Mechanotransduction is essential for cell fate and behavior,and F-actin plays a key role in the generation and transmission of molecular forces.A recent study published in Nature Communication presented a novel highpr...Mechanotransduction is essential for cell fate and behavior,and F-actin plays a key role in the generation and transmission of molecular forces.A recent study published in Nature Communication presented a novel highprecision molecular tension measurement method using a Forster resonance energy transfer-based tension sensor with separated load-bearing function within distinct F-actin structures,and demonstrated that cellular mechanical anisotropy depends on cell shape,loading direction,and magnitude.展开更多
基金supported by National Natural Science Foundation of China(32201070).
文摘Mechanotransduction is essential for cell fate and behavior,and F-actin plays a key role in the generation and transmission of molecular forces.A recent study published in Nature Communication presented a novel highprecision molecular tension measurement method using a Forster resonance energy transfer-based tension sensor with separated load-bearing function within distinct F-actin structures,and demonstrated that cellular mechanical anisotropy depends on cell shape,loading direction,and magnitude.
