A retrospective study of flow cytometric measurements on paraffin-embedded tumor specimens from 188 patients with bladder tumor was conducted. The results were analyzed in combination with the morphological variation ...A retrospective study of flow cytometric measurements on paraffin-embedded tumor specimens from 188 patients with bladder tumor was conducted. The results were analyzed in combination with the morphological variation of bladder tumors. It was found that the DNA ploid pottern, degree of infiltration and the multiplicity of bladder tumor were closely related with tumor recurrence, among which the DNA ploid pattern was most significant. In aneuploid bladder tumors the recurrent rate and mean annual recurrence frequency were 76.7% and 1.46, and those in the diploid bladder tumors were 18.7% and 0.33 respectively. Aneuploid was the most indicative parameter of the recurrence in bladder tumors. In addition, according to the DNA ploid pattern and DNA index (DI), the aneuploid tumors in our group were divided into 4 types, namely, tetraploid tumors, npn-euploid with DI(?)1.5, non-euploid tumors with DI>1.5 and two-aneuploid tumors. The results showed that the recurrent rate of tetraploid tumors was relatively lower and it became higher and higher in the following order: non-euploid tumors with DI(?)1.5, non-euploid tumors with DI>1.5, and two-aneuploid tumors. This indicates that there are different biological behaviors in tumors with different ploid pattern. Finally, the correlation between DNA ploid pattern and tumor metastasis was also discussed.展开更多
Accurate measurement of flow parameters is important in gas-solid two-phase flow,and such flow has to be dealt with in many processes involving bulk solids handling and transportation.The circular electrostatic sensor...Accurate measurement of flow parameters is important in gas-solid two-phase flow,and such flow has to be dealt with in many processes involving bulk solids handling and transportation.The circular electrostatic sensor is one of those used for gas-solid flow measurement.In this paper,the finite element method(FEM)is used to establish the mathematical model of the sensor,the spatial sensitivity characteristics of the sensors is analyzed,and the analytic model is improved by the nonlinear least square method and the iterative method.Finally,the correlation coefficients between the experimental results and the improved processing are compared and analyzed,and the mathematical expression of the model is improved.The feasibility and practicability of the improved model are verified.展开更多
文摘A retrospective study of flow cytometric measurements on paraffin-embedded tumor specimens from 188 patients with bladder tumor was conducted. The results were analyzed in combination with the morphological variation of bladder tumors. It was found that the DNA ploid pottern, degree of infiltration and the multiplicity of bladder tumor were closely related with tumor recurrence, among which the DNA ploid pattern was most significant. In aneuploid bladder tumors the recurrent rate and mean annual recurrence frequency were 76.7% and 1.46, and those in the diploid bladder tumors were 18.7% and 0.33 respectively. Aneuploid was the most indicative parameter of the recurrence in bladder tumors. In addition, according to the DNA ploid pattern and DNA index (DI), the aneuploid tumors in our group were divided into 4 types, namely, tetraploid tumors, npn-euploid with DI(?)1.5, non-euploid tumors with DI>1.5 and two-aneuploid tumors. The results showed that the recurrent rate of tetraploid tumors was relatively lower and it became higher and higher in the following order: non-euploid tumors with DI(?)1.5, non-euploid tumors with DI>1.5, and two-aneuploid tumors. This indicates that there are different biological behaviors in tumors with different ploid pattern. Finally, the correlation between DNA ploid pattern and tumor metastasis was also discussed.
基金Science and Technology on Electronic Test and Measurement Laboratory(No.9140C12040515X)
文摘Accurate measurement of flow parameters is important in gas-solid two-phase flow,and such flow has to be dealt with in many processes involving bulk solids handling and transportation.The circular electrostatic sensor is one of those used for gas-solid flow measurement.In this paper,the finite element method(FEM)is used to establish the mathematical model of the sensor,the spatial sensitivity characteristics of the sensors is analyzed,and the analytic model is improved by the nonlinear least square method and the iterative method.Finally,the correlation coefficients between the experimental results and the improved processing are compared and analyzed,and the mathematical expression of the model is improved.The feasibility and practicability of the improved model are verified.
