Thalassemia is a group of genetically heterogeneous diseases characterized by hemolytic anemia.To investigate molecular characteristics ofα-andβ-thalassemia among young individuals of marriageable age in Guangdong P...Thalassemia is a group of genetically heterogeneous diseases characterized by hemolytic anemia.To investigate molecular characteristics ofα-andβ-thalassemia among young individuals of marriageable age in Guangdong Province,24,788 subjects with suspected thalassemia were genetically tested forα-andβ-thalassemia by GapPCR and reverse dot blot during 2018–2019.For suspected rare thalassemia cases,DNA sequencing was performed to identify rare and unknown thalassemia gene mutations.A total of 14,346 thalassemia carriers were detected,including 7,556 cases ofα-thalassemia with 25 genotypes and 8α-gene mutations identified,5,860 cases ofβ-thalassemia with 18 genotypes and 18β-gene mutations identified,and 930 cases of compoundα/β-thalassemia.Among them,the frequency of--SEA deletion was the highest inα-thalassemia(66.01%),followed by-α3.7(17.98%)and-α.24(8.22%),and the frequency of CD41-42(-TCTT)mutation was the highest inβ-thalassemia(38.38%),followed by IVS-II-654(C>T)(25.67%),-28(A>G)(15.76%),and CD17(10.01%).In addition,5 rare mutations(--THAI and HKαα,CD113,-90,and CD56)were found in the study population.Our results revealed molecular epidemiological background ofα-andβ-thalassemia in Guangdong Province,which can support optimization of thalassemia prevention and control strategies.We demonstrated that thalassemia is heterogeneous with significant geographical differences and population specificity.展开更多
The couple held hands.They both cherished this marriage very much.They were both in their late thirties,and married for the second time.Their remarried life,however,was about as sweet as their first marriages.They bot...The couple held hands.They both cherished this marriage very much.They were both in their late thirties,and married for the second time.Their remarried life,however,was about as sweet as their first marriages.They both thanked god for giving them the chance to love each other.He had an eight-year-old son,and she had a seven year-old daughter.They treated each other’s child as their own.The couple enjoyed the sunbeam of life and many wonderful things in the world.They lived years being courteous to each other and watching their children grow.They were never seen bickering.Even their children proudly remarked:“Our parents have never gotten mad at each other.”展开更多
In the novel Love in a Fallen City,Bai Liusu and Fan Liuyuan realize the enlightenment of love in the situation of conflicting values and creation.It is an important turning point for the change of their self-consciou...In the novel Love in a Fallen City,Bai Liusu and Fan Liuyuan realize the enlightenment of love in the situation of conflicting values and creation.It is an important turning point for the change of their self-consciousness and social cognition.展开更多
In this article,the epics"The Hundred Thousand and Million-Years-Old Busar-Aldar Khan"and"The Best Man Mimelzekh"from Xinjiang's Mongols are compared in terms of motifs,characters,and events wi...In this article,the epics"The Hundred Thousand and Million-Years-Old Busar-Aldar Khan"and"The Best Man Mimelzekh"from Xinjiang's Mongols are compared in terms of motifs,characters,and events with Kalmyk and Mongolian versions of the chapters on the marriage of Khongor in the"Jangar"epic.The study proposes the following:Firstly,these epics represent an archaic form of the chapter on Khongor's marriage,preserving the motif of"betrothing as yet unborn children",which is considered one of the original elements.Secondly,the chapter on Khongor's marriage in Epic Jangar was originally created as part of the story of Jangar Khan's marriage,reflecting the motif of "betrothing as yet unborn children"at the end of the matriarchal system.Over time,through historical evolution,it transformed into the chapter on Khongor's marriage.展开更多
The rising of aging and the declining of birth rates have forced the public to focus on the youth’s view on marriage.Based on critical discourse analysis and combined with Fairclough’s three-dimensional discourse an...The rising of aging and the declining of birth rates have forced the public to focus on the youth’s view on marriage.Based on critical discourse analysis and combined with Fairclough’s three-dimensional discourse analysis model,this paper builds a“Chinese media News Report Corpus on the topic of‘marriage’”whose news are collected from China Daily.It is found that the discourses are neutral and objective with regard to the advantages and disadvantages of marriage,but in general,it is still a traditional view of marriage that is inevitable and closely related to fertility.Although this is controlled by the policies and the social reasons including declining fertility rate,it deviates from the current view of the youth towards marriage,resulting in many serious consequences such as young people’s rejection.In addition,this research found that male and female have great differences in their views on marriage,and men’s resistance to marriage is far greater than that of women,which is departure from the public’s cognition.The reasons behind this need to be explored in order to solve the marriage and love problems of young people in today’s era and realize the healthy development of young marriage.展开更多
Rural marriage has characteristics such as close relationship with labor production,deep integration of traditional culture,shy and introverted expression of subjective emotions,and illegal and rough marriage.The civi...Rural marriage has characteristics such as close relationship with labor production,deep integration of traditional culture,shy and introverted expression of subjective emotions,and illegal and rough marriage.The civilization evolution of rural marriage forms is moving towards a path that is conducive to the development of production and the pursuit of happiness for farmers,the construction of rural spiritual civilization,and the comprehensive development of rural society.This study analyzes the direction of the evolution of rural marriage form civilization,predicts the trend of rural marriage form civilization evolution,and proposes the future path of rural marriage form civilization evolution,including adhering to human’s most original value expectations of marriage life,drawing nourishment from excellent traditional Chinese culture,and continuously adjusting marriage and family policy tools to keep up with changes in the world of life.展开更多
Background: Vaginal discharge syndrome is a common condition across the world with the main causes being infectious. Rare causes include obstructed hemivagina with ipsilateral renal agenesis (OHVIRA syndrome). Case Pr...Background: Vaginal discharge syndrome is a common condition across the world with the main causes being infectious. Rare causes include obstructed hemivagina with ipsilateral renal agenesis (OHVIRA syndrome). Case Presentation: This case involves an 18-year-old woman with a 9-year history of vaginal discharge treated unsuccessfully by multiple physicians and different health facilities. After she presented to our hospital gynecology clinic with the same complaint she investigated with blood, urine, discharge wet-mount, pelvic ultrasound, and abdominopelvic computed tomography at different times. Preoperatively she was suspected to have OHVIRA syndrome which was successfully surgically treated with a full return of function. Conclusion: This case emphasizes the need to consider non-infectious causes commonly congenital mullerian anomaly in young women presented with long-time vaginal discharge symptoms soon after menarche and which are nonresponding to different multiple medical treatments. In peripheral health institutions like ours, it is best to consider computed tomography if available but better not to forget at least abdominopelvic ultrasound to look for congenital Mullerian anomalies.展开更多
美国加利福尼亚州同性婚姻立法风波自In re Marriage案至2009年5月26日Strauss v.Horton案审结虽已告一段落,但斗争并未结束。这场风波是美国同性婚姻合法化论争的一个缩影。它不仅全面地反映出同性婚姻支持者和反对者的观点,同时也反...美国加利福尼亚州同性婚姻立法风波自In re Marriage案至2009年5月26日Strauss v.Horton案审结虽已告一段落,但斗争并未结束。这场风波是美国同性婚姻合法化论争的一个缩影。它不仅全面地反映出同性婚姻支持者和反对者的观点,同时也反映了同性恋运动的一个斗争策略。他们所争取的至少在很大程度上并不是更多的权利,而是一个"名份",更准确地说是一个同等对待的态度。展开更多
Jane Austen begins Pride and Prejudice with "It is a truth universally acknowledged that, a single man in possession of a good fortune, must be in want of a wife."Hence, there is no doubt that marriage will ...Jane Austen begins Pride and Prejudice with "It is a truth universally acknowledged that, a single man in possession of a good fortune, must be in want of a wife."Hence, there is no doubt that marriage will be a central concern of Pride and Prejudice. In this novel, Austen depicted several types of marriage: Elizabeth and Darcy’s marriage which emphasized equality and independence, Jane and Bingley’s marriage for love’s sake, Charlotte Lucas and Mr. Collins’ practical marriage and the rash marriage between Lydia and Wickham. This thesis is focused on the practical marriage between Charlotte Lucas and Mr. Collins while further explores the reasons behind their pragmatism.展开更多
Doris Lessing is a British writer and novelist. This paper focuses on marriage in Lessing’s To Room Nineteen. In this story, Lessing legitimizes the depression that besets many women who work at home through her narr...Doris Lessing is a British writer and novelist. This paper focuses on marriage in Lessing’s To Room Nineteen. In this story, Lessing legitimizes the depression that besets many women who work at home through her narrative technique and the character of Susan.展开更多
Marriage is a very important part in one's life.But different countries have different wedding ceremonies because of the culture difference.western wedding is simple while Chinese wedding is complex.No matter you ...Marriage is a very important part in one's life.But different countries have different wedding ceremonies because of the culture difference.western wedding is simple while Chinese wedding is complex.No matter you choose the Chinese style or the western style,you should marry the one you love best,and then you can enjoy a beautiful life.展开更多
At the very beginning of the book-Pride and Prejudice,the author said"It is universally acknowledged that a single man in possession of a good fortune must be want of a wife."From this line,we can find that ...At the very beginning of the book-Pride and Prejudice,the author said"It is universally acknowledged that a single man in possession of a good fortune must be want of a wife."From this line,we can find that marriage is the most important thing to women.Sometimes it even equals to men's career at that time.It seems like once a woman married to a rich single man,she succeed in her lifetime"career".The question is what is the standard of that"succeed"? Married to a rich man,or the man you really love,or a man you had a crush on? Everyone keep these questions in mind since very early time,and different people have different opinions.In her short life,Jane Austin,the great novelist,composed six novels and created lot of female characters.Women in her novel had different attitudes toward marriage.Speaking of marriage,Pride and Prejudice must be the most representative work of it,and it is also Jane's masterpiece.Through the different type of marriage of Mr.Bennet's daughters,we can find the Jane's atti tude towards marriage.In this article the author will discuss this issue based on Pride and Prejudice.展开更多
Pride and Prejudice is the masterpiece of Jane Austen.In her novel,through description of four marriages,Jane Austen expressed such views on marriage:marriages based on economics or superficial qualities such as lust,...Pride and Prejudice is the masterpiece of Jane Austen.In her novel,through description of four marriages,Jane Austen expressed such views on marriage:marriages based on economics or superficial qualities such as lust,money,and appearance will inevitably lead to unhappiness,while those based on mutual understanding and true love will be happy and stable.展开更多
Austin’s work-Pride and prejudice, demonstrates three key factors of marriage, namely, a certain economic condition is the guarantee to maintain a happy family, and Love is the foundation of a happy marriage, a ratio...Austin’s work-Pride and prejudice, demonstrates three key factors of marriage, namely, a certain economic condition is the guarantee to maintain a happy family, and Love is the foundation of a happy marriage, a rational and serious attitude towards the matrimonial issue.展开更多
Pride and Prejudice enjoys a worldwide appreciation for its readers. By showing different notions held by people in getting married, the author mainly intends to evoke the moral standards and principles beyond simple ...Pride and Prejudice enjoys a worldwide appreciation for its readers. By showing different notions held by people in getting married, the author mainly intends to evoke the moral standards and principles beyond simple love stories and instruct people's prudence in getting married.展开更多
In the history of English literature,the story of the three sisters,Charlotte(1816~1855),Emily(1818~1848)and Anne(1820~1849),is one of the most important and the saddest pages.They were the daughters of a poor clergym...In the history of English literature,the story of the three sisters,Charlotte(1816~1855),Emily(1818~1848)and Anne(1820~1849),is one of the most important and the saddest pages.They were the daughters of a poor clergyman in the little village of Haworth,Yorkshire,in northern England.Their mother died in 1821.展开更多
1.Is the belief that marriage is between a man and a woman—until recently common even in liberal circles—now presumed so bigoted as to deserve no consideration,even when the exercise of this belief does not actually...1.Is the belief that marriage is between a man and a woman—until recently common even in liberal circles—now presumed so bigoted as to deserve no consideration,even when the exercise of this belief does not actually keep gays from marrying？（Washington News,Feb.24,2014）翻译：婚姻是男女之间的结合,这种观念直到最近就算在思想开明的圈子里都很常见。即便这种观念并不妨碍同性恋者结婚,如今难道也被认为古板而不值得考虑吗？展开更多
This essay aims to discuss and analyse Jane Eyre and Mr. Rochester's attitude towards love and marriage. Struggling for theequality of human dignity crosses through their love from beginning to end. Therefore, we ...This essay aims to discuss and analyse Jane Eyre and Mr. Rochester's attitude towards love and marriage. Struggling for theequality of human dignity crosses through their love from beginning to end. Therefore, we can draw a conclusion--True love and happymarriage are based upon the equality of human dignity between a couple.展开更多
基金the Data quality evaluation study of the national free preconception eugenics health screening program[No.C2018033]。
文摘Thalassemia is a group of genetically heterogeneous diseases characterized by hemolytic anemia.To investigate molecular characteristics ofα-andβ-thalassemia among young individuals of marriageable age in Guangdong Province,24,788 subjects with suspected thalassemia were genetically tested forα-andβ-thalassemia by GapPCR and reverse dot blot during 2018–2019.For suspected rare thalassemia cases,DNA sequencing was performed to identify rare and unknown thalassemia gene mutations.A total of 14,346 thalassemia carriers were detected,including 7,556 cases ofα-thalassemia with 25 genotypes and 8α-gene mutations identified,5,860 cases ofβ-thalassemia with 18 genotypes and 18β-gene mutations identified,and 930 cases of compoundα/β-thalassemia.Among them,the frequency of--SEA deletion was the highest inα-thalassemia(66.01%),followed by-α3.7(17.98%)and-α.24(8.22%),and the frequency of CD41-42(-TCTT)mutation was the highest inβ-thalassemia(38.38%),followed by IVS-II-654(C>T)(25.67%),-28(A>G)(15.76%),and CD17(10.01%).In addition,5 rare mutations(--THAI and HKαα,CD113,-90,and CD56)were found in the study population.Our results revealed molecular epidemiological background ofα-andβ-thalassemia in Guangdong Province,which can support optimization of thalassemia prevention and control strategies.We demonstrated that thalassemia is heterogeneous with significant geographical differences and population specificity.
文摘The couple held hands.They both cherished this marriage very much.They were both in their late thirties,and married for the second time.Their remarried life,however,was about as sweet as their first marriages.They both thanked god for giving them the chance to love each other.He had an eight-year-old son,and she had a seven year-old daughter.They treated each other’s child as their own.The couple enjoyed the sunbeam of life and many wonderful things in the world.They lived years being courteous to each other and watching their children grow.They were never seen bickering.Even their children proudly remarked:“Our parents have never gotten mad at each other.”
文摘In the novel Love in a Fallen City,Bai Liusu and Fan Liuyuan realize the enlightenment of love in the situation of conflicting values and creation.It is an important turning point for the change of their self-consciousness and social cognition.
文摘In this article,the epics"The Hundred Thousand and Million-Years-Old Busar-Aldar Khan"and"The Best Man Mimelzekh"from Xinjiang's Mongols are compared in terms of motifs,characters,and events with Kalmyk and Mongolian versions of the chapters on the marriage of Khongor in the"Jangar"epic.The study proposes the following:Firstly,these epics represent an archaic form of the chapter on Khongor's marriage,preserving the motif of"betrothing as yet unborn children",which is considered one of the original elements.Secondly,the chapter on Khongor's marriage in Epic Jangar was originally created as part of the story of Jangar Khan's marriage,reflecting the motif of "betrothing as yet unborn children"at the end of the matriarchal system.Over time,through historical evolution,it transformed into the chapter on Khongor's marriage.
文摘The rising of aging and the declining of birth rates have forced the public to focus on the youth’s view on marriage.Based on critical discourse analysis and combined with Fairclough’s three-dimensional discourse analysis model,this paper builds a“Chinese media News Report Corpus on the topic of‘marriage’”whose news are collected from China Daily.It is found that the discourses are neutral and objective with regard to the advantages and disadvantages of marriage,but in general,it is still a traditional view of marriage that is inevitable and closely related to fertility.Although this is controlled by the policies and the social reasons including declining fertility rate,it deviates from the current view of the youth towards marriage,resulting in many serious consequences such as young people’s rejection.In addition,this research found that male and female have great differences in their views on marriage,and men’s resistance to marriage is far greater than that of women,which is departure from the public’s cognition.The reasons behind this need to be explored in order to solve the marriage and love problems of young people in today’s era and realize the healthy development of young marriage.
文摘Rural marriage has characteristics such as close relationship with labor production,deep integration of traditional culture,shy and introverted expression of subjective emotions,and illegal and rough marriage.The civilization evolution of rural marriage forms is moving towards a path that is conducive to the development of production and the pursuit of happiness for farmers,the construction of rural spiritual civilization,and the comprehensive development of rural society.This study analyzes the direction of the evolution of rural marriage form civilization,predicts the trend of rural marriage form civilization evolution,and proposes the future path of rural marriage form civilization evolution,including adhering to human’s most original value expectations of marriage life,drawing nourishment from excellent traditional Chinese culture,and continuously adjusting marriage and family policy tools to keep up with changes in the world of life.
文摘Background: Vaginal discharge syndrome is a common condition across the world with the main causes being infectious. Rare causes include obstructed hemivagina with ipsilateral renal agenesis (OHVIRA syndrome). Case Presentation: This case involves an 18-year-old woman with a 9-year history of vaginal discharge treated unsuccessfully by multiple physicians and different health facilities. After she presented to our hospital gynecology clinic with the same complaint she investigated with blood, urine, discharge wet-mount, pelvic ultrasound, and abdominopelvic computed tomography at different times. Preoperatively she was suspected to have OHVIRA syndrome which was successfully surgically treated with a full return of function. Conclusion: This case emphasizes the need to consider non-infectious causes commonly congenital mullerian anomaly in young women presented with long-time vaginal discharge symptoms soon after menarche and which are nonresponding to different multiple medical treatments. In peripheral health institutions like ours, it is best to consider computed tomography if available but better not to forget at least abdominopelvic ultrasound to look for congenital Mullerian anomalies.
文摘美国加利福尼亚州同性婚姻立法风波自In re Marriage案至2009年5月26日Strauss v.Horton案审结虽已告一段落,但斗争并未结束。这场风波是美国同性婚姻合法化论争的一个缩影。它不仅全面地反映出同性婚姻支持者和反对者的观点,同时也反映了同性恋运动的一个斗争策略。他们所争取的至少在很大程度上并不是更多的权利,而是一个"名份",更准确地说是一个同等对待的态度。
文摘Jane Austen begins Pride and Prejudice with "It is a truth universally acknowledged that, a single man in possession of a good fortune, must be in want of a wife."Hence, there is no doubt that marriage will be a central concern of Pride and Prejudice. In this novel, Austen depicted several types of marriage: Elizabeth and Darcy’s marriage which emphasized equality and independence, Jane and Bingley’s marriage for love’s sake, Charlotte Lucas and Mr. Collins’ practical marriage and the rash marriage between Lydia and Wickham. This thesis is focused on the practical marriage between Charlotte Lucas and Mr. Collins while further explores the reasons behind their pragmatism.
文摘Doris Lessing is a British writer and novelist. This paper focuses on marriage in Lessing’s To Room Nineteen. In this story, Lessing legitimizes the depression that besets many women who work at home through her narrative technique and the character of Susan.
文摘Marriage is a very important part in one's life.But different countries have different wedding ceremonies because of the culture difference.western wedding is simple while Chinese wedding is complex.No matter you choose the Chinese style or the western style,you should marry the one you love best,and then you can enjoy a beautiful life.
文摘At the very beginning of the book-Pride and Prejudice,the author said"It is universally acknowledged that a single man in possession of a good fortune must be want of a wife."From this line,we can find that marriage is the most important thing to women.Sometimes it even equals to men's career at that time.It seems like once a woman married to a rich single man,she succeed in her lifetime"career".The question is what is the standard of that"succeed"? Married to a rich man,or the man you really love,or a man you had a crush on? Everyone keep these questions in mind since very early time,and different people have different opinions.In her short life,Jane Austin,the great novelist,composed six novels and created lot of female characters.Women in her novel had different attitudes toward marriage.Speaking of marriage,Pride and Prejudice must be the most representative work of it,and it is also Jane's masterpiece.Through the different type of marriage of Mr.Bennet's daughters,we can find the Jane's atti tude towards marriage.In this article the author will discuss this issue based on Pride and Prejudice.
文摘Pride and Prejudice is the masterpiece of Jane Austen.In her novel,through description of four marriages,Jane Austen expressed such views on marriage:marriages based on economics or superficial qualities such as lust,money,and appearance will inevitably lead to unhappiness,while those based on mutual understanding and true love will be happy and stable.
文摘Austin’s work-Pride and prejudice, demonstrates three key factors of marriage, namely, a certain economic condition is the guarantee to maintain a happy family, and Love is the foundation of a happy marriage, a rational and serious attitude towards the matrimonial issue.
文摘Pride and Prejudice enjoys a worldwide appreciation for its readers. By showing different notions held by people in getting married, the author mainly intends to evoke the moral standards and principles beyond simple love stories and instruct people's prudence in getting married.
文摘In the history of English literature,the story of the three sisters,Charlotte(1816~1855),Emily(1818~1848)and Anne(1820~1849),is one of the most important and the saddest pages.They were the daughters of a poor clergyman in the little village of Haworth,Yorkshire,in northern England.Their mother died in 1821.
文摘1.Is the belief that marriage is between a man and a woman—until recently common even in liberal circles—now presumed so bigoted as to deserve no consideration,even when the exercise of this belief does not actually keep gays from marrying？（Washington News,Feb.24,2014）翻译：婚姻是男女之间的结合,这种观念直到最近就算在思想开明的圈子里都很常见。即便这种观念并不妨碍同性恋者结婚,如今难道也被认为古板而不值得考虑吗？
文摘This essay aims to discuss and analyse Jane Eyre and Mr. Rochester's attitude towards love and marriage. Struggling for theequality of human dignity crosses through their love from beginning to end. Therefore, we can draw a conclusion--True love and happymarriage are based upon the equality of human dignity between a couple.
