional rectangular geometry and employing the reductive perturbation theory,a quasi-Kd V equation is derived in the viscous plasma and a damping solitary wave is obtained.It is found that the damping rate increases as the viscosity coefficient increases,or increases as the length and width of the rectangle decrease,for all kinds of boundary condition.Nevertheless,the magnitude of the damping rate is dominated by the types of boundary condition.We thus observe the existence of a damping solitary wave from the fact that its amplitude disappears rapidly for a → 0and b → 0,or ν→ +∞.
文摘The dispersion of Langmuir wave(LW)in an unmagnetized collisionless plasma with regularized Kappa distributed electrons is investigated from the kinetic theory.The frequency and damping rate of LW are analyzed for the parameters relating to the source region of a typeⅢsolar radio burst.It is found that the linear behavior of LW is greatly modified by the suprathermal indexκand the exponential cutoff parameterα.In the regionκ<1.5,the damping rate of LW will be much larger than the one with Maxwellian distributed electrons.Hence,the nonlinear process of LW in lowκregion may exhibit different properties in comparison with the one in largeκregion.
基金the grant No. 101/ORIC/17 from the Government College University, Lahore, Pakistan
文摘The dispersion relations of parallel propagating modes(Langmuir mode, right and left handed circular polarized waves) in the weak magnetic field limit |ω-k·v| 〉〉 ? are considered for ultra-relativistic arbitrary degenerate electron plasma. The results are presented in terms of moments of Fermi-Dirac distribution. The increase in the electron equilibrium number density from negative large(weakly degenerate) to positive large(highly degenerate) values of μ/Te is observed(where μ is the electron chemical potential and Te is the electron thermal energy). As a result, shifting of the cutoff points in all the real dispersion branches towards the higher values and increasing in the band gap between unmagnetized longitudinal and transverse modes in k-space are examined. Also, the suppression of the weak magnetic field effects in weakly magnetized right handed and left handed circular polarized waves and a decrease in the longitudinal and transverse screening effects are observed in the graphical patterns due to an increase in the equilibrium number density.
文摘The observations of in-situ spacecraft mission in the magnetosheath and a region of thermalized subsonic plasma behind the bow shock reveal a non-linear behaviour of plasma waves. The study of waves and optics in Physics has given the understanding of the effect of many waves coming together to form a wave field or wave packet. The common aspect of such study shows that two or more waves can superimpose constructively or destructively. The sudden high magnetic field data in the magnetosheath displays such possibility of superposition of waves. In this paper, we use the empirical mode decomposition (EMD) and Hilbert transform (HT) techniques to determine the instantaneous frequencies of low frequency plasma waves in the magnetosheath. Our analysis has shown that the turbulent behavior of magnetic field in the magnetosheath within the selected period is due to superposition of waves.
基金supported by the National Key R&D Program of China (No. 2016YFA0401100)National Natural Science Foundation of China (Nos. 12175154, 11875092, and 12005149)the Natural Science Foundation of Top Talent of Shenzhen Technology University (Nos. 2019010801001 and 2019020801001)。
文摘Evolution of an electrostatic plasma wave driven by a low-density ultra-relativistic electron beam in dense inhomogeneous plasma is considered. In particular, the wavelength variation as observed at fixed locations in the plasma is analyzed in terms of the wave characteristics. It is shown that for a negative density gradient, the observed local wavelength decreases monotonically with time, but for a positive density gradient, it first increases and then decreases with time, accompanied by reversal of the wave phase. However, in both cases the local wavelength eventually decreases with time since Landau damping becomes significant as the wavelength becomes of the order of the plasma Debye length. Results from particle-in-cell simulations agree well with theoretical analyses of the wavelength variation.
文摘Plasma sprayed ceramic coatings are successfully used in many industrial applications,where high wear and corrosion resistance with thermal insulation are required.In this work,empirical relationships were developed to predict the porosity and corrosion rate of alumina coatings by incorporating independently controllable atmospheric plasma spray operational parameters(input power,stand-off distance and powder feed rate)using response surface methodology(RSM).A central composite rotatable design with three factors and five levels was chosen to minimize the number of experimental conditions.Within the scope of the design space,the input power and the stand-off distance appeared to be the most significant two parameters affecting the responses among the three investigated process parameters.A linear regression relationship was also established between porosity and corrosion rate of the alumina coatings.Further,sensitivity analysis was carried out and compared with the relative impact of three process parameters on porosity level and corrosion rate to verify the measurement errors on the values of the uncertainty in estimated parameters.
文摘Analysis of Incoherent Scatter Radar(ISR)data collected during an experiment involving alternating O/X mode pumping reveals that the high-frequency enhanced ion line(HFIL)and plasma line(HFPL)did not appear immediately after the onset of pumping,but were delayed by a few seconds.By examining the initial behaviors of the ion line,plasma line,and electron temperature,as well as ionosphere conditions,we find that(1)the HFIL and HFPL were delayed not only in the X mode pumping but also in the O mode pumping and(2)the HFIL was not observed prior to enhancement of the electron temperature.Our analysis suggests that(1)leakage of the X mode to the O mode pumping may not be ignored and(2)spatiotemporal uncertainties and spatiotemporal variations in the profiles of ion mass and electron density may have played important roles in the apparent failure of the Bragg condition to apply;(3)nevertheless,the absence of parametric decay instability(PDI)cannot be ruled out,due to our inability to match conditions caused by the spatiotemporal uncertainties.
基金supported by the National Key Research&Development Program of China,Nos.2021YFC2501205(to YC),2022YFC24069004(to JL)the STI2030-Major Project,Nos.2021ZD0201101(to YC),2022ZD0211800(to YH)+2 种基金the National Natural Science Foundation of China(Major International Joint Research Project),No.82020108013(to YH)the Sino-German Center for Research Promotion,No.M-0759(to YH)a grant from Beijing Municipal Science&Technology Commission(Beijing Brain Initiative),No.Z201100005520018(to JL)。
文摘Several promising plasma biomarker proteins,such as amyloid-β(Aβ),tau,neurofilament light chain,and glial fibrillary acidic protein,are widely used for the diagnosis of neurodegenerative diseases.However,little is known about the long-term stability of these biomarker proteins in plasma samples stored at-80°C.We aimed to explore how storage time would affect the diagnostic accuracy of these biomarkers using a large cohort.Plasma samples from 229 cognitively unimpaired individuals,encompassing healthy controls and those experiencing subjective cognitive decline,as well as 99 patients with cognitive impairment,comprising those with mild cognitive impairment and dementia,were acquired from the Sino Longitudinal Study on Cognitive Decline project.These samples were stored at-80°C for up to 6 years before being used in this study.Our results showed that plasma levels of Aβ42,Aβ40,neurofilament light chain,and glial fibrillary acidic protein were not significantly correlated with sample storage time.However,the level of total tau showed a negative correlation with sample storage time.Notably,in individuals without cognitive impairment,plasma levels of total protein and tau phosphorylated protein threonine 181(p-tau181)also showed a negative correlation with sample storage time.This was not observed in individuals with cognitive impairment.Consequently,we speculate that the diagnostic accuracy of plasma p-tau181 and the p-tau181 to total tau ratio may be influenced by sample storage time.Therefore,caution is advised when using these plasma biomarkers for the identification of neurodegenerative diseases,such as Alzheimer's disease.Furthermore,in cohort studies,it is important to consider the impact of storage time on the overall results.
基金supported by the fund from ShenyangMint Company Limited(No.20220056)Senior Talent Foundation of Jiangsu University(No.19JDG022)Taizhou City Double Innovation and Entrepreneurship Talent Program(No.Taizhou Human Resources Office[2022]No.22).
文摘In this research,we present the pure open multi-processing(OpenMP),pure message passing interface(MPI),and hybrid MPI/OpenMP parallel solvers within the dynamic explicit central difference algorithm for the coining process to address the challenge of capturing fine relief features of approximately 50 microns.Achieving such precision demands the utilization of at least 7 million tetrahedron elements,surpassing the capabilities of traditional serial programs previously developed.To mitigate data races when calculating internal forces,intermediate arrays are introduced within the OpenMP directive.This helps ensure proper synchronization and avoid conflicts during parallel execution.Additionally,in the MPI implementation,the coins are partitioned into the desired number of regions.This division allows for efficient distribution of computational tasks across multiple processes.Numerical simulation examples are conducted to compare the three solvers with serial programs,evaluating correctness,acceleration ratio,and parallel efficiency.The results reveal a relative error of approximately 0.3%in forming force among the parallel and serial solvers,while the predicted insufficient material zones align with experimental observations.Additionally,speedup ratio and parallel efficiency are assessed for the coining process simulation.The pureMPI parallel solver achieves a maximum acceleration of 9.5 on a single computer(utilizing 12 cores)and the hybrid solver exhibits a speedup ratio of 136 in a cluster(using 6 compute nodes and 12 cores per compute node),showing the strong scalability of the hybrid MPI/OpenMP programming model.This approach effectively meets the simulation requirements for commemorative coins with intricate relief patterns.
基金financially supported by National Natural Science Foundation of China(Nos.12075049 and 11935005)。
文摘The dual cylindrical inductively coupled plasma source,compared to the conventional structure of inductively coupled plasma source,can significantly improve the uniformity of plasma.It has an enhanced potential for application in processes,such as etching and ashing.A uniform plasma can be obtained by allowing the remote plasma from the upper chamber modulate the main plasma generated in the lower chamber.In this study,a fluid model was employed to investigate a dual cylindrical inductively coupled Ar/O_(2)discharge.The effects of external parameters on electron density,electron temperature,O atomic density,and plasma uniformity in the main chamber were studied,and the reasons were analyzed.The results of this study show that remote power can control the plasma uniformity and increase the plasma density in the main chamber.As the remote power increased,plasma uniformity improved initially and then deteriorated.The main power affected the plasma density at the edge of the main chamber and can modulate the plasma density in the main chamber.The gas pressure affected both the uniformity and density of the plasma.As the gas pressure increased,the plasma uniformity deteriorated,but the free radical density improved.
文摘In astrophysics, the boundary conditions for plasma phenomena are provided by nature and the astronomer faces the problem of understanding them from a variety of observations [Hester J J et al 1996 Astrophys. J. 456 225], on the other hand, in laboratory plasma experiments the electromagnetic boundary conditions become a major problem in the set-up of the machine that produces the plasma, an issue that has to be investigated step by step and to be modified and adapted with great patience, in particular in the case of an innovative plasma confinement experiment. The PROTO-SPHERA machine [Alladio F et al 2006 Nucl. Fusion 46 S613] is a magnetic confinement experiment, that emulates in the laboratory the jet + torus plasma configurations often observed in astrophysics: an inner magnetized jet of plasma centered on the(approximate) axis of symmetry and surrounded by a magnetized plasma torus orthogonal to this jet. The PROTO-SPHERA plasma is simply connected, i.e., no metal current conducting rod is linked to the plasma torus, while instead it is the inner magnetized plasma jet(in the following always called the plasma centerpost) that is linked to the torus. It is mandatory that no spurious plasma current path modifies the optimal shape of the plasma centerpost. Moreover, as the plasma torus is produced and sustained, in absence of any applied inductive electric field, by the inner plasma centerpost through magnetic reconnections [Taylor J B and Turner M F 1989 Nucl.Fusion 29 219], it is required as well that spurious current paths do not surround the torus on its outboard, in order not to lower the efficiency of the magnetic reconnections that maintain the plasma torus at the expense of the plasma centerpost. Boundary conditions have been corrected,up to the point that the first sustainment in steady state has been achieved for the combined plasma.
基金Project supported by the National Natural Science Foundation of China(Grant No.92271113)the Fundamental Research Funds for the Central Universities(Grant No.2022CDJQY-003)+1 种基金Chongqing Entrepreneurship and Innovation Support Program for Overseas Returnees(Grant No.CX2022004)the Fund from Shanghai Engineering Research Center of Space Engine(Grant No.17DZ2280800).
文摘This paper deals with wave propagation and power coupling in blue-core helicon plasma driven by various antennas and frequencies.It is found that compared to non-blue-core mode,for blue-core mode,the wave can propagate in the core region,and it decays sharply outside the core.The power absorption is lower and steeper in radius for blue-core mode.Regarding the effects of antenna geometry for blue-core mode,it shows that half helix antenna yields the strongest wave field and power absorption,while loop antenna yields the lowest.Moreover,near axis,for antennas with m=+1,the wave field increases with axial distance.In the core region,the wave number approaches to a saturation value at much lower frequency for non-blue-core mode compared to blue-core mode.The total loading resistance is much lower for blue-core mode.These findings are valuable to understanding the physics of blue-core helicon discharge and optimizing the experimental performance of blue-core helicon plasma sources for applications such as space propulsion and material treatment.
基金supported by National Natural Science Foundation of China(Nos.12375250,11875121,51977057 and 11805013)the Natural Science Foundation of Hebei Province(Nos.A2020201025 and A2022201036)+3 种基金Hebei Province Optoelectronic Information Materials Laboratory Performance Subsidy Fund Project(No.22567634H)Funds for Distinguished Young Scientists of Hebei Province(No.A2012201045)the Natural Science Interdisciplinary Research Program of Hebei University(Nos.DXK201908 and DXK202011)the Post-graduate’s Innovation Fund Project of Hebei University(No.HBU2022bs004)。
文摘A remote plasma,also referred to as a plasma plume(diffuse or filamentary),is normally formed downstream of an atmospheric pressure plasma jet.In this study,a diffuse plume is formed by increasing the bias voltage(U_(b))applied to the downstream electrode of an argon plasma jet excited by a negatively pulsed voltage.The results indicate that the plume is filamentary when U_(b)is low,which transits to the diffuse plume with increasing U_(b).The discharge initiated at the rising edge of the pulsed voltage is attributed to the diffuse plume,while that at the falling edge contributes to the filament in the plume.For the diffuse plume,the discharge intensity decreases with the increasing oxygen content(C_o).Fast photography reveals that the diffuse plume results from a negative streamer,which has a dark region near the nozzle with C_o=0%.However,the dark region is absent with C_o=0.5%.From the optical emission spectrum,the electron density,electron excitation temperature,gas temperature,and oxygen atom concentration are investigated.