目的了解HIV感染者/AIDS病人(people living with HIV/AIDS,PLWHAS)的生存质量现状及其影响因素。方法采用简体中文版MOS-HIV量表评价371例PLWHAS的生存质量现状,同时调查可能影响其生存质量的人口学特征和HIV感染相关情况。采用t检验...目的了解HIV感染者/AIDS病人(people living with HIV/AIDS,PLWHAS)的生存质量现状及其影响因素。方法采用简体中文版MOS-HIV量表评价371例PLWHAS的生存质量现状,同时调查可能影响其生存质量的人口学特征和HIV感染相关情况。采用t检验、方差分析和多元线性回归模型进行统计分析。结果生存质量得分:心理健康总分为(46.60±10.45)分,生理健康总分为(51.14±9.28)分。单因素分析结果显示:年龄、文化程度、职业等因素,与PLWHAS的生存质量各个领域有关(P<0.05)。多元线性回归分析结果显示:年龄、收入、文化程度和感染途径,是影响PLWHAS生存质量的主要因素。结论年龄、收入、文化程度和感染途径等,在不同方面影响着PLWHAS的生存质量。重点关注老年、收入较低、文化程度较低者的生存质量,对提高该人群生存质量有重要意义。展开更多
目的:了解云南省陇川县艾滋病病毒感染者/艾滋病病人(People Living with HIV/AIDS,PLWHA)的生存质量及其影响因素,为今后的深入研究提供依据。方法:采用横断面调查方法,对陇川县PLWHA采用一般情况调查问卷、MOS-HIV生存质量量表进行问...目的:了解云南省陇川县艾滋病病毒感染者/艾滋病病人(People Living with HIV/AIDS,PLWHA)的生存质量及其影响因素,为今后的深入研究提供依据。方法:采用横断面调查方法,对陇川县PLWHA采用一般情况调查问卷、MOS-HIV生存质量量表进行问卷调查。结果:PLWHA生存质量的躯体健康总分为(49.12±11.14)分,精神状况得分为(43.40±10.05)分;经抗病毒治疗组疼痛、精力或疲劳得分均高于未治疗组。女性总体健康感觉(57.88±24.78)分,高于男性的(44.13±26.85)分;女性的角色功能纬度得分和躯体健康总分分别为(72.73±45.23)分和(53.18±9.18)分,均高于男性。经过多元逐步回归分析,少数民族躯体健康总分低于汉族;并发症数越多,躯体健康总分越低。结论:抗病毒治疗能提高PLWHA的生存质量;性别、民族、治疗情况可能是PLWHA生存质量的影响因素。展开更多
Background::HIV/AIDS has transformed into a chronic controllable but not yet curable infectious disease as other chronic diseases to some extent.The additional of so called fourth 90%that included the improved health-...Background::HIV/AIDS has transformed into a chronic controllable but not yet curable infectious disease as other chronic diseases to some extent.The additional of so called fourth 90%that included the improved health-related quality of life(HRQoL)for people living with HIV(PLWHIV)required solutions beyond antiretroviral therapy and viral load suppression.This study will explore the role of personality,social economic and prevention strategy effection on HRQoL among people living with HIV/AIDS.Methods::A cross-sectional study was conducted among PLWHIV aged more than 16 years old in the 10 municipalities in Yunnan Province,China from October 2019 to May 2020,enrolling total 1997 participants.Individual-level HRQoL data were measured by 12-item Short Form Health Survey(SF-12)and EuroQol Five Dimensions Questionnaire(EQ-5D-5L).We assembled municipal-level data about social economic from Yunnan Statistical Yearbook in 2020 and strategy practice information from the self-evaluation system.We used the principal component analysis to build the social economic and strategy effect on each area respectively and one-way ANOVA was used to perform univariate analysis to identify the predictors with significant differences.Finally we used multi-level model(MLM)to explore the personality,social economic and strategy effects in health-related quality of life among PLWHIV.Results::The global score for quality of life measured using EQ-5D-5L had an estimated mean score(standard deviation,SD)of 0.901±0.146.The HRQoL score measured using PCS-12 had an estimated mean score(SD)of 46.62±8.55.The mean MCS-12 score(SD)was estimated to be 47.80±9.71.The area-level predictors explained a proportion of 13.6-17.2%for the between-area variation of the HRQoL scores,regardless of the total HRQoL,physical component and mental component.The impacts of stigma(P<0.01),social support(P<0.001),anxiety(P<0.001),depression(P<0.05)and social economic status(P<0.05)on HRQoL at the individual-level were significantly different.The plots visualized the impact of individual-level factors on a respondent’s HRQoL was modified by the area-level characteristics.Conclusions::The study identified the possible strategy determinant of individual HRQoL of PLWHIV and also the area effect on HRQoL.Stigma,social support,anxiety,depression and social economic status were the individual-level determinants on HRQoL.These could be a valuable resource for evaluating the overall health of the areas and help improve local decision making.展开更多
目的:分析人类免疫缺陷病毒(HIV)感染者/艾滋病(AIDS)患者伴海洛因成瘾者(以下简称HIV/AIDS伴海洛因成瘾者)心理状况以及健康相关生命质量(health related quality of life,HRQOL)评分,并统计HRQOL的影响因素及影响因素主次关系。方法:...目的:分析人类免疫缺陷病毒(HIV)感染者/艾滋病(AIDS)患者伴海洛因成瘾者(以下简称HIV/AIDS伴海洛因成瘾者)心理状况以及健康相关生命质量(health related quality of life,HRQOL)评分,并统计HRQOL的影响因素及影响因素主次关系。方法:使用抑郁自评量表(skelf-rating depression scale,SDS)评估HIV/AIDS伴海洛因成瘾患者心理状况,使用生活质量评价量表(short form 36 questionnaire,SF-36)测量HIV/AIDS伴海洛因成瘾患者的HRQOL评分,采用Pearson相关分析法分析HRQOL和SDS评分之间相关性,同时使用单因素方差分析及多元逐步线性回归统计对HRQOL的影响因素进行分析。结果:SDS评分结果显示抑郁症状109例(92.4%),其中轻度抑郁35例(29.6%),中度抑郁48例(40.6%),重度抑郁26例(22.2%)。平均HRQOL分数为(483.96±125.85)分,无症状HIV感染者HRQOL总分高于AIDS患者(P<0.05),且HRQOL与SDS评分呈负相关(R=-0.476,P=0.002)。统计结果显示锻炼、抗HIV治疗、年龄、机会感染、并发肿瘤、文化程度、婚姻状况、美沙酮治疗、居住地可影响HRQOL评分。其中HRQOL总分与年龄、机会感染、并发肿瘤、居住地因素呈负相关(P<0.05),与锻炼情况、抗HIV和美沙酮治疗、文化程度、婚姻状况因素呈现正相关(P<0.05)。结论:HIV/AIDS伴海洛因依赖者普遍伴有抑郁症状,HRQOL较差。在治疗中应重视大龄、低学历、农村居民、并发机会感染和肿瘤患者以及无配偶者的防治。展开更多
文摘目的了解HIV感染者/AIDS病人(people living with HIV/AIDS,PLWHAS)的生存质量现状及其影响因素。方法采用简体中文版MOS-HIV量表评价371例PLWHAS的生存质量现状,同时调查可能影响其生存质量的人口学特征和HIV感染相关情况。采用t检验、方差分析和多元线性回归模型进行统计分析。结果生存质量得分:心理健康总分为(46.60±10.45)分,生理健康总分为(51.14±9.28)分。单因素分析结果显示:年龄、文化程度、职业等因素,与PLWHAS的生存质量各个领域有关(P<0.05)。多元线性回归分析结果显示:年龄、收入、文化程度和感染途径,是影响PLWHAS生存质量的主要因素。结论年龄、收入、文化程度和感染途径等,在不同方面影响着PLWHAS的生存质量。重点关注老年、收入较低、文化程度较低者的生存质量,对提高该人群生存质量有重要意义。
文摘目的:了解云南省陇川县艾滋病病毒感染者/艾滋病病人(People Living with HIV/AIDS,PLWHA)的生存质量及其影响因素,为今后的深入研究提供依据。方法:采用横断面调查方法,对陇川县PLWHA采用一般情况调查问卷、MOS-HIV生存质量量表进行问卷调查。结果:PLWHA生存质量的躯体健康总分为(49.12±11.14)分,精神状况得分为(43.40±10.05)分;经抗病毒治疗组疼痛、精力或疲劳得分均高于未治疗组。女性总体健康感觉(57.88±24.78)分,高于男性的(44.13±26.85)分;女性的角色功能纬度得分和躯体健康总分分别为(72.73±45.23)分和(53.18±9.18)分,均高于男性。经过多元逐步回归分析,少数民族躯体健康总分低于汉族;并发症数越多,躯体健康总分越低。结论:抗病毒治疗能提高PLWHA的生存质量;性别、民族、治疗情况可能是PLWHA生存质量的影响因素。
基金Our study was supported by National Nature Science Foundation of China(No.71904166)Yunnan high-level medical cultivation programme(No.H-2018103)13th Five-year National S&T Major Project for Comprehensive Pilots(No.2018ZX10715006).
文摘Background::HIV/AIDS has transformed into a chronic controllable but not yet curable infectious disease as other chronic diseases to some extent.The additional of so called fourth 90%that included the improved health-related quality of life(HRQoL)for people living with HIV(PLWHIV)required solutions beyond antiretroviral therapy and viral load suppression.This study will explore the role of personality,social economic and prevention strategy effection on HRQoL among people living with HIV/AIDS.Methods::A cross-sectional study was conducted among PLWHIV aged more than 16 years old in the 10 municipalities in Yunnan Province,China from October 2019 to May 2020,enrolling total 1997 participants.Individual-level HRQoL data were measured by 12-item Short Form Health Survey(SF-12)and EuroQol Five Dimensions Questionnaire(EQ-5D-5L).We assembled municipal-level data about social economic from Yunnan Statistical Yearbook in 2020 and strategy practice information from the self-evaluation system.We used the principal component analysis to build the social economic and strategy effect on each area respectively and one-way ANOVA was used to perform univariate analysis to identify the predictors with significant differences.Finally we used multi-level model(MLM)to explore the personality,social economic and strategy effects in health-related quality of life among PLWHIV.Results::The global score for quality of life measured using EQ-5D-5L had an estimated mean score(standard deviation,SD)of 0.901±0.146.The HRQoL score measured using PCS-12 had an estimated mean score(SD)of 46.62±8.55.The mean MCS-12 score(SD)was estimated to be 47.80±9.71.The area-level predictors explained a proportion of 13.6-17.2%for the between-area variation of the HRQoL scores,regardless of the total HRQoL,physical component and mental component.The impacts of stigma(P<0.01),social support(P<0.001),anxiety(P<0.001),depression(P<0.05)and social economic status(P<0.05)on HRQoL at the individual-level were significantly different.The plots visualized the impact of individual-level factors on a respondent’s HRQoL was modified by the area-level characteristics.Conclusions::The study identified the possible strategy determinant of individual HRQoL of PLWHIV and also the area effect on HRQoL.Stigma,social support,anxiety,depression and social economic status were the individual-level determinants on HRQoL.These could be a valuable resource for evaluating the overall health of the areas and help improve local decision making.
文摘目的:分析人类免疫缺陷病毒(HIV)感染者/艾滋病(AIDS)患者伴海洛因成瘾者(以下简称HIV/AIDS伴海洛因成瘾者)心理状况以及健康相关生命质量(health related quality of life,HRQOL)评分,并统计HRQOL的影响因素及影响因素主次关系。方法:使用抑郁自评量表(skelf-rating depression scale,SDS)评估HIV/AIDS伴海洛因成瘾患者心理状况,使用生活质量评价量表(short form 36 questionnaire,SF-36)测量HIV/AIDS伴海洛因成瘾患者的HRQOL评分,采用Pearson相关分析法分析HRQOL和SDS评分之间相关性,同时使用单因素方差分析及多元逐步线性回归统计对HRQOL的影响因素进行分析。结果:SDS评分结果显示抑郁症状109例(92.4%),其中轻度抑郁35例(29.6%),中度抑郁48例(40.6%),重度抑郁26例(22.2%)。平均HRQOL分数为(483.96±125.85)分,无症状HIV感染者HRQOL总分高于AIDS患者(P<0.05),且HRQOL与SDS评分呈负相关(R=-0.476,P=0.002)。统计结果显示锻炼、抗HIV治疗、年龄、机会感染、并发肿瘤、文化程度、婚姻状况、美沙酮治疗、居住地可影响HRQOL评分。其中HRQOL总分与年龄、机会感染、并发肿瘤、居住地因素呈负相关(P<0.05),与锻炼情况、抗HIV和美沙酮治疗、文化程度、婚姻状况因素呈现正相关(P<0.05)。结论:HIV/AIDS伴海洛因依赖者普遍伴有抑郁症状,HRQOL较差。在治疗中应重视大龄、低学历、农村居民、并发机会感染和肿瘤患者以及无配偶者的防治。
