This paper presents a new technique for measuring the bunch length of a high-energy electron beam at a bunch-by-bunch rate in storage rings.This technique uses the time–frequency-domain joint analysis of the bunch si...This paper presents a new technique for measuring the bunch length of a high-energy electron beam at a bunch-by-bunch rate in storage rings.This technique uses the time–frequency-domain joint analysis of the bunch signal to obtain bunch-by-bunch and turn-by-turn longitudinal parameters,such as bunch length and synchronous phase.The bunch signal is obtained using a button electrode with a bandwidth of several gigahertz.The data acquisition device was a high-speed digital oscilloscope with a sampling rate of more than 10 GS/s,and the single-shot sampling data buffer covered thousands of turns.The bunch-length and synchronous phase information were extracted via offline calculations using Python scripts.The calibration coefficient of the system was determined using a commercial streak camera.Moreover,this technique was tested on two different storage rings and successfully captured various longitudinal transient processes during the harmonic cavity debugging process at the Shanghai Synchrotron Radiation Facility(SSRF),and longitudinal instabilities were observed during the single-bunch accumulation process at Hefei Light Source(HLS).For Gaussian-distribution bunches,the uncertainty of the bunch phase obtained using this technique was better than 0.2 ps,and the bunch-length uncertainty was better than 1 ps.The dynamic range exceeded 10 ms.This technology is a powerful and versatile beam diagnostic tool that can be conveniently deployed in high-energy electron storage rings.展开更多
In order to monitor the working state of piston motor and measure its instantaneous rotation speed accurately, the measuring principle and method of instantaneous rotation speed based on industrial personal computer a...In order to monitor the working state of piston motor and measure its instantaneous rotation speed accurately, the measuring principle and method of instantaneous rotation speed based on industrial personal computer and data acquisition card are introduced, and the major error source, influence mechanism and processing method of data quantization error are dis- cussed. By means of hybrid programming approach of LabVIEW and MATLAB, the instantaneous rotation speed measurement system for the piston motor in variable speed hydraulic system is designed. The simulation and experimental results show that the designed instantaneous speed measurement system is feasible. Furthermore, the sampling frequency has an important influ- ence on the instantaneous rotation speed measurement of piston motor and higher sampling frequency can lower quantization er- ror and improve measurement accuracy.展开更多
Earthquake investigations have shown that near-fault pulse-like(NF-P)ground motions have unique characteristics compared to near-fault non-pulse-like(NF-NP)and far-field(FF)ground motions.It is necessary to study the ...Earthquake investigations have shown that near-fault pulse-like(NF-P)ground motions have unique characteristics compared to near-fault non-pulse-like(NF-NP)and far-field(FF)ground motions.It is necessary to study the seismic response of pile-supported wharf(PSW)structures under NF-P ground motions.In this study,a three-dimensional finite element numerical model is created to simulate a PSW.By imparting three types of ground motion,the engineering demand parameters(EDPs)of PSW under NF-P ground motions were analyzed and compared,in which EDPs are the maximum displacement and bending moment of the piles.Twenty intensity measures(IMs)were selected to characterize the properties of ground motions.The correlation between IMs and EDPs was explored.The results show that the piles present larger displacement and bending moment under NF-P ground motions compared to NF-NP and FF ground motions.None of the IMs have a high correlation with EDPs under NF-P ground motions,and these IMs are more applicable to FF ground motions.The correlation coefficients between EDPs and IMs under three types of ground motion were obtained,which will provide a valuable reference for the seismic design of PSWs.展开更多
The resurgence of locally acquired malaria cases in the USA and the persistent global challenge of malaria transmission highlight the urgent need for research to prevent this disease. Despite significant eradication e...The resurgence of locally acquired malaria cases in the USA and the persistent global challenge of malaria transmission highlight the urgent need for research to prevent this disease. Despite significant eradication efforts, malaria remains a serious threat, particularly in regions like Africa. This study explores how integrating Gregor’s Type IV theory with Geographic Information Systems (GIS) improves our understanding of disease dynamics, especially Malaria transmission patterns in Uganda. By combining data-driven algorithms, artificial intelligence, and geospatial analysis, the research aims to determine the most reliable predictors of Malaria incident rates and assess the impact of different factors on transmission. Using diverse predictive modeling techniques including Linear Regression, K-Nearest Neighbor, Neural Network, and Random Forest, the study found that;Random Forest model outperformed the others, demonstrating superior predictive accuracy with an R<sup>2</sup> of approximately 0.88 and a Mean Squared Error (MSE) of 0.0534, Antimalarial treatment was identified as the most influential factor, with mosquito net access associated with a significant reduction in incident rates, while higher temperatures correlated with increased rates. Our study concluded that the Random Forest model was effective in predicting malaria incident rates in Uganda and highlighted the significance of climate factors and preventive measures such as mosquito nets and antimalarial drugs. We recommended that districts with malaria hotspots lacking Indoor Residual Spraying (IRS) coverage prioritize its implementation to mitigate incident rates, while those with high malaria rates in 2020 require immediate attention. By advocating for the use of appropriate predictive models, our research emphasized the importance of evidence-based decision-making in malaria control strategies, aiming to reduce transmission rates and save lives.展开更多
The performance of clay-pile-pier system under earthquake shaking was comprehensively examined via three-dimensional finite element analyses,in which the complex stress-strain relationships of a clay and piled pier sy...The performance of clay-pile-pier system under earthquake shaking was comprehensively examined via three-dimensional finite element analyses,in which the complex stress-strain relationships of a clay and piled pier system were depicted by a hyperbolic-hysteretic and an equivalent elastoplastic model,respectively.One hundred twenty ground motions with varying peak accelerations were considered,along with the variations in bridge superstructure mass and pile flexural rigidity.Comprehensive comparison studies suggested that peak pile-cap acceleration and peak pile-cap velocity are the optimal ground motion intensity measures for seismic responses of the pier and the pile,respectively.Furthermore,based on two optimal ground motion intensity measures and using curvature ductility to quantify different damage states,seismic fragility analyses were performed.The pier generally had no evident damage except when the bridge girder mass was equal to 960 t,which seemed to be comparatively insensitive to the varying pile flexural rigidity.In comparison,the pile was found to be more vulnerable to seismic damage and its failure probabilities tended to clearly reduce with the increment of pile flexural rigidity,while the influence of the bridge girder mass was relatively minor.展开更多
Background:The efficacy of combining immune checkpoint inhibitors(ICIs)with chemotherapy in neoadjuvant therapy for locally advanced gastric cancer has been explored.However,limited research exists on its effectivenes...Background:The efficacy of combining immune checkpoint inhibitors(ICIs)with chemotherapy in neoadjuvant therapy for locally advanced gastric cancer has been explored.However,limited research exists on its effectiveness in conversion therapy,and its superiority over standalone chemotherapy remains to be elucidated.This study aims to investigate the efficacy and survival outcomes of patients treated with ICIs in combination with conversion therapy for locally advanced gastric cancer.Methods:Retrospective data from patients with locally advanced gastric cancer treated with either oxaliplatin+S-1(SOX)alone or in combination with ICIs in conversion therapywere collected.Clinical andpathological characteristics,disease-free survival,andefficacy assessments in nonoperable patients were compared between the 2 treatment groups.Efficacy was further evaluated through dynamic changes in serum markers,and patients’quality of life was assessed using the QLQ-STO22(Gastric Cancer–Specific Quality of Life Questionnaire)quality-of-life measurement scale.Results:A total of 140 patients underwent conversion therapy:80 in the SOX alone group and 60 in the SOX combined with the ICIs group.There were no significant differences in baseline characteristics between the 2 groups.Compared with the SOX alone group,the SOX combined with ICIs group exhibited a higher conversion rate(83.3%vs 75%,P=0.23),R0 resection rate(90.0%vs 83.3%,P=0.31),pathological complete response(pCR)rate(18%vs 5%,P=0.02),median disease-free survival(21.4 vs 16.9 months,P=0.007),the objective response rate in nonoperable patients(60%vs 40%,P=0.301),and median progression-free survival time(7.9 vs 5.7 months,P=0.009).The QLQ-STO22 quality-of-life assessment revealed statistically significant improvements in pain,swallowing difficulties,and dietary restrictions in the combination therapy group compared with those in the monotherapy group.The enhanced efficacy of immune combination with SOX is evident,as demonstrated by the significantly prolonged surgical duration in operated patients(206.6±26.6 min vs 197.8±19.8 min,P=0.35)and intraoperative blood loss(158.9±21.2 mL vs 148.9±25.1 mL,P=0.59).No significant differences were observed in postoperative complications.Conclusions:Compared with the SOX conversion therapy regimen,SOX combined with ICIs demonstrated higher conversion rates,R0 resection rates,pathological response rates,and disease-free survival without increasing surgical difficulty or complications.Nonoperable patients also experienced longer progression-free survival and objective response rates.展开更多
Competency-based assessments for healthcare professionals are critical for safe and effective client outcomes. Rehabilitation clinical skill competency assessments must be validated and revised to produce safe and ski...Competency-based assessments for healthcare professionals are critical for safe and effective client outcomes. Rehabilitation clinical skill competency assessments must be validated and revised to produce safe and skilled practitioners. The revised American Occupational Therapy Association (AOTA) Fieldwork Performance Evaluation (FWPE) instrument measures occupational therapy student performance to determine readiness for practice. The assessment includes thirty-seven competencies that address both profession specific clinical skills and general professional behavior skills. The objective of this study was to use Rasch methods to explore the use of the revised FWPE in actual fieldwork practice and to determine the instrument’s psychometric properties when separating the item components into two distinct subdomains: General Health Professions Competences and Occupational Therapy-Specific Competencies. Internal construct validity and test reliability were analyzed using data from 149 occupational therapy students after completing their initial Level II A fieldwork clinical internship. This study examined the item difficulty hierarchy, item fit, person-fit to model, person separation index, person separation reliability coefficient, strata, ceiling and floor effect, and unidimensionality of the FWPE instrument as a whole and as two separate domains. With the exception of not meeting the criteria for unidimensionality, the full FWPE instrument and the Occupational Therapy-Specific Competencies subdomain showed acceptable item-level psychometrics for reliability and precision. While the General Health Professions Competencies subdomain showed good item-level psychometrics, it was below the criterion for reliability and only separated the sample into two strata. Results support the validity, reliability, and clinical use of the revised FWPE full instrument and the Occupational Therapy-Specific Competencies subdomain to measure entry-level clinical skill competencies in practice.展开更多
The assessment of the measurement error status of online Capacitor Voltage Transformers (CVT) within the power grid is of profound significance to the equitable trade of electric energy and the secure operation of the...The assessment of the measurement error status of online Capacitor Voltage Transformers (CVT) within the power grid is of profound significance to the equitable trade of electric energy and the secure operation of the power grid. This paper advances an online CVT error state evaluation method, anchored in the in-phase relationship and outlier detection. Initially, this method leverages the in-phase relationship to obviate the influence of primary side fluctuations in the grid on assessment accuracy. Subsequently, Principal Component Analysis (PCA) is employed to meticulously disentangle the error change information inherent in the CVT from the measured values and to compute statistics that delineate the error state. Finally, the Local Outlier Factor (LOF) is deployed to discern outliers in the statistics, with thresholds serving to appraise the CVT error state. Experimental results incontrovertibly demonstrate the efficacy of this method, showcasing its prowess in effecting online tracking of CVT error changes and conducting error state assessments. The discernible enhancements in reliability, accuracy, and sensitivity are manifest, with the assessment accuracy reaching an exemplary 0.01%.展开更多
Through long-term production and maintenance practice,various types of stacking steel in the 2250mm hot rolling coiler of Ma Steel were tracked and analyzed,and the causes of stacking steel were summarized.Cor-respond...Through long-term production and maintenance practice,various types of stacking steel in the 2250mm hot rolling coiler of Ma Steel were tracked and analyzed,and the causes of stacking steel were summarized.Cor-responding measures were formulated to effectively reduce the probability of stacking steel.展开更多
Gyrnnarchus niloticus swims by undulations of a long-based dorsal fin, while its body axis is in many cases held straight during swimming. This paper provides a brief relevant introduction to Gyrnnarchus niloticus, wh...Gyrnnarchus niloticus swims by undulations of a long-based dorsal fin, while its body axis is in many cases held straight during swimming. This paper provides a brief relevant introduction to Gyrnnarchus niloticus, which belongs to the African freshwater electric eels but can inspire our bionic interests in propulsion besides its abilities in electric sensing. A special larva of Gyrnnarchus niloticus was morphologically measured by photographing it with a piece of scale-calibrated paper as the background. Then we analyzed the data by a CFD-aided approach. Detailed flow patterns around the larva and a NACA0012 hydrofoil were respectively calculated and visualized at the Reynolds number of 7350 or so. The results show that the profile of Gyrnnarchus niloticus is well streamlined.展开更多
The venturi meter has an advantage in its use,because it can measure flow without being much affected by the type of the measured fluid or flow conditions.Hence,it has excellent versatility and is being widely applied...The venturi meter has an advantage in its use,because it can measure flow without being much affected by the type of the measured fluid or flow conditions.Hence,it has excellent versatility and is being widely applied in many industries.The flow of a liquid containing air is a representative example of a multiphase flow and exhibits complex flow characteristics.In particular,the greater the gas volume fraction(GVF),the more inhomogeneous the flow becomes.As a result,using a venturi meter to measure the rate of a flow that has a high GVF generates an error.In this study,the cause of the error occurred in measuring the flow rate for the multiphase flow when using the venturi meter for analysis by CFD.To ensure the reliability of this study,the accuracy of the multiphase flow models for numerical analysis was verified through comparison between the calculated results of numerical analysis and the experimental data.As a result,the Grace model,which is a multiphase flow model established by an experiment with water and air,was confirmed to have the highest reliability.Finally,the characteristics of the internal flow Held about the multiphase flow analysis result generated by applying the Grace model were analyzed to find the cause of the uncertainty occurring when measuring the flow rate of the multiphase flow using the venturi meter.A phase separation phenomenon occurred due to a density difference of water and air inside the venturi,and flow inhomogeneity happened according to the flow velocity difference of each phase.It was confirmed that this flow inhomogeneity increased as the GVF increased due to the uncertainty of the flow measurement.展开更多
The measurement uncertainty provides complete information about an analytical result. This is very important because several decisions of compliance or non-compliance are based on analytical results in pharmaceutical ...The measurement uncertainty provides complete information about an analytical result. This is very important because several decisions of compliance or non-compliance are based on analytical results in pharmaceutical industries. The aim of this work was to evaluate and discuss the estimation of uncertainty in pharmaceutical analysis. The uncertainty is a useful tool in the assessment of compliance or non-compliance of in-process and final pharmaceutical products as well as in the assessment of pharmaceutical equivalence and stability study of drug products.展开更多
The deformation and residual stress generated by the welding process can seriously affect the use of components.As a result,it is very important to understand the evolution of stress and strain during the welding proc...The deformation and residual stress generated by the welding process can seriously affect the use of components.As a result,it is very important to understand the evolution of stress and strain during the welding process.The strain measurement method based on digital image correlation(DIC)is an excellent method to detect welding strain and residual stress.The out-of-plane translation and out-of-plane rotation introduce errors to the two-dimensional DIC.In this paper,the causes of errors are analyzed theoretically,and the formulas of errors caused by the out-of-plane displacement and the out-of-plane rotation are derived.The out-of-plane translation experiment and the out-of-plane rotation experiment were carried out to verify the theory,and the experimental results are consistent with the theoretical analysis results.The error caused by the out-of-plane translation can be reduced by increasing the object distance;the error caused by the out-of-plane rotation is greatly affected by the rotation angle.展开更多
Workflow logs that record the execution of business processes offer very valuable data resource for real-time enterprise performance measurement. In this paper, a novel scheme that uses the technology of data warehous...Workflow logs that record the execution of business processes offer very valuable data resource for real-time enterprise performance measurement. In this paper, a novel scheme that uses the technology of data warehouse and OLAP to explore workflow logs and create complex analysis reports for enterprise performance measurement is proposed. Three key points of this scheme are studied: 1) the measure set; 2) the open and flexible architecture for workflow logs analysis system; 3) the data models in WFMS and data warehouse. A case study that shows the validity of the scheme is also provided.展开更多
The radiation damage of three individual subcells for GalnP/GaAs//Ge triple-junction solar cells irradiated with electrons and protons is investigated using photoluminescence (PL) measurements. The PL spectra of eac...The radiation damage of three individual subcells for GalnP/GaAs//Ge triple-junction solar cells irradiated with electrons and protons is investigated using photoluminescence (PL) measurements. The PL spectra of each subcell are obtained using different excitation lasers. The PL intensity has a fast degradation after irradiation, and decreases as the displacement damage dose increases. Furthermore, the normalized PL intensity varying with the displacement damage dose is analyzed in detail, and then the lifetime damage coefficients of the recombination centers for GaInP top-cell, GaAs mid-cell and Ge bottom-cell of the triple-junction solar cells are determined from the PL radiative efficiency.展开更多
This paper analyzes current spectrum utilization from all aspects based on related methods of spectrum measurement. The measurement results show that some spectrum resources are not used effectively due to current fix...This paper analyzes current spectrum utilization from all aspects based on related methods of spectrum measurement. The measurement results show that some spectrum resources are not used effectively due to current fixed spectrum allocation policy, and the spectrum occupancy varies dramatically in terms of time and space. These results provide basis for the development of next generation wireless communication technologies such as Cognitive Radio (CR).展开更多
A fully superconducting electron cyclotron resonance (ECR) ion source (SECRAL ID is currently being built in the Institute of Modern Physics, Chinese Academy of Sciences. Its key components are three superconductin...A fully superconducting electron cyclotron resonance (ECR) ion source (SECRAL ID is currently being built in the Institute of Modern Physics, Chinese Academy of Sciences. Its key components are three superconducting solenoids (Nb-Ti/Cu) and six superconducting sextupoles (Nb-Ti/Cu). Different from the conventional supercon- ducting ECR magnetic structure, the SEC17AL Ⅱ includes three superconducting solenoid coils' that are located inside the superconducting sextupoles. The SECRAL Ⅱ can significantly reduce the interaction forces between the sextupole and the solenoids, and the magnets can also be more compact in size. For this multi-component SECRAL Ⅱ generating its self field of -8 T and being often exposed to the high self field, the mechanical analysis has become the main issue to keep their stress at 〈200 MPa on coils. The analytical and experimental results in mechanics are presented in the SECRAL Ⅱ structure. To improve the accuracy and efficiency of analysis, according to the composite rule of micromechanics, the equivalent uniform windings are used to simulate the epoxy-impregnated Nb-Ti/Cu coils. In addition, using low temperature strain gauges and a wireless fast strain acquisition system, a fundamental experiment on the based on our analysis, the stresses and deformations optimized. strains developments of a sextupole is reported. Finally, for its assembly of each SECRAL Ⅱ coil will be further展开更多
The fast and maximum thermal neutron fluxes from the DD-109 neutron generator at the University of Sharjah were experimentally measured by the activation technique using different neutron reactions. The thermal and fa...The fast and maximum thermal neutron fluxes from the DD-109 neutron generator at the University of Sharjah were experimentally measured by the activation technique using different neutron reactions. The thermal and fast neutron fluxes were found to be 2.960 × 10~6 and6.186 × 10~7 n/cm^2 s, respectively. This was done to verify the modeling results for the optimum moderator thickness needed to maximize the thermal neutron flux. The optimum moderator thickness was found to be between 3.5 and4 cm. The present data were compared with the detailed MCNP model-based calculation performed in earlier work to simulate the generator.展开更多
In the current waste gas sampling of fixed source,it is required that deviation of tracking rate of constant velocity sampling should not be more than 10%.When flow rate of the waste gas is less than 5 m/s,the trackin...In the current waste gas sampling of fixed source,it is required that deviation of tracking rate of constant velocity sampling should not be more than 10%.When flow rate of the waste gas is less than 5 m/s,the tracking rate can not meet this requirement.The sampling of fixed velocity can meet the requirement of particulate matter sampling on gas collection volume at low velocity.Through the comparison of two different methods for the determination of particulate matter in waste gas under the low flow velocity of flue gas,it was found that there were some differences between the fixed velocity measurement and the constant velocity measurement.The results showed that measurement result of the fixed velocity was higher than that of constant velocity measurement under low velocity.At the same time,the deviation of fixed velocity measurement was not obvious under different low velocity.展开更多
基金supported by the National Key R&D Program(No.2022YFA1602201)。
文摘This paper presents a new technique for measuring the bunch length of a high-energy electron beam at a bunch-by-bunch rate in storage rings.This technique uses the time–frequency-domain joint analysis of the bunch signal to obtain bunch-by-bunch and turn-by-turn longitudinal parameters,such as bunch length and synchronous phase.The bunch signal is obtained using a button electrode with a bandwidth of several gigahertz.The data acquisition device was a high-speed digital oscilloscope with a sampling rate of more than 10 GS/s,and the single-shot sampling data buffer covered thousands of turns.The bunch-length and synchronous phase information were extracted via offline calculations using Python scripts.The calibration coefficient of the system was determined using a commercial streak camera.Moreover,this technique was tested on two different storage rings and successfully captured various longitudinal transient processes during the harmonic cavity debugging process at the Shanghai Synchrotron Radiation Facility(SSRF),and longitudinal instabilities were observed during the single-bunch accumulation process at Hefei Light Source(HLS).For Gaussian-distribution bunches,the uncertainty of the bunch phase obtained using this technique was better than 0.2 ps,and the bunch-length uncertainty was better than 1 ps.The dynamic range exceeded 10 ms.This technology is a powerful and versatile beam diagnostic tool that can be conveniently deployed in high-energy electron storage rings.
基金National Natural Science Foundation of China(No.51275375,No.51509006)Shaanxi Provincial Natural Science Basic Research Plan(No.2014JQ7246)+1 种基金The Science and Technology of Hubei Province(No.B2015115)Doctoral Research Foundation of Hubei University of Automotive Technology(No.BK201403)
文摘In order to monitor the working state of piston motor and measure its instantaneous rotation speed accurately, the measuring principle and method of instantaneous rotation speed based on industrial personal computer and data acquisition card are introduced, and the major error source, influence mechanism and processing method of data quantization error are dis- cussed. By means of hybrid programming approach of LabVIEW and MATLAB, the instantaneous rotation speed measurement system for the piston motor in variable speed hydraulic system is designed. The simulation and experimental results show that the designed instantaneous speed measurement system is feasible. Furthermore, the sampling frequency has an important influ- ence on the instantaneous rotation speed measurement of piston motor and higher sampling frequency can lower quantization er- ror and improve measurement accuracy.
基金National Natural Science Foundation of China under Grant Nos.42072310 and 51808307。
文摘Earthquake investigations have shown that near-fault pulse-like(NF-P)ground motions have unique characteristics compared to near-fault non-pulse-like(NF-NP)and far-field(FF)ground motions.It is necessary to study the seismic response of pile-supported wharf(PSW)structures under NF-P ground motions.In this study,a three-dimensional finite element numerical model is created to simulate a PSW.By imparting three types of ground motion,the engineering demand parameters(EDPs)of PSW under NF-P ground motions were analyzed and compared,in which EDPs are the maximum displacement and bending moment of the piles.Twenty intensity measures(IMs)were selected to characterize the properties of ground motions.The correlation between IMs and EDPs was explored.The results show that the piles present larger displacement and bending moment under NF-P ground motions compared to NF-NP and FF ground motions.None of the IMs have a high correlation with EDPs under NF-P ground motions,and these IMs are more applicable to FF ground motions.The correlation coefficients between EDPs and IMs under three types of ground motion were obtained,which will provide a valuable reference for the seismic design of PSWs.
文摘The resurgence of locally acquired malaria cases in the USA and the persistent global challenge of malaria transmission highlight the urgent need for research to prevent this disease. Despite significant eradication efforts, malaria remains a serious threat, particularly in regions like Africa. This study explores how integrating Gregor’s Type IV theory with Geographic Information Systems (GIS) improves our understanding of disease dynamics, especially Malaria transmission patterns in Uganda. By combining data-driven algorithms, artificial intelligence, and geospatial analysis, the research aims to determine the most reliable predictors of Malaria incident rates and assess the impact of different factors on transmission. Using diverse predictive modeling techniques including Linear Regression, K-Nearest Neighbor, Neural Network, and Random Forest, the study found that;Random Forest model outperformed the others, demonstrating superior predictive accuracy with an R<sup>2</sup> of approximately 0.88 and a Mean Squared Error (MSE) of 0.0534, Antimalarial treatment was identified as the most influential factor, with mosquito net access associated with a significant reduction in incident rates, while higher temperatures correlated with increased rates. Our study concluded that the Random Forest model was effective in predicting malaria incident rates in Uganda and highlighted the significance of climate factors and preventive measures such as mosquito nets and antimalarial drugs. We recommended that districts with malaria hotspots lacking Indoor Residual Spraying (IRS) coverage prioritize its implementation to mitigate incident rates, while those with high malaria rates in 2020 require immediate attention. By advocating for the use of appropriate predictive models, our research emphasized the importance of evidence-based decision-making in malaria control strategies, aiming to reduce transmission rates and save lives.
基金National Natural Science Foundation of China under Grant Nos.52178353,51808421the Fundamental Research Funds for the Central Universities(WUT:2020III043)。
文摘The performance of clay-pile-pier system under earthquake shaking was comprehensively examined via three-dimensional finite element analyses,in which the complex stress-strain relationships of a clay and piled pier system were depicted by a hyperbolic-hysteretic and an equivalent elastoplastic model,respectively.One hundred twenty ground motions with varying peak accelerations were considered,along with the variations in bridge superstructure mass and pile flexural rigidity.Comprehensive comparison studies suggested that peak pile-cap acceleration and peak pile-cap velocity are the optimal ground motion intensity measures for seismic responses of the pier and the pile,respectively.Furthermore,based on two optimal ground motion intensity measures and using curvature ductility to quantify different damage states,seismic fragility analyses were performed.The pier generally had no evident damage except when the bridge girder mass was equal to 960 t,which seemed to be comparatively insensitive to the varying pile flexural rigidity.In comparison,the pile was found to be more vulnerable to seismic damage and its failure probabilities tended to clearly reduce with the increment of pile flexural rigidity,while the influence of the bridge girder mass was relatively minor.
基金funded by the Science and Technology Plan of Inner Mongolia Autonomous Region(no.2022YFSH0097)the Medical Research Advancement Fund Project(no.TB212014).
文摘Background:The efficacy of combining immune checkpoint inhibitors(ICIs)with chemotherapy in neoadjuvant therapy for locally advanced gastric cancer has been explored.However,limited research exists on its effectiveness in conversion therapy,and its superiority over standalone chemotherapy remains to be elucidated.This study aims to investigate the efficacy and survival outcomes of patients treated with ICIs in combination with conversion therapy for locally advanced gastric cancer.Methods:Retrospective data from patients with locally advanced gastric cancer treated with either oxaliplatin+S-1(SOX)alone or in combination with ICIs in conversion therapywere collected.Clinical andpathological characteristics,disease-free survival,andefficacy assessments in nonoperable patients were compared between the 2 treatment groups.Efficacy was further evaluated through dynamic changes in serum markers,and patients’quality of life was assessed using the QLQ-STO22(Gastric Cancer–Specific Quality of Life Questionnaire)quality-of-life measurement scale.Results:A total of 140 patients underwent conversion therapy:80 in the SOX alone group and 60 in the SOX combined with the ICIs group.There were no significant differences in baseline characteristics between the 2 groups.Compared with the SOX alone group,the SOX combined with ICIs group exhibited a higher conversion rate(83.3%vs 75%,P=0.23),R0 resection rate(90.0%vs 83.3%,P=0.31),pathological complete response(pCR)rate(18%vs 5%,P=0.02),median disease-free survival(21.4 vs 16.9 months,P=0.007),the objective response rate in nonoperable patients(60%vs 40%,P=0.301),and median progression-free survival time(7.9 vs 5.7 months,P=0.009).The QLQ-STO22 quality-of-life assessment revealed statistically significant improvements in pain,swallowing difficulties,and dietary restrictions in the combination therapy group compared with those in the monotherapy group.The enhanced efficacy of immune combination with SOX is evident,as demonstrated by the significantly prolonged surgical duration in operated patients(206.6±26.6 min vs 197.8±19.8 min,P=0.35)and intraoperative blood loss(158.9±21.2 mL vs 148.9±25.1 mL,P=0.59).No significant differences were observed in postoperative complications.Conclusions:Compared with the SOX conversion therapy regimen,SOX combined with ICIs demonstrated higher conversion rates,R0 resection rates,pathological response rates,and disease-free survival without increasing surgical difficulty or complications.Nonoperable patients also experienced longer progression-free survival and objective response rates.
文摘Competency-based assessments for healthcare professionals are critical for safe and effective client outcomes. Rehabilitation clinical skill competency assessments must be validated and revised to produce safe and skilled practitioners. The revised American Occupational Therapy Association (AOTA) Fieldwork Performance Evaluation (FWPE) instrument measures occupational therapy student performance to determine readiness for practice. The assessment includes thirty-seven competencies that address both profession specific clinical skills and general professional behavior skills. The objective of this study was to use Rasch methods to explore the use of the revised FWPE in actual fieldwork practice and to determine the instrument’s psychometric properties when separating the item components into two distinct subdomains: General Health Professions Competences and Occupational Therapy-Specific Competencies. Internal construct validity and test reliability were analyzed using data from 149 occupational therapy students after completing their initial Level II A fieldwork clinical internship. This study examined the item difficulty hierarchy, item fit, person-fit to model, person separation index, person separation reliability coefficient, strata, ceiling and floor effect, and unidimensionality of the FWPE instrument as a whole and as two separate domains. With the exception of not meeting the criteria for unidimensionality, the full FWPE instrument and the Occupational Therapy-Specific Competencies subdomain showed acceptable item-level psychometrics for reliability and precision. While the General Health Professions Competencies subdomain showed good item-level psychometrics, it was below the criterion for reliability and only separated the sample into two strata. Results support the validity, reliability, and clinical use of the revised FWPE full instrument and the Occupational Therapy-Specific Competencies subdomain to measure entry-level clinical skill competencies in practice.
文摘The assessment of the measurement error status of online Capacitor Voltage Transformers (CVT) within the power grid is of profound significance to the equitable trade of electric energy and the secure operation of the power grid. This paper advances an online CVT error state evaluation method, anchored in the in-phase relationship and outlier detection. Initially, this method leverages the in-phase relationship to obviate the influence of primary side fluctuations in the grid on assessment accuracy. Subsequently, Principal Component Analysis (PCA) is employed to meticulously disentangle the error change information inherent in the CVT from the measured values and to compute statistics that delineate the error state. Finally, the Local Outlier Factor (LOF) is deployed to discern outliers in the statistics, with thresholds serving to appraise the CVT error state. Experimental results incontrovertibly demonstrate the efficacy of this method, showcasing its prowess in effecting online tracking of CVT error changes and conducting error state assessments. The discernible enhancements in reliability, accuracy, and sensitivity are manifest, with the assessment accuracy reaching an exemplary 0.01%.
文摘Through long-term production and maintenance practice,various types of stacking steel in the 2250mm hot rolling coiler of Ma Steel were tracked and analyzed,and the causes of stacking steel were summarized.Cor-responding measures were formulated to effectively reduce the probability of stacking steel.
文摘Gyrnnarchus niloticus swims by undulations of a long-based dorsal fin, while its body axis is in many cases held straight during swimming. This paper provides a brief relevant introduction to Gyrnnarchus niloticus, which belongs to the African freshwater electric eels but can inspire our bionic interests in propulsion besides its abilities in electric sensing. A special larva of Gyrnnarchus niloticus was morphologically measured by photographing it with a piece of scale-calibrated paper as the background. Then we analyzed the data by a CFD-aided approach. Detailed flow patterns around the larva and a NACA0012 hydrofoil were respectively calculated and visualized at the Reynolds number of 7350 or so. The results show that the profile of Gyrnnarchus niloticus is well streamlined.
基金supported by the Industrial Infrastructure Program through The Korea Institute for Advancement of Technology(KIAT) Grant funded by the Korea government Ministry of Trade,Industry and Energy(Grant N0000502)
文摘The venturi meter has an advantage in its use,because it can measure flow without being much affected by the type of the measured fluid or flow conditions.Hence,it has excellent versatility and is being widely applied in many industries.The flow of a liquid containing air is a representative example of a multiphase flow and exhibits complex flow characteristics.In particular,the greater the gas volume fraction(GVF),the more inhomogeneous the flow becomes.As a result,using a venturi meter to measure the rate of a flow that has a high GVF generates an error.In this study,the cause of the error occurred in measuring the flow rate for the multiphase flow when using the venturi meter for analysis by CFD.To ensure the reliability of this study,the accuracy of the multiphase flow models for numerical analysis was verified through comparison between the calculated results of numerical analysis and the experimental data.As a result,the Grace model,which is a multiphase flow model established by an experiment with water and air,was confirmed to have the highest reliability.Finally,the characteristics of the internal flow Held about the multiphase flow analysis result generated by applying the Grace model were analyzed to find the cause of the uncertainty occurring when measuring the flow rate of the multiphase flow using the venturi meter.A phase separation phenomenon occurred due to a density difference of water and air inside the venturi,and flow inhomogeneity happened according to the flow velocity difference of each phase.It was confirmed that this flow inhomogeneity increased as the GVF increased due to the uncertainty of the flow measurement.
基金supported by Fundacao de Apoio à Pesquisa do Estado de Sao Paulo(FAPESP)
文摘The measurement uncertainty provides complete information about an analytical result. This is very important because several decisions of compliance or non-compliance are based on analytical results in pharmaceutical industries. The aim of this work was to evaluate and discuss the estimation of uncertainty in pharmaceutical analysis. The uncertainty is a useful tool in the assessment of compliance or non-compliance of in-process and final pharmaceutical products as well as in the assessment of pharmaceutical equivalence and stability study of drug products.
文摘The deformation and residual stress generated by the welding process can seriously affect the use of components.As a result,it is very important to understand the evolution of stress and strain during the welding process.The strain measurement method based on digital image correlation(DIC)is an excellent method to detect welding strain and residual stress.The out-of-plane translation and out-of-plane rotation introduce errors to the two-dimensional DIC.In this paper,the causes of errors are analyzed theoretically,and the formulas of errors caused by the out-of-plane displacement and the out-of-plane rotation are derived.The out-of-plane translation experiment and the out-of-plane rotation experiment were carried out to verify the theory,and the experimental results are consistent with the theoretical analysis results.The error caused by the out-of-plane translation can be reduced by increasing the object distance;the error caused by the out-of-plane rotation is greatly affected by the rotation angle.
文摘Workflow logs that record the execution of business processes offer very valuable data resource for real-time enterprise performance measurement. In this paper, a novel scheme that uses the technology of data warehouse and OLAP to explore workflow logs and create complex analysis reports for enterprise performance measurement is proposed. Three key points of this scheme are studied: 1) the measure set; 2) the open and flexible architecture for workflow logs analysis system; 3) the data models in WFMS and data warehouse. A case study that shows the validity of the scheme is also provided.
基金Supported by the National Natural Science Foundation of China under Grant Nos 10675023,11075018,11375028 and 11675020the Specialized Research Fund for the Doctoral Program of Higher Education under Grant No 20120003110011
文摘The radiation damage of three individual subcells for GalnP/GaAs//Ge triple-junction solar cells irradiated with electrons and protons is investigated using photoluminescence (PL) measurements. The PL spectra of each subcell are obtained using different excitation lasers. The PL intensity has a fast degradation after irradiation, and decreases as the displacement damage dose increases. Furthermore, the normalized PL intensity varying with the displacement damage dose is analyzed in detail, and then the lifetime damage coefficients of the recombination centers for GaInP top-cell, GaAs mid-cell and Ge bottom-cell of the triple-junction solar cells are determined from the PL radiative efficiency.
文摘This paper analyzes current spectrum utilization from all aspects based on related methods of spectrum measurement. The measurement results show that some spectrum resources are not used effectively due to current fixed spectrum allocation policy, and the spectrum occupancy varies dramatically in terms of time and space. These results provide basis for the development of next generation wireless communication technologies such as Cognitive Radio (CR).
基金Supported by the National Natural Science Foundation of China under Grant No 11302225the China Postdoctoral Science Foundation under Grant Nos 2014M560820 and 2015T81071
文摘A fully superconducting electron cyclotron resonance (ECR) ion source (SECRAL ID is currently being built in the Institute of Modern Physics, Chinese Academy of Sciences. Its key components are three superconducting solenoids (Nb-Ti/Cu) and six superconducting sextupoles (Nb-Ti/Cu). Different from the conventional supercon- ducting ECR magnetic structure, the SEC17AL Ⅱ includes three superconducting solenoid coils' that are located inside the superconducting sextupoles. The SECRAL Ⅱ can significantly reduce the interaction forces between the sextupole and the solenoids, and the magnets can also be more compact in size. For this multi-component SECRAL Ⅱ generating its self field of -8 T and being often exposed to the high self field, the mechanical analysis has become the main issue to keep their stress at 〈200 MPa on coils. The analytical and experimental results in mechanics are presented in the SECRAL Ⅱ structure. To improve the accuracy and efficiency of analysis, according to the composite rule of micromechanics, the equivalent uniform windings are used to simulate the epoxy-impregnated Nb-Ti/Cu coils. In addition, using low temperature strain gauges and a wireless fast strain acquisition system, a fundamental experiment on the based on our analysis, the stresses and deformations optimized. strains developments of a sextupole is reported. Finally, for its assembly of each SECRAL Ⅱ coil will be further
文摘The fast and maximum thermal neutron fluxes from the DD-109 neutron generator at the University of Sharjah were experimentally measured by the activation technique using different neutron reactions. The thermal and fast neutron fluxes were found to be 2.960 × 10~6 and6.186 × 10~7 n/cm^2 s, respectively. This was done to verify the modeling results for the optimum moderator thickness needed to maximize the thermal neutron flux. The optimum moderator thickness was found to be between 3.5 and4 cm. The present data were compared with the detailed MCNP model-based calculation performed in earlier work to simulate the generator.
基金Supported by the Shihezi Science and Technology Plan(2018JZ08)the National Natural Science Foundation of China(21667026)
文摘In the current waste gas sampling of fixed source,it is required that deviation of tracking rate of constant velocity sampling should not be more than 10%.When flow rate of the waste gas is less than 5 m/s,the tracking rate can not meet this requirement.The sampling of fixed velocity can meet the requirement of particulate matter sampling on gas collection volume at low velocity.Through the comparison of two different methods for the determination of particulate matter in waste gas under the low flow velocity of flue gas,it was found that there were some differences between the fixed velocity measurement and the constant velocity measurement.The results showed that measurement result of the fixed velocity was higher than that of constant velocity measurement under low velocity.At the same time,the deviation of fixed velocity measurement was not obvious under different low velocity.