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Web GIS Human-Machine Interactive Interface Design with VISI
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作者 XIONG Lan HU Hongliang +2 位作者 DU Qingyun HUANG Maojun WANG Mingjun 《Geo-Spatial Information Science》 2008年第1期66-70,共5页
The fusion of VlSI (visual identity system Internet), digital maps and Web GIS is presented. Web GIS interface interactive design with VISI needs to consider more new factors. VISI can provide the design principle, ... The fusion of VlSI (visual identity system Internet), digital maps and Web GIS is presented. Web GIS interface interactive design with VISI needs to consider more new factors. VISI can provide the design principle, elements and contents for the Web GIS. The design of the Wuhan Bus Search System is fulfilled to confirm the validity and practicability of the fusion. 展开更多
关键词 Web GIS human-machine interactive interface design VISI
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Research on the Man-machine Interactive Environment VR and the Applications on Vocational Education and Training under the Perspective of Interactivity
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作者 Xiaoyi Huo 《International Journal of Technology Management》 2016年第7期39-41,共3页
In this paper, we conduct research on the man-machine interactive environment VR and the applications on vocational educationand training under the perspective of interactivity. With the increase in the general standa... In this paper, we conduct research on the man-machine interactive environment VR and the applications on vocational educationand training under the perspective of interactivity. With the increase in the general standard of social knowledge level and competition intensifi es,more and more people have a goal to build a lifelong learning system, according to their own hobbies, work and the needs of the marketcompetition. Under this condition, the vocational education is becoming more and more essential. This paper integrates the VR and man-machineinteractive concept to propose the new education paradigm that is innovative. 展开更多
关键词 man-machine Environment VR Vocational Education Perspective of interactivity.
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Human-machine interactive streaming anomaly detection by online self-adaptive forest
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作者 Qingyang LI Zhiwen YU +1 位作者 Huang XU Bin GUO 《Frontiers of Computer Science》 SCIE EI CSCD 2023年第2期145-156,共12页
At nomaly detectors are used to distinguish differences between normal and abnormal data,which are usually implemented by evaluating and ranking the anomaly scores of each instance.A static unsupervised streaming anom... At nomaly detectors are used to distinguish differences between normal and abnormal data,which are usually implemented by evaluating and ranking the anomaly scores of each instance.A static unsupervised streaming anomaly detector is difficult to dynamically adjust anomaly score calculation.In real scenarios,anomaly detection often needs to be regulated by human feedback,which benefits adjusting anomaly detectors.In this paper,we propose a human-machine interactive streaming anomaly detection method,named ISPForest,which can be adaptively updated online under the guidance of human feedback.In particular,the feedback will be used to adjust the anomaly score calculation and structure of the detector,ideally attaining more accurate anomaly scores in the future.Our main contribution is to improve the tree-based streaming anomaly detection model that can be updated online from perspectives of anomaly score calculation and model structure.Our approach is instantiated for the powerful class of tree-based streaming anomaly detectors,and we conduct experiments on a range of benchmark datasets.The results demonstrate that the utility of incorporating feedback can improve the performance of anomaly detectors with a few human efforts. 展开更多
关键词 anomaly detection human-machine interaction human feedback random space tree ensemble method
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Designing interactive glazing through an engineering psychology approach:Six augmented reality scenarios that envision future car human-machine interface
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作者 Wei LIU Yancong ZHU +5 位作者 Ruonan HUANG Takumi OHASHI Jan AUERNHAMMER Xiaonan ZHANG Ce SHI Lu WANG 《Virtual Reality & Intelligent Hardware》 2023年第2期157-170,共14页
Background With an increasing number of vehicles becoming autonomous,intelligent,and connected,paying attention to the future usage of car human-machine interface with these vehicles should become more relevant.Severa... Background With an increasing number of vehicles becoming autonomous,intelligent,and connected,paying attention to the future usage of car human-machine interface with these vehicles should become more relevant.Several studies have addressed car HMI but were less attentive to designing and implementing interactive glazing for every day(autonomous)driving contexts.Methods Reflecting on the literature,we describe an engineering psychology practice and the design of six novel future user scenarios,which envision the application of a specific set of augmented reality(AR)support user interactions.Additionally,we conduct evaluations on specific scenarios and experiential prototypes,which reveal that these AR scenarios aid the target user groups in experiencing a new type of interaction.The overall evaluation is positive with valuable assessment results and suggestions.Conclusions This study can interest applied psychology educators who aspire to teach how AR can be operationalized in a human-centered design process to students with minimal pre-existing expertise or minimal scientific knowledge in engineering psychology. 展开更多
关键词 Augmented reality interactive glazing Engineering psychology Car human-machine interface Human-computer interaction Human-centered design User experience Generation Z
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Dynamic interactive bitwise meta-holography with ultra-high computational and display frame rates 被引量:2
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作者 Yuncheng Liu Ke Xu +4 位作者 Xuhao Fan Xinger Wang Xuan Yu Wei Xiong Hui Gao 《Opto-Electronic Advances》 SCIE EI CAS CSCD 2024年第1期36-46,共11页
Interactive holography offers unmatched levels of immersion and user engagement in the field of future display.Despite of the substantial progress has been made in dynamic meta-holography,the realization of real-time,... Interactive holography offers unmatched levels of immersion and user engagement in the field of future display.Despite of the substantial progress has been made in dynamic meta-holography,the realization of real-time,highly smooth interactive holography remains a significant challenge due to the computational and display frame rate limitations.In this study,we introduced a dynamic interactive bitwise meta-holography with ultra-high computational and display frame rates.To our knowledge,this is the first reported practical dynamic interactive metasurface holographic system.We spa-tially divided the metasurface device into multiple distinct channels,each projecting a reconstructed sub-pattern.The switching states of these channels were mapped to bitwise operations on a set of bit values,which avoids complex holo-gram computations,enabling an ultra-high computational frame rate.Our approach achieves a computational frame rate of 800 kHz and a display frame rate of 23 kHz on a low-power Raspberry Pi computational platform.According to this methodology,we demonstrated an interactive dynamic holographic Tetris game system that allows interactive gameplay,color display,and on-the-fly hologram creation.Our technology presents an inspiration for advanced dynamic meta-holography,which is promising for a broad range of applications including advanced human-computer interaction,real-time 3D visualization,and next-generation virtual and augmented reality systems. 展开更多
关键词 interactive display meta-holography bitwise operation ultra-high frame rate
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ST-Map:an Interactive Map for Discovering Spatial and Temporal Patterns in Bibliographic Data 被引量:1
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作者 ZUO Chenyu XU Yifan +1 位作者 DING Lingfang MENG Liqiu 《Journal of Geodesy and Geoinformation Science》 CSCD 2024年第1期3-15,共13页
Getting insight into the spatiotemporal distribution patterns of knowledge innovation is receiving increasing attention from policymakers and economic research organizations.Many studies use bibliometric data to analy... Getting insight into the spatiotemporal distribution patterns of knowledge innovation is receiving increasing attention from policymakers and economic research organizations.Many studies use bibliometric data to analyze the popularity of certain research topics,well-adopted methodologies,influential authors,and the interrelationships among research disciplines.However,the visual exploration of the patterns of research topics with an emphasis on their spatial and temporal distribution remains challenging.This study combined a Space-Time Cube(STC)and a 3D glyph to represent the complex multivariate bibliographic data.We further implemented a visual design by developing an interactive interface.The effectiveness,understandability,and engagement of ST-Map are evaluated by seven experts in geovisualization.The results suggest that it is promising to use three-dimensional visualization to show the overview and on-demand details on a single screen. 展开更多
关键词 space-time cube bibliographic data spatiotemporal analysis user study interactive map
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MCIF-Transformer Mask RCNN:Multi-Branch Cross-Scale Interactive Feature Fusion Transformer Model for PET/CT Lung Tumor Instance Segmentation
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作者 Huiling Lu Tao Zhou 《Computers, Materials & Continua》 SCIE EI 2024年第6期4371-4393,共23页
The precise detection and segmentation of tumor lesions are very important for lung cancer computer-aided diagnosis.However,in PET/CT(Positron Emission Tomography/Computed Tomography)lung images,the lesion shapes are ... The precise detection and segmentation of tumor lesions are very important for lung cancer computer-aided diagnosis.However,in PET/CT(Positron Emission Tomography/Computed Tomography)lung images,the lesion shapes are complex,the edges are blurred,and the sample numbers are unbalanced.To solve these problems,this paper proposes a Multi-branch Cross-scale Interactive Feature fusion Transformer model(MCIF-Transformer Mask RCNN)for PET/CT lung tumor instance segmentation,The main innovative works of this paper are as follows:Firstly,the ResNet-Transformer backbone network is used to extract global feature and local feature in lung images.The pixel dependence relationship is established in local and non-local fields to improve the model perception ability.Secondly,the Cross-scale Interactive Feature Enhancement auxiliary network is designed to provide the shallow features to the deep features,and the cross-scale interactive feature enhancement module(CIFEM)is used to enhance the attention ability of the fine-grained features.Thirdly,the Cross-scale Interactive Feature fusion FPN network(CIF-FPN)is constructed to realize bidirectional interactive fusion between deep features and shallow features,and the low-level features are enhanced in deep semantic features.Finally,4 ablation experiments,3 comparison experiments of detection,3 comparison experiments of segmentation and 6 comparison experiments with two-stage and single-stage instance segmentation networks are done on PET/CT lung medical image datasets.The results showed that APdet,APseg,ARdet and ARseg indexes are improved by 5.5%,5.15%,3.11%and 6.79%compared with Mask RCNN(resnet50).Based on the above research,the precise detection and segmentation of the lesion region are realized in this paper.This method has positive significance for the detection of lung tumors. 展开更多
关键词 PET/CT images instance segmentation mask RCNN interactive fusion TRANSFORMER
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Design Method for Optimizing the Interactive Interface of Live Broadcasting Platform for the Elderly Users
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作者 WEI Bi-ze FAN Wei DUAN Ying-ke 《印刷与数字媒体技术研究》 CAS 北大核心 2024年第4期167-178,共12页
In the era of network live broadcasting for everyone,the development of live broadcasting platforms is also more intelligent and diversified.However,in the face of a large group of elderly users,the interface interact... In the era of network live broadcasting for everyone,the development of live broadcasting platforms is also more intelligent and diversified.However,in the face of a large group of elderly users,the interface interaction design mode used is still mainly based on the interaction mode for young groups,and is not designed for elderly users.Therefore,a design method for optimizing the interaction interface of live broadcasting platform for elderly users was proposed in this study.Firstly,the case study method and Delphi expert survey method were used to determine the design needs of elderly users and the design mode was analysed.Secondly,the orthogonal design principle was used to design a test sample of the interactive interface of live broadcasting platform applicable for the elderly users,and then a user evaluation system was established to calculate the weights of the design elements using hierarchical analysis,and then the predictive relationship between the design mode of the interactive interface of live broadcasting platform and the elderly users was established by Quantitative Theory I.Finally,Genetic Algorithm was applied to generate the optimized design scheme.The results showed that the design method based on the Genetic Algorithm and the combination of Quantitative Theory can scientifically and effectively optimize the design of the interactive interface of the live broadcasting platform for the elderly users,and improve the experience of the elderly users. 展开更多
关键词 Live broadcasting platform interaction design Elderly users Genetic Algorithm Quantitative Theory I
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Study on the interactive deformation of bone needles and circum-pelvic soft tissue
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作者 ZHANG Famin LEI Jingtao 《High Technology Letters》 EI CAS 2024年第3期297-303,共7页
During the robot-assisted pelvic fracture reduction,the needle-tissue interactive deformation characteristic is not clear,which affects the accuracy of robotic surgery.In this paper,a layered rig-id-flexible coupling ... During the robot-assisted pelvic fracture reduction,the needle-tissue interactive deformation characteristic is not clear,which affects the accuracy of robotic surgery.In this paper,a layered rig-id-flexible coupling model is proposed,and the needle-tissue interactive deformation under the load-ing is analyzed by the Rayleigh-Ritz method,in accordance with the principle of minimum potential energy.The pelvic musculoskeletal tissue is reversely reconstructed,and the structure of the bone is segmented into cancellous bone and cortical bone.The Mooney-Rivlin five-parameter hyperelastic model is used to simulate muscle,and the Ogden hyperelastic model is used to simulate adipose tis-sue.Finite element simulation is performed by loading different magnitudes of forces.The accuracy of the rigid-flexible coupling model is 0.432 mm,which indicates the correctness of the needle-tis-sue interactive deformation theory analysis. 展开更多
关键词 pelvic fracture reduction rigid-flexible coupling needle-tissue interactive de-formation
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The Application of Formative Assessment in Interactive Comprehensive English Classroom Teaching
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作者 JIN Zhao-hui 《Sino-US English Teaching》 2024年第5期227-231,共5页
Teaching evaluation is an important part of the teaching process of college English courses,and effective formative assessment can reflect the entire teaching process from multiple perspectives and ensure the smooth a... Teaching evaluation is an important part of the teaching process of college English courses,and effective formative assessment can reflect the entire teaching process from multiple perspectives and ensure the smooth achievement of teaching objectives.Formative assessment is an assessment that runs through the entire learning process,based on humanism and constructivism,with various forms of evaluation. 展开更多
关键词 EVALUATION formative assessment interactive Comprehensive English
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基于Interactive Physics的物理习题教学--以2023年高考全国乙卷25题和湖北卷15题为例
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作者 彭鸿宇 王飞 平超 《物理教学探讨》 2024年第3期82-86,共5页
在传统高中物理教学中,多过程碰撞的物理过程很难在板书上展现出来,成为教学的一大难点。基于Interactive Physics仿真功能,以2023年高考全国乙卷25题和湖北卷15题为例,将多过程碰撞的物理过程可视化,直观展现物理模型,帮助学生理解题... 在传统高中物理教学中,多过程碰撞的物理过程很难在板书上展现出来,成为教学的一大难点。基于Interactive Physics仿真功能,以2023年高考全国乙卷25题和湖北卷15题为例,将多过程碰撞的物理过程可视化,直观展现物理模型,帮助学生理解题目的复杂情境,有效缩短学习时间,提高教学质量和教学效率,实现最优化的教学目标。 展开更多
关键词 interactive Physics 可视化 高考物理
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Parameter calibration of the tensile-shear interactive damage constitutive model for sandstone failure
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作者 Yun Shu Zheming Zhu +4 位作者 Meng Wang Weiting Gao Fei Wang Duanying Wan Yuntao Wang 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2024年第4期1153-1174,共22页
The tensile-shear interactive damage(TSID)model is a novel and powerful constitutive model for rock-like materials.This study proposes a methodology to calibrate the TSID model parameters to simulate sandstone.The bas... The tensile-shear interactive damage(TSID)model is a novel and powerful constitutive model for rock-like materials.This study proposes a methodology to calibrate the TSID model parameters to simulate sandstone.The basic parameters of sandstone are determined through a series of static and dynamic tests,including uniaxial compression,Brazilian disc,triaxial compression under varying confining pressures,hydrostatic compression,and dynamic compression and tensile tests with a split Hopkinson pressure bar.Based on the sandstone test results from this study and previous research,a step-by-step procedure for parameter calibration is outlined,which accounts for the categories of the strength surface,equation of state(EOS),strain rate effect,and damage.The calibrated parameters are verified through numerical tests that correspond to the experimental loading conditions.Consistency between numerical results and experimental data indicates the precision and reliability of the calibrated parameters.The methodology presented in this study is scientifically sound,straightforward,and essential for improving the TSID model.Furthermore,it has the potential to contribute to other rock constitutive models,particularly new user-defined models. 展开更多
关键词 Damage constitutive model Parameter calibration Rock modeling SANDSTONE Dynamic impact load Tensile-shear interactive damage(TSID)model
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Research on fault time prediction method for high speed rail BTM unit based on multi method interactive validation
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作者 Limin Fu Junqiang Gou +2 位作者 Chao Sun Hanrui Li Wei Liu 《High-Speed Railway》 2024年第3期164-171,共8页
The Balise Transmission Module(BTM)unit of the on-board train control system is a crucial component.Due to its unique installation position and complex environment,this unit has a higher fault rate within the on-board... The Balise Transmission Module(BTM)unit of the on-board train control system is a crucial component.Due to its unique installation position and complex environment,this unit has a higher fault rate within the on-board train control system.To conduct fault prediction for the BTM unit based on actual fault data,this study proposes a prediction method combining reliability statistics and machine learning,and achieves the fusion of prediction results from different dimensions through multi-method interactive validation.Firstly,a method for predicting equipment fault time targeting batch equipment is introduced.This method utilizes reliability statistics to construct a model of the remaining faultless operating time distribution considering uncertainty,thereby predicting the remaining faultless operating probability of the BTM unit.Secondly,considering the complexity of the BTM unit’s fault mechanism,the small sample size of fault cases,and the potential presence of multiple fault features in fault text records,an individual-oriented fault prediction method based on Bayesian-optimized Gradient Boosting Regression Tree(Bayes-GBRT)is proposed.This method achieves better prediction results compared to linear regression algorithms and random forest regression algorithms,with an average absolute error of only 0.224 years for predicting the fault time of this type of equipment.Finally,a multi-method interactive validation approach is proposed,enabling the fusion and validation of multi-dimensional results.The results indicate that the predicted fault time and the actual fault time conform to a log-normal distribution,and the parameter estimation results are basically consistent,verifying the accuracy and effectiveness of the prediction results.The above research findings can provide technical support for the maintenance and modification of BTM units,effectively reducing maintenance costs and ensuring the safe operation of high-speed railway,thus having practical engineering value for preventive maintenance. 展开更多
关键词 High speed rail BTM unit Remaining faultless operating time Machine learning Multi method interactive verification
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A Double-Interactively Recurrent Fuzzy Cerebellar Model Articulation Controller Model Combined with an Improved Particle Swarm Optimization Method for Fall Detection
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作者 Jyun-Guo Wang 《Computer Systems Science & Engineering》 2024年第5期1149-1170,共22页
In many Eastern and Western countries,falling birth rates have led to the gradual aging of society.Older adults are often left alone at home or live in a long-term care center,which results in them being susceptible t... In many Eastern and Western countries,falling birth rates have led to the gradual aging of society.Older adults are often left alone at home or live in a long-term care center,which results in them being susceptible to unsafe events(such as falls)that can have disastrous consequences.However,automatically detecting falls fromvideo data is challenging,and automatic fall detection methods usually require large volumes of training data,which can be difficult to acquire.To address this problem,video kinematic data can be used as training data,thereby avoiding the requirement of creating a large fall data set.This study integrated an improved particle swarm optimization method into a double interactively recurrent fuzzy cerebellar model articulation controller model to develop a costeffective and accurate fall detection system.First,it obtained an optical flow(OF)trajectory diagram from image sequences by using the OF method,and it solved problems related to focal length and object offset by employing the discrete Fourier transform(DFT)algorithm.Second,this study developed the D-IRFCMAC model,which combines spatial and temporal(recurrent)information.Third,it designed an IPSO(Improved Particle Swarm Optimization)algorithm that effectively strengthens the exploratory capabilities of the proposed D-IRFCMAC(Double-Interactively Recurrent Fuzzy Cerebellar Model Articulation Controller)model in the global search space.The proposed approach outperforms existing state-of-the-art methods in terms of action recognition accuracy on the UR-Fall,UP-Fall,and PRECIS HAR data sets.The UCF11 dataset had an average accuracy of 93.13%,whereas the UCF101 dataset had an average accuracy of 92.19%.The UR-Fall dataset had an accuracy of 100%,the UP-Fall dataset had an accuracy of 99.25%,and the PRECIS HAR dataset had an accuracy of 99.07%. 展开更多
关键词 Double interactively recurrent fuzzy cerebellar model articulation controller(D-IRFCMAC) improved particle swarm optimization(IPSO) fall detection
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Exploration and Practice of“Guiding Interactive”Teaching in Advanced Geochemistry Courses from the Perspective of Constructivist Theory
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作者 Lei Liu Chunming Liu Weijian Zhou 《Journal of Contemporary Educational Research》 2024年第1期52-57,共6页
The construction of geochemical disciplines has brought new vitality to the development of traditional geology.In the new round of“Double First-Class”discipline construction at Central South University,the course of... The construction of geochemical disciplines has brought new vitality to the development of traditional geology.In the new round of“Double First-Class”discipline construction at Central South University,the course of Advanced Geochemistry has effectively stimulated students’interest in learning and further improved their scientific thinking and research innovation skills through the implementation of“Guiding Interactive”teaching reform measures,which has important theoretical significance and practical value. 展开更多
关键词 GEOCHEMISTRY Advanced Geochemistry Teaching reform Guiding interactive
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Research on Visualization and Interactive Design of Plant Configuration Virtual Reality in the Context of Digitalization
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作者 Qiufan Xie 《Journal of Architectural Research and Development》 2024年第3期53-62,共10页
This study aims to explore the application of digital technology in landscape design,focusing on the research of virtual reality visualization and interactive design in the process of plant configuration.Through an in... This study aims to explore the application of digital technology in landscape design,focusing on the research of virtual reality visualization and interactive design in the process of plant configuration.Through an in-depth analysis of digital technology,the study outlines its important role in landscape design,especially in the application of plant configuration.The current application status of virtual reality technology in landscape design is discussed,as well as how interactive design can enhance user experience and participation.Furthermore,the achievements and challenges of digital technology in landscape design are summarized.Finally,it proposes future research directions and suggestions,aiming to provide new ideas and methods for practice and research in the field of landscape design and promote the further application and development of digital technology in landscape design. 展开更多
关键词 lization Plant configuration Virtual reality VISUALIZATION interactive design
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Interactive Media Visual Interpretation of Traditional Chinese Graphics in Urban Public Spaces
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作者 Fu Zhang 《Journal of Electronic Research and Application》 2024年第3期42-46,共5页
This paper focuses on the application of interactive media technology in the visual interpretation of traditional graphic urban public spaces in China.Case studies and practical exploration show that interactive media... This paper focuses on the application of interactive media technology in the visual interpretation of traditional graphic urban public spaces in China.Case studies and practical exploration show that interactive media technologies such as projection mapping,interactive devices,virtual reality technology,etc.,have realized the diversity of traditional graphics display forms in urban public space.The rich interactive experience design enhances the sense of participation and experience of urban citizens and tourists and promotes the visual culture transmission of traditional Chinese graphics.The future urban public space exhibition is destined to continue to deepen the integration of technology and graphics,promote the visual communication of traditional Chinese graphics visual interpretation in urban public space,and promote sustainable innovation in cultural output in urban public space exhibitions around the world. 展开更多
关键词 Motion graphic design Public space interactive media technology
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Research and Application of AI-Based Interactive Exhibits in Wuhan Museum of Science and Technology
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作者 Ting Yan 《Journal of Electronic Research and Application》 2024年第2期95-102,共8页
This article aims to explore the development and application of AI-based interactive exhibits in Wuhan Museum of Science and Technology.By utilizing computer vision,natural language processing,and machine learning tec... This article aims to explore the development and application of AI-based interactive exhibits in Wuhan Museum of Science and Technology.By utilizing computer vision,natural language processing,and machine learning technologies,an innovative exhibit development and application system is proposed.This system employs deep learning algorithms and data analysis methods to achieve real-time perception of visitor behavior and adaptive interaction.The development process involves designing user interfaces and interaction methods to effectively enhance visitor engagement and learning outcomes.Through evaluation and comparison in practical applications,the potential of this system in enhancing exhibit interaction,increasing visitor engagement,improving educational effectiveness,and expanding avenues for scientific knowledge dissemination are validated. 展开更多
关键词 Artificial intelligence interactive exhibits Computer vision Natural language processing Machine learning
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Risk factors and their interactive effects on severe acute pancreatitis complicated with acute gastrointestinal injury 被引量:3
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作者 Jian-Hui Chen Mei-Fen Zhang +1 位作者 Wen-Chao Du Yan-An Zhang 《World Journal of Gastrointestinal Surgery》 SCIE 2023年第8期1712-1718,共7页
BACKGROUND There are many risk factors for severe acute pancreatitis(SAP)complicated with acute gastrointestinal injury(AGI),but few reports on the interaction between these risk factors.AIM To analyze the risk factor... BACKGROUND There are many risk factors for severe acute pancreatitis(SAP)complicated with acute gastrointestinal injury(AGI),but few reports on the interaction between these risk factors.AIM To analyze the risk factors for SAP complicated with AGI and their interactive effects.METHODS We selected 168 SAP patients admitted to our hospital between December 2019 and June 2022.They were divided into AGI group and non-AGI group according to whether AGI was present.Demographic data and laboratory test data were compared between the two groups.The risk factors for SAP with concomitant AGI were analyzed using multifactorial logistic regression,and an analysis of the interaction of the risk factors was performed.RESULTS The percentage of patients with multiple organ dysfunction syndrome,acute physiological and chronic health scoring system II(APACHE II)score,white blood cell count and creatinine(CRE)level was higher in the AGI group than in the non-AGI group.There was a statistically significant difference between the two groups(P<0.05).Logistic regression analysis indicated that an APACHE II score>15 and CRE>100μmol/L were risk factors for SAP complicating AGI.The interaction index of APACHE II score and CRE level was 3.123.CONCLUSION An APACHE II score>15 and CRE level>100μmol/L are independent risk factors for SAP complicated with AGI,and there is a positive interaction between them. 展开更多
关键词 Severe acute pancreatitis Acute gastrointestinal injury Risk factors interactions Acute physiological and chronic health scoring system II CREATININE
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Machine learning with active pharmaceutical ingredient/polymer interaction mechanism:Prediction for complex phase behaviors of pharmaceuticals and formulations 被引量:2
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作者 Kai Ge Yiping Huang Yuanhui Ji 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 2024年第2期263-272,共10页
The high throughput prediction of the thermodynamic phase behavior of active pharmaceutical ingredients(APIs)with pharmaceutically relevant excipients remains a major scientific challenge in the screening of pharmaceu... The high throughput prediction of the thermodynamic phase behavior of active pharmaceutical ingredients(APIs)with pharmaceutically relevant excipients remains a major scientific challenge in the screening of pharmaceutical formulations.In this work,a developed machine-learning model efficiently predicts the solubility of APIs in polymers by learning the phase equilibrium principle and using a few molecular descriptors.Under the few-shot learning framework,thermodynamic theory(perturbed-chain statistical associating fluid theory)was used for data augmentation,and computational chemistry was applied for molecular descriptors'screening.The results showed that the developed machine-learning model can predict the API-polymer phase diagram accurately,broaden the solubility data of APIs in polymers,and reproduce the relationship between API solubility and the interaction mechanisms between API and polymer successfully,which provided efficient guidance for the development of pharmaceutical formulations. 展开更多
关键词 Multi-task machine learning Density functional theory Hydrogen bond interaction MISCIBILITY SOLUBILITY
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