期刊文献+
共找到1篇文章
< 1 >
每页显示 20 50 100
Macular thickness as a predictor of loss of visual sensitivity in ethambutol-induced optic neuropathy 被引量:5
1
作者 Chun-xia Peng Ai-di Zhang +4 位作者 Bing Chen Bing-jian Yang Qiu-hong Wang Mo Yang Shi-hui Wei 《Neural Regeneration Research》 SCIE CAS CSCD 2016年第3期469-475,共7页
Ethambutol is a common cause of drug-related optic neuropathy.Prediction of the onset of ethambutol-induced optic neuropathy and consequent drug withdrawal may be an effective method to stop visual loss.Previous studi... Ethambutol is a common cause of drug-related optic neuropathy.Prediction of the onset of ethambutol-induced optic neuropathy and consequent drug withdrawal may be an effective method to stop visual loss.Previous studies have shown that structural injury to the optic nerve occurred earlier than the damage to visual function.Therefore,we decided to detect structural biomarkers marking visual field loss in early stage ethambutol-induced optic neuropathy.The thickness of peripapillary retinal nerve fiber layer,macular thickness and visual sensitivity loss would be observed in 11 ethambutol-induced optic neuropathy patients(22 eyes) using optical coherence tomography.Twenty-four healthy age-and sex-matched participants(48 eyes) were used as controls.Results demonstrated that the temporal peripapillary retinal nerve fiber layer thickness and average macular thickness were thinner in patients with ethambutol-induced optic neuropathy compared with healthy controls.The average macular thickness was strongly positively correlated with central visual sensitivity loss(r2=0.878,P=0.000).These findings suggest that optical coherence tomography can be used to efficiently screen patients.Macular thickness loss could be a potential factor for predicting the onset of ethambutol-induced optic neuropathy. 展开更多
关键词 nerve regeneration ethambutol-induced optic neuropathy optical coherence tomography peripapillary retinal nerve fiber layer ethambutol macular thickness visual sensitivity neural regeneration
下载PDF
上一页 1 下一页 到第
使用帮助 返回顶部