This paper presents a new technique for measuring the bunch length of a high-energy electron beam at a bunch-by-bunch rate in storage rings.This technique uses the time–frequency-domain joint analysis of the bunch si...This paper presents a new technique for measuring the bunch length of a high-energy electron beam at a bunch-by-bunch rate in storage rings.This technique uses the time–frequency-domain joint analysis of the bunch signal to obtain bunch-by-bunch and turn-by-turn longitudinal parameters,such as bunch length and synchronous phase.The bunch signal is obtained using a button electrode with a bandwidth of several gigahertz.The data acquisition device was a high-speed digital oscilloscope with a sampling rate of more than 10 GS/s,and the single-shot sampling data buffer covered thousands of turns.The bunch-length and synchronous phase information were extracted via offline calculations using Python scripts.The calibration coefficient of the system was determined using a commercial streak camera.Moreover,this technique was tested on two different storage rings and successfully captured various longitudinal transient processes during the harmonic cavity debugging process at the Shanghai Synchrotron Radiation Facility(SSRF),and longitudinal instabilities were observed during the single-bunch accumulation process at Hefei Light Source(HLS).For Gaussian-distribution bunches,the uncertainty of the bunch phase obtained using this technique was better than 0.2 ps,and the bunch-length uncertainty was better than 1 ps.The dynamic range exceeded 10 ms.This technology is a powerful and versatile beam diagnostic tool that can be conveniently deployed in high-energy electron storage rings.展开更多
A three degree-of-freedom (DOF) planar changeable parallel mechanism is designed by means of control of different drive parameters. This mechanism possesses the characteristics of two kinds of parallel mechanism. Base...A three degree-of-freedom (DOF) planar changeable parallel mechanism is designed by means of control of different drive parameters. This mechanism possesses the characteristics of two kinds of parallel mechanism. Based on its topologic structure, a coordinate system for position analysis is set-up and the forward kinematic solutions are analyzed. It was found that the parallel mechanism is partially decoupled. The relationship between original errors and position-stance error of moving platform is built according to the complete differential-coefficient theory. Then we present a special example with theory values and errors to evaluate the error model, and numerical error solutions are gained. The investigations concentrating on mechanism errors and actuator errors show that the mechanism errors have more influences on the position-stance of the moving platform. It is demonstrated that improving manufacturing and assembly techniques can greatly reduce the moving platform error. The small change in position-stance error in different kinematic positions proves that the error-compensation of software can improve considerably the precision of parallel mechanism.展开更多
This paper introduces a high precision 7m laser measuring instrument developedby the anthors and its operating principle,and systematically analyses the errors havinginfluence on the performance of the measuring instr...This paper introduces a high precision 7m laser measuring instrument developedby the anthors and its operating principle,and systematically analyses the errors havinginfluence on the performance of the measuring instrument.Error analysis and actualverification indicate that all the characteristics reached or exceeded the original designspecifications.展开更多
For fault diagnosis, signal singularity and irregularity discontinuity fraction are very significant characteristics of signal. The discontinuity of output signal represents a system fault . In an angular measuring sy...For fault diagnosis, signal singularity and irregularity discontinuity fraction are very significant characteristics of signal. The discontinuity of output signal represents a system fault . In an angular measuring system, function transformer uses two D/A convertors, output circuit fault of a D/A convertor brings about discontinuity of one phase input voltage amplitude of inductosyn, results in a system error exceeding the allowable error and reduces the system accuracy. This is the reason why discontinuity is detected. Fourier transform has no resolution ability in angular domain, but wavelet can analyse signal in angular and frequency domains. So we decompose the error signal of angular measuring system by wavelet, detect the signal singularity at high frequency layer and find out the accurate position of it.展开更多
Along with the massive applications of the non-linear loads and the impact loads, many non-stationary stochastic signals such as harmonics, inter-harmonics, impulse signals and so on are introduced into the electric n...Along with the massive applications of the non-linear loads and the impact loads, many non-stationary stochastic signals such as harmonics, inter-harmonics, impulse signals and so on are introduced into the electric network, and these non-stationary stochastic signals have had effects on the accuracy of the measurement of electric energy. The traditional method like Fourier Analysis can he applied efficiently on the stationary stochastic signals, hut it has little effect on non-stationary stochastic signals. In light of this, the form of the signals of the electric network in wavelet domain will he discussed in this paper. A measurement method of active power based on multi-resolution analysis in the stochastic process is presented. This method has a wider application scope compared with the traditional method Fourier analysis, and it is of good referential value and practical value in terms of raising the level of the existing electric energy measurement.展开更多
In order to monitor the working state of piston motor and measure its instantaneous rotation speed accurately, the measuring principle and method of instantaneous rotation speed based on industrial personal computer a...In order to monitor the working state of piston motor and measure its instantaneous rotation speed accurately, the measuring principle and method of instantaneous rotation speed based on industrial personal computer and data acquisition card are introduced, and the major error source, influence mechanism and processing method of data quantization error are dis- cussed. By means of hybrid programming approach of LabVIEW and MATLAB, the instantaneous rotation speed measurement system for the piston motor in variable speed hydraulic system is designed. The simulation and experimental results show that the designed instantaneous speed measurement system is feasible. Furthermore, the sampling frequency has an important influ- ence on the instantaneous rotation speed measurement of piston motor and higher sampling frequency can lower quantization er- ror and improve measurement accuracy.展开更多
In a system of systems(SoS),resilience is an important factor in maintaining the functionality,stability,and enhancing the operation effectiveness.From the perspective of resilience,this paper studies the importance o...In a system of systems(SoS),resilience is an important factor in maintaining the functionality,stability,and enhancing the operation effectiveness.From the perspective of resilience,this paper studies the importance of the SoS,and a resilience-based importance measure analysis is conducted to provide suggestions in the design and optimization of the structure of the SoS.In this paper,the components of the SoS are simplified as four kinds of network nodes:sensor,decision point,influencer,and target.In this networked SoS,the number of operation loops is used as the performance indicator,and an approximate algorithm,which is based on eigenvalue of the adjacency matrix,is proposed to calculate the number of operation loops.In order to understand the performance change of the SoS during the attack and defense process in the operations,an integral resilience model is proposed to depict the resilience of the SoS.From different perspectives of enhancing the resilience,different measures,parameters and the corresponding algorithms for the resilience importance of components are proposed.Finally,a case study on an SoS is conducted to verify the validity of the network modelling and the resiliencebased importance analysis method.展开更多
Gyrnnarchus niloticus swims by undulations of a long-based dorsal fin, while its body axis is in many cases held straight during swimming. This paper provides a brief relevant introduction to Gyrnnarchus niloticus, wh...Gyrnnarchus niloticus swims by undulations of a long-based dorsal fin, while its body axis is in many cases held straight during swimming. This paper provides a brief relevant introduction to Gyrnnarchus niloticus, which belongs to the African freshwater electric eels but can inspire our bionic interests in propulsion besides its abilities in electric sensing. A special larva of Gyrnnarchus niloticus was morphologically measured by photographing it with a piece of scale-calibrated paper as the background. Then we analyzed the data by a CFD-aided approach. Detailed flow patterns around the larva and a NACA0012 hydrofoil were respectively calculated and visualized at the Reynolds number of 7350 or so. The results show that the profile of Gyrnnarchus niloticus is well streamlined.展开更多
This paper presents a method for seismic vulnerability analysis of bridge structures based on vector-valued intensity measure (viM), which predicts the limit-state capacities efficiently with multi-intensity measure...This paper presents a method for seismic vulnerability analysis of bridge structures based on vector-valued intensity measure (viM), which predicts the limit-state capacities efficiently with multi-intensity measures of seismic event. Accounting for the uncertainties of the bridge model, ten single-bent overpass bridge structures are taken as samples statistically using Latin hypercube sampling approach. 200 earthquake records are chosen randomly for the uncertainties of ground motions according to the site condition of the bridges. The uncertainties of structural capacity and seismic demand are evaluated with the ratios of demand to capacity in different damage state. By comparing the relative importance of different intensity measures, Sa(T1) and Sa(T2) are chosen as viM. Then, the vector-valued fragility functions of different bridge components are developed. Finally, the system-level vulnerability of the bridge based on viM is studied with Duunett- Sobel class correlation matrix which can consider the correlation effects of different bridge components. The study indicates that an increment IMs from a scalar IM to viM results in a significant reduction in the dispersion of fragility functions and in the uncertainties in evaluating earthquake risk. The feasibility and validity of the proposed vulnerability analysis method is validated and the bridge is more vulnerable than any components.展开更多
The venturi meter has an advantage in its use,because it can measure flow without being much affected by the type of the measured fluid or flow conditions.Hence,it has excellent versatility and is being widely applied...The venturi meter has an advantage in its use,because it can measure flow without being much affected by the type of the measured fluid or flow conditions.Hence,it has excellent versatility and is being widely applied in many industries.The flow of a liquid containing air is a representative example of a multiphase flow and exhibits complex flow characteristics.In particular,the greater the gas volume fraction(GVF),the more inhomogeneous the flow becomes.As a result,using a venturi meter to measure the rate of a flow that has a high GVF generates an error.In this study,the cause of the error occurred in measuring the flow rate for the multiphase flow when using the venturi meter for analysis by CFD.To ensure the reliability of this study,the accuracy of the multiphase flow models for numerical analysis was verified through comparison between the calculated results of numerical analysis and the experimental data.As a result,the Grace model,which is a multiphase flow model established by an experiment with water and air,was confirmed to have the highest reliability.Finally,the characteristics of the internal flow Held about the multiphase flow analysis result generated by applying the Grace model were analyzed to find the cause of the uncertainty occurring when measuring the flow rate of the multiphase flow using the venturi meter.A phase separation phenomenon occurred due to a density difference of water and air inside the venturi,and flow inhomogeneity happened according to the flow velocity difference of each phase.It was confirmed that this flow inhomogeneity increased as the GVF increased due to the uncertainty of the flow measurement.展开更多
The measurement uncertainty provides complete information about an analytical result. This is very important because several decisions of compliance or non-compliance are based on analytical results in pharmaceutical ...The measurement uncertainty provides complete information about an analytical result. This is very important because several decisions of compliance or non-compliance are based on analytical results in pharmaceutical industries. The aim of this work was to evaluate and discuss the estimation of uncertainty in pharmaceutical analysis. The uncertainty is a useful tool in the assessment of compliance or non-compliance of in-process and final pharmaceutical products as well as in the assessment of pharmaceutical equivalence and stability study of drug products.展开更多
Earthquake investigations have shown that near-fault pulse-like(NF-P)ground motions have unique characteristics compared to near-fault non-pulse-like(NF-NP)and far-field(FF)ground motions.It is necessary to study the ...Earthquake investigations have shown that near-fault pulse-like(NF-P)ground motions have unique characteristics compared to near-fault non-pulse-like(NF-NP)and far-field(FF)ground motions.It is necessary to study the seismic response of pile-supported wharf(PSW)structures under NF-P ground motions.In this study,a three-dimensional finite element numerical model is created to simulate a PSW.By imparting three types of ground motion,the engineering demand parameters(EDPs)of PSW under NF-P ground motions were analyzed and compared,in which EDPs are the maximum displacement and bending moment of the piles.Twenty intensity measures(IMs)were selected to characterize the properties of ground motions.The correlation between IMs and EDPs was explored.The results show that the piles present larger displacement and bending moment under NF-P ground motions compared to NF-NP and FF ground motions.None of the IMs have a high correlation with EDPs under NF-P ground motions,and these IMs are more applicable to FF ground motions.The correlation coefficients between EDPs and IMs under three types of ground motion were obtained,which will provide a valuable reference for the seismic design of PSWs.展开更多
The resurgence of locally acquired malaria cases in the USA and the persistent global challenge of malaria transmission highlight the urgent need for research to prevent this disease. Despite significant eradication e...The resurgence of locally acquired malaria cases in the USA and the persistent global challenge of malaria transmission highlight the urgent need for research to prevent this disease. Despite significant eradication efforts, malaria remains a serious threat, particularly in regions like Africa. This study explores how integrating Gregor’s Type IV theory with Geographic Information Systems (GIS) improves our understanding of disease dynamics, especially Malaria transmission patterns in Uganda. By combining data-driven algorithms, artificial intelligence, and geospatial analysis, the research aims to determine the most reliable predictors of Malaria incident rates and assess the impact of different factors on transmission. Using diverse predictive modeling techniques including Linear Regression, K-Nearest Neighbor, Neural Network, and Random Forest, the study found that;Random Forest model outperformed the others, demonstrating superior predictive accuracy with an R<sup>2</sup> of approximately 0.88 and a Mean Squared Error (MSE) of 0.0534, Antimalarial treatment was identified as the most influential factor, with mosquito net access associated with a significant reduction in incident rates, while higher temperatures correlated with increased rates. Our study concluded that the Random Forest model was effective in predicting malaria incident rates in Uganda and highlighted the significance of climate factors and preventive measures such as mosquito nets and antimalarial drugs. We recommended that districts with malaria hotspots lacking Indoor Residual Spraying (IRS) coverage prioritize its implementation to mitigate incident rates, while those with high malaria rates in 2020 require immediate attention. By advocating for the use of appropriate predictive models, our research emphasized the importance of evidence-based decision-making in malaria control strategies, aiming to reduce transmission rates and save lives.展开更多
The performance of clay-pile-pier system under earthquake shaking was comprehensively examined via three-dimensional finite element analyses,in which the complex stress-strain relationships of a clay and piled pier sy...The performance of clay-pile-pier system under earthquake shaking was comprehensively examined via three-dimensional finite element analyses,in which the complex stress-strain relationships of a clay and piled pier system were depicted by a hyperbolic-hysteretic and an equivalent elastoplastic model,respectively.One hundred twenty ground motions with varying peak accelerations were considered,along with the variations in bridge superstructure mass and pile flexural rigidity.Comprehensive comparison studies suggested that peak pile-cap acceleration and peak pile-cap velocity are the optimal ground motion intensity measures for seismic responses of the pier and the pile,respectively.Furthermore,based on two optimal ground motion intensity measures and using curvature ductility to quantify different damage states,seismic fragility analyses were performed.The pier generally had no evident damage except when the bridge girder mass was equal to 960 t,which seemed to be comparatively insensitive to the varying pile flexural rigidity.In comparison,the pile was found to be more vulnerable to seismic damage and its failure probabilities tended to clearly reduce with the increment of pile flexural rigidity,while the influence of the bridge girder mass was relatively minor.展开更多
Affected by many involved factors, different dimensions, data with large difference, incomplete information and so on, the most optimal selection of regional outburst prevention measures for outburst mine has become a...Affected by many involved factors, different dimensions, data with large difference, incomplete information and so on, the most optimal selection of regional outburst prevention measures for outburst mine has become a complicated system project. The traditional way of outburst prevention measure selection belongs to qualitative method, which may cause high-cost of gas control, huge quantities of drilling work, long construction time and even secondary disaster. To solve the above-mentioned problems, in light of occurrence status of coal seam gas in No. 21 mining area of Jinzhushan Tuzhu Mine, through grey fixed weight clustering theory and a combination method of qualitative and quantitative analysis, the judging model with multi-objective classification for optimization of outburst prevention measures was established. The three weight coefficients of outburst prevention technology scheme are sorted, in order to determine the advantages and disadvantages of each outburst prevention technology scheme under the comprehensive evaluation of multi-target. Finally, the problem of quantitative selection for regional outburst prevention technology scheme is solved under the situation of multi-factor mode and incomplete information, which provides reasonable and effective technical measures for prevention of coal and gas outburst disaster.展开更多
The deformation and residual stress generated by the welding process can seriously affect the use of components.As a result,it is very important to understand the evolution of stress and strain during the welding proc...The deformation and residual stress generated by the welding process can seriously affect the use of components.As a result,it is very important to understand the evolution of stress and strain during the welding process.The strain measurement method based on digital image correlation(DIC)is an excellent method to detect welding strain and residual stress.The out-of-plane translation and out-of-plane rotation introduce errors to the two-dimensional DIC.In this paper,the causes of errors are analyzed theoretically,and the formulas of errors caused by the out-of-plane displacement and the out-of-plane rotation are derived.The out-of-plane translation experiment and the out-of-plane rotation experiment were carried out to verify the theory,and the experimental results are consistent with the theoretical analysis results.The error caused by the out-of-plane translation can be reduced by increasing the object distance;the error caused by the out-of-plane rotation is greatly affected by the rotation angle.展开更多
Background:The efficacy of combining immune checkpoint inhibitors(ICIs)with chemotherapy in neoadjuvant therapy for locally advanced gastric cancer has been explored.However,limited research exists on its effectivenes...Background:The efficacy of combining immune checkpoint inhibitors(ICIs)with chemotherapy in neoadjuvant therapy for locally advanced gastric cancer has been explored.However,limited research exists on its effectiveness in conversion therapy,and its superiority over standalone chemotherapy remains to be elucidated.This study aims to investigate the efficacy and survival outcomes of patients treated with ICIs in combination with conversion therapy for locally advanced gastric cancer.Methods:Retrospective data from patients with locally advanced gastric cancer treated with either oxaliplatin+S-1(SOX)alone or in combination with ICIs in conversion therapywere collected.Clinical andpathological characteristics,disease-free survival,andefficacy assessments in nonoperable patients were compared between the 2 treatment groups.Efficacy was further evaluated through dynamic changes in serum markers,and patients’quality of life was assessed using the QLQ-STO22(Gastric Cancer–Specific Quality of Life Questionnaire)quality-of-life measurement scale.Results:A total of 140 patients underwent conversion therapy:80 in the SOX alone group and 60 in the SOX combined with the ICIs group.There were no significant differences in baseline characteristics between the 2 groups.Compared with the SOX alone group,the SOX combined with ICIs group exhibited a higher conversion rate(83.3%vs 75%,P=0.23),R0 resection rate(90.0%vs 83.3%,P=0.31),pathological complete response(pCR)rate(18%vs 5%,P=0.02),median disease-free survival(21.4 vs 16.9 months,P=0.007),the objective response rate in nonoperable patients(60%vs 40%,P=0.301),and median progression-free survival time(7.9 vs 5.7 months,P=0.009).The QLQ-STO22 quality-of-life assessment revealed statistically significant improvements in pain,swallowing difficulties,and dietary restrictions in the combination therapy group compared with those in the monotherapy group.The enhanced efficacy of immune combination with SOX is evident,as demonstrated by the significantly prolonged surgical duration in operated patients(206.6±26.6 min vs 197.8±19.8 min,P=0.35)and intraoperative blood loss(158.9±21.2 mL vs 148.9±25.1 mL,P=0.59).No significant differences were observed in postoperative complications.Conclusions:Compared with the SOX conversion therapy regimen,SOX combined with ICIs demonstrated higher conversion rates,R0 resection rates,pathological response rates,and disease-free survival without increasing surgical difficulty or complications.Nonoperable patients also experienced longer progression-free survival and objective response rates.展开更多
Workflow logs that record the execution of business processes offer very valuable data resource for real-time enterprise performance measurement. In this paper, a novel scheme that uses the technology of data warehous...Workflow logs that record the execution of business processes offer very valuable data resource for real-time enterprise performance measurement. In this paper, a novel scheme that uses the technology of data warehouse and OLAP to explore workflow logs and create complex analysis reports for enterprise performance measurement is proposed. Three key points of this scheme are studied: 1) the measure set; 2) the open and flexible architecture for workflow logs analysis system; 3) the data models in WFMS and data warehouse. A case study that shows the validity of the scheme is also provided.展开更多
The radiation damage of three individual subcells for GalnP/GaAs//Ge triple-junction solar cells irradiated with electrons and protons is investigated using photoluminescence (PL) measurements. The PL spectra of eac...The radiation damage of three individual subcells for GalnP/GaAs//Ge triple-junction solar cells irradiated with electrons and protons is investigated using photoluminescence (PL) measurements. The PL spectra of each subcell are obtained using different excitation lasers. The PL intensity has a fast degradation after irradiation, and decreases as the displacement damage dose increases. Furthermore, the normalized PL intensity varying with the displacement damage dose is analyzed in detail, and then the lifetime damage coefficients of the recombination centers for GaInP top-cell, GaAs mid-cell and Ge bottom-cell of the triple-junction solar cells are determined from the PL radiative efficiency.展开更多
基金supported by the National Key R&D Program(No.2022YFA1602201)。
文摘This paper presents a new technique for measuring the bunch length of a high-energy electron beam at a bunch-by-bunch rate in storage rings.This technique uses the time–frequency-domain joint analysis of the bunch signal to obtain bunch-by-bunch and turn-by-turn longitudinal parameters,such as bunch length and synchronous phase.The bunch signal is obtained using a button electrode with a bandwidth of several gigahertz.The data acquisition device was a high-speed digital oscilloscope with a sampling rate of more than 10 GS/s,and the single-shot sampling data buffer covered thousands of turns.The bunch-length and synchronous phase information were extracted via offline calculations using Python scripts.The calibration coefficient of the system was determined using a commercial streak camera.Moreover,this technique was tested on two different storage rings and successfully captured various longitudinal transient processes during the harmonic cavity debugging process at the Shanghai Synchrotron Radiation Facility(SSRF),and longitudinal instabilities were observed during the single-bunch accumulation process at Hefei Light Source(HLS).For Gaussian-distribution bunches,the uncertainty of the bunch phase obtained using this technique was better than 0.2 ps,and the bunch-length uncertainty was better than 1 ps.The dynamic range exceeded 10 ms.This technology is a powerful and versatile beam diagnostic tool that can be conveniently deployed in high-energy electron storage rings.
基金Preject 50225519 supported by the National Outstanding Youth Science Foundation of China
文摘A three degree-of-freedom (DOF) planar changeable parallel mechanism is designed by means of control of different drive parameters. This mechanism possesses the characteristics of two kinds of parallel mechanism. Based on its topologic structure, a coordinate system for position analysis is set-up and the forward kinematic solutions are analyzed. It was found that the parallel mechanism is partially decoupled. The relationship between original errors and position-stance error of moving platform is built according to the complete differential-coefficient theory. Then we present a special example with theory values and errors to evaluate the error model, and numerical error solutions are gained. The investigations concentrating on mechanism errors and actuator errors show that the mechanism errors have more influences on the position-stance of the moving platform. It is demonstrated that improving manufacturing and assembly techniques can greatly reduce the moving platform error. The small change in position-stance error in different kinematic positions proves that the error-compensation of software can improve considerably the precision of parallel mechanism.
文摘This paper introduces a high precision 7m laser measuring instrument developedby the anthors and its operating principle,and systematically analyses the errors havinginfluence on the performance of the measuring instrument.Error analysis and actualverification indicate that all the characteristics reached or exceeded the original designspecifications.
文摘For fault diagnosis, signal singularity and irregularity discontinuity fraction are very significant characteristics of signal. The discontinuity of output signal represents a system fault . In an angular measuring system, function transformer uses two D/A convertors, output circuit fault of a D/A convertor brings about discontinuity of one phase input voltage amplitude of inductosyn, results in a system error exceeding the allowable error and reduces the system accuracy. This is the reason why discontinuity is detected. Fourier transform has no resolution ability in angular domain, but wavelet can analyse signal in angular and frequency domains. So we decompose the error signal of angular measuring system by wavelet, detect the signal singularity at high frequency layer and find out the accurate position of it.
文摘Along with the massive applications of the non-linear loads and the impact loads, many non-stationary stochastic signals such as harmonics, inter-harmonics, impulse signals and so on are introduced into the electric network, and these non-stationary stochastic signals have had effects on the accuracy of the measurement of electric energy. The traditional method like Fourier Analysis can he applied efficiently on the stationary stochastic signals, hut it has little effect on non-stationary stochastic signals. In light of this, the form of the signals of the electric network in wavelet domain will he discussed in this paper. A measurement method of active power based on multi-resolution analysis in the stochastic process is presented. This method has a wider application scope compared with the traditional method Fourier analysis, and it is of good referential value and practical value in terms of raising the level of the existing electric energy measurement.
基金National Natural Science Foundation of China(No.51275375,No.51509006)Shaanxi Provincial Natural Science Basic Research Plan(No.2014JQ7246)+1 种基金The Science and Technology of Hubei Province(No.B2015115)Doctoral Research Foundation of Hubei University of Automotive Technology(No.BK201403)
文摘In order to monitor the working state of piston motor and measure its instantaneous rotation speed accurately, the measuring principle and method of instantaneous rotation speed based on industrial personal computer and data acquisition card are introduced, and the major error source, influence mechanism and processing method of data quantization error are dis- cussed. By means of hybrid programming approach of LabVIEW and MATLAB, the instantaneous rotation speed measurement system for the piston motor in variable speed hydraulic system is designed. The simulation and experimental results show that the designed instantaneous speed measurement system is feasible. Furthermore, the sampling frequency has an important influ- ence on the instantaneous rotation speed measurement of piston motor and higher sampling frequency can lower quantization er- ror and improve measurement accuracy.
基金supported by the National Natural Science Foundation of China(71571004)
文摘In a system of systems(SoS),resilience is an important factor in maintaining the functionality,stability,and enhancing the operation effectiveness.From the perspective of resilience,this paper studies the importance of the SoS,and a resilience-based importance measure analysis is conducted to provide suggestions in the design and optimization of the structure of the SoS.In this paper,the components of the SoS are simplified as four kinds of network nodes:sensor,decision point,influencer,and target.In this networked SoS,the number of operation loops is used as the performance indicator,and an approximate algorithm,which is based on eigenvalue of the adjacency matrix,is proposed to calculate the number of operation loops.In order to understand the performance change of the SoS during the attack and defense process in the operations,an integral resilience model is proposed to depict the resilience of the SoS.From different perspectives of enhancing the resilience,different measures,parameters and the corresponding algorithms for the resilience importance of components are proposed.Finally,a case study on an SoS is conducted to verify the validity of the network modelling and the resiliencebased importance analysis method.
文摘Gyrnnarchus niloticus swims by undulations of a long-based dorsal fin, while its body axis is in many cases held straight during swimming. This paper provides a brief relevant introduction to Gyrnnarchus niloticus, which belongs to the African freshwater electric eels but can inspire our bionic interests in propulsion besides its abilities in electric sensing. A special larva of Gyrnnarchus niloticus was morphologically measured by photographing it with a piece of scale-calibrated paper as the background. Then we analyzed the data by a CFD-aided approach. Detailed flow patterns around the larva and a NACA0012 hydrofoil were respectively calculated and visualized at the Reynolds number of 7350 or so. The results show that the profile of Gyrnnarchus niloticus is well streamlined.
基金National Program on Key Basic Research Project of China(973)under Grant No.2011CB013603National Natural Science Foundation of China under Grant Nos.51378341,91315301Tianjin Municipal Natural Science Foundation under Grant No.13JCQNJC07200
文摘This paper presents a method for seismic vulnerability analysis of bridge structures based on vector-valued intensity measure (viM), which predicts the limit-state capacities efficiently with multi-intensity measures of seismic event. Accounting for the uncertainties of the bridge model, ten single-bent overpass bridge structures are taken as samples statistically using Latin hypercube sampling approach. 200 earthquake records are chosen randomly for the uncertainties of ground motions according to the site condition of the bridges. The uncertainties of structural capacity and seismic demand are evaluated with the ratios of demand to capacity in different damage state. By comparing the relative importance of different intensity measures, Sa(T1) and Sa(T2) are chosen as viM. Then, the vector-valued fragility functions of different bridge components are developed. Finally, the system-level vulnerability of the bridge based on viM is studied with Duunett- Sobel class correlation matrix which can consider the correlation effects of different bridge components. The study indicates that an increment IMs from a scalar IM to viM results in a significant reduction in the dispersion of fragility functions and in the uncertainties in evaluating earthquake risk. The feasibility and validity of the proposed vulnerability analysis method is validated and the bridge is more vulnerable than any components.
基金supported by the Industrial Infrastructure Program through The Korea Institute for Advancement of Technology(KIAT) Grant funded by the Korea government Ministry of Trade,Industry and Energy(Grant N0000502)
文摘The venturi meter has an advantage in its use,because it can measure flow without being much affected by the type of the measured fluid or flow conditions.Hence,it has excellent versatility and is being widely applied in many industries.The flow of a liquid containing air is a representative example of a multiphase flow and exhibits complex flow characteristics.In particular,the greater the gas volume fraction(GVF),the more inhomogeneous the flow becomes.As a result,using a venturi meter to measure the rate of a flow that has a high GVF generates an error.In this study,the cause of the error occurred in measuring the flow rate for the multiphase flow when using the venturi meter for analysis by CFD.To ensure the reliability of this study,the accuracy of the multiphase flow models for numerical analysis was verified through comparison between the calculated results of numerical analysis and the experimental data.As a result,the Grace model,which is a multiphase flow model established by an experiment with water and air,was confirmed to have the highest reliability.Finally,the characteristics of the internal flow Held about the multiphase flow analysis result generated by applying the Grace model were analyzed to find the cause of the uncertainty occurring when measuring the flow rate of the multiphase flow using the venturi meter.A phase separation phenomenon occurred due to a density difference of water and air inside the venturi,and flow inhomogeneity happened according to the flow velocity difference of each phase.It was confirmed that this flow inhomogeneity increased as the GVF increased due to the uncertainty of the flow measurement.
基金supported by Fundacao de Apoio à Pesquisa do Estado de Sao Paulo(FAPESP)
文摘The measurement uncertainty provides complete information about an analytical result. This is very important because several decisions of compliance or non-compliance are based on analytical results in pharmaceutical industries. The aim of this work was to evaluate and discuss the estimation of uncertainty in pharmaceutical analysis. The uncertainty is a useful tool in the assessment of compliance or non-compliance of in-process and final pharmaceutical products as well as in the assessment of pharmaceutical equivalence and stability study of drug products.
基金National Natural Science Foundation of China under Grant Nos.42072310 and 51808307。
文摘Earthquake investigations have shown that near-fault pulse-like(NF-P)ground motions have unique characteristics compared to near-fault non-pulse-like(NF-NP)and far-field(FF)ground motions.It is necessary to study the seismic response of pile-supported wharf(PSW)structures under NF-P ground motions.In this study,a three-dimensional finite element numerical model is created to simulate a PSW.By imparting three types of ground motion,the engineering demand parameters(EDPs)of PSW under NF-P ground motions were analyzed and compared,in which EDPs are the maximum displacement and bending moment of the piles.Twenty intensity measures(IMs)were selected to characterize the properties of ground motions.The correlation between IMs and EDPs was explored.The results show that the piles present larger displacement and bending moment under NF-P ground motions compared to NF-NP and FF ground motions.None of the IMs have a high correlation with EDPs under NF-P ground motions,and these IMs are more applicable to FF ground motions.The correlation coefficients between EDPs and IMs under three types of ground motion were obtained,which will provide a valuable reference for the seismic design of PSWs.
文摘The resurgence of locally acquired malaria cases in the USA and the persistent global challenge of malaria transmission highlight the urgent need for research to prevent this disease. Despite significant eradication efforts, malaria remains a serious threat, particularly in regions like Africa. This study explores how integrating Gregor’s Type IV theory with Geographic Information Systems (GIS) improves our understanding of disease dynamics, especially Malaria transmission patterns in Uganda. By combining data-driven algorithms, artificial intelligence, and geospatial analysis, the research aims to determine the most reliable predictors of Malaria incident rates and assess the impact of different factors on transmission. Using diverse predictive modeling techniques including Linear Regression, K-Nearest Neighbor, Neural Network, and Random Forest, the study found that;Random Forest model outperformed the others, demonstrating superior predictive accuracy with an R<sup>2</sup> of approximately 0.88 and a Mean Squared Error (MSE) of 0.0534, Antimalarial treatment was identified as the most influential factor, with mosquito net access associated with a significant reduction in incident rates, while higher temperatures correlated with increased rates. Our study concluded that the Random Forest model was effective in predicting malaria incident rates in Uganda and highlighted the significance of climate factors and preventive measures such as mosquito nets and antimalarial drugs. We recommended that districts with malaria hotspots lacking Indoor Residual Spraying (IRS) coverage prioritize its implementation to mitigate incident rates, while those with high malaria rates in 2020 require immediate attention. By advocating for the use of appropriate predictive models, our research emphasized the importance of evidence-based decision-making in malaria control strategies, aiming to reduce transmission rates and save lives.
基金National Natural Science Foundation of China under Grant Nos.52178353,51808421the Fundamental Research Funds for the Central Universities(WUT:2020III043)。
文摘The performance of clay-pile-pier system under earthquake shaking was comprehensively examined via three-dimensional finite element analyses,in which the complex stress-strain relationships of a clay and piled pier system were depicted by a hyperbolic-hysteretic and an equivalent elastoplastic model,respectively.One hundred twenty ground motions with varying peak accelerations were considered,along with the variations in bridge superstructure mass and pile flexural rigidity.Comprehensive comparison studies suggested that peak pile-cap acceleration and peak pile-cap velocity are the optimal ground motion intensity measures for seismic responses of the pier and the pile,respectively.Furthermore,based on two optimal ground motion intensity measures and using curvature ductility to quantify different damage states,seismic fragility analyses were performed.The pier generally had no evident damage except when the bridge girder mass was equal to 960 t,which seemed to be comparatively insensitive to the varying pile flexural rigidity.In comparison,the pile was found to be more vulnerable to seismic damage and its failure probabilities tended to clearly reduce with the increment of pile flexural rigidity,while the influence of the bridge girder mass was relatively minor.
文摘Affected by many involved factors, different dimensions, data with large difference, incomplete information and so on, the most optimal selection of regional outburst prevention measures for outburst mine has become a complicated system project. The traditional way of outburst prevention measure selection belongs to qualitative method, which may cause high-cost of gas control, huge quantities of drilling work, long construction time and even secondary disaster. To solve the above-mentioned problems, in light of occurrence status of coal seam gas in No. 21 mining area of Jinzhushan Tuzhu Mine, through grey fixed weight clustering theory and a combination method of qualitative and quantitative analysis, the judging model with multi-objective classification for optimization of outburst prevention measures was established. The three weight coefficients of outburst prevention technology scheme are sorted, in order to determine the advantages and disadvantages of each outburst prevention technology scheme under the comprehensive evaluation of multi-target. Finally, the problem of quantitative selection for regional outburst prevention technology scheme is solved under the situation of multi-factor mode and incomplete information, which provides reasonable and effective technical measures for prevention of coal and gas outburst disaster.
文摘The deformation and residual stress generated by the welding process can seriously affect the use of components.As a result,it is very important to understand the evolution of stress and strain during the welding process.The strain measurement method based on digital image correlation(DIC)is an excellent method to detect welding strain and residual stress.The out-of-plane translation and out-of-plane rotation introduce errors to the two-dimensional DIC.In this paper,the causes of errors are analyzed theoretically,and the formulas of errors caused by the out-of-plane displacement and the out-of-plane rotation are derived.The out-of-plane translation experiment and the out-of-plane rotation experiment were carried out to verify the theory,and the experimental results are consistent with the theoretical analysis results.The error caused by the out-of-plane translation can be reduced by increasing the object distance;the error caused by the out-of-plane rotation is greatly affected by the rotation angle.
基金funded by the Science and Technology Plan of Inner Mongolia Autonomous Region(no.2022YFSH0097)the Medical Research Advancement Fund Project(no.TB212014).
文摘Background:The efficacy of combining immune checkpoint inhibitors(ICIs)with chemotherapy in neoadjuvant therapy for locally advanced gastric cancer has been explored.However,limited research exists on its effectiveness in conversion therapy,and its superiority over standalone chemotherapy remains to be elucidated.This study aims to investigate the efficacy and survival outcomes of patients treated with ICIs in combination with conversion therapy for locally advanced gastric cancer.Methods:Retrospective data from patients with locally advanced gastric cancer treated with either oxaliplatin+S-1(SOX)alone or in combination with ICIs in conversion therapywere collected.Clinical andpathological characteristics,disease-free survival,andefficacy assessments in nonoperable patients were compared between the 2 treatment groups.Efficacy was further evaluated through dynamic changes in serum markers,and patients’quality of life was assessed using the QLQ-STO22(Gastric Cancer–Specific Quality of Life Questionnaire)quality-of-life measurement scale.Results:A total of 140 patients underwent conversion therapy:80 in the SOX alone group and 60 in the SOX combined with the ICIs group.There were no significant differences in baseline characteristics between the 2 groups.Compared with the SOX alone group,the SOX combined with ICIs group exhibited a higher conversion rate(83.3%vs 75%,P=0.23),R0 resection rate(90.0%vs 83.3%,P=0.31),pathological complete response(pCR)rate(18%vs 5%,P=0.02),median disease-free survival(21.4 vs 16.9 months,P=0.007),the objective response rate in nonoperable patients(60%vs 40%,P=0.301),and median progression-free survival time(7.9 vs 5.7 months,P=0.009).The QLQ-STO22 quality-of-life assessment revealed statistically significant improvements in pain,swallowing difficulties,and dietary restrictions in the combination therapy group compared with those in the monotherapy group.The enhanced efficacy of immune combination with SOX is evident,as demonstrated by the significantly prolonged surgical duration in operated patients(206.6±26.6 min vs 197.8±19.8 min,P=0.35)and intraoperative blood loss(158.9±21.2 mL vs 148.9±25.1 mL,P=0.59).No significant differences were observed in postoperative complications.Conclusions:Compared with the SOX conversion therapy regimen,SOX combined with ICIs demonstrated higher conversion rates,R0 resection rates,pathological response rates,and disease-free survival without increasing surgical difficulty or complications.Nonoperable patients also experienced longer progression-free survival and objective response rates.
文摘Workflow logs that record the execution of business processes offer very valuable data resource for real-time enterprise performance measurement. In this paper, a novel scheme that uses the technology of data warehouse and OLAP to explore workflow logs and create complex analysis reports for enterprise performance measurement is proposed. Three key points of this scheme are studied: 1) the measure set; 2) the open and flexible architecture for workflow logs analysis system; 3) the data models in WFMS and data warehouse. A case study that shows the validity of the scheme is also provided.
基金Supported by the National Natural Science Foundation of China under Grant Nos 10675023,11075018,11375028 and 11675020the Specialized Research Fund for the Doctoral Program of Higher Education under Grant No 20120003110011
文摘The radiation damage of three individual subcells for GalnP/GaAs//Ge triple-junction solar cells irradiated with electrons and protons is investigated using photoluminescence (PL) measurements. The PL spectra of each subcell are obtained using different excitation lasers. The PL intensity has a fast degradation after irradiation, and decreases as the displacement damage dose increases. Furthermore, the normalized PL intensity varying with the displacement damage dose is analyzed in detail, and then the lifetime damage coefficients of the recombination centers for GaInP top-cell, GaAs mid-cell and Ge bottom-cell of the triple-junction solar cells are determined from the PL radiative efficiency.