AIM: To hypothesize that the product of calculated Model for End-Stage Liver Disease score excluding exception points and donor age(D-MELD) risk capping ± Rule 14 could improve post liver transplant and overall s...AIM: To hypothesize that the product of calculated Model for End-Stage Liver Disease score excluding exception points and donor age(D-MELD) risk capping ± Rule 14 could improve post liver transplant and overall survival after listing.METHODS: Probabilities derived from the United Network for Organ Sharing database between 2002 and 2004 were used to simulate potential outcomes for all patients listed for transplantation. The Markov simula-tion was then modified by screening matches using a 1200 or 1600 D-MELD risk cap ± allowing transplants for Model for End-Stage Liver Disease(MELD) ≤ 14(Rule 14). The differential impact of the rule changes was assessed.RESULTS: The Markov simulation accurately reproduced overall and post transplant survival. A 1200 D-MELD risk cap improved post-transplant survival. Both the 1200 and 1600 risk caps improved overall survival for waitlisted patients. The addition of Rule 14 further improved post transplant and overall survival by redistribution of donor livers to recipients in higher MELD subgroups. The mechanism for improved overall and post-transplant survival after listing was due to shifting a larger percentage of transplants to the moderate MELD score subgroup(MELD 15-29) while also ensuring that high MELD recipients have livers of high quality to achieve excellent post transplant survival.CONCLUSION: A 1200 D-MELD risk cap + Rule 14 provided the greatest overall benefit primarily by focusing liver transplantation towards the moderate MELD recipient.展开更多
A new stereo matching scheme from image pairs based on graph cuts is given,which can solve the problem of large color differences as the result of fusing matching results of graph cuts from different color spaces.This...A new stereo matching scheme from image pairs based on graph cuts is given,which can solve the problem of large color differences as the result of fusing matching results of graph cuts from different color spaces.This scheme builds normalized histogram and reference histogram from matching results,and uses clustering algorithm to process the two histograms.Region histogram statistical method is adopted to retrieve depth data to achieve final matching results.Regular stereo matching library is used to verify this scheme,and experiments reported in this paper support availability of this method for automatic image processing.This scheme renounces the step of manual selection for adaptive color space and can obtain stable matching results.The whole procedure can be executed automatically and improve the integration level of image analysis process.展开更多
文摘AIM: To hypothesize that the product of calculated Model for End-Stage Liver Disease score excluding exception points and donor age(D-MELD) risk capping ± Rule 14 could improve post liver transplant and overall survival after listing.METHODS: Probabilities derived from the United Network for Organ Sharing database between 2002 and 2004 were used to simulate potential outcomes for all patients listed for transplantation. The Markov simula-tion was then modified by screening matches using a 1200 or 1600 D-MELD risk cap ± allowing transplants for Model for End-Stage Liver Disease(MELD) ≤ 14(Rule 14). The differential impact of the rule changes was assessed.RESULTS: The Markov simulation accurately reproduced overall and post transplant survival. A 1200 D-MELD risk cap improved post-transplant survival. Both the 1200 and 1600 risk caps improved overall survival for waitlisted patients. The addition of Rule 14 further improved post transplant and overall survival by redistribution of donor livers to recipients in higher MELD subgroups. The mechanism for improved overall and post-transplant survival after listing was due to shifting a larger percentage of transplants to the moderate MELD score subgroup(MELD 15-29) while also ensuring that high MELD recipients have livers of high quality to achieve excellent post transplant survival.CONCLUSION: A 1200 D-MELD risk cap + Rule 14 provided the greatest overall benefit primarily by focusing liver transplantation towards the moderate MELD recipient.
基金Sponsored by"985"Second Procession Construction of Ministry of Education(3040012040101)
文摘A new stereo matching scheme from image pairs based on graph cuts is given,which can solve the problem of large color differences as the result of fusing matching results of graph cuts from different color spaces.This scheme builds normalized histogram and reference histogram from matching results,and uses clustering algorithm to process the two histograms.Region histogram statistical method is adopted to retrieve depth data to achieve final matching results.Regular stereo matching library is used to verify this scheme,and experiments reported in this paper support availability of this method for automatic image processing.This scheme renounces the step of manual selection for adaptive color space and can obtain stable matching results.The whole procedure can be executed automatically and improve the integration level of image analysis process.