In most organs of mammals, cyclic remodelling of tissues after morphogenesis is minimal; however, reproductive tissues of female animals including endometrium, mammary gland, ovarian follicle and corpus luteum undergo...In most organs of mammals, cyclic remodelling of tissues after morphogenesis is minimal; however, reproductive tissues of female animals including endometrium, mammary gland, ovarian follicle and corpus luteum undergo growth, maturation and involution at various stages in the reproductive cycle or lifespan of the animal. Reconstruction of the extracellular matrix (ECM) is required for the dynamic tissue reorganization characteristic of these tissues. The ECM consists of proteinaceous and nonproteinaceous molecules that provide the tissue-specific, extracellular architecture to which cells attach. Furthermore, interaction of cellular receptors with proteins of the ECM can regulate cellular structure, second messenger generation and gene expression. Mainte-展开更多
Nano-scale phases can enhance or reduce the mechanical properties of materials,so it is very important to control the size of the phases.Copper-rich nanoclusters as matrix defects will significantly reduce the perform...Nano-scale phases can enhance or reduce the mechanical properties of materials,so it is very important to control the size of the phases.Copper-rich nanoclusters as matrix defects will significantly reduce the performance of materials for key nuclear power components,while traditional heat treatment method has a technical bottleneck for the dissolution of nanoclusters.A new method of using the inherent electrical property discrepancies between the matrix material and the nanoclusters to effectively dissolve the nanoclusters through pulsed electric current to realize the recovery of material aging degradation performance is proposed.The performance evolution of simulated steel in the aging-external field repair cycle was studied,and it was found the dislocations as the preferred nucleation sites of nanoclusters were regulated in virtue of the non-thermal effect of current,resulting in a decrease in dislocation density and entanglement release.In the subsequent thermal aging process,the embrittlement rate of the aged and tempered material trained by the electric pulse was slower than that of the untreated sample.When moving dislocations are pinned by nanoclusters under high stress,nano-scale dislocations can be induced into the clusters.The dislocations near the nanoclusters and the newly formed nano-scale dislocations in the nanoclusters act as fast diffusion channels,which can further accelerate the dissolution of the nanoclusters.展开更多
基金This work was supported by the National Natural Science Foundation of China (Grant No. 39970106)the Knowledge Innovation Project of the Chinese Academy of Sciences.
文摘In most organs of mammals, cyclic remodelling of tissues after morphogenesis is minimal; however, reproductive tissues of female animals including endometrium, mammary gland, ovarian follicle and corpus luteum undergo growth, maturation and involution at various stages in the reproductive cycle or lifespan of the animal. Reconstruction of the extracellular matrix (ECM) is required for the dynamic tissue reorganization characteristic of these tissues. The ECM consists of proteinaceous and nonproteinaceous molecules that provide the tissue-specific, extracellular architecture to which cells attach. Furthermore, interaction of cellular receptors with proteins of the ECM can regulate cellular structure, second messenger generation and gene expression. Mainte-
基金financially supported by National Natural Science Foundation of China(Nos.U21B2082,51874023 and U1860206)the National Key Research and Development Program of China(No.2019YFC1908403)+1 种基金the Fundamental Research Funds for the Central Universities(No.FRF-TP-20–04B)the Recruitment Program of Global Experts。
文摘Nano-scale phases can enhance or reduce the mechanical properties of materials,so it is very important to control the size of the phases.Copper-rich nanoclusters as matrix defects will significantly reduce the performance of materials for key nuclear power components,while traditional heat treatment method has a technical bottleneck for the dissolution of nanoclusters.A new method of using the inherent electrical property discrepancies between the matrix material and the nanoclusters to effectively dissolve the nanoclusters through pulsed electric current to realize the recovery of material aging degradation performance is proposed.The performance evolution of simulated steel in the aging-external field repair cycle was studied,and it was found the dislocations as the preferred nucleation sites of nanoclusters were regulated in virtue of the non-thermal effect of current,resulting in a decrease in dislocation density and entanglement release.In the subsequent thermal aging process,the embrittlement rate of the aged and tempered material trained by the electric pulse was slower than that of the untreated sample.When moving dislocations are pinned by nanoclusters under high stress,nano-scale dislocations can be induced into the clusters.The dislocations near the nanoclusters and the newly formed nano-scale dislocations in the nanoclusters act as fast diffusion channels,which can further accelerate the dissolution of the nanoclusters.
