目的:探讨基于欧洲医药保健网(Pharmaceutical Care Network Europe,PCNE)分类系统9.0版的全程药学监护在治疗脑梗死患者中的应用价值。方法:选取2020年10月—2022年3月上海市浦东新区光明中医医院收治的400例脑梗死患者作为研究对象,...目的:探讨基于欧洲医药保健网(Pharmaceutical Care Network Europe,PCNE)分类系统9.0版的全程药学监护在治疗脑梗死患者中的应用价值。方法:选取2020年10月—2022年3月上海市浦东新区光明中医医院收治的400例脑梗死患者作为研究对象,将其随机分为PCNE组(n=200)和传统组(n=200),传统组给予传统干预,PCNE组在此基础上给予基于PCNE分类系统9.0版的全程药学监护,比较两组药物相关性问题(Drug Related Problems,DRPs)、用药依从性(Morisky评分)、疾病复发率。结果:PCNE组DRPs发生率和产生原因占比均高于传统组,差异均有统计学意义(χ^(2)=23.169、32.063,P值均<0.01);PCNE组用药依从率高于传统组,差异无统计学意义(χ^(2)=5.659,P>0.05);PCNE组6个月疾病复发率低于传统组,差异无统计学意义(χ^(2)=4.810,P>0.05)。结论:基于PCNE分类系统9.0版的全程药学监护可改善脑梗死患者的DRPs和用药依从性,有利于降低疾病复发率,值得临床推广。展开更多
Background: The iStent inject is a Micro-Invasive Glaucoma Surgical (MIGS) device that has shown to reduce IOP and to be safe for glaucoma patients with fewer complications than regular surgery. Objective: To investig...Background: The iStent inject is a Micro-Invasive Glaucoma Surgical (MIGS) device that has shown to reduce IOP and to be safe for glaucoma patients with fewer complications than regular surgery. Objective: To investigate, up to 15 - 20 months, the efficacy and safety of implantation of two second-generation trabecular microbypass stents in patients with or without prior glaucoma surgery. Methods: Fifty-seven eyes were implanted with the iStent inject. The population was comprised of eyes with primary open-angle glaucoma (n = 51), pseudoexfoliation glaucoma (n = 5) and ocular hypertension (n = 1). Major outcome parameters included IOP, medication needs and corrected distance visual acuity (CDVA). Follow-up time points were one day, 2 - 4 months, 9 - 14 months and 15 - 20 months. Results: The main reason to perform MIGS was IOP reduction in 68.4%, reduced number of medications due to drug intolerance in 24.6% and reduced medication due to compliance issues in 7.0% of the eyes. IOP decreased by 22.47%, from 19.40 ± 3.83 mmHg preoperatively (preop) to 15.04 ± 1.67 mmHg at 15-20 months postoperatively. IOP reduction was achieved at all follow-up time points (p Conclusions: Insertion of the iStent inject in patients with or without prior glaucoma surgery shows effective and sustained improvements in IOP with no safety concerns.展开更多
It is of important significance to make studies on the sur-face electric characteristics of flake graphite and their variation law for strengthening the floatation of flake graphite.In this paper, DPM type microelectr...It is of important significance to make studies on the sur-face electric characteristics of flake graphite and their variation law for strengthening the floatation of flake graphite.In this paper, DPM type microelectrophoresis apparatus is used to de-termine the surface Zeta-potential of flake graphite pure mineral, study the affection of pulp pH value, seueral kinds of inorganic salt ions and anion surface activation agent (petroleum sodium sulfonate ) on flake graphite surface Zeta-potential,and explore the surface absorption charac-teristics of graphite.The floatation experiment of flake graphite pure mineral shows that both the petroleum sodium sulfonate and inorganic salt can strengthen the conventional floatation of flake graphite. The surface characteristic varia-tion caused by them is also an important factor to promote graphite floata-tion.展开更多
文摘目的:探讨基于欧洲医药保健网(Pharmaceutical Care Network Europe,PCNE)分类系统9.0版的全程药学监护在治疗脑梗死患者中的应用价值。方法:选取2020年10月—2022年3月上海市浦东新区光明中医医院收治的400例脑梗死患者作为研究对象,将其随机分为PCNE组(n=200)和传统组(n=200),传统组给予传统干预,PCNE组在此基础上给予基于PCNE分类系统9.0版的全程药学监护,比较两组药物相关性问题(Drug Related Problems,DRPs)、用药依从性(Morisky评分)、疾病复发率。结果:PCNE组DRPs发生率和产生原因占比均高于传统组,差异均有统计学意义(χ^(2)=23.169、32.063,P值均<0.01);PCNE组用药依从率高于传统组,差异无统计学意义(χ^(2)=5.659,P>0.05);PCNE组6个月疾病复发率低于传统组,差异无统计学意义(χ^(2)=4.810,P>0.05)。结论:基于PCNE分类系统9.0版的全程药学监护可改善脑梗死患者的DRPs和用药依从性,有利于降低疾病复发率,值得临床推广。
文摘Background: The iStent inject is a Micro-Invasive Glaucoma Surgical (MIGS) device that has shown to reduce IOP and to be safe for glaucoma patients with fewer complications than regular surgery. Objective: To investigate, up to 15 - 20 months, the efficacy and safety of implantation of two second-generation trabecular microbypass stents in patients with or without prior glaucoma surgery. Methods: Fifty-seven eyes were implanted with the iStent inject. The population was comprised of eyes with primary open-angle glaucoma (n = 51), pseudoexfoliation glaucoma (n = 5) and ocular hypertension (n = 1). Major outcome parameters included IOP, medication needs and corrected distance visual acuity (CDVA). Follow-up time points were one day, 2 - 4 months, 9 - 14 months and 15 - 20 months. Results: The main reason to perform MIGS was IOP reduction in 68.4%, reduced number of medications due to drug intolerance in 24.6% and reduced medication due to compliance issues in 7.0% of the eyes. IOP decreased by 22.47%, from 19.40 ± 3.83 mmHg preoperatively (preop) to 15.04 ± 1.67 mmHg at 15-20 months postoperatively. IOP reduction was achieved at all follow-up time points (p Conclusions: Insertion of the iStent inject in patients with or without prior glaucoma surgery shows effective and sustained improvements in IOP with no safety concerns.
文摘It is of important significance to make studies on the sur-face electric characteristics of flake graphite and their variation law for strengthening the floatation of flake graphite.In this paper, DPM type microelectrophoresis apparatus is used to de-termine the surface Zeta-potential of flake graphite pure mineral, study the affection of pulp pH value, seueral kinds of inorganic salt ions and anion surface activation agent (petroleum sodium sulfonate ) on flake graphite surface Zeta-potential,and explore the surface absorption charac-teristics of graphite.The floatation experiment of flake graphite pure mineral shows that both the petroleum sodium sulfonate and inorganic salt can strengthen the conventional floatation of flake graphite. The surface characteristic varia-tion caused by them is also an important factor to promote graphite floata-tion.
