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新的糖肽类抗生素泰可匹宁 被引量:1
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作者 潘启超 《中国新药杂志》 CAS CSCD 1996年第6期407-410,共4页
泰可匹宁(teicoplanin)为放线菌培养液的糖肽类抗生素,其结构与万古霉素相似。活性等于或优于万古霉素,主要抑制G+菌及对甲氧苯青霉素无效的金葡菌(MRSA),对G+厌氧菌如难辨梭菌亦有效。作用机理为抑制细菌细... 泰可匹宁(teicoplanin)为放线菌培养液的糖肽类抗生素,其结构与万古霉素相似。活性等于或优于万古霉素,主要抑制G+菌及对甲氧苯青霉素无效的金葡菌(MRSA),对G+厌氧菌如难辨梭菌亦有效。作用机理为抑制细菌细胞壁合成。清除半衰期长达47h,可每天给药1次。不良反应较万古霉素少,肾毒性亦较少。主要用于对青霉素、头孢菌素有抗药性细菌,包括MRSA的感染及难辨梭状杆菌所致的伪膜性结肠炎。 展开更多
关键词 泰可匹宁 mrsn 药理
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Application of Taguchi’s Orthogonal Array in Multi Response Optimization of NO<sub>x</sub>Emission of Crude Rice Bran Oil Methyl Ester Blend as a CI Engine Fuel
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作者 Subramani Saravanan Govindan Nagarajan Santhanam Sampath 《Open Journal of Optimization》 2012年第2期25-33,共9页
In this work an attempt was made to minimize the NOx emission of a crude rice bran oil methyl ester (CRBME) blend with less sacrifice on smoke density and brake thermal efficiency. Three factors namely fuel injection ... In this work an attempt was made to minimize the NOx emission of a crude rice bran oil methyl ester (CRBME) blend with less sacrifice on smoke density and brake thermal efficiency. Three factors namely fuel injection timing, percentage EGR and fuel injection pressure were chosen as the influencing factors for the set objective. Experiments were designed by employing design of experiments method and Taguchi’s L9 orthogonal array was used to test the engine. MRSN ratio was calculated for the response variables and the optimum combination level of factors was obtained simultaneously using Taguchi’s parametric design. ANOVA was employed to analyze the variance of MRSN and the most influencing factor for the set objective was taken from the ANOVA table. Obtained combination was confirmed experimentally and significant improvement was observed in the response variables. 展开更多
关键词 Diesel Engine EMISSION CRUDE Rice BRAN Oil Biodiesel Taguchi’s Orthogonal Array mrsn DOE
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