This paper presents a novel working mechanism of a micropump using micropaddles(MPs)to actively manipulate fluid based on 3 D printing technology.The novel working principle is systematically discussed using analysis,...This paper presents a novel working mechanism of a micropump using micropaddles(MPs)to actively manipulate fluid based on 3 D printing technology.The novel working principle is systematically discussed using analysis,computation and experiment methods.A theoretical model is established to research the working mechanism and crucial parameters for driving ability,such as MPs shape,size,vibration amplitude and frequency.Two different 3 D printing techniques that simplify the multi-step process into only one step are introduced to manufacture the prototype pump for investigating the principle experimentally.A testing system is designed to evaluate the flow rate of pumps with eight different vibrating paddles.A maximum flux of 127.9 mL/min is obtained at an applied voltage of 9 V.These experiments show that the active-type mechanical pump could not only freely control flow direction but also change flux by adopting different shapes or distribution ways.The advantage of the novel micropump is the application of the MP structure into the micropump system to actively manipulate fluid with flexibility and high driving ability at fairly low power.展开更多
Fluid manipulation plays an important role in biomedical applications such as biochemical assays,medical diag-nostics,and drug development.Programmable fluidic manipulation at the microscale is highly desired in both ...Fluid manipulation plays an important role in biomedical applications such as biochemical assays,medical diag-nostics,and drug development.Programmable fluidic manipulation at the microscale is highly desired in both fundamental and practical aspects.In this paper,we summarize some of the latest studies that achieve pro-grammable fluidic manipulation through intricate capillaric circuits design,construction of biomimetic metasur-face,and responsive surface wettability control.We highlight the working principle of each system and concisely discuss their design criterion,technical improvements,and implications for future study.We envision that with multidisciplinary efforts,microfluidics would continue to bring vast opportunities to biomedical fields and make contributions to human health.展开更多
基金financial support from the Science and Technology Commission of Shanghai Municipality(STCSM,No.17DZ2291400 and No.17DZ2203100)
文摘This paper presents a novel working mechanism of a micropump using micropaddles(MPs)to actively manipulate fluid based on 3 D printing technology.The novel working principle is systematically discussed using analysis,computation and experiment methods.A theoretical model is established to research the working mechanism and crucial parameters for driving ability,such as MPs shape,size,vibration amplitude and frequency.Two different 3 D printing techniques that simplify the multi-step process into only one step are introduced to manufacture the prototype pump for investigating the principle experimentally.A testing system is designed to evaluate the flow rate of pumps with eight different vibrating paddles.A maximum flux of 127.9 mL/min is obtained at an applied voltage of 9 V.These experiments show that the active-type mechanical pump could not only freely control flow direction but also change flux by adopting different shapes or distribution ways.The advantage of the novel micropump is the application of the MP structure into the micropump system to actively manipulate fluid with flexibility and high driving ability at fairly low power.
基金supported by the National Key Research and Develop-ment Program of China(2020YFB1313100)the National Natural Science Foundation of China(22002018 and 82102511)the Natural Science Foundation of Jiangsu(BK20210021).
文摘Fluid manipulation plays an important role in biomedical applications such as biochemical assays,medical diag-nostics,and drug development.Programmable fluidic manipulation at the microscale is highly desired in both fundamental and practical aspects.In this paper,we summarize some of the latest studies that achieve pro-grammable fluidic manipulation through intricate capillaric circuits design,construction of biomimetic metasur-face,and responsive surface wettability control.We highlight the working principle of each system and concisely discuss their design criterion,technical improvements,and implications for future study.We envision that with multidisciplinary efforts,microfluidics would continue to bring vast opportunities to biomedical fields and make contributions to human health.
