BACKGROUND Ankylosing spondylitis at total hip arthroplasty(THA)has significant hip stiffness with flexion deformity,restricted mobility,and function.Range of movement(ROM)improvement with good functional outcome is s...BACKGROUND Ankylosing spondylitis at total hip arthroplasty(THA)has significant hip stiffness with flexion deformity,restricted mobility,and function.Range of movement(ROM)improvement with good functional outcome is seen following THA in these hips.The modified Hardinge approach without abductor compromise is helpful in these stiff hips with associated flexion deformity.AIM To assess improvement in ROM and functional outcomes with a modified lateral approach THA in ankylosing spondylitis with stiff hips.METHODS A total of 69 hips that underwent THA with a modified Hardinge approach in 40 patients were evaluated at a mean follow-up of 38.33 mo.All individuals ambulated with weight-bearing as tolerated and ROM exercises from the 1st postoperative day.Modified Harris hip score and ROM were assessed during follow-up.Quality of life assessments using the 36-item and 12-item short form health surveys were done along with clinical and functional outcomes at followup.SPSS 22.0 was used for statistical analysis.The correlation of ROM and functional score change was performed using Pearson’s correlation coefficient.RESULTS Sixty-nine hips with a significant decrease in ROM preoperatively with 32 clinically fused hips showed significant improvement in flexion range.The mean flexion in 69 hips improved from 29.35±31.38 degrees to 102.17±10.48 degrees.The mean difference of 72.82 with a P value<0.0001 was significant.In total,45 out of 69 hips had flexion deformity,with 13 hips having a deformity above 30 degrees.The flexion during the follow-up was below 90 degrees in 3 hips.Eleven hips had flexion of 90 degrees at follow-up,while the remaining 55 hips had flexion above 100 degrees.Modified Harris hip score improved from 17.03±6.02 to 90.66±7.23(P value<0.0001).The 36-item short form health survey at the follow-up indicated health status in 40 patients as excellent in 11,very good in 20,good in 5,fair in 3,and poor in 1.The mean mental health score was 84.10±11.58.Pain relief was good in all 69 hips.Altogether,28/40 patients(70%)had no pain,9 patients(22%)had occasional pain,and 3 patients(8%)had mild to moderate pain with unusual activity.Heterotopic ossification was seen in 21 hips with Brooker class 1 in 14 hips.CONCLUSION Modified Hardinge approach THA in ankylosing spondylitis with stiff hips with flexion deformity significantly improved ROM,Harris hip score,and quality of life indicated by the 36-item and 12-item short form health surveys.展开更多
Aim: This work aimed to study the influence of two chronic health conditions, metabolic syndrome (MetS) and musculoskeletal disorders (MSDs), on the health-related quality of life (HRQoL) of Saudis. Method: The Medica...Aim: This work aimed to study the influence of two chronic health conditions, metabolic syndrome (MetS) and musculoskeletal disorders (MSDs), on the health-related quality of life (HRQoL) of Saudis. Method: The Medical Outcomes Study Short Form-36 (SF-36) health status questionnaire was used to measure the HRQoL and compare the mean scores of the questionnaire subscales and physical and mental component summaries (PCS and MCS) of 33 patients with MetS, 18 patients with MSDs, and 30 apparently healthy (AH) subjects. Regression analysis was used to measure the prediction power of the study group, age and gender of the participants in estimating the HRQoL. Results: Results showed that the mean scores of the physical subscales, the PCS, the mental subscales and MCS were arranged in descending order from AH subjects, patients with MetS, to patients with MSDs. The mean scores difference among the 3 study groups were statistically significant with the only exception for the general mental health (GMH) subscale (P = 0.404). The study group and age accounted for 41.8% of the variability of PCS while the study group accounted for 19.6% of the variability in the MCS. The resulted equation to estimate the PCS score was as follows: PCS = 113.18 - 12.85 (Group: 0 for AH, 1 for MetS, and 2 for MSDs) - 0.67 age. On the other hand the resulted equation to estimate the MCS score was as follows: MCS = 76.203 - 10.426 (Group: 0 for AH, 1 for MetS, and 2 for MSDs). Conclusion: Patients with MetS and patients with MSDs had lower HRQoL than AH subjects. All the physical and mental dimensions of HRQoL are negatively influenced with MetS and with MSDs with the only exception for the GMH subscale. The physical and mental burden of MSDs is more dominant. The study group and age can be used to predict the PCS while the study group can be used to predict the MCS.展开更多
BACKGROUND A large number of adults with long-term type 1 diabetes are affected by symmetrical peripheral neuropathy.These complications increase socioeconomic expenses and diminish the individual quality of life.The ...BACKGROUND A large number of adults with long-term type 1 diabetes are affected by symmetrical peripheral neuropathy.These complications increase socioeconomic expenses and diminish the individual quality of life.The 36-Item Short Form Health Survey(SF-36)is a generic patient reported questionnaire,measuring mental and physical health related quality of life.We hypothesized that diabetic neuropathy would decrease physical and mental quality of life measured with SF-36,and that clinical appearance may be associated with the decline.AIM To investigate if diabetic neuropathy would decrease physical and mental quality of life measured with SF-36,and if clinical appearance may be associated with the decline.METHODS Forty-eight adults[age 50±9 years,10 females,disease duration 32(14-51)years]with verified diabetic symmetrical peripheral neuropathy and 21 healthy participants(age 51±6 years,6 females)underwent standardised nerve conduction testing and completed the SF-36 questionnaire.Furthermore,disease duration,number of comorbidities,both diabetes related and nondiabetes related,vibration perception threshold,number of hypoglycaemic events,HbA1c and administration way of insulin was notified.RESULTS In comparison to healthy subjects,patients’mental composite score was not significantly diminished(51.9±8.9 vs 53.1±5.5,P=0.558),while the physical composite score was(46.3±11.7 vs 54.6±3.3,P=0.002).As expected,the overall physical health related symptoms in patients were associated to total number of comorbidities(P<0.0001),comorbidities relation to diabetes(P=0.0002)and HbA1c(P=0.005)as well as comorbidities not related to diabetes(P=0.0006).CONCLUSION The finding of this study emphasises the importance of focusing on quality of life in adults with diabetes and especially in those with multiple comorbidities as well as the possibility of HbA1c as a biomarker for severe complication.展开更多
目的调查肝硬化患者肝移植前后生存质量的变化情况。方法研究对象为在中山大学附属第三医院移植中心行首次肝移植手术的68例肝硬化患者。分别在术前,术后0～6个月、7～12个月、12个月以上对患者进行问卷调查。问卷采用健康调查简表(medi...目的调查肝硬化患者肝移植前后生存质量的变化情况。方法研究对象为在中山大学附属第三医院移植中心行首次肝移植手术的68例肝硬化患者。分别在术前,术后0～6个月、7～12个月、12个月以上对患者进行问卷调查。问卷采用健康调查简表(medical outcome study 36-item short form health survey,SF-36)与疾病专用调查表——慢性肝病问卷(chronic liver disease questionaire,CLDQ)。结果在肝移植术前,肝硬化患者的SF-36和CLDQ各维度评分均偏低。术后各时段SF-36的生理机能、躯体疼痛、一般健康、精力和CLDQ的腹部症状、乏力、全身症状、活动评分均较术前明显升高(均为P<0.05);与术前比较,术后0～6个月SF-36的生理职能、社会功能、情感职能、精神健康和CLDQ的情感功能、焦虑评分差异无统计学意义(均为P>0.05),但术后7～12个月、术后12个月以上述维度评分比较差异均有统计学意义(均为P<0.05);术后随着时间的推移,两表各维度得分逐步升高。结论肝硬化肝移植患者术后的生存质量与术前比较有明显改善,术后早期以生理功能方面改善明显,随时间的推移,生存质量其他指标如心理状态和社会功能也得到明显的改善。展开更多
目的了解京冀两地人群的饮酒模式现状,探究不同饮酒模式的特征及其生命质量的得分差异。方法选取“正常人群不同体质中医脉诊生理参数系统调查”数据库中符合条件的数据,依据日均纯酒精摄入量划分饮酒模式,通过简明健康状况调查问卷(med...目的了解京冀两地人群的饮酒模式现状,探究不同饮酒模式的特征及其生命质量的得分差异。方法选取“正常人群不同体质中医脉诊生理参数系统调查”数据库中符合条件的数据,依据日均纯酒精摄入量划分饮酒模式,通过简明健康状况调查问卷(medical outcomes study 36-item short-form health survey,SF-36)获得生命质量得分,采用最小二乘回归分析不同饮酒模式的生命质量得分差异。结果纳入样本1994例,其中男性654例,女性1340例;年龄为31.7(22.0,37.0)岁。不饮酒模式、前饮酒模式、适度饮酒模式、中度饮酒模式、重度饮酒模式分别有1375人、74人、368人、90人、87人。5种饮酒模式比较,性别、年龄、婚姻情况、学历、主观经济状况、家庭人均实际收入、家庭成员、BMI、家族史、合并慢性病、饮茶情况、吸烟情况、睡眠习惯、劳逸情况、运动习惯的组间差异均有统计学意义(均P<0.05)。控制混杂变量的结果显示,5种饮酒模式的SF-36总分、心理领域以及下属的社会功能、情感职能、精神健康维度得分组间差异均有统计学意义(均P<0.05)。差异性检验与最小临床重要差值共同表明,不饮酒模式的生命质量最好,重度饮酒模式次之,其次是中度、适度饮酒模式,前饮酒模式最差,尤其在心理领域及其下属维度。结论相较于不饮酒模式,前饮酒模式生命质量最差,重度饮酒模式得分虽高,但考虑到其他健康结局,建议人群减少饮酒或保持不饮酒,以获得较大的健康效益。展开更多
目的 了解某集团旗下养老院护理员的生命质量现状及其影响因素。方法 2022年2—4月随机抽取某集团位于深圳的3家养老院共153名护工,采用一般状况调查问卷和中文版36条简明健康状况调查表(the medical outcomes study36-item short form ...目的 了解某集团旗下养老院护理员的生命质量现状及其影响因素。方法 2022年2—4月随机抽取某集团位于深圳的3家养老院共153名护工,采用一般状况调查问卷和中文版36条简明健康状况调查表(the medical outcomes study36-item short form health survey,SF-36)对护理员进行自评量表式调查。利用Excel 2016软件和SPSS 26.0软件进行数据收集和解析,采用t检验、单因素方差分析、多元逐步回归分析进行统计学分析。结果 153名被调查者生命质量得分为(70.50±7.34)分,其中生理健康领域得分为(74.81±9.75)分,心理健康领域得分为(68.07±7.09)分。单因素方差分析和多元逐步回归分析显示,性别、婚姻状况、睡眠质量、饮食状况、薪酬满意度及是否上夜班均是影响养老院护工生命质量的主要影响因素(均P<0.05)。结论 养老院护理员的生命质量水平较低,需进一步提高。集团应适当提高护理团队的男性比例,加强对护理员的心理疏导,适当提高薪酬水平,完善绩效考核体系并提高绩效奖励,注重员工关怀,适当发放员工福利。展开更多
文摘BACKGROUND Ankylosing spondylitis at total hip arthroplasty(THA)has significant hip stiffness with flexion deformity,restricted mobility,and function.Range of movement(ROM)improvement with good functional outcome is seen following THA in these hips.The modified Hardinge approach without abductor compromise is helpful in these stiff hips with associated flexion deformity.AIM To assess improvement in ROM and functional outcomes with a modified lateral approach THA in ankylosing spondylitis with stiff hips.METHODS A total of 69 hips that underwent THA with a modified Hardinge approach in 40 patients were evaluated at a mean follow-up of 38.33 mo.All individuals ambulated with weight-bearing as tolerated and ROM exercises from the 1st postoperative day.Modified Harris hip score and ROM were assessed during follow-up.Quality of life assessments using the 36-item and 12-item short form health surveys were done along with clinical and functional outcomes at followup.SPSS 22.0 was used for statistical analysis.The correlation of ROM and functional score change was performed using Pearson’s correlation coefficient.RESULTS Sixty-nine hips with a significant decrease in ROM preoperatively with 32 clinically fused hips showed significant improvement in flexion range.The mean flexion in 69 hips improved from 29.35±31.38 degrees to 102.17±10.48 degrees.The mean difference of 72.82 with a P value<0.0001 was significant.In total,45 out of 69 hips had flexion deformity,with 13 hips having a deformity above 30 degrees.The flexion during the follow-up was below 90 degrees in 3 hips.Eleven hips had flexion of 90 degrees at follow-up,while the remaining 55 hips had flexion above 100 degrees.Modified Harris hip score improved from 17.03±6.02 to 90.66±7.23(P value<0.0001).The 36-item short form health survey at the follow-up indicated health status in 40 patients as excellent in 11,very good in 20,good in 5,fair in 3,and poor in 1.The mean mental health score was 84.10±11.58.Pain relief was good in all 69 hips.Altogether,28/40 patients(70%)had no pain,9 patients(22%)had occasional pain,and 3 patients(8%)had mild to moderate pain with unusual activity.Heterotopic ossification was seen in 21 hips with Brooker class 1 in 14 hips.CONCLUSION Modified Hardinge approach THA in ankylosing spondylitis with stiff hips with flexion deformity significantly improved ROM,Harris hip score,and quality of life indicated by the 36-item and 12-item short form health surveys.
文摘Aim: This work aimed to study the influence of two chronic health conditions, metabolic syndrome (MetS) and musculoskeletal disorders (MSDs), on the health-related quality of life (HRQoL) of Saudis. Method: The Medical Outcomes Study Short Form-36 (SF-36) health status questionnaire was used to measure the HRQoL and compare the mean scores of the questionnaire subscales and physical and mental component summaries (PCS and MCS) of 33 patients with MetS, 18 patients with MSDs, and 30 apparently healthy (AH) subjects. Regression analysis was used to measure the prediction power of the study group, age and gender of the participants in estimating the HRQoL. Results: Results showed that the mean scores of the physical subscales, the PCS, the mental subscales and MCS were arranged in descending order from AH subjects, patients with MetS, to patients with MSDs. The mean scores difference among the 3 study groups were statistically significant with the only exception for the general mental health (GMH) subscale (P = 0.404). The study group and age accounted for 41.8% of the variability of PCS while the study group accounted for 19.6% of the variability in the MCS. The resulted equation to estimate the PCS score was as follows: PCS = 113.18 - 12.85 (Group: 0 for AH, 1 for MetS, and 2 for MSDs) - 0.67 age. On the other hand the resulted equation to estimate the MCS score was as follows: MCS = 76.203 - 10.426 (Group: 0 for AH, 1 for MetS, and 2 for MSDs). Conclusion: Patients with MetS and patients with MSDs had lower HRQoL than AH subjects. All the physical and mental dimensions of HRQoL are negatively influenced with MetS and with MSDs with the only exception for the GMH subscale. The physical and mental burden of MSDs is more dominant. The study group and age can be used to predict the PCS while the study group can be used to predict the MCS.
基金Supported by Aalborg UniversityNovo Nordisk Scandinavia AS+2 种基金Empowering Industry and Research EIR Northern Jutlandduring the conduct of the studyInnovation Fund Denmark,Individuals,Disease and Society,Copenhagen,Denmark
文摘BACKGROUND A large number of adults with long-term type 1 diabetes are affected by symmetrical peripheral neuropathy.These complications increase socioeconomic expenses and diminish the individual quality of life.The 36-Item Short Form Health Survey(SF-36)is a generic patient reported questionnaire,measuring mental and physical health related quality of life.We hypothesized that diabetic neuropathy would decrease physical and mental quality of life measured with SF-36,and that clinical appearance may be associated with the decline.AIM To investigate if diabetic neuropathy would decrease physical and mental quality of life measured with SF-36,and if clinical appearance may be associated with the decline.METHODS Forty-eight adults[age 50±9 years,10 females,disease duration 32(14-51)years]with verified diabetic symmetrical peripheral neuropathy and 21 healthy participants(age 51±6 years,6 females)underwent standardised nerve conduction testing and completed the SF-36 questionnaire.Furthermore,disease duration,number of comorbidities,both diabetes related and nondiabetes related,vibration perception threshold,number of hypoglycaemic events,HbA1c and administration way of insulin was notified.RESULTS In comparison to healthy subjects,patients’mental composite score was not significantly diminished(51.9±8.9 vs 53.1±5.5,P=0.558),while the physical composite score was(46.3±11.7 vs 54.6±3.3,P=0.002).As expected,the overall physical health related symptoms in patients were associated to total number of comorbidities(P<0.0001),comorbidities relation to diabetes(P=0.0002)and HbA1c(P=0.005)as well as comorbidities not related to diabetes(P=0.0006).CONCLUSION The finding of this study emphasises the importance of focusing on quality of life in adults with diabetes and especially in those with multiple comorbidities as well as the possibility of HbA1c as a biomarker for severe complication.
文摘目的调查肝硬化患者肝移植前后生存质量的变化情况。方法研究对象为在中山大学附属第三医院移植中心行首次肝移植手术的68例肝硬化患者。分别在术前,术后0～6个月、7～12个月、12个月以上对患者进行问卷调查。问卷采用健康调查简表(medical outcome study 36-item short form health survey,SF-36)与疾病专用调查表——慢性肝病问卷(chronic liver disease questionaire,CLDQ)。结果在肝移植术前,肝硬化患者的SF-36和CLDQ各维度评分均偏低。术后各时段SF-36的生理机能、躯体疼痛、一般健康、精力和CLDQ的腹部症状、乏力、全身症状、活动评分均较术前明显升高(均为P<0.05);与术前比较,术后0～6个月SF-36的生理职能、社会功能、情感职能、精神健康和CLDQ的情感功能、焦虑评分差异无统计学意义(均为P>0.05),但术后7～12个月、术后12个月以上述维度评分比较差异均有统计学意义(均为P<0.05);术后随着时间的推移,两表各维度得分逐步升高。结论肝硬化肝移植患者术后的生存质量与术前比较有明显改善,术后早期以生理功能方面改善明显,随时间的推移,生存质量其他指标如心理状态和社会功能也得到明显的改善。
文摘目的了解京冀两地人群的饮酒模式现状,探究不同饮酒模式的特征及其生命质量的得分差异。方法选取“正常人群不同体质中医脉诊生理参数系统调查”数据库中符合条件的数据,依据日均纯酒精摄入量划分饮酒模式,通过简明健康状况调查问卷(medical outcomes study 36-item short-form health survey,SF-36)获得生命质量得分,采用最小二乘回归分析不同饮酒模式的生命质量得分差异。结果纳入样本1994例,其中男性654例,女性1340例;年龄为31.7(22.0,37.0)岁。不饮酒模式、前饮酒模式、适度饮酒模式、中度饮酒模式、重度饮酒模式分别有1375人、74人、368人、90人、87人。5种饮酒模式比较,性别、年龄、婚姻情况、学历、主观经济状况、家庭人均实际收入、家庭成员、BMI、家族史、合并慢性病、饮茶情况、吸烟情况、睡眠习惯、劳逸情况、运动习惯的组间差异均有统计学意义(均P<0.05)。控制混杂变量的结果显示,5种饮酒模式的SF-36总分、心理领域以及下属的社会功能、情感职能、精神健康维度得分组间差异均有统计学意义(均P<0.05)。差异性检验与最小临床重要差值共同表明,不饮酒模式的生命质量最好,重度饮酒模式次之,其次是中度、适度饮酒模式,前饮酒模式最差,尤其在心理领域及其下属维度。结论相较于不饮酒模式,前饮酒模式生命质量最差,重度饮酒模式得分虽高,但考虑到其他健康结局,建议人群减少饮酒或保持不饮酒,以获得较大的健康效益。
文摘目的 了解某集团旗下养老院护理员的生命质量现状及其影响因素。方法 2022年2—4月随机抽取某集团位于深圳的3家养老院共153名护工,采用一般状况调查问卷和中文版36条简明健康状况调查表(the medical outcomes study36-item short form health survey,SF-36)对护理员进行自评量表式调查。利用Excel 2016软件和SPSS 26.0软件进行数据收集和解析,采用t检验、单因素方差分析、多元逐步回归分析进行统计学分析。结果 153名被调查者生命质量得分为(70.50±7.34)分,其中生理健康领域得分为(74.81±9.75)分,心理健康领域得分为(68.07±7.09)分。单因素方差分析和多元逐步回归分析显示,性别、婚姻状况、睡眠质量、饮食状况、薪酬满意度及是否上夜班均是影响养老院护工生命质量的主要影响因素(均P<0.05)。结论 养老院护理员的生命质量水平较低,需进一步提高。集团应适当提高护理团队的男性比例,加强对护理员的心理疏导,适当提高薪酬水平,完善绩效考核体系并提高绩效奖励,注重员工关怀,适当发放员工福利。
