Robust zero-watermarking algorithm based on discrete wavelet transform and daisy descriptors for encrypted medical image

In the intricate network environment,the secure transmission of medical images faces challenges such as information leakage and malicious tampering,significantly impacting the accuracy of disease diagnoses by medical professionals.To address this problem,the authors propose a robust feature watermarking algorithm for encrypted medical images based on multi-stage discrete wavelet transform(DWT),Daisy descriptor,and discrete cosine transform(DCT).The algorithm initially encrypts the original medical image through DWT-DCT and Logistic mapping.Subsequently,a 3-stage DWT transformation is applied to the encrypted medical image,with the centre point of the LL3 sub-band within its low-frequency component serving as the sampling point.The Daisy descriptor matrix for this point is then computed.Finally,a DCT transformation is performed on the Daisy descriptor matrix,and the low-frequency portion is processed using the perceptual hashing algorithm to generate a 32-bit binary feature vector for the medical image.This scheme utilises cryptographic knowledge and zero-watermarking technique to embed watermarks without modifying medical images and can extract the watermark from test images without the original image,which meets the basic re-quirements of medical image watermarking.The embedding and extraction of water-marks are accomplished in a mere 0.160 and 0.411s,respectively,with minimal computational overhead.Simulation results demonstrate the robustness of the algorithm against both conventional attacks and geometric attacks,with a notable performance in resisting rotation attacks.

Fractional-order heterogeneous memristive Rulkov neuronal network and its medical image watermarking application

This article proposes a novel fractional heterogeneous neural network by coupling a Rulkov neuron with a Hopfield neural network(FRHNN),utilizing memristors for emulating neural synapses.The study firstly demonstrates the coexistence of multiple firing patterns through phase diagrams,Lyapunov exponents(LEs),and bifurcation diagrams.Secondly,the parameter related firing behaviors are described through two-parameter bifurcation diagrams.Subsequently,local attraction basins reveal multi-stability phenomena related to initial values.Moreover,the proposed model is implemented on a microcomputer-based ARM platform,and the experimental results correspond to the numerical simulations.Finally,the article explores the application of digital watermarking for medical images,illustrating its features of excellent imperceptibility,extensive key space,and robustness against attacks including noise and cropping.

Marine Predators Algorithm with Deep Learning-Based Leukemia Cancer Classification on Medical Images

In blood or bone marrow,leukemia is a form of cancer.A person with leukemia has an expansion of white blood cells(WBCs).It primarily affects children and rarely affects adults.Treatment depends on the type of leukemia and the extent to which cancer has established throughout the body.Identifying leukemia in the initial stage is vital to providing timely patient care.Medical image-analysis-related approaches grant safer,quicker,and less costly solutions while ignoring the difficulties of these invasive processes.It can be simple to generalize Computer vision(CV)-based and image-processing techniques and eradicate human error.Many researchers have implemented computer-aided diagnosticmethods andmachine learning(ML)for laboratory image analysis,hopefully overcoming the limitations of late leukemia detection and determining its subgroups.This study establishes a Marine Predators Algorithm with Deep Learning Leukemia Cancer Classification(MPADL-LCC)algorithm onMedical Images.The projectedMPADL-LCC system uses a bilateral filtering(BF)technique to pre-process medical images.The MPADL-LCC system uses Faster SqueezeNet withMarine Predators Algorithm(MPA)as a hyperparameter optimizer for feature extraction.Lastly,the denoising autoencoder(DAE)methodology can be executed to accurately detect and classify leukemia cancer.The hyperparameter tuning process using MPA helps enhance leukemia cancer classification performance.Simulation results are compared with other recent approaches concerning various measurements and the MPADL-LCC algorithm exhibits the best results over other recent approaches.

DCFNet:An Effective Dual-Branch Cross-Attention Fusion Network for Medical Image Segmentation

Automatic segmentation of medical images provides a reliable scientific basis for disease diagnosis and analysis.Notably,most existing methods that combine the strengths of convolutional neural networks(CNNs)and Transformers have made significant progress.However,there are some limitations in the current integration of CNN and Transformer technology in two key aspects.Firstly,most methods either overlook or fail to fully incorporate the complementary nature between local and global features.Secondly,the significance of integrating the multiscale encoder features from the dual-branch network to enhance the decoding features is often disregarded in methods that combine CNN and Transformer.To address this issue,we present a groundbreaking dual-branch cross-attention fusion network(DCFNet),which efficiently combines the power of Swin Transformer and CNN to generate complementary global and local features.We then designed the Feature Cross-Fusion(FCF)module to efficiently fuse local and global features.In the FCF,the utilization of the Channel-wise Cross-fusion Transformer(CCT)serves the purpose of aggregatingmulti-scale features,and the Feature FusionModule(FFM)is employed to effectively aggregate dual-branch prominent feature regions from the spatial perspective.Furthermore,within the decoding phase of the dual-branch network,our proposed Channel Attention Block(CAB)aims to emphasize the significance of the channel features between the up-sampled features and the features generated by the FCFmodule to enhance the details of the decoding.Experimental results demonstrate that DCFNet exhibits enhanced accuracy in segmentation performance.Compared to other state-of-the-art(SOTA)methods,our segmentation framework exhibits a superior level of competitiveness.DCFNet’s accurate segmentation of medical images can greatly assist medical professionals in making crucial diagnoses of lesion areas in advance.

Research on Multi-Scale Feature Fusion Network Algorithm Based on Brain Tumor Medical Image Classification

Gliomas have the highest mortality rate of all brain tumors.Correctly classifying the glioma risk period can help doctors make reasonable treatment plans and improve patients’survival rates.This paper proposes a hierarchical multi-scale attention feature fusion medical image classification network(HMAC-Net),which effectively combines global features and local features.The network framework consists of three parallel layers:The global feature extraction layer,the local feature extraction layer,and the multi-scale feature fusion layer.A linear sparse attention mechanism is designed in the global feature extraction layer to reduce information redundancy.In the local feature extraction layer,a bilateral local attention mechanism is introduced to improve the extraction of relevant information between adjacent slices.In the multi-scale feature fusion layer,a channel fusion block combining convolutional attention mechanism and residual inverse multi-layer perceptron is proposed to prevent gradient disappearance and network degradation and improve feature representation capability.The double-branch iterative multi-scale classification block is used to improve the classification performance.On the brain glioma risk grading dataset,the results of the ablation experiment and comparison experiment show that the proposed HMAC-Net has the best performance in both qualitative analysis of heat maps and quantitative analysis of evaluation indicators.On the dataset of skin cancer classification,the generalization experiment results show that the proposed HMAC-Net has a good generalization effect.

A review of medical ocular image segmentation

Deep learning has been extensively applied to medical image segmentation,resulting in significant advancements in the field of deep neural networks for medical image segmentation since the notable success of U Net in 2015.However,the application of deep learning models to ocular medical image segmentation poses unique challenges,especially compared to other body parts,due to the complexity,small size,and blurriness of such images,coupled with the scarcity of data.This article aims to provide a comprehensive review of medical image segmentation from two perspectives:the development of deep network structures and the application of segmentation in ocular imaging.Initially,the article introduces an overview of medical imaging,data processing,and performance evaluation metrics.Subsequently,it analyzes recent developments in U-Net-based network structures.Finally,for the segmentation of ocular medical images,the application of deep learning is reviewed and categorized by the type of ocular tissue.

Importance-aware 3D volume visualization for medical content-based image retrieval-a preliminary study

Background A medical content-based image retrieval(CBIR)system is designed to retrieve images from large imaging repositories that are visually similar to a user′s query image.CBIR is widely used in evidence-based diagnosis,teaching,and research.Although the retrieval accuracy has largely improved,there has been limited development toward visualizing important image features that indicate the similarity of retrieved images.Despite the prevalence of 3D volumetric data in medical imaging such as computed tomography(CT),current CBIR systems still rely on 2D cross-sectional views for the visualization of retrieved images.Such 2D visualization requires users to browse through the image stacks to confirm the similarity of the retrieved images and often involves mental reconstruction of 3D information,including the size,shape,and spatial relations of multiple structures.This process is time-consuming and reliant on users'experience.Methods In this study,we proposed an importance-aware 3D volume visualization method.The rendering parameters were automatically optimized to maximize the visibility of important structures that were detected and prioritized in the retrieval process.We then integrated the proposed visualization into a CBIR system,thereby complementing the 2D cross-sectional views for relevance feedback and further analyses.Results Our preliminary results demonstrate that 3D visualization can provide additional information using multimodal positron emission tomography and computed tomography(PETCT)images of a non-small cell lung cancer dataset.

ATFF: Advanced Transformer with Multiscale Contextual Fusion for Medical Image Segmentation

Deep convolutional neural network (CNN) greatly promotes the automatic segmentation of medical images. However, due to the inherent properties of convolution operations, CNN usually cannot establish long-distance interdependence, which limits the segmentation performance. Transformer has been successfully applied to various computer vision, using self-attention mechanism to simulate long-distance interaction, so as to capture global information. However, self-attention lacks spatial location and high-performance computing. In order to solve the above problems, we develop a new medical transformer, which has a multi-scale context fusion function and can be used for medical image segmentation. The proposed model combines convolution operation and attention mechanism to form a u-shaped framework, which can capture both local and global information. First, the traditional converter module is improved to an advanced converter module, which uses post-layer normalization to obtain mild activation values, and uses scaled cosine attention with a moving window to obtain accurate spatial information. Secondly, we also introduce a deep supervision strategy to guide the model to fuse multi-scale feature information. It further enables the proposed model to effectively propagate feature information across layers, Thanks to this, it can achieve better segmentation performance while being more robust and efficient. The proposed model is evaluated on multiple medical image segmentation datasets. Experimental results demonstrate that the proposed model achieves better performance on a challenging dataset (ETIS) compared to existing methods that rely only on convolutional neural networks, transformers, or a combination of both. The mDice and mIou indicators increased by 2.74% and 3.3% respectively.

BeFOI: A Novel Method Based on Conditional Diffusion Model for Medical Image Denoising

The progress in medical imaging technology highlights the importance of image quality for effective diagnosis and treatment.Yet,noise during capture and transmission can compromise image accuracy and reliability,complicating clinical decisions.The rising interest in diffusion models has led to their exploration of denoising images.We present Be-FOI(Better Fluoro Images),a weakly supervised model that uses cine images to denoise fluoroscopic images,both DR types.Trained through precise noise estimation and simulation,BeFOI employs Markov chains to denoise using only the fluoroscopic image as guidance.Our tests show that BeFOI outperforms other methods,reducing noise and enhancing clar-ity and diagnostic utility,making it an effective post-processing tool for medical images.

MI-STEG:A Medical Image Steganalysis Framework Based on Ensemble Deep Learning

Medical image steganography aims to increase data security by concealing patient-personal information as well as diagnostic and therapeutic data in the spatial or frequency domain of radiological images.On the other hand,the discipline of image steganalysis generally provides a classification based on whether an image has hidden data or not.Inspired by previous studies on image steganalysis,this study proposes a deep ensemble learning model for medical image steganalysis to detect malicious hidden data in medical images and develop medical image steganography methods aimed at securing personal information.With this purpose in mind,a dataset containing brain Magnetic Resonance(MR)images of healthy individuals and epileptic patients was built.Spatial Version of the Universal Wavelet Relative Distortion(S-UNIWARD),Highly Undetectable Stego(HUGO),and Minimizing the Power of Optimal Detector(MIPOD)techniques used in spatial image steganalysis were adapted to the problem,and various payloads of confidential data were hidden in medical images.The architectures of medical image steganalysis networks were transferred separately from eleven Dense Convolutional Network(DenseNet),Residual Neural Network(ResNet),and Inception-based models.The steganalysis outputs of these networks were determined by assembling models separately for each spatial embedding method with different payload ratios.The study demonstrated the success of pre-trained ResNet,DenseNet,and Inception models in the cover-stego mismatch scenario for each hiding technique with different payloads.Due to the high detection accuracy achieved,the proposed model has the potential to lead to the development of novel medical image steganography algorithms that existing deep learning-based steganalysis methods cannot detect.The experiments and the evaluations clearly proved this attempt.

Deep Learning for Image Segmentation: A Focus on Medical Imaging

Image segmentation is crucial for various research areas. Manycomputer vision applications depend on segmenting images to understandthe scene, such as autonomous driving, surveillance systems, robotics, andmedical imaging. With the recent advances in deep learning (DL) and itsconfounding results in image segmentation, more attention has been drawnto its use in medical image segmentation. This article introduces a surveyof the state-of-the-art deep convolution neural network (CNN) models andmechanisms utilized in image segmentation. First, segmentation models arecategorized based on their model architecture and primary working principle.Then, CNN categories are described, and various models are discussed withineach category. Compared with other existing surveys, several applicationswith multiple architectural adaptations are discussed within each category.A comparative summary is included to give the reader insights into utilizedarchitectures in different applications and datasets. This study focuses onmedical image segmentation applications, where the most widely used architecturesare illustrated, and other promising models are suggested that haveproven their success in different domains. Finally, the present work discussescurrent limitations and solutions along with future trends in the field.

Application of U-Net and Optimized Clustering in Medical Image Segmentation:A Review

As a mainstream research direction in the field of image segmentation,medical image segmentation plays a key role in the quantification of lesions,three-dimensional reconstruction,region of interest extraction and so on.Compared with natural images,medical images have a variety of modes.Besides,the emphasis of information which is conveyed by images of different modes is quite different.Because it is time-consuming and inefficient to manually segment medical images only by professional and experienced doctors.Therefore,large quantities of automated medical image segmentation methods have been developed.However,until now,researchers have not developed a universal method for all types of medical image segmentation.This paper reviews the literature on segmentation techniques that have produced major breakthroughs in recent years.Among the large quantities of medical image segmentation methods,this paper mainly discusses two categories of medical image segmentation methods.One is the improved strategies based on traditional clustering method.The other is the research progress of the improved image segmentation network structure model based on U-Net.The power of technology proves that the performance of the deep learning-based method is significantly better than that of the traditional method.This paper discussed both advantages and disadvantages of different algorithms and detailed how these methods can be used for the segmentation of lesions or other organs and tissues,as well as possible technical trends for future work.

Dual-Branch-UNet: A Dual-Branch Convolutional Neural Network for Medical Image Segmentation

In intelligent perception and diagnosis of medical equipment,the visual and morphological changes in retinal vessels are closely related to the severity of cardiovascular diseases(e.g.,diabetes and hypertension).Intelligent auxiliary diagnosis of these diseases depends on the accuracy of the retinal vascular segmentation results.To address this challenge,we design a Dual-Branch-UNet framework,which comprises a Dual-Branch encoder structure for feature extraction based on the traditional U-Net model for medical image segmentation.To be more explicit,we utilize a novel parallel encoder made up of various convolutional modules to enhance the encoder portion of the original U-Net.Then,image features are combined at each layer to produce richer semantic data and the model’s capacity is adjusted to various input images.Meanwhile,in the lower sampling section,we give up pooling and conduct the lower sampling by convolution operation to control step size for information fusion.We also employ an attentionmodule in the decoder stage to filter the image noises so as to lessen the response of irrelevant features.Experiments are verified and compared on the DRIVE and ARIA datasets for retinal vessels segmentation.The proposed Dual-Branch-UNet has proved to be superior to other five typical state-of-the-art methods.

LGNet:Local and global representation learning for fast biomedical image segmentation

Medical image segmentation plays a crucial role in clinical diagnosis and therapy systems,yet still faces many challenges.Building on convolutional neural networks(CNNs),medical image segmentation has achieved tremendous progress.However,owing to the locality of convolution operations,CNNs have the inherent limitation in learning global context.To address the limitation in building global context relationship from CNNs,we propose LGNet,a semantic segmentation network aiming to learn local and global features for fast and accurate medical image segmentation in this paper.Specifically,we employ a two-branch architecture consisting of convolution layers in one branch to learn local features and transformer layers in the other branch to learn global features.LGNet has two key insights:(1)We bridge two-branch to learn local and global features in an interactive way;(2)we present a novel multi-feature fusion model(MSFFM)to leverage the global contexture information from transformer and the local representational features from convolutions.Our method achieves state-of-the-art trade-off in terms of accuracy and efficiency on several medical image segmentation benchmarks including Synapse,ACDC and MOST.Specifically,LGNet achieves the state-of-the-art performance with Dice's indexes of 80.15%on Synapse,of 91.70%on ACDC,and of 95.56%on MOST.Meanwhile,the inference speed attains at 172 frames per second with 224-224 input resolution.The extensive experiments demonstrate the effectiveness of the proposed LGNet for fast and accurate for medical image segmentation.

Zero Watermarking Algorithm for Medical Image Based on Resnet50-DCT

Medical images are used as a diagnostic tool, so protecting theirconfidentiality has long been a topic of study. From this, we propose aResnet50-DCT-based zero watermarking algorithm for use with medicalimages. To begin, we use Resnet50, a pre-training network, to draw out thedeep features of medical images. Then the deep features are transformedby DCT transform and the perceptual hash function is used to generatethe feature vector. The original watermark is chaotic scrambled to get theencrypted watermark, and the watermark information is embedded into theoriginal medical image by XOR operation, and the logical key vector isobtained and saved at the same time. Similarly, the same feature extractionmethod is used to extract the deep features of the medical image to be testedand generate the feature vector. Later, the XOR operation is carried outbetween the feature vector and the logical key vector, and the encryptedwatermark is extracted and decrypted to get the restored watermark;thenormalized correlation coefficient (NC) of the original watermark and therestored watermark is calculated to determine the ownership and watermarkinformation of the medical image to be tested. After calculation, most ofthe NC values are greater than 0.50. The experimental results demonstratethe algorithm’s robustness, invisibility, and security, as well as its ability toaccurately extract watermark information. The algorithm also shows goodresistance to conventional attacks and geometric attacks.

Image Color Rendering Based on Hinge-Cross-Entropy GAN in Internet of Medical Things

Computer-aided diagnosis based on image color rendering promotes medical image analysis and doctor-patient communication by highlighting important information of medical diagnosis.To overcome the limitations of the color rendering method based on deep learning,such as poor model stability,poor rendering quality,fuzzy boundaries and crossed color boundaries,we propose a novel hinge-cross-entropy generative adversarial network(HCEGAN).The self-attention mechanism was added and improved to focus on the important information of the image.And the hinge-cross-entropy loss function was used to stabilize the training process of GAN models.In this study,we implement the HCEGAN model for image color rendering based on DIV2K and COCO datasets,and evaluate the results using SSIM and PSNR.The experimental results show that the proposed HCEGAN automatically re-renders images,significantly improves the quality of color rendering and greatly improves the stability of prior GAN models.

Application of Zero-Watermarking for Medical Image in Intelligent Sensor Network Security

The field of healthcare is considered to be the most promising application of intelligent sensor networks.However,the security and privacy protection ofmedical images collected by intelligent sensor networks is a hot problem that has attracted more and more attention.Fortunately,digital watermarking provides an effective method to solve this problem.In order to improve the robustness of the medical image watermarking scheme,in this paper,we propose a novel zero-watermarking algorithm with the integer wavelet transform(IWT),Schur decomposition and image block energy.Specifically,we first use IWT to extract low-frequency information and divide them into non-overlapping blocks,then we decompose the sub-blocks by Schur decomposition.After that,the feature matrix is constructed according to the relationship between the image block energy and the whole image energy.At the same time,we encrypt watermarking with the logistic chaotic position scrambling.Finally,the zero-watermarking is obtained by XOR operation with the encrypted watermarking.Three indexes of peak signal-to-noise ratio,normalization coefficient(NC)and the bit error rate(BER)are used to evaluate the robustness of the algorithm.According to the experimental results,most of the NC values are around 0.9 under various attacks,while the BER values are very close to 0.These experimental results show that the proposed algorithm is more robust than the existing zero-watermarking methods,which indicates it is more suitable for medical image privacy and security protection.

TC-Fuse: A Transformers Fusing CNNs Network for Medical Image Segmentation

In medical image segmentation task,convolutional neural networks(CNNs)are difficult to capture long-range dependencies,but transformers can model the long-range dependencies effectively.However,transformers have a flexible structure and seldom assume the structural bias of input data,so it is difficult for transformers to learn positional encoding of the medical images when using fewer images for training.To solve these problems,a dual branch structure is proposed.In one branch,Mix-Feed-Forward Network(Mix-FFN)and axial attention are adopted to capture long-range dependencies and keep the translation invariance of the model.Mix-FFN whose depth-wise convolutions can provide position information is better than ordinary positional encoding.In the other branch,traditional convolutional neural networks(CNNs)are used to extract different features of fewer medical images.In addition,the attention fusion module BiFusion is used to effectively integrate the information from the CNN branch and Transformer branch,and the fused features can effectively capture the global and local context of the current spatial resolution.On the public standard datasets Gland Segmentation(GlaS),Colorectal adenocarcinoma gland(CRAG)and COVID-19 CT Images Segmentation,the F1-score,Intersection over Union(IoU)and parameters of the proposed TC-Fuse are superior to those by Axial Attention U-Net,U-Net,Medical Transformer and other methods.And F1-score increased respectively by 2.99%,3.42%and 3.95%compared with Medical Transformer.

Robust Multi-Watermarking Algorithm for Medical Images Based on GoogLeNet and Henon Map

The field of medical images has been rapidly evolving since the advent of the digital medical information era.However,medical data is susceptible to leaks and hacks during transmission.This paper proposed a robust multi-watermarking algorithm for medical images based on GoogLeNet transfer learning to protect the privacy of patient data during transmission and storage,as well as to increase the resistance to geometric attacks and the capacity of embedded watermarks of watermarking algorithms.First,a pre-trained GoogLeNet network is used in this paper,based on which the parameters of several previous layers of the network are fixed and the network is fine-tuned for the constructed medical dataset,so that the pre-trained network can further learn the deep convolutional features in the medical dataset,and then the trained network is used to extract the stable feature vectors of medical images.Then,a two-dimensional Henon chaos encryption technique,which is more sensitive to initial values,is used to encrypt multiple different types of watermarked private information.Finally,the feature vector of the image is logically operated with the encrypted multiple watermark information,and the obtained key is stored in a third party,thus achieving zero watermark embedding and blind extraction.The experimental results confirmthe robustness of the algorithm from the perspective ofmultiple types of watermarks,while also demonstrating the successful embedding ofmultiple watermarks for medical images,and show that the algorithm is more resistant to geometric attacks than some conventional watermarking algorithms.

Short‐term and long‐term memory self‐attention network for segmentation of tumours in 3D medical images

Tumour segmentation in medical images(especially 3D tumour segmentation)is highly challenging due to the possible similarity between tumours and adjacent tissues,occurrence of multiple tumours and variable tumour shapes and sizes.The popular deep learning‐based segmentation algorithms generally rely on the convolutional neural network(CNN)and Transformer.The former cannot extract the global image features effectively while the latter lacks the inductive bias and involves the complicated computation for 3D volume data.The existing hybrid CNN‐Transformer network can only provide the limited performance improvement or even poorer segmentation performance than the pure CNN.To address these issues,a short‐term and long‐term memory self‐attention network is proposed.Firstly,a distinctive self‐attention block uses the Transformer to explore the correlation among the region features at different levels extracted by the CNN.Then,the memory structure filters and combines the above information to exclude the similar regions and detect the multiple tumours.Finally,the multi‐layer reconstruction blocks will predict the tumour boundaries.Experimental results demonstrate that our method outperforms other methods in terms of subjective visual and quantitative evaluation.Compared with the most competitive method,the proposed method provides Dice(82.4%vs.76.6%)and Hausdorff distance 95%(HD95)(10.66 vs.11.54 mm)on the KiTS19 as well as Dice(80.2%vs.78.4%)and HD95(9.632 vs.12.17 mm)on the LiTS.