The application of intelligent sensors in medical research:a review

The rapid advancement of biomedicine in the twenty-first century has been facilitated by the constant innovation in biomedical technology.The most crucial issue in the field of medicine is to use sensor technology to gather information from primitive organisms,particularly the human body.Design,development,and application of biomedical sensors in the study of clinical diseases’diagnosis and therapy have all been significantly aided by the advancement of medicine.The interest in creating sensors significantly increased in the 1960s.Chemical and biological sensors have been swiftly created in response to an urgent practical necessity,enabling the creation of selective sensors for the direct detection of diverse ions and compounds.The traditional large-size sensors are quickly turning into miniature sensors and are rapidly applied in biological and medical fields.Currently,wearable electronic blood pressure monitors,home blood glucose meters,and quick body surface digital thermometers are commonly used.The advent of a wide variety of medical-grade wearable sensors that will enable real-time biometric data tracking of a large range of physiological characteristics will likely be one of the most revolutionary,exciting,and difficult changes to come to medicine over the next several years.For possible uses in the entertainment,health monitoring,and medical care industries,high-performance flexible strain sensors connected to clothing or human skin are necessary.The use of sensors in the development of biomedical diagnostic tools and medical equipment will enhance human quality of life in the twenty-first century.This article will introduce the current medical sensor field related to sensors for physical quantities,sensors for chemical quantities,sensors for biological quantities such as electronic nose,electronic tongue,and their applications.

Progresses in Integrated Traditional Chinese and Western Medical Research on Reproductive Immunology

Reproductive immunology is a crossed subject of reproductive biology and immunobiology. Great progresses have been achieved in the subject along with the deep development in life science. Modern reproductive immunology includes immunological regulation of fertility, materno-fetal immuno-regu-lation, and neuro-reproductive endocrino-immune network. With the integrated traditional Chinese and western medicine (ICWM) applied to reproductive immunology it has been greatly enriched in research contents and depth. The present review is to introduce the recent progresses in research of integrated medicine on reproductive immunology.

Medical Research Council (UK)

Introduction The Medical Research Council （MRC） is a publicly-funded agency responsible for co-ordinating and funding medical research in the United Kingdom. The MRC is one of seven Research Councils in the UK and is answerable to, although politically independent from, the Department for Business, Innovation and Skills. The organisation is dedicated to ＂improving human health through world-class medical research＂. Since it was first established in 1920, the MRC has been able to accept charitable bequests, endowments and donations from the public to contribute towards the costs of the research that it undertakes. The MRC registered these charitable funds with the Charity Commission in the late 1960＇s and its charity- the Medical Research Foundation-has been successfully supporting medical research for over 80 years.

Introduction to Military Medical Research

Military Medical Research(MMR;ISSN 2095-7467,eISSN 2054-9369,CN 10-2094/R),an Open Access international journal,publishes cutting-edge findings on clinical research and basic medical sciences topics,with special focus on military medicine related subjects.Article types included in MMR are:Research Articles,Research Highlights,Case Reports,Commentaries,Letters to the Editor。

Introduction to Military Medical Research

Military Medical Research(MMR;ISSN 2095-7467,eISSN 2054-9369,CN 10-2094/R),an Open Access international journal,publishes cutting-edge findings on clinical research and basic medical sciences topics,with special focus on military medicine related subjects.Article types included in MMR are:Editorial,Research Highlights,

The National Health and Medical Research Council

Introduction The National Health and Medical Research Council （NHMRC） is Australia＇s leading expert body promoting the development and maintenance of public and individual health standards. NHMRC brings together within a single national organisation the functions of research funding and development of advice. One of its strengths is that it draws upon the resources of all components of the health system, including governments, medical practitioners, nurses and allied health professionals, researchers, teaching and research institutions, public and private program managers service administrators, community health organisations, social health researchers and consumers.

Introduction to Military Medical Research

Military Medical Research(MMR;ISSN 2095-7467,eISSN 2054-9369,CN 10-2094/R),an Open Access international journal,publishes cutting-edge findings on clinical research and basic medical sciences topics,with special focus on military medicine related subjects.Article types included in MMR are:Research Articles,Research Highlights,Case Reports,Commentaries,Letters to the Editor,Methodology Articles,Perspectives,Position articles and Guidelines,Reviews and

Introduction to Military Medical Research

Military Medical Research is an open access,peer-reviewed journal publishing cutting-edge findings on basic medical science and clinical research that is related to military medicine.The journal aims to combine advances in both civilian and military medicine,so as to provide up-to-date medical discussions and guidelines tailored towards application in military settings.

About Military Medical Research

Overview Military Medical Research is an open access,peer-reviewed journal publishing cut ing-edge i ndings on basic medical science and important clinical research that is related to military medicine.Open access All articles published by Military Medical Research are made freely and permanently accessible online immediately upon publication,without subscription charges or registration barriers.Every peer-reviewed research article appearing in any journal published by Bio Med Central is’open access’,meaning that:

Introduction to Military Medical Research

Military Medical Research is an open access,peer-reviewed journal publishing cutting-edge findings on basic medical science and clinical research that is related to military medicine.The journal aims to combine advances in both civilian and military medicine,so as to provide up-to-date medical discussions and guidelines tailored towards application in military settings.

Promotion of library management and book circulation to research on medical research

With the acceleration of the process of social information, information resources construction has become an important part of national development strategies. The library is one of the main information resources constructions and is an important information resource position of social construction. Computer applications in the book management, greatly improve the management efficiency of the library, and have changed the traditional management service model. Universal service network extends to every comer make reader can read everywhere, breaking the boundaries of time and space and also greatly promoting the modernization of the library. Library modernization, according to the characteristics of the objective law refers library work practices, uses modem technological conditions, rational organization of scientific management of library work, to maximize efficiency and quality and effectively complete the task library. Library essence of modem management techniques is to achieve the modernization of libraries and library management modernization. Modem library information system can be divided into three aspects of building automation libraries, library networks and digital libraries. Digital library management directly reflects a country＇ s level of a regional knowledge economy and information industry development, and digital network resource management in the book gradually dominates.

A Critical Review of “Genre Analysis:Structural and Linguistic Evolution of the English-medium Medical Research Article(1985–2004)”

This paper critically analyzes the article"Genre analysis: Structural and linguistic evolution of the English-medium medical research article(1985–2004)". It presents critique from three aspects: the data, the analysis method, and the conclusion part.

World Medical Association Declaration of HelsinkiE thical Principles for Medical Research Involving Human Subjects

Document Of World Medical AssociationWorld medical association declaration of Helsinki Ethical principles for medical research involving human subjects

The 2016 Lasker-DeBakey Clinical Medical Research Award: Innovative hepatitis C virus(HCV) replicons leading to drug development for hepatitis C cure

The 2016 Lasker-DeBakey Clinical Medical Research Award was given to three scientists working on different stages of the translational sciences on bringing a high efficacious therapy against hepatitis C virus （HCV） infection to a reality. An effective treatment of HCV chronic infection was developed, by a team led by Michael Sofia, using a prodrug approach and the drug PSI-7977 or Sofosbuvir was approved in 2013 less than 28 years after the initial discovery of HCV.

The 2016 Albert Lasker Basic Medical Research Award: Oxygen sensing—a mysterious process essential for survival

The 2016 Albert Lasker Basic Medical Research Award honors three physician-scientists： William G. Kaelin, Jr. from Harvard Medical School, Peter J. Ratcliffe from Uni- versity of Oxford and Gregg L. Semenza, from Johns Hopkins University School of Medicine, for their discovery of the pathway by which cells from human and most animals sense and adapt to changes in oxygen availability, a process essential for survival. The Lasker Award is widely considered as America＇s mosLt prestigious honor in the biomedical field. For 71 years,

Pushing the frontiers of military medical excellence:updates,progress and future needs

Since its establishment in 2014,Military Medical Research has come a long way in becoming a premier journal for scientific articles from various different specialties,with a special emphasis on topics with military relevance.The field of military medicine may be obscure,and may not be readily encountered by the typical clinician on a day-today basis.This journal aims not only to pursue excellence in military research,but also to keep current with the latest advancements on general medical topics from each and every specialty.This editorial serves to recap and synthesize the existing progress,updates and future needs of military medical excellence,discussing foremostly the unique traits of literature published in this journal,and subsequently presenting the discourse regarding wartime and peacetime medicine,the role of the military in a public health emergency,as well as wound healing and organ regeneration.Special attention has been devoted to military topics to shed light on the effects of Chemical,Biological,Radiological and Explosive warfare,environmental medicine and military psychiatry,topics which rarely have a chance to be discussed elsewhere.The interconnectedness between military combat and soldier physical and mental well-being is intricate,and has been distorted by pandemics such as coronavirus disease 2019(COVID-19).This journal has come a long way since its first article was published,steadily contributing to the existing knowledge pool on general medical topics with a military slant.Only with continuous research and sharing,can we build upon the work of the scientific community,with hopes for the betterment of patient care.

Severe Acute Respiratory Syndrome Coronavirus 2 Virus-Like Particle and Its Application in Chinese Medical Research

Background:The global outbreak of coronavirus disease 2019(COVID-19)has brought disastrous consequences to public health and medical systems,whereas no approved medications are currently available.Benefits of traditional Chinese medicine(TCM)against COVID-19 have been observed,however,the underlying mechanistic actions remain unclarified.Due to high pathogenicity and infectivity of the new coronavirus(severe acute respiratory syndrome coronavirus 2[SARS-CoV-2]),the lack of access to SARS-CoV-2 and biosafety level 3(P3)facilities has impeded scientific investigations of TCM against COVID-19.Though low-pathogenic coronavirus and pseudoviral systems have been applied to substitute SARS-CoV-2 in fundamental studies,both models cannot imitate virological and clinical features associated with SARS-CoV-2.The virus-like particle(VLP)is a virological model that is safe and could be performed without biosafety protections.Aims and Objectives:To construct VLP of SARS-CoV-2 containing structural proteins of authentic viruses and resembling the morphology,partial life cycle,and immunoreactions of natural virions,and to introduce VLP into Chinese medical research.Materials and Methods:Using mammalian expression system,we have currently constructed SARS-CoV-2 VLP containing four essential structural proteins.Results:Based on this model,we propose six aspects of research that could be carried out for TCM formulas in the fight against COVID-19.Conclusion:Application of the VLP model provides a safe methodology to strengthen the response systems of Chinese medicine in preventing and controlling newly identified infectious diseases and offers collaborative opportunities for interdisciplinary deciphering of molecular and biological basis of anti-viral TCM formulas.

Persist in and Carry Forward the Integrative Medical Research——Speech at the 6th National General Congress of Chinese Association of Integrative Medicine by Academician CHEN Zhu,Minister of Ministry of Health

The 6th National General Congress of Chinese Association of Integrative Medicine （CALM） was convened at 19-20, April 2008 in Beijing. Academician CHEN Zhu, the minister of Ministry of Health indicated at the congress that the integration of Chinese and Western medicine is very well in keeping with the situation of our country and the general rule of development in medical science; and as a good integration of Chinese medicine and Western medicine, it is mutually beneficial and advantageous to both of them. Seeing the creativity shown in integrative medical investigation in theoretic and methodological sides, we should and must persist in and develop it.

2011 Lasker Clinical Medical Research Award Honors Prof.TU You-you for the Discovery of Artemisinin

The 2011 Lasker Clinical Medical Research Award honors a scientist who discovered artemisinin and its utility for treating malaria. Prof. TU You-you （China Academy of Chinese Medical Sciences, Beijing） transformed an ancient Chinese healing method into the most powerful antimalarial medicine currently available that has saved millions of lives across the globe, especially in the developing world. An artemisinin-based drug combination is now the standard regimen for malaria recommended by the World Health Organization （WHO）.

Present Situation and Thinking of the Evaluation and Management of Biomedical Projects in Shenzhen Industrial Park of Shenzhen-Hong Kong Cooperation Zone

Objective To put forward some suggestions for the improvement of the evaluation system of Shenzhen Industrial Park of Shenzhen-Hong Kong Innovation Cooperation Zone by studying the scientific research project evaluation and management system of Japan Agency for Medical Research and Development(AMED).Methods Through literature review,lessons were drawn from the review and management policies and methods of biomedical projects implemented by Japan AMED.Then some reference was provided to the review and management of the projects in Shenzhen Industrial Park.Results and Conclusion A basic review framework has been set up in Shenzhen Industrial Park,which consists of scientific research management institution of Shenzhen Industrial Park,Third-Party Review Institution and Science Committee.However,there are three problems in this system:unclear selection criteria of review experts,insufficient supervision and lack of project evaluation standards.These problems can be solved by establishing an expert think tank,setting up graded project supervisors to have the dynamic monitoring,and developing a general evaluation scale for evaluating scientific research projects in Shenzhen Industrial Park.